LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Luminespib
0.04
uM
LJP5
 2
H18
 72
hr
 1311 1075 5100 0.2108 -0.0966
MDA-MB-231 Luminespib
0.04
uM
LJP5
 3
H18
 72
hr
 1311 993 5010 0.1982 -0.1341
MDA-MB-231 Luminespib
0.12
uM
LJP5
 1
H17
 72
hr
 1311 969 5128 0.1890 -0.1427
MDA-MB-231 Luminespib
0.12
uM
LJP5
 2
H17
 72
hr
 1311 1039 5100 0.2037 -0.1122
MDA-MB-231 Luminespib
0.12
uM
LJP5
 3
H17
 72
hr
 1311 973 5010 0.1942 -0.1431
MDA-MB-231 Luminespib
0.37
uM
LJP5
 1
H16
 72
hr
 1311 998 5128 0.1946 -0.1297
MDA-MB-231 Luminespib
0.37
uM
LJP5
 2
H16
 72
hr
 1311 1014 5100 0.1988 -0.1231
MDA-MB-231 Luminespib
0.37
uM
LJP5
 3
H16
 72
hr
 1311 1058 5010 0.2111 -0.1052
MDA-MB-231 Luminespib
1.11
uM
LJP5
 1
H15
 72
hr
 1311 1042 5128 0.2032 -0.1104
MDA-MB-231 Luminespib
1.11
uM
LJP5
 2
H15
 72
hr
 1311 1020 5100 0.2000 -0.1205
MDA-MB-231 Luminespib
1.11
uM
LJP5
 3
H15
 72
hr
 1311 996 5010 0.1988 -0.1327
MDA-MB-231 Luminespib
3.33
uM
LJP5
 1
H14
 72
hr
 1311 1062 5128 0.2071 -0.1018
MDA-MB-231 Luminespib
3.33
uM
LJP5
 2
H14
 72
hr
 1311 1031 5100 0.2022 -0.1157
MDA-MB-231 Luminespib
3.33
uM
LJP5
 3
H14
 72
hr
 1311 1060 5010 0.2115 -0.1043
MDA-MB-231 Luminespib
10
uM
LJP5
 1
H13
 72
hr
 1311 990 5128 0.1930 -0.1333
MDA-MB-231 Luminespib
10
uM
LJP5
 2
H13
 72
hr
 1311 1028 5100 0.2016 -0.1170
MDA-MB-231 Luminespib
10
uM
LJP5
 3
H13
 72
hr
 1311 958 5010 0.1912 -0.1500
MDA-MB-231 AZD8330
0.04
uM
LJP5
 1
G24
 72
hr
 1311 1746 5128 0.3405 0.1565
MDA-MB-231 AZD8330
0.04
uM
LJP5
 2
G24
 72
hr
 1311 1584 5100 0.3106 0.1011
MDA-MB-231 AZD8330
0.04
uM
LJP5
 3
G24
 72
hr
 1311 1801 5010 0.3594 0.1782
MDA-MB-231 AZD8330
0.12
uM
LJP5
 1
G23
 72
hr
 1311 1445 5128 0.2818 0.0504
MDA-MB-231 AZD8330
0.12
uM
LJP5
 2
G23
 72
hr
 1311 1697 5100 0.3328 0.1405
MDA-MB-231 AZD8330
0.12
uM
LJP5
 3
G23
 72
hr
 1311 1557 5010 0.3107 0.0927
MDA-MB-231 AZD8330
0.37
uM
LJP5
 1
G22
 72
hr
 1311 1364 5128 0.2660 0.0201
MDA-MB-231 AZD8330
0.37
uM
LJP5
 2
G22
 72
hr
 1311 1593 5100 0.3124 0.1043