LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | LDN-193189 | 0.12 | uM | LJP5 | 1 | G05 | 72 | hr | 1389 | 5228 | 5772 | 0.9057 | 0.9059 |
| MCF7 | LDN-193189 | 0.12 | uM | LJP5 | 3 | G05 | 72 | hr | 1389 | 5741 | 6038 | 0.9507 | 0.9529 |
| MCF7 | LDN-193189 | 0.37 | uM | LJP5 | 1 | G04 | 72 | hr | 1389 | 5545 | 5772 | 0.9606 | 0.9613 |
| MCF7 | LDN-193189 | 0.37 | uM | LJP5 | 3 | G04 | 72 | hr | 1389 | 5983 | 6038 | 0.9908 | 0.9913 |
| MCF7 | LDN-193189 | 1.11 | uM | LJP5 | 1 | G03 | 72 | hr | 1389 | 5153 | 5772 | 0.8927 | 0.8925 |
| MCF7 | LDN-193189 | 1.11 | uM | LJP5 | 3 | G03 | 72 | hr | 1389 | 5412 | 6038 | 0.8963 | 0.8993 |
| MCF7 | LDN-193189 | 3.33 | uM | LJP5 | 1 | G02 | 72 | hr | 1389 | 3199 | 5772 | 0.5542 | 0.5007 |
| MCF7 | LDN-193189 | 3.33 | uM | LJP5 | 3 | G02 | 72 | hr | 1389 | 3442 | 6038 | 0.5700 | 0.5342 |
| MCF7 | LDN-193189 | 10 | uM | LJP5 | 1 | G01 | 72 | hr | 1389 | 531 | 5772 | 0.0920 | -0.3737 |
| MCF7 | LDN-193189 | 10 | uM | LJP5 | 3 | G01 | 72 | hr | 1389 | 542 | 6038 | 0.0898 | -0.3585 |
| MCF7 | PF431396 | 0.04 | uM | LJP5 | 1 | E12 | 72 | hr | 1389 | 4675 | 5772 | 0.8099 | 0.8050 |
| MCF7 | PF431396 | 0.04 | uM | LJP5 | 3 | E12 | 72 | hr | 1389 | 4982 | 6038 | 0.8250 | 0.8266 |
| MCF7 | PF431396 | 0.12 | uM | LJP5 | 1 | E11 | 72 | hr | 1389 | 3470 | 5772 | 0.6011 | 0.5613 |
| MCF7 | PF431396 | 0.12 | uM | LJP5 | 3 | E11 | 72 | hr | 1389 | 3734 | 6038 | 0.6184 | 0.5943 |
| MCF7 | PF431396 | 0.37 | uM | LJP5 | 1 | E10 | 72 | hr | 1389 | 2101 | 5772 | 0.3640 | 0.2231 |
| MCF7 | PF431396 | 0.37 | uM | LJP5 | 3 | E10 | 72 | hr | 1389 | 2478 | 6038 | 0.4104 | 0.3139 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 1 | E09 | 72 | hr | 1389 | 1409 | 5772 | 0.2441 | 0.0070 |
| MCF7 | PF431396 | 1.11 | uM | LJP5 | 3 | E09 | 72 | hr | 1389 | 1770 | 6038 | 0.2931 | 0.1211 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 1 | E08 | 72 | hr | 1389 | 1332 | 5772 | 0.2308 | -0.0202 |
| MCF7 | PF431396 | 3.33 | uM | LJP5 | 3 | E08 | 72 | hr | 1389 | 1478 | 6038 | 0.2448 | 0.0297 |
| MCF7 | PF431396 | 10 | uM | LJP5 | 1 | E07 | 72 | hr | 1389 | 680 | 5772 | 0.1178 | -0.2936 |
| MCF7 | PF431396 | 10 | uM | LJP5 | 3 | E07 | 72 | hr | 1389 | 650 | 6038 | 0.1076 | -0.3011 |
| MCF7 | Celastrol | 0.04 | uM | LJP6 | 1 | G12 | 72 | hr | 1389 | 6372 | 5147 | 1.2380 | 1.2392 |
| MCF7 | Celastrol | 0.04 | uM | LJP6 | 2 | G12 | 72 | hr | 1389 | 6246 | 5447 | 1.1465 | 1.1436 |
| MCF7 | Celastrol | 0.04 | uM | LJP6 | 3 | G12 | 72 | hr | 1389 | 5742 | 5740 | 1.0003 | 1.0003 |