LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 10 of 15: Cell count and normalized growth rate inhibition values within biological replicate 3. - Dataset (ID:20247)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 3
A24
 72
hr
 1235 4679 4929 0.9492 0.9485
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 1
A23
 72
hr
 1235 4471 4474 0.9992 0.9991
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 2
A23
 72
hr
 1235 4454 4578 0.9728 0.9710
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 3
A23
 72
hr
 1235 4501 4929 0.9131 0.9110
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 1
A22
 72
hr
 1235 4005 4474 0.8950 0.8840
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 2
A22
 72
hr
 1235 4122 4578 0.9003 0.8918
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 3
A22
 72
hr
 1235 4034 4929 0.8184 0.8089
MDA-MB-231 Crizotinib
1.11
uM
LJP5
 1
A21
 72
hr
 1235 2245 4474 0.5017 0.3793
MDA-MB-231 Crizotinib
1.11
uM
LJP5
 2
A21
 72
hr
 1235 2076 4578 0.4534 0.3159
MDA-MB-231 Crizotinib
1.11
uM
LJP5
 3
A21
 72
hr
 1235 2282 4929 0.4630 0.3597
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 1
A20
 72
hr
 1235 1456 4474 0.3254 0.0923
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 2
A20
 72
hr
 1235 1396 4578 0.3049 0.0666
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 3
A20
 72
hr
 1235 1411 4929 0.2863 0.0686
MDA-MB-231 Crizotinib
10
uM
LJP5
 1
A19
 72
hr
 1235 926 4474 0.2069 -0.1441
MDA-MB-231 Crizotinib
10
uM
LJP5
 2
A19
 72
hr
 1235 920 4578 0.2009 -0.1447
MDA-MB-231 Crizotinib
10
uM
LJP5
 3
A19
 72
hr
 1235 971 4929 0.1970 -0.1139
MDA-MB-231 BMS345541
0.04
uM
LJP6
 1
D06
 72
hr
 1235 4421 4355 1.0149 1.0164
MDA-MB-231 BMS345541
0.04
uM
LJP6
 2
D06
 72
hr
 1235 4228 4277 0.9885 0.9871
MDA-MB-231 BMS345541
0.04
uM
LJP6
 3
D06
 72
hr
 1235 4342 4583 0.9473 0.9436
MDA-MB-231 BMS345541
0.12
uM
LJP6
 1
D05
 72
hr
 1235 3706 4355 0.8508 0.8299
MDA-MB-231 BMS345541
0.12
uM
LJP6
 2
D05
 72
hr
 1235 3414 4277 0.7982 0.7635
MDA-MB-231 BMS345541
0.12
uM
LJP6
 3
D05
 72
hr
 1235 4257 4583 0.9288 0.9234
MDA-MB-231 BMS345541
0.37
uM
LJP6
 1
D04
 72
hr
 1235 3687 4355 0.8464 0.8247
MDA-MB-231 BMS345541
0.37
uM
LJP6
 2
D04
 72
hr
 1235 3618 4277 0.8459 0.8215
MDA-MB-231 BMS345541
0.37
uM
LJP6
 3
D04
 72
hr
 1235 3758 4583 0.8199 0.8006