LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | CHIR-99021 | 10 | uM | LJP6 | 1 | P13 | 72 | hr | 1694 | 8421 | 11220 | 0.7505 | 0.8002 |
| MCF 10A | CHIR-99021 | 10 | uM | LJP6 | 2 | P13 | 72 | hr | 1694 | 9959 | 11309 | 0.8806 | 0.9093 |
| MCF 10A | CHIR-99021 | 10 | uM | LJP6 | 3 | P13 | 72 | hr | 1694 | 8948 | 11121 | 0.8046 | 0.8461 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 1 | J12 | 72 | hr | 1694 | 11816 | 11220 | 1.0530 | 1.0383 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 2 | J12 | 72 | hr | 1694 | 11730 | 11309 | 1.0372 | 1.0268 |
| MCF 10A | Linifanib | 0.04 | uM | LJP6 | 3 | J12 | 72 | hr | 1694 | 11557 | 11121 | 1.0392 | 1.0285 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 1 | J11 | 72 | hr | 1694 | 11877 | 11220 | 1.0585 | 1.0421 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 2 | J11 | 72 | hr | 1694 | 12019 | 11309 | 1.0627 | 1.0449 |
| MCF 10A | Linifanib | 0.12 | uM | LJP6 | 3 | J11 | 72 | hr | 1694 | 11480 | 11121 | 1.0323 | 1.0235 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 1 | J10 | 72 | hr | 1694 | 11457 | 11220 | 1.0210 | 1.0153 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 2 | J10 | 72 | hr | 1694 | 11395 | 11309 | 1.0076 | 1.0055 |
| MCF 10A | Linifanib | 0.37 | uM | LJP6 | 3 | J10 | 72 | hr | 1694 | 11404 | 11121 | 1.0254 | 1.0186 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 1 | J09 | 72 | hr | 1694 | 11741 | 11220 | 1.0463 | 1.0335 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 2 | J09 | 72 | hr | 1694 | 11458 | 11309 | 1.0131 | 1.0096 |
| MCF 10A | Linifanib | 1.11 | uM | LJP6 | 3 | J09 | 72 | hr | 1694 | 11087 | 11121 | 0.9969 | 0.9977 |
| MCF 10A | Linifanib | 3.33 | uM | LJP6 | 1 | J08 | 72 | hr | 1694 | 11116 | 11220 | 0.9907 | 0.9931 |
| MCF 10A | Linifanib | 3.33 | uM | LJP6 | 2 | J08 | 72 | hr | 1694 | 11130 | 11309 | 0.9841 | 0.9884 |
| MCF 10A | Linifanib | 3.33 | uM | LJP6 | 3 | J08 | 72 | hr | 1694 | 10812 | 11121 | 0.9722 | 0.9793 |
| MCF 10A | Linifanib | 10 | uM | LJP6 | 1 | J07 | 72 | hr | 1694 | 9748 | 11220 | 0.8687 | 0.8994 |
| MCF 10A | Linifanib | 10 | uM | LJP6 | 2 | J07 | 72 | hr | 1694 | 9355 | 11309 | 0.8272 | 0.8662 |
| MCF 10A | Linifanib | 10 | uM | LJP6 | 3 | J07 | 72 | hr | 1694 | 9061 | 11121 | 0.8148 | 0.8546 |
| MCF 10A | PIK-93 | 0.04 | uM | LJP5 | 1 | K18 | 72 | hr | 1694 | 11056 | 11042 | 1.0012 | 1.0009 |
| MCF 10A | PIK-93 | 0.04 | uM | LJP5 | 2 | K18 | 72 | hr | 1694 | 11119 | 11099 | 1.0018 | 1.0013 |
| MCF 10A | PIK-93 | 0.04 | uM | LJP5 | 3 | K18 | 72 | hr | 1694 | 11257 | 11168 | 1.0079 | 1.0058 |
| MCF 10A | PIK-93 | 0.12 | uM | LJP5 | 1 | K17 | 72 | hr | 1694 | 11148 | 11042 | 1.0096 | 1.0071 |