LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Celastrol | 0.12 | uM | LJP6 | 1 | G11 | 72 | hr | 1389 | 5299 | 5147 | 1.0295 | 1.0310 |
| MCF7 | Celastrol | 0.12 | uM | LJP6 | 2 | G11 | 72 | hr | 1389 | 5527 | 5447 | 1.0145 | 1.0147 |
| MCF7 | Celastrol | 0.12 | uM | LJP6 | 3 | G11 | 72 | hr | 1389 | 5996 | 5740 | 1.0445 | 1.0430 |
| MCF7 | Celastrol | 0.37 | uM | LJP6 | 1 | G10 | 72 | hr | 1389 | 3434 | 5147 | 0.6672 | 0.6144 |
| MCF7 | Celastrol | 0.37 | uM | LJP6 | 2 | G10 | 72 | hr | 1389 | 4083 | 5447 | 0.7495 | 0.7278 |
| MCF7 | Celastrol | 0.37 | uM | LJP6 | 3 | G10 | 72 | hr | 1389 | 3386 | 5740 | 0.5898 | 0.5454 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 1 | G09 | 72 | hr | 1389 | 2299 | 5147 | 0.4467 | 0.3056 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 2 | G09 | 72 | hr | 1389 | 1979 | 5447 | 0.3633 | 0.1967 |
| MCF7 | Celastrol | 1.11 | uM | LJP6 | 3 | G09 | 72 | hr | 1389 | 1975 | 5740 | 0.3441 | 0.1876 |
| MCF7 | Celastrol | 3.33 | uM | LJP6 | 1 | G08 | 72 | hr | 1389 | 1172 | 5147 | 0.2277 | -0.0860 |
| MCF7 | Celastrol | 3.33 | uM | LJP6 | 2 | G08 | 72 | hr | 1389 | 1297 | 5447 | 0.2381 | -0.0342 |
| MCF7 | Celastrol | 3.33 | uM | LJP6 | 3 | G08 | 72 | hr | 1389 | 1498 | 5740 | 0.2610 | 0.0376 |
| MCF7 | Celastrol | 10 | uM | LJP6 | 1 | G07 | 72 | hr | 1389 | 976 | 5147 | 0.1896 | -0.1704 |
| MCF7 | Celastrol | 10 | uM | LJP6 | 2 | G07 | 72 | hr | 1389 | 833 | 5447 | 0.1529 | -0.2285 |
| MCF7 | Celastrol | 10 | uM | LJP6 | 3 | G07 | 72 | hr | 1389 | 1330 | 5740 | 0.2317 | -0.0210 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 1 | J12 | 72 | hr | 1389 | 6293 | 5772 | 1.0902 | 1.0858 |
| MCF7 | SU11274 | 0.04 | uM | LJP5 | 3 | J12 | 72 | hr | 1389 | 6545 | 6038 | 1.0839 | 1.0774 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 1 | J11 | 72 | hr | 1389 | 5862 | 5772 | 1.0155 | 1.0150 |
| MCF7 | SU11274 | 0.12 | uM | LJP5 | 3 | J11 | 72 | hr | 1389 | 6109 | 6038 | 1.0117 | 1.0110 |
| MCF7 | SU11274 | 0.37 | uM | LJP5 | 1 | J10 | 72 | hr | 1389 | 5903 | 5772 | 1.0226 | 1.0219 |
| MCF7 | SU11274 | 0.37 | uM | LJP5 | 3 | J10 | 72 | hr | 1389 | 6036 | 6038 | 0.9996 | 0.9996 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 1 | J09 | 72 | hr | 1389 | 4553 | 5772 | 0.7887 | 0.7819 |
| MCF7 | SU11274 | 1.11 | uM | LJP5 | 3 | J09 | 72 | hr | 1389 | 5321 | 6038 | 0.8812 | 0.8842 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 1 | J08 | 72 | hr | 1389 | 4265 | 5772 | 0.7389 | 0.7261 |
| MCF7 | SU11274 | 3.33 | uM | LJP5 | 3 | J08 | 72 | hr | 1389 | 4842 | 6038 | 0.8019 | 0.8022 |