LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | SU11274 | 10 | uM | LJP5 | 1 | J07 | 72 | hr | 1389 | 1593 | 5772 | 0.2760 | 0.0689 |
| MCF7 | SU11274 | 10 | uM | LJP5 | 3 | J07 | 72 | hr | 1389 | 1786 | 6038 | 0.2958 | 0.1259 |
| MCF7 | Canertinib | 0.04 | uM | LJP6 | 1 | H12 | 72 | hr | 1389 | 4339 | 5147 | 0.8430 | 0.8272 |
| MCF7 | Canertinib | 0.04 | uM | LJP6 | 2 | H12 | 72 | hr | 1389 | 6102 | 5447 | 1.1201 | 1.1184 |
| MCF7 | Canertinib | 0.04 | uM | LJP6 | 3 | H12 | 72 | hr | 1389 | 5794 | 5740 | 1.0093 | 1.0091 |
| MCF7 | Canertinib | 0.12 | uM | LJP6 | 1 | H11 | 72 | hr | 1389 | 3973 | 5147 | 0.7719 | 0.7439 |
| MCF7 | Canertinib | 0.12 | uM | LJP6 | 2 | H11 | 72 | hr | 1389 | 5383 | 5447 | 0.9881 | 0.9879 |
| MCF7 | Canertinib | 0.12 | uM | LJP6 | 3 | H11 | 72 | hr | 1389 | 5075 | 5740 | 0.8841 | 0.8832 |
| MCF7 | Canertinib | 0.37 | uM | LJP6 | 1 | H10 | 72 | hr | 1389 | 3908 | 5147 | 0.7593 | 0.7288 |
| MCF7 | Canertinib | 0.37 | uM | LJP6 | 2 | H10 | 72 | hr | 1389 | 5064 | 5447 | 0.9295 | 0.9272 |
| MCF7 | Canertinib | 0.37 | uM | LJP6 | 3 | H10 | 72 | hr | 1389 | 4896 | 5740 | 0.8529 | 0.8504 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 1 | H09 | 72 | hr | 1389 | 3017 | 5147 | 0.5862 | 0.5075 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 2 | H09 | 72 | hr | 1389 | 4243 | 5447 | 0.7788 | 0.7619 |
| MCF7 | Canertinib | 1.11 | uM | LJP6 | 3 | H09 | 72 | hr | 1389 | 4388 | 5740 | 0.7644 | 0.7540 |
| MCF7 | Canertinib | 3.33 | uM | LJP6 | 1 | H08 | 72 | hr | 1389 | 2867 | 5147 | 0.5570 | 0.4674 |
| MCF7 | Canertinib | 3.33 | uM | LJP6 | 2 | H08 | 72 | hr | 1389 | 3812 | 5447 | 0.6997 | 0.6687 |
| MCF7 | Canertinib | 3.33 | uM | LJP6 | 3 | H08 | 72 | hr | 1389 | 3809 | 5740 | 0.6635 | 0.6369 |
| MCF7 | Canertinib | 10 | uM | LJP6 | 1 | H07 | 72 | hr | 1389 | 580 | 5147 | 0.1127 | -0.3701 |
| MCF7 | Canertinib | 10 | uM | LJP6 | 2 | H07 | 72 | hr | 1389 | 574 | 5447 | 0.1054 | -0.3613 |
| MCF7 | Canertinib | 10 | uM | LJP6 | 3 | H07 | 72 | hr | 1389 | 544 | 5740 | 0.0948 | -0.3674 |
| MCF7 | NVP-AEW541 | 0.04 | uM | LJP5 | 1 | E18 | 72 | hr | 1389 | 6145 | 5772 | 1.0645 | 1.0618 |
| MCF7 | NVP-AEW541 | 0.04 | uM | LJP5 | 3 | E18 | 72 | hr | 1389 | 5693 | 6038 | 0.9428 | 0.9452 |
| MCF7 | NVP-AEW541 | 0.12 | uM | LJP5 | 1 | E17 | 72 | hr | 1389 | 5135 | 5772 | 0.8896 | 0.8893 |
| MCF7 | NVP-AEW541 | 0.12 | uM | LJP5 | 3 | E17 | 72 | hr | 1389 | 5758 | 6038 | 0.9536 | 0.9556 |
| MCF7 | NVP-AEW541 | 0.37 | uM | LJP5 | 1 | E16 | 72 | hr | 1389 | 2795 | 5772 | 0.4842 | 0.4053 |