LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T CHIR-99021
10
uM
LJP6
 2
P13
 72
hr
 765 1606 3095 0.5188 0.4445
Hs 578T CHIR-99021
10
uM
LJP6
 3
P13
 72
hr
 765 1386 3066 0.4521 0.3454
Hs 578T Linifanib
0.04
uM
LJP6
 1
J12
 72
hr
 765 3086 3143 0.9816 0.9819
Hs 578T Linifanib
0.04
uM
LJP6
 2
J12
 72
hr
 765 3177 3095 1.0263 1.0259
Hs 578T Linifanib
0.04
uM
LJP6
 3
J12
 72
hr
 765 3049 3066 0.9945 0.9945
Hs 578T Linifanib
0.12
uM
LJP6
 1
J11
 72
hr
 765 2996 3143 0.9530 0.9533
Hs 578T Linifanib
0.12
uM
LJP6
 2
J11
 72
hr
 765 3187 3095 1.0295 1.0291
Hs 578T Linifanib
0.12
uM
LJP6
 3
J11
 72
hr
 765 2979 3066 0.9716 0.9715
Hs 578T Linifanib
0.37
uM
LJP6
 1
J10
 72
hr
 765 3078 3143 0.9791 0.9794
Hs 578T Linifanib
0.37
uM
LJP6
 2
J10
 72
hr
 765 3054 3095 0.9866 0.9866
Hs 578T Linifanib
0.37
uM
LJP6
 3
J10
 72
hr
 765 3040 3066 0.9915 0.9915
Hs 578T Linifanib
1.11
uM
LJP6
 1
J09
 72
hr
 765 3040 3143 0.9670 0.9673
Hs 578T Linifanib
1.11
uM
LJP6
 2
J09
 72
hr
 765 2902 3095 0.9375 0.9370
Hs 578T Linifanib
1.11
uM
LJP6
 3
J09
 72
hr
 765 2935 3066 0.9573 0.9569
Hs 578T Linifanib
3.33
uM
LJP6
 1
J08
 72
hr
 765 3072 3143 0.9772 0.9775
Hs 578T Linifanib
3.33
uM
LJP6
 2
J08
 72
hr
 765 2917 3095 0.9423 0.9419
Hs 578T Linifanib
3.33
uM
LJP6
 3
J08
 72
hr
 765 2886 3066 0.9413 0.9405
Hs 578T Linifanib
10
uM
LJP6
 1
J07
 72
hr
 765 2697 3143 0.8579 0.8552
Hs 578T Linifanib
10
uM
LJP6
 2
J07
 72
hr
 765 2538 3095 0.8199 0.8124
Hs 578T Linifanib
10
uM
LJP6
 3
J07
 72
hr
 765 2526 3066 0.8239 0.8156
Hs 578T PIK-93
0.04
uM
LJP5
 1
K18
 72
hr
 765 3139 3140 0.9996 0.9996
Hs 578T PIK-93
0.04
uM
LJP5
 2
K18
 72
hr
 765 3191 3151 1.0125 1.0122
Hs 578T PIK-93
0.04
uM
LJP5
 3
K18
 72
hr
 765 3171 3152 1.0059 1.0058
Hs 578T PIK-93
0.12
uM
LJP5
 1
K17
 72
hr
 765 3200 3140 1.0190 1.0186
Hs 578T PIK-93
0.12
uM
LJP5
 2
K17
 72
hr
 765 3162 3151 1.0033 1.0032