LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | SB590885 | 1.11 | uM | LJP5 | 3 | L15 | 72 | hr | 1694 | 11600 | 11168 | 1.0386 | 1.0281 |
| MCF 10A | SB590885 | 3.33 | uM | LJP5 | 1 | L14 | 72 | hr | 1694 | 11039 | 11042 | 0.9997 | 0.9998 |
| MCF 10A | SB590885 | 3.33 | uM | LJP5 | 2 | L14 | 72 | hr | 1694 | 10517 | 11099 | 0.9475 | 0.9606 |
| MCF 10A | SB590885 | 3.33 | uM | LJP5 | 3 | L14 | 72 | hr | 1694 | 10998 | 11168 | 0.9848 | 0.9887 |
| MCF 10A | SB590885 | 10 | uM | LJP5 | 1 | L13 | 72 | hr | 1694 | 7940 | 11042 | 0.7191 | 0.7704 |
| MCF 10A | SB590885 | 10 | uM | LJP5 | 2 | L13 | 72 | hr | 1694 | 7632 | 11099 | 0.6876 | 0.7420 |
| MCF 10A | SB590885 | 10 | uM | LJP5 | 3 | L13 | 72 | hr | 1694 | 8219 | 11168 | 0.7359 | 0.7868 |
| MCF 10A | Pictilisib | 0.04 | uM | LJP6 | 1 | D24 | 72 | hr | 1694 | 9622 | 11220 | 0.8575 | 0.8904 |
| MCF 10A | Pictilisib | 0.04 | uM | LJP6 | 2 | D24 | 72 | hr | 1694 | 10207 | 11309 | 0.9025 | 0.9265 |
| MCF 10A | Pictilisib | 0.04 | uM | LJP6 | 3 | D24 | 72 | hr | 1694 | 9942 | 11121 | 0.8940 | 0.9191 |
| MCF 10A | Pictilisib | 0.12 | uM | LJP6 | 1 | D23 | 72 | hr | 1694 | 9128 | 11220 | 0.8135 | 0.8542 |
| MCF 10A | Pictilisib | 0.12 | uM | LJP6 | 2 | D23 | 72 | hr | 1694 | 9513 | 11309 | 0.8412 | 0.8776 |
| MCF 10A | Pictilisib | 0.12 | uM | LJP6 | 3 | D23 | 72 | hr | 1694 | 9215 | 11121 | 0.8286 | 0.8662 |
| MCF 10A | Pictilisib | 0.37 | uM | LJP6 | 1 | D22 | 72 | hr | 1694 | 7119 | 11220 | 0.6344 | 0.6927 |
| MCF 10A | Pictilisib | 0.37 | uM | LJP6 | 2 | D22 | 72 | hr | 1694 | 7088 | 11309 | 0.6267 | 0.6863 |
| MCF 10A | Pictilisib | 0.37 | uM | LJP6 | 3 | D22 | 72 | hr | 1694 | 7826 | 11121 | 0.7037 | 0.7572 |
| MCF 10A | Pictilisib | 1.11 | uM | LJP6 | 1 | D21 | 72 | hr | 1694 | 4836 | 11220 | 0.4310 | 0.4690 |
| MCF 10A | Pictilisib | 1.11 | uM | LJP6 | 2 | D21 | 72 | hr | 1694 | 5155 | 11309 | 0.4558 | 0.5012 |
| MCF 10A | Pictilisib | 1.11 | uM | LJP6 | 3 | D21 | 72 | hr | 1694 | 5434 | 11121 | 0.4886 | 0.5362 |
| MCF 10A | Pictilisib | 3.33 | uM | LJP6 | 1 | D20 | 72 | hr | 1694 | 3617 | 11220 | 0.3223 | 0.3206 |
| MCF 10A | Pictilisib | 3.33 | uM | LJP6 | 2 | D20 | 72 | hr | 1694 | 3366 | 11309 | 0.2976 | 0.2849 |
| MCF 10A | Pictilisib | 3.33 | uM | LJP6 | 3 | D20 | 72 | hr | 1694 | 3835 | 11121 | 0.3448 | 0.3511 |
| MCF 10A | Pictilisib | 10 | uM | LJP6 | 1 | D19 | 72 | hr | 1694 | 2465 | 11220 | 0.2197 | 0.1474 |
| MCF 10A | Pictilisib | 10 | uM | LJP6 | 2 | D19 | 72 | hr | 1694 | 2208 | 11309 | 0.1952 | 0.1015 |
| MCF 10A | Pictilisib | 10 | uM | LJP6 | 3 | D19 | 72 | hr | 1694 | 2699 | 11121 | 0.2427 | 0.1871 |