LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Imatinib
3.33
uM
LJP6
 2
N14
 72
hr
 1694 11926 11309 1.0545 1.0391
MCF 10A Imatinib
3.33
uM
LJP6
 3
N14
 72
hr
 1694 11314 11121 1.0173 1.0127
MCF 10A Imatinib
10
uM
LJP6
 1
N13
 72
hr
 1694 10939 11220 0.9749 0.9814
MCF 10A Imatinib
10
uM
LJP6
 2
N13
 72
hr
 1694 11562 11309 1.0223 1.0162
MCF 10A Imatinib
10
uM
LJP6
 3
N13
 72
hr
 1694 11521 11121 1.0360 1.0262
MCF 10A NVP-TAE684
0.04
uM
LJP6
 1
K18
 72
hr
 1694 9788 11220 0.8723 0.9023
MCF 10A NVP-TAE684
0.04
uM
LJP6
 2
K18
 72
hr
 1694 10238 11309 0.9053 0.9286
MCF 10A NVP-TAE684
0.04
uM
LJP6
 3
K18
 72
hr
 1694 9869 11121 0.8874 0.9139
MCF 10A NVP-TAE684
0.12
uM
LJP6
 1
K17
 72
hr
 1694 9298 11220 0.8286 0.8668
MCF 10A NVP-TAE684
0.12
uM
LJP6
 2
K17
 72
hr
 1694 9614 11309 0.8501 0.8849
MCF 10A NVP-TAE684
0.12
uM
LJP6
 3
K17
 72
hr
 1694 9302 11121 0.8364 0.8726
MCF 10A NVP-TAE684
0.37
uM
LJP6
 1
K16
 72
hr
 1694 6937 11220 0.6182 0.6767
MCF 10A NVP-TAE684
0.37
uM
LJP6
 2
K16
 72
hr
 1694 7231 11309 0.6394 0.6987
MCF 10A NVP-TAE684
0.37
uM
LJP6
 3
K16
 72
hr
 1694 6624 11121 0.5956 0.6525
MCF 10A NVP-TAE684
1.11
uM
LJP6
 1
K15
 72
hr
 1694 5905 11220 0.5263 0.5806
MCF 10A NVP-TAE684
1.11
uM
LJP6
 2
K15
 72
hr
 1694 6555 11309 0.5796 0.6389
MCF 10A NVP-TAE684
1.11
uM
LJP6
 3
K15
 72
hr
 1694 5760 11121 0.5179 0.5695
MCF 10A NVP-TAE684
3.33
uM
LJP6
 1
K14
 72
hr
 1694 4738 11220 0.4223 0.4580
MCF 10A NVP-TAE684
3.33
uM
LJP6
 2
K14
 72
hr
 1694 4935 11309 0.4364 0.4775
MCF 10A NVP-TAE684
3.33
uM
LJP6
 3
K14
 72
hr
 1694 4621 11121 0.4155 0.4472
MCF 10A NVP-TAE684
10
uM
LJP6
 1
K13
 72
hr
 1694 3417 11220 0.3045 0.2933
MCF 10A NVP-TAE684
10
uM
LJP6
 2
K13
 72
hr
 1694 2934 11309 0.2594 0.2220
MCF 10A NVP-TAE684
10
uM
LJP6
 3
K13
 72
hr
 1694 2549 11121 0.2292 0.1624
MCF 10A CGP60474
0.04
uM
LJP6
 1
G06
 72
hr
 1694 333 11220 0.0297 -0.4493
MCF 10A CGP60474
0.04
uM
LJP6
 2
G06
 72
hr
 1694 427 11309 0.0378 -0.3954