LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 TGX221
10
uM
LJP5
 1
H19
 72
hr
 1311 4581 5128 0.8933 0.8885
MDA-MB-231 TGX221
10
uM
LJP5
 2
H19
 72
hr
 1311 4656 5100 0.9129 0.9091
MDA-MB-231 TGX221
10
uM
LJP5
 3
H19
 72
hr
 1311 4552 5010 0.9084 0.9031
MDA-MB-231 GSK1059615
0.04
uM
LJP6
 1
C06
 72
hr
 1311 5079 4870 1.0429 1.0449
MDA-MB-231 GSK1059615
0.04
uM
LJP6
 2
C06
 72
hr
 1311 5345 4961 1.0773 1.0791
MDA-MB-231 GSK1059615
0.04
uM
LJP6
 3
C06
 72
hr
 1311 4977 4973 1.0006 1.0007
MDA-MB-231 GSK1059615
0.04
uM
LJP5
 1
E06
 72
hr
 1311 4987 5128 0.9724 0.9718
MDA-MB-231 GSK1059615
0.04
uM
LJP5
 2
E06
 72
hr
 1311 5382 5100 1.0553 1.0557
MDA-MB-231 GSK1059615
0.04
uM
LJP5
 3
E06
 72
hr
 1311 5033 5010 1.0044 1.0046
MDA-MB-231 GSK1059615
0.12
uM
LJP6
 1
C05
 72
hr
 1311 4790 4870 0.9835 0.9825
MDA-MB-231 GSK1059615
0.12
uM
LJP6
 2
C05
 72
hr
 1311 5113 4961 1.0305 1.0316
MDA-MB-231 GSK1059615
0.12
uM
LJP6
 3
C05
 72
hr
 1311 4720 4973 0.9490 0.9463
MDA-MB-231 GSK1059615
0.12
uM
LJP5
 1
E05
 72
hr
 1311 5215 5128 1.0169 1.0171
MDA-MB-231 GSK1059615
0.12
uM
LJP5
 2
E05
 72
hr
 1311 4867 5100 0.9543 0.9528
MDA-MB-231 GSK1059615
0.12
uM
LJP5
 3
E05
 72
hr
 1311 4813 5010 0.9605 0.9588
MDA-MB-231 GSK1059615
0.37
uM
LJP6
 1
C04
 72
hr
 1311 4714 4870 0.9679 0.9658
MDA-MB-231 GSK1059615
0.37
uM
LJP6
 2
C04
 72
hr
 1311 4967 4961 1.0011 1.0011
MDA-MB-231 GSK1059615
0.37
uM
LJP6
 3
C04
 72
hr
 1311 4982 4973 1.0017 1.0017
MDA-MB-231 GSK1059615
0.37
uM
LJP5
 1
E04
 72
hr
 1311 4751 5128 0.9264 0.9238
MDA-MB-231 GSK1059615
0.37
uM
LJP5
 2
E04
 72
hr
 1311 4912 5100 0.9631 0.9620
MDA-MB-231 GSK1059615
0.37
uM
LJP5
 3
E04
 72
hr
 1311 4829 5010 0.9637 0.9621
MDA-MB-231 GSK1059615
1.11
uM
LJP6
 1
C03
 72
hr
 1311 4052 4870 0.8320 0.8148
MDA-MB-231 GSK1059615
1.11
uM
LJP6
 2
C03
 72
hr
 1311 4265 4961 0.8596 0.8484
MDA-MB-231 GSK1059615
1.11
uM
LJP6
 3
C03
 72
hr
 1311 3678 4973 0.7395 0.7095
MDA-MB-231 GSK1059615
1.11
uM
LJP5
 1
E03
 72
hr
 1311 3616 5128 0.7051 0.6745