LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 GSK1059615
1.11
uM
LJP5
 2
E03
 72
hr
 1311 3678 5100 0.7212 0.6927
MDA-MB-231 GSK1059615
1.11
uM
LJP5
 3
E03
 72
hr
 1311 3519 5010 0.7023 0.6659
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 1
C02
 72
hr
 1311 3178 4870 0.6525 0.5961
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 2
C02
 72
hr
 1311 3318 4961 0.6687 0.6218
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 3
C02
 72
hr
 1311 2862 4973 0.5754 0.5004
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 1
E02
 72
hr
 1311 1916 5128 0.3736 0.2124
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 2
E02
 72
hr
 1311 1709 5100 0.3351 0.1446
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 3
E02
 72
hr
 1311 2117 5010 0.4225 0.2809
MDA-MB-231 GSK1059615
10
uM
LJP6
 1
C01
 72
hr
 1311 2157 4870 0.4429 0.3006
MDA-MB-231 GSK1059615
10
uM
LJP6
 2
C01
 72
hr
 1311 2183 4961 0.4400 0.3039
MDA-MB-231 GSK1059615
10
uM
LJP6
 3
C01
 72
hr
 1311 1854 4973 0.3728 0.1972
MDA-MB-231 GSK1059615
10
uM
LJP5
 1
E01
 72
hr
 1311 2786 5128 0.5433 0.4666
MDA-MB-231 GSK1059615
10
uM
LJP5
 2
E01
 72
hr
 1311 1752 5100 0.3435 0.1592
MDA-MB-231 GSK1059615
10
uM
LJP5
 3
E01
 72
hr
 1311 2045 5010 0.4081 0.2582
MDA-MB-231 Brivanib
0.04
uM
LJP5
 1
P18
 72
hr
 1311 5280 5128 1.0296 1.0298
MDA-MB-231 Brivanib
0.04
uM
LJP5
 2
P18
 72
hr
 1311 5012 5100 0.9828 0.9823
MDA-MB-231 Brivanib
0.04
uM
LJP5
 3
P18
 72
hr
 1311 5386 5010 1.0749 1.0761
MDA-MB-231 Brivanib
0.12
uM
LJP5
 1
P17
 72
hr
 1311 4966 5128 0.9683 0.9676
MDA-MB-231 Brivanib
0.12
uM
LJP5
 2
P17
 72
hr
 1311 4692 5100 0.9200 0.9167
MDA-MB-231 Brivanib
0.12
uM
LJP5
 3
P17
 72
hr
 1311 5184 5010 1.0346 1.0354
MDA-MB-231 Brivanib
0.37
uM
LJP5
 1
P16
 72
hr
 1311 5008 5128 0.9765 0.9760
MDA-MB-231 Brivanib
0.37
uM
LJP5
 2
P16
 72
hr
 1311 4679 5100 0.9175 0.9140
MDA-MB-231 Brivanib
0.37
uM
LJP5
 3
P16
 72
hr
 1311 5263 5010 1.0503 1.0514
MDA-MB-231 Brivanib
1.11
uM
LJP5
 1
P15
 72
hr
 1311 5226 5128 1.0190 1.0193
MDA-MB-231 Brivanib
1.11
uM
LJP5
 2
P15
 72
hr
 1311 4789 5100 0.9390 0.9368