LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 CGP60474
10
uM
LJP6
 2
G01
 72
hr
 1235 165 4277 0.0386 -0.6751
MDA-MB-231 CGP60474
10
uM
LJP6
 3
G01
 72
hr
 1235 514 4583 0.1121 -0.3713
MDA-MB-231 CGP60474
10
uM
LJP5
 1
F01
 72
hr
 1235 403 4474 0.0901 -0.4532
MDA-MB-231 CGP60474
10
uM
LJP5
 2
F01
 72
hr
 1235 409 4578 0.0893 -0.4431
MDA-MB-231 CGP60474
10
uM
LJP5
 3
F01
 72
hr
 1235 552 4929 0.1120 -0.3323
MDA-MB-231 PD173074
0.04
uM
LJP6
 1
I12
 72
hr
 1235 4491 4355 1.0310 1.0339
MDA-MB-231 PD173074
0.04
uM
LJP6
 2
I12
 72
hr
 1235 4707 4277 1.1004 1.1098
MDA-MB-231 PD173074
0.04
uM
LJP6
 3
I12
 72
hr
 1235 4786 4583 1.0442 1.0463
MDA-MB-231 PD173074
0.12
uM
LJP6
 1
I11
 72
hr
 1235 4511 4355 1.0356 1.0389
MDA-MB-231 PD173074
0.12
uM
LJP6
 2
I11
 72
hr
 1235 4850 4277 1.1339 1.1453
MDA-MB-231 PD173074
0.12
uM
LJP6
 3
I11
 72
hr
 1235 4723 4583 1.0305 1.0320
MDA-MB-231 PD173074
0.37
uM
LJP6
 1
I10
 72
hr
 1235 4978 4355 1.1428 1.1524
MDA-MB-231 PD173074
0.37
uM
LJP6
 2
I10
 72
hr
 1235 5433 4277 1.2702 1.2857
MDA-MB-231 PD173074
0.37
uM
LJP6
 3
I10
 72
hr
 1235 4825 4583 1.0527 1.0551
MDA-MB-231 PD173074
1.11
uM
LJP6
 1
I09
 72
hr
 1235 4983 4355 1.1440 1.1536
MDA-MB-231 PD173074
1.11
uM
LJP6
 2
I09
 72
hr
 1235 5218 4277 1.2199 1.2347
MDA-MB-231 PD173074
1.11
uM
LJP6
 3
I09
 72
hr
 1235 4549 4583 0.9925 0.9921
MDA-MB-231 PD173074
3.33
uM
LJP6
 1
I08
 72
hr
 1235 4588 4355 1.0533 1.0579
MDA-MB-231 PD173074
3.33
uM
LJP6
 2
I08
 72
hr
 1235 4859 4277 1.1360 1.1476
MDA-MB-231 PD173074
3.33
uM
LJP6
 3
I08
 72
hr
 1235 4497 4583 0.9812 0.9800
MDA-MB-231 PD173074
10
uM
LJP6
 1
I07
 72
hr
 1235 1855 4355 0.4259 0.2504
MDA-MB-231 PD173074
10
uM
LJP6
 2
I07
 72
hr
 1235 1308 4277 0.3058 0.0321
MDA-MB-231 PD173074
10
uM
LJP6
 3
I07
 72
hr
 1235 1710 4583 0.3731 0.1873
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 1
A24
 72
hr
 1235 4487 4474 1.0027 1.0030
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 2
A24
 72
hr
 1235 4340 4578 0.9479 0.9442