LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Brivanib
1.11
uM
LJP5
 3
P15
 72
hr
 1311 5116 5010 1.0210 1.0216
MDA-MB-231 Brivanib
3.33
uM
LJP5
 1
P14
 72
hr
 1311 5178 5128 1.0097 1.0098
MDA-MB-231 Brivanib
3.33
uM
LJP5
 2
P14
 72
hr
 1311 4745 5100 0.9304 0.9277
MDA-MB-231 Brivanib
3.33
uM
LJP5
 3
P14
 72
hr
 1311 5318 5010 1.0613 1.0625
MDA-MB-231 Brivanib
10
uM
LJP5
 1
P13
 72
hr
 1311 3997 5128 0.7794 0.7620
MDA-MB-231 Brivanib
10
uM
LJP5
 2
P13
 72
hr
 1311 3977 5100 0.7798 0.7615
MDA-MB-231 Brivanib
10
uM
LJP5
 3
P13
 72
hr
 1311 4103 5010 0.8188 0.8036
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 1
P18
 72
hr
 1311 4643 4870 0.9534 0.9501
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 2
P18
 72
hr
 1311 4599 4961 0.9269 0.9225
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 3
P18
 72
hr
 1311 4751 4973 0.9552 0.9529
MDA-MB-231 CHIR-99021
0.12
uM
LJP6
 1
P17
 72
hr
 1311 4120 4870 0.8460 0.8308
MDA-MB-231 CHIR-99021
0.12
uM
LJP6
 2
P17
 72
hr
 1311 4255 4961 0.8576 0.8461
MDA-MB-231 CHIR-99021
0.12
uM
LJP6
 3
P17
 72
hr
 1311 4428 4973 0.8903 0.8827
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 1
P16
 72
hr
 1311 4274 4870 0.8776 0.8667
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 2
P16
 72
hr
 1311 4065 4961 0.8193 0.8027
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 3
P16
 72
hr
 1311 4469 4973 0.8985 0.8917
MDA-MB-231 CHIR-99021
1.11
uM
LJP6
 1
P15
 72
hr
 1311 4423 4870 0.9082 0.9008
MDA-MB-231 CHIR-99021
1.11
uM
LJP6
 2
P15
 72
hr
 1311 4443 4961 0.8955 0.8882
MDA-MB-231 CHIR-99021
1.11
uM
LJP6
 3
P15
 72
hr
 1311 4487 4973 0.9021 0.8957
MDA-MB-231 CHIR-99021
3.33
uM
LJP6
 1
P14
 72
hr
 1311 4491 4870 0.9221 0.9161
MDA-MB-231 CHIR-99021
3.33
uM
LJP6
 2
P14
 72
hr
 1311 4068 4961 0.8199 0.8034
MDA-MB-231 CHIR-99021
3.33
uM
LJP6
 3
P14
 72
hr
 1311 4310 4973 0.8665 0.8564
MDA-MB-231 CHIR-99021
10
uM
LJP6
 1
P13
 72
hr
 1311 3839 4870 0.7883 0.7637
MDA-MB-231 CHIR-99021
10
uM
LJP6
 2
P13
 72
hr
 1311 3528 4961 0.7111 0.6744
MDA-MB-231 CHIR-99021
10
uM
LJP6
 3
P13
 72
hr
 1311 3802 4973 0.7644 0.7392