LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF 10A Tozasertib
0.37
uM
LJP5
 1
B16
 72
hr
 1694 1976 11042 0.1790 0.0585
MCF 10A Tozasertib
0.37
uM
LJP5
 2
B16
 72
hr
 1694 2109 11099 0.1900 0.0841
MCF 10A Tozasertib
0.37
uM
LJP5
 3
B16
 72
hr
 1694 2118 11168 0.1896 0.0855
MCF 10A Tozasertib
1.11
uM
LJP5
 1
B15
 72
hr
 1694 1947 11042 0.1763 0.0528
MCF 10A Tozasertib
1.11
uM
LJP5
 2
B15
 72
hr
 1694 1971 11099 0.1776 0.0574
MCF 10A Tozasertib
1.11
uM
LJP5
 3
B15
 72
hr
 1694 2002 11168 0.1793 0.0633
MCF 10A Tozasertib
3.33
uM
LJP5
 1
B14
 72
hr
 1694 1830 11042 0.1657 0.0289
MCF 10A Tozasertib
3.33
uM
LJP5
 2
B14
 72
hr
 1694 2177 11099 0.1961 0.0969
MCF 10A Tozasertib
3.33
uM
LJP5
 3
B14
 72
hr
 1694 1877 11168 0.1681 0.0384
MCF 10A Tozasertib
10
uM
LJP5
 1
B13
 72
hr
 1694 1676 11042 0.1518 -0.0040
MCF 10A Tozasertib
10
uM
LJP5
 2
B13
 72
hr
 1694 1898 11099 0.1710 0.0428
MCF 10A Tozasertib
10
uM
LJP5
 3
B13
 72
hr
 1694 1666 11168 0.1492 -0.0062
MCF 10A Imatinib
0.04
uM
LJP6
 1
N18
 72
hr
 1694 10926 11220 0.9737 0.9806
MCF 10A Imatinib
0.04
uM
LJP6
 2
N18
 72
hr
 1694 11436 11309 1.0112 1.0081
MCF 10A Imatinib
0.04
uM
LJP6
 3
N18
 72
hr
 1694 11052 11121 0.9938 0.9954
MCF 10A Imatinib
0.12
uM
LJP6
 1
N17
 72
hr
 1694 11164 11220 0.9949 0.9963
MCF 10A Imatinib
0.12
uM
LJP6
 2
N17
 72
hr
 1694 11533 11309 1.0198 1.0144
MCF 10A Imatinib
0.12
uM
LJP6
 3
N17
 72
hr
 1694 11056 11121 0.9941 0.9957
MCF 10A Imatinib
0.37
uM
LJP6
 1
N16
 72
hr
 1694 10862 11220 0.9680 0.9763
MCF 10A Imatinib
0.37
uM
LJP6
 2
N16
 72
hr
 1694 11568 11309 1.0229 1.0166
MCF 10A Imatinib
0.37
uM
LJP6
 3
N16
 72
hr
 1694 10914 11121 0.9814 0.9862
MCF 10A Imatinib
1.11
uM
LJP6
 1
N15
 72
hr
 1694 11086 11220 0.9880 0.9912
MCF 10A Imatinib
1.11
uM
LJP6
 2
N15
 72
hr
 1694 11599 11309 1.0256 1.0186
MCF 10A Imatinib
1.11
uM
LJP6
 3
N15
 72
hr
 1694 11081 11121 0.9964 0.9973
MCF 10A Imatinib
3.33
uM
LJP6
 1
N14
 72
hr
 1694 11122 11220 0.9912 0.9935