LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Omipalisib
10
uM
LJP6
 3
N01
 72
hr
 1694 1022 11121 0.0919 -0.1699
MCF 10A Buparlisib
0.04
uM
LJP5
 1
H06
 72
hr
 1694 11152 11042 1.0099 1.0073
MCF 10A Buparlisib
0.04
uM
LJP5
 2
H06
 72
hr
 1694 10848 11099 0.9773 0.9832
MCF 10A Buparlisib
0.04
uM
LJP5
 3
H06
 72
hr
 1694 11455 11168 1.0257 1.0187
MCF 10A Buparlisib
0.12
uM
LJP5
 1
H05
 72
hr
 1694 10822 11042 0.9800 0.9852
MCF 10A Buparlisib
0.12
uM
LJP5
 2
H05
 72
hr
 1694 10605 11099 0.9555 0.9667
MCF 10A Buparlisib
0.12
uM
LJP5
 3
H05
 72
hr
 1694 10898 11168 0.9758 0.9821
MCF 10A Buparlisib
0.37
uM
LJP5
 1
H04
 72
hr
 1694 9579 11042 0.8675 0.8976
MCF 10A Buparlisib
0.37
uM
LJP5
 2
H04
 72
hr
 1694 9676 11099 0.8718 0.9013
MCF 10A Buparlisib
0.37
uM
LJP5
 3
H04
 72
hr
 1694 9878 11168 0.8845 0.9118
MCF 10A Buparlisib
1.11
uM
LJP5
 1
H03
 72
hr
 1694 4967 11042 0.4498 0.4884
MCF 10A Buparlisib
1.11
uM
LJP5
 2
H03
 72
hr
 1694 4922 11099 0.4434 0.4818
MCF 10A Buparlisib
1.11
uM
LJP5
 3
H03
 72
hr
 1694 5522 11168 0.4944 0.5438
MCF 10A Buparlisib
3.33
uM
LJP5
 1
H02
 72
hr
 1694 1652 11042 0.1496 -0.0093
MCF 10A Buparlisib
3.33
uM
LJP5
 2
H02
 72
hr
 1694 1814 11099 0.1634 0.0255
MCF 10A Buparlisib
3.33
uM
LJP5
 3
H02
 72
hr
 1694 1930 11168 0.1728 0.0490
MCF 10A Buparlisib
10
uM
LJP5
 1
H01
 72
hr
 1694 586 11042 0.0531 -0.3247
MCF 10A Buparlisib
10
uM
LJP5
 2
H01
 72
hr
 1694 591 11099 0.0532 -0.3218
MCF 10A Buparlisib
10
uM
LJP5
 3
H01
 72
hr
 1694 668 11168 0.0598 -0.2897
MCF 10A XL147
0.04
uM
LJP5
 1
G12
 72
hr
 1694 11159 11042 1.0106 1.0078
MCF 10A XL147
0.04
uM
LJP5
 2
G12
 72
hr
 1694 11489 11099 1.0351 1.0256
MCF 10A XL147
0.04
uM
LJP5
 3
G12
 72
hr
 1694 11292 11168 1.0111 1.0081
MCF 10A XL147
0.12
uM
LJP5
 1
G11
 72
hr
 1694 10703 11042 0.9693 0.9771
MCF 10A XL147
0.12
uM
LJP5
 2
G11
 72
hr
 1694 10987 11099 0.9899 0.9925
MCF 10A XL147
0.12
uM
LJP5
 3
G11
 72
hr
 1694 10764 11168 0.9638 0.9731