LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
 1
H23
 72
hr
 1311 4298 4870 0.8825 0.8722
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
 2
H23
 72
hr
 1311 4417 4961 0.8902 0.8824
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
 3
H23
 72
hr
 1311 4627 4973 0.9303 0.9262
MDA-MB-231 GSK1904529A
0.37
uM
LJP6
 1
H22
 72
hr
 1311 4402 4870 0.9039 0.8960
MDA-MB-231 GSK1904529A
0.37
uM
LJP6
 2
H22
 72
hr
 1311 4116 4961 0.8296 0.8145
MDA-MB-231 GSK1904529A
0.37
uM
LJP6
 3
H22
 72
hr
 1311 4765 4973 0.9580 0.9559
MDA-MB-231 GSK1904529A
1.11
uM
LJP6
 1
H21
 72
hr
 1311 4452 4870 0.9141 0.9073
MDA-MB-231 GSK1904529A
1.11
uM
LJP6
 2
H21
 72
hr
 1311 4299 4961 0.8665 0.8561
MDA-MB-231 GSK1904529A
1.11
uM
LJP6
 3
H21
 72
hr
 1311 4716 4973 0.9482 0.9454
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 1
H20
 72
hr
 1311 4706 4870 0.9663 0.9641
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 2
H20
 72
hr
 1311 4685 4961 0.9442 0.9411
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 3
H20
 72
hr
 1311 4934 4973 0.9920 0.9917
MDA-MB-231 GSK1904529A
10
uM
LJP6
 1
H19
 72
hr
 1311 4547 4870 0.9336 0.9287
MDA-MB-231 GSK1904529A
10
uM
LJP6
 2
H19
 72
hr
 1311 4777 4961 0.9628 0.9609
MDA-MB-231 GSK1904529A
10
uM
LJP6
 3
H19
 72
hr
 1311 4270 4973 0.8585 0.8475
MDA-MB-231 Linsitinib
0.04
uM
LJP5
 1
O24
 72
hr
 1311 4515 5128 0.8804 0.8746
MDA-MB-231 Linsitinib
0.04
uM
LJP5
 2
O24
 72
hr
 1311 4001 5100 0.7845 0.7670
MDA-MB-231 Linsitinib
0.04
uM
LJP5
 3
O24
 72
hr
 1311 4421 5010 0.8823 0.8746
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 1
O23
 72
hr
 1311 4758 5128 0.9278 0.9252
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 2
O23
 72
hr
 1311 4648 5100 0.9114 0.9075
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 3
O23
 72
hr
 1311 4655 5010 0.9290 0.9252
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 1
O22
 72
hr
 1311 4814 5128 0.9387 0.9367
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 2
O22
 72
hr
 1311 4853 5100 0.9516 0.9500
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 3
O22
 72
hr
 1311 4925 5010 0.9829 0.9822
MDA-MB-231 Linsitinib
1.11
uM
LJP5
 1
O21
 72
hr
 1311 4788 5128 0.9336 0.9314