LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T Brivanib
1.11
uM
LJP5
 1
P15
 72
hr
 765 3029 3140 0.9645 0.9649
Hs 578T Brivanib
1.11
uM
LJP5
 2
P15
 72
hr
 765 2881 3151 0.9141 0.9140
Hs 578T Brivanib
1.11
uM
LJP5
 3
P15
 72
hr
 765 2995 3152 0.9501 0.9505
Hs 578T Brivanib
3.33
uM
LJP5
 1
P14
 72
hr
 765 2953 3140 0.9403 0.9405
Hs 578T Brivanib
3.33
uM
LJP5
 2
P14
 72
hr
 765 2881 3151 0.9141 0.9140
Hs 578T Brivanib
3.33
uM
LJP5
 3
P14
 72
hr
 765 2958 3152 0.9383 0.9386
Hs 578T Brivanib
10
uM
LJP5
 1
P13
 72
hr
 765 2670 3140 0.8502 0.8469
Hs 578T Brivanib
10
uM
LJP5
 2
P13
 72
hr
 765 2546 3151 0.8078 0.8016
Hs 578T Brivanib
10
uM
LJP5
 3
P13
 72
hr
 765 2634 3152 0.8356 0.8316
Hs 578T CHIR-99021
0.04
uM
LJP6
 1
P18
 72
hr
 765 3023 3143 0.9616 0.9619
Hs 578T CHIR-99021
0.04
uM
LJP6
 2
P18
 72
hr
 765 3007 3095 0.9714 0.9714
Hs 578T CHIR-99021
0.04
uM
LJP6
 3
P18
 72
hr
 765 3133 3066 1.0219 1.0217
Hs 578T CHIR-99021
0.12
uM
LJP6
 1
P17
 72
hr
 765 2869 3143 0.9126 0.9123
Hs 578T CHIR-99021
0.12
uM
LJP6
 2
P17
 72
hr
 765 3024 3095 0.9769 0.9769
Hs 578T CHIR-99021
0.12
uM
LJP6
 3
P17
 72
hr
 765 3052 3066 0.9954 0.9954
Hs 578T CHIR-99021
0.37
uM
LJP6
 1
P16
 72
hr
 765 2846 3143 0.9053 0.9047
Hs 578T CHIR-99021
0.37
uM
LJP6
 2
P16
 72
hr
 765 2991 3095 0.9662 0.9662
Hs 578T CHIR-99021
0.37
uM
LJP6
 3
P16
 72
hr
 765 3002 3066 0.9791 0.9790
Hs 578T CHIR-99021
1.11
uM
LJP6
 1
P15
 72
hr
 765 2506 3143 0.7971 0.7895
Hs 578T CHIR-99021
1.11
uM
LJP6
 2
P15
 72
hr
 765 2787 3095 0.9003 0.8985
Hs 578T CHIR-99021
1.11
uM
LJP6
 3
P15
 72
hr
 765 2749 3066 0.8966 0.8939
Hs 578T CHIR-99021
3.33
uM
LJP6
 1
P14
 72
hr
 765 2653 3143 0.8439 0.8402
Hs 578T CHIR-99021
3.33
uM
LJP6
 2
P14
 72
hr
 765 2814 3095 0.9090 0.9076
Hs 578T CHIR-99021
3.33
uM
LJP6
 3
P14
 72
hr
 765 2803 3066 0.9142 0.9124
Hs 578T CHIR-99021
10
uM
LJP6
 1
P13
 72
hr
 765 1443 3143 0.4590 0.3651