LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Linsitinib
1.11
uM
LJP5
 2
O21
 72
hr
 1311 4554 5100 0.8929 0.8877
MDA-MB-231 Linsitinib
1.11
uM
LJP5
 3
O21
 72
hr
 1311 4860 5010 0.9699 0.9686
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 1
O20
 72
hr
 1311 4703 5128 0.9171 0.9139
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 2
O20
 72
hr
 1311 4722 5100 0.9259 0.9229
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 3
O20
 72
hr
 1311 4801 5010 0.9581 0.9562
MDA-MB-231 Linsitinib
10
uM
LJP5
 1
O19
 72
hr
 1311 4279 5128 0.8344 0.8241
MDA-MB-231 Linsitinib
10
uM
LJP5
 2
O19
 72
hr
 1311 4139 5100 0.8116 0.7978
MDA-MB-231 Linsitinib
10
uM
LJP5
 3
O19
 72
hr
 1311 4027 5010 0.8037 0.7862
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 1
O18
 72
hr
 1311 5182 5128 1.0105 1.0106
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 2
O18
 72
hr
 1311 4915 5100 0.9637 0.9626
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 3
O18
 72
hr
 1311 5290 5010 1.0557 1.0569
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 1
O17
 72
hr
 1311 5294 5128 1.0323 1.0326
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 2
O17
 72
hr
 1311 4700 5100 0.9216 0.9183
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 3
O17
 72
hr
 1311 4988 5010 0.9954 0.9953
MDA-MB-231 Ruxolitinib
0.37
uM
LJP5
 1
O16
 72
hr
 1311 5258 5128 1.0253 1.0255
MDA-MB-231 Ruxolitinib
0.37
uM
LJP5
 2
O16
 72
hr
 1311 4990 5100 0.9784 0.9779
MDA-MB-231 Ruxolitinib
0.37
uM
LJP5
 3
O16
 72
hr
 1311 5441 5010 1.0858 1.0870
MDA-MB-231 Ruxolitinib
1.11
uM
LJP5
 1
O15
 72
hr
 1311 5253 5128 1.0243 1.0246
MDA-MB-231 Ruxolitinib
1.11
uM
LJP5
 2
O15
 72
hr
 1311 4857 5100 0.9524 0.9508
MDA-MB-231 Ruxolitinib
1.11
uM
LJP5
 3
O15
 72
hr
 1311 5189 5010 1.0356 1.0365
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 1
O14
 72
hr
 1311 4947 5128 0.9646 0.9637
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 2
O14
 72
hr
 1311 4964 5100 0.9733 0.9726
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 3
O14
 72
hr
 1311 5050 5010 1.0078 1.0081
MDA-MB-231 Ruxolitinib
10
uM
LJP5
 1
O13
 72
hr
 1311 4457 5128 0.8691 0.8623
MDA-MB-231 Ruxolitinib
10
uM
LJP5
 2
O13
 72
hr
 1311 4155 5100 0.8147 0.8014