LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A PIK-93
0.12
uM
LJP5
 2
K17
 72
hr
 1694 11178 11099 1.0071 1.0052
MCF 10A PIK-93
0.12
uM
LJP5
 3
K17
 72
hr
 1694 11481 11168 1.0280 1.0204
MCF 10A PIK-93
0.37
uM
LJP5
 1
K16
 72
hr
 1694 11344 11042 1.0273 1.0200
MCF 10A PIK-93
0.37
uM
LJP5
 2
K16
 72
hr
 1694 11265 11099 1.0149 1.0109
MCF 10A PIK-93
0.37
uM
LJP5
 3
K16
 72
hr
 1694 11444 11168 1.0247 1.0180
MCF 10A PIK-93
1.11
uM
LJP5
 1
K15
 72
hr
 1694 10975 11042 0.9939 0.9955
MCF 10A PIK-93
1.11
uM
LJP5
 2
K15
 72
hr
 1694 10777 11099 0.9709 0.9784
MCF 10A PIK-93
1.11
uM
LJP5
 3
K15
 72
hr
 1694 10900 11168 0.9760 0.9822
MCF 10A PIK-93
3.33
uM
LJP5
 1
K14
 72
hr
 1694 9333 11042 0.8452 0.8794
MCF 10A PIK-93
3.33
uM
LJP5
 2
K14
 72
hr
 1694 9389 11099 0.8459 0.8803
MCF 10A PIK-93
3.33
uM
LJP5
 3
K14
 72
hr
 1694 9706 11168 0.8691 0.8995
MCF 10A PIK-93
10
uM
LJP5
 1
K13
 72
hr
 1694 5311 11042 0.4810 0.5258
MCF 10A PIK-93
10
uM
LJP5
 2
K13
 72
hr
 1694 5415 11099 0.4879 0.5349
MCF 10A PIK-93
10
uM
LJP5
 3
K13
 72
hr
 1694 5696 11168 0.5100 0.5615
MCF 10A Dactolisib
0.04
uM
LJP5
 1
M18
 72
hr
 1694 6469 11042 0.5858 0.6412
MCF 10A Dactolisib
0.04
uM
LJP5
 2
M18
 72
hr
 1694 6370 11099 0.5739 0.6297
MCF 10A Dactolisib
0.04
uM
LJP5
 3
M18
 72
hr
 1694 7014 11168 0.6280 0.6857
MCF 10A Dactolisib
0.12
uM
LJP5
 1
M17
 72
hr
 1694 4241 11042 0.3841 0.4040
MCF 10A Dactolisib
0.12
uM
LJP5
 2
M17
 72
hr
 1694 3820 11099 0.3442 0.3496
MCF 10A Dactolisib
0.12
uM
LJP5
 3
M17
 72
hr
 1694 4235 11168 0.3792 0.4004
MCF 10A Dactolisib
0.37
uM
LJP5
 1
M16
 72
hr
 1694 2947 11042 0.2669 0.2271
MCF 10A Dactolisib
0.37
uM
LJP5
 2
M16
 72
hr
 1694 2563 11099 0.2309 0.1649
MCF 10A Dactolisib
0.37
uM
LJP5
 3
M16
 72
hr
 1694 3127 11168 0.2800 0.2526
MCF 10A Dactolisib
1.11
uM
LJP5
 1
M15
 72
hr
 1694 3064 11042 0.2775 0.2449
MCF 10A Dactolisib
1.11
uM
LJP5
 2
M15
 72
hr
 1694 2584 11099 0.2328 0.1684