LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
 3
J22
 72
hr
 1235 3379 4583 0.7372 0.7022
MDA-MB-231 WZ-4-145
1.11
uM
LJP6
 1
J21
 72
hr
 1235 2921 4355 0.6706 0.6052
MDA-MB-231 WZ-4-145
1.11
uM
LJP6
 2
J21
 72
hr
 1235 2944 4277 0.6883 0.6235
MDA-MB-231 WZ-4-145
1.11
uM
LJP6
 3
J21
 72
hr
 1235 3088 4583 0.6737 0.6230
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 1
J20
 72
hr
 1235 2394 4355 0.5496 0.4388
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 2
J20
 72
hr
 1235 2488 4277 0.5817 0.4779
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 3
J20
 72
hr
 1235 2576 4583 0.5620 0.4746
MDA-MB-231 WZ-4-145
10
uM
LJP6
 1
J19
 72
hr
 1235 549 4355 0.1260 -0.3602
MDA-MB-231 WZ-4-145
10
uM
LJP6
 2
J19
 72
hr
 1235 509 4277 0.1190 -0.3906
MDA-MB-231 WZ-4-145
10
uM
LJP6
 3
J19
 72
hr
 1235 599 4583 0.1307 -0.3183
MDA-MB-231 WZ3105
0.04
uM
LJP5
 1
D24
 72
hr
 1235 506 4474 0.1131 -0.3819
MDA-MB-231 WZ3105
0.04
uM
LJP5
 2
D24
 72
hr
 1235 460 4578 0.1005 -0.4074
MDA-MB-231 WZ3105
0.04
uM
LJP5
 3
D24
 72
hr
 1235 528 4929 0.1071 -0.3470
MDA-MB-231 WZ3105
0.12
uM
LJP5
 1
D23
 72
hr
 1235 492 4474 0.1100 -0.3912
MDA-MB-231 WZ3105
0.12
uM
LJP5
 2
D23
 72
hr
 1235 476 4578 0.1040 -0.3965
MDA-MB-231 WZ3105
0.12
uM
LJP5
 3
D23
 72
hr
 1235 446 4929 0.0905 -0.3999
MDA-MB-231 WZ3105
0.37
uM
LJP5
 1
D22
 72
hr
 1235 418 4474 0.0934 -0.4424
MDA-MB-231 WZ3105
0.37
uM
LJP5
 2
D22
 72
hr
 1235 461 4578 0.1007 -0.4067
MDA-MB-231 WZ3105
0.37
uM
LJP5
 3
D22
 72
hr
 1235 505 4929 0.1025 -0.3614
MDA-MB-231 WZ3105
1.11
uM
LJP5
 1
D21
 72
hr
 1235 431 4474 0.0963 -0.4331
MDA-MB-231 WZ3105
1.11
uM
LJP5
 2
D21
 72
hr
 1235 503 4578 0.1099 -0.3786
MDA-MB-231 WZ3105
1.11
uM
LJP5
 3
D21
 72
hr
 1235 405 4929 0.0822 -0.4282
MDA-MB-231 WZ3105
3.33
uM
LJP5
 1
D20
 72
hr
 1235 521 4474 0.1164 -0.3721
MDA-MB-231 WZ3105
3.33
uM
LJP5
 2
D20
 72
hr
 1235 493 4578 0.1077 -0.3852
MDA-MB-231 WZ3105
3.33
uM
LJP5
 3
D20
 72
hr
 1235 541 4929 0.1098 -0.3390