LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
Hs 578T GSK1059615
1.11
uM
LJP6
 3
C03
 72
hr
 765 1418 3066 0.4625 0.3609
Hs 578T GSK1059615
1.11
uM
LJP5
 1
E03
 72
hr
 765 1299 3140 0.4137 0.2968
Hs 578T GSK1059615
1.11
uM
LJP5
 2
E03
 72
hr
 765 1352 3151 0.4290 0.3215
Hs 578T GSK1059615
1.11
uM
LJP5
 3
E03
 72
hr
 765 1396 3152 0.4428 0.3423
Hs 578T GSK1059615
3.33
uM
LJP6
 1
C02
 72
hr
 765 1101 3143 0.3502 0.1955
Hs 578T GSK1059615
3.33
uM
LJP6
 2
C02
 72
hr
 765 1054 3095 0.3405 0.1722
Hs 578T GSK1059615
3.33
uM
LJP6
 3
C02
 72
hr
 765 930 3066 0.3033 0.1024
Hs 578T GSK1059615
3.33
uM
LJP5
 1
E02
 72
hr
 765 640 3140 0.2038 -0.0839
Hs 578T GSK1059615
3.33
uM
LJP5
 2
E02
 72
hr
 765 439 3151 0.1393 -0.2381
Hs 578T GSK1059615
3.33
uM
LJP5
 3
E02
 72
hr
 765 506 3152 0.1605 -0.1832
Hs 578T GSK1059615
10
uM
LJP6
 1
C01
 72
hr
 765 572 3143 0.1820 -0.1329
Hs 578T GSK1059615
10
uM
LJP6
 2
C01
 72
hr
 765 641 3095 0.2071 -0.0840
Hs 578T GSK1059615
10
uM
LJP6
 3
C01
 72
hr
 765 881 3066 0.2874 0.0730
Hs 578T GSK1059615
10
uM
LJP5
 1
E01
 72
hr
 765 530 3140 0.1688 -0.1649
Hs 578T GSK1059615
10
uM
LJP5
 2
E01
 72
hr
 765 709 3151 0.2250 -0.0366
Hs 578T GSK1059615
10
uM
LJP5
 3
E01
 72
hr
 765 532 3152 0.1688 -0.1629
Hs 578T Brivanib
0.04
uM
LJP5
 1
P18
 72
hr
 765 3061 3140 0.9747 0.9750
Hs 578T Brivanib
0.04
uM
LJP5
 2
P18
 72
hr
 765 3108 3151 0.9862 0.9864
Hs 578T Brivanib
0.04
uM
LJP5
 3
P18
 72
hr
 765 3002 3152 0.9523 0.9527
Hs 578T Brivanib
0.12
uM
LJP5
 1
P17
 72
hr
 765 3212 3140 1.0228 1.0223
Hs 578T Brivanib
0.12
uM
LJP5
 2
P17
 72
hr
 765 2994 3151 0.9500 0.9504
Hs 578T Brivanib
0.12
uM
LJP5
 3
P17
 72
hr
 765 2998 3152 0.9510 0.9514
Hs 578T Brivanib
0.37
uM
LJP5
 1
P16
 72
hr
 765 3194 3140 1.0171 1.0167
Hs 578T Brivanib
0.37
uM
LJP5
 2
P16
 72
hr
 765 3058 3151 0.9703 0.9707
Hs 578T Brivanib
0.37
uM
LJP5
 3
P16
 72
hr
 765 2956 3152 0.9377 0.9380