LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD8330
0.37
uM
LJP5
 3
G22
 72
hr
 1311 1611 5010 0.3215 0.1121
MDA-MB-231 AZD8330
1.11
uM
LJP5
 1
G21
 72
hr
 1311 1546 5128 0.3015 0.0871
MDA-MB-231 AZD8330
1.11
uM
LJP5
 2
G21
 72
hr
 1311 1492 5100 0.2926 0.0679
MDA-MB-231 AZD8330
1.11
uM
LJP5
 3
G21
 72
hr
 1311 1506 5010 0.3006 0.0740
MDA-MB-231 AZD8330
3.33
uM
LJP5
 1
G20
 72
hr
 1311 1621 5128 0.3161 0.1136
MDA-MB-231 AZD8330
3.33
uM
LJP5
 2
G20
 72
hr
 1311 1620 5100 0.3177 0.1138
MDA-MB-231 AZD8330
3.33
uM
LJP5
 3
G20
 72
hr
 1311 1731 5010 0.3455 0.1542
MDA-MB-231 AZD8330
10
uM
LJP5
 1
G19
 72
hr
 1311 1519 5128 0.2962 0.0774
MDA-MB-231 AZD8330
10
uM
LJP5
 2
G19
 72
hr
 1311 1588 5100 0.3114 0.1025
MDA-MB-231 AZD8330
10
uM
LJP5
 3
G19
 72
hr
 1311 1654 5010 0.3301 0.1274
MDA-MB-231 TGX221
0.04
uM
LJP5
 1
H24
 72
hr
 1311 4450 5128 0.8677 0.8608
MDA-MB-231 TGX221
0.04
uM
LJP5
 2
H24
 72
hr
 1311 4107 5100 0.8053 0.7907
MDA-MB-231 TGX221
0.04
uM
LJP5
 3
H24
 72
hr
 1311 4195 5010 0.8372 0.8244
MDA-MB-231 TGX221
0.12
uM
LJP5
 1
H23
 72
hr
 1311 4555 5128 0.8882 0.8830
MDA-MB-231 TGX221
0.12
uM
LJP5
 2
H23
 72
hr
 1311 4378 5100 0.8584 0.8501
MDA-MB-231 TGX221
0.12
uM
LJP5
 3
H23
 72
hr
 1311 4225 5010 0.8432 0.8311
MDA-MB-231 TGX221
0.37
uM
LJP5
 1
H22
 72
hr
 1311 4505 5128 0.8785 0.8725
MDA-MB-231 TGX221
0.37
uM
LJP5
 2
H22
 72
hr
 1311 4690 5100 0.9196 0.9162
MDA-MB-231 TGX221
0.37
uM
LJP5
 3
H22
 72
hr
 1311 4353 5010 0.8687 0.8596
MDA-MB-231 TGX221
1.11
uM
LJP5
 1
H21
 72
hr
 1311 4396 5128 0.8572 0.8493
MDA-MB-231 TGX221
1.11
uM
LJP5
 2
H21
 72
hr
 1311 4251 5100 0.8335 0.8225
MDA-MB-231 TGX221
1.11
uM
LJP5
 3
H21
 72
hr
 1311 4287 5010 0.8555 0.8450
MDA-MB-231 TGX221
3.33
uM
LJP5
 1
H20
 72
hr
 1311 3462 5128 0.6751 0.6379
MDA-MB-231 TGX221
3.33
uM
LJP5
 2
H20
 72
hr
 1311 3336 5100 0.6541 0.6104
MDA-MB-231 TGX221
3.33
uM
LJP5
 3
H20
 72
hr
 1311 3600 5010 0.7184 0.6856