LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PF431396
0.04
uM
LJP5
 2
E12
 72
hr
 1311 4570 5100 0.8961 0.8911
MDA-MB-231 PF431396
0.04
uM
LJP5
 3
E12
 72
hr
 1311 4711 5010 0.9402 0.9372
MDA-MB-231 PF431396
0.12
uM
LJP5
 1
E11
 72
hr
 1311 3858 5128 0.7523 0.7306
MDA-MB-231 PF431396
0.12
uM
LJP5
 2
E11
 72
hr
 1311 4339 5100 0.8508 0.8417
MDA-MB-231 PF431396
0.12
uM
LJP5
 3
E11
 72
hr
 1311 4004 5010 0.7991 0.7809
MDA-MB-231 PF431396
0.37
uM
LJP5
 1
E10
 72
hr
 1311 3086 5128 0.6018 0.5449
MDA-MB-231 PF431396
0.37
uM
LJP5
 2
E10
 72
hr
 1311 3533 5100 0.6928 0.6583
MDA-MB-231 PF431396
0.37
uM
LJP5
 3
E10
 72
hr
 1311 3236 5010 0.6458 0.5952
MDA-MB-231 PF431396
1.11
uM
LJP5
 1
E09
 72
hr
 1311 1796 5128 0.3502 0.1732
MDA-MB-231 PF431396
1.11
uM
LJP5
 2
E09
 72
hr
 1311 2047 5100 0.4014 0.2550
MDA-MB-231 PF431396
1.11
uM
LJP5
 3
E09
 72
hr
 1311 1971 5010 0.3934 0.2344
MDA-MB-231 PF431396
3.33
uM
LJP5
 1
E08
 72
hr
 1311 1404 5128 0.2738 0.0352
MDA-MB-231 PF431396
3.33
uM
LJP5
 2
E08
 72
hr
 1311 1577 5100 0.3092 0.0986
MDA-MB-231 PF431396
3.33
uM
LJP5
 3
E08
 72
hr
 1311 1451 5010 0.2896 0.0536
MDA-MB-231 PF431396
10
uM
LJP5
 1
E07
 72
hr
 1311 964 5128 0.1880 -0.1449
MDA-MB-231 PF431396
10
uM
LJP5
 2
E07
 72
hr
 1311 891 5100 0.1747 -0.1792
MDA-MB-231 PF431396
10
uM
LJP5
 3
E07
 72
hr
 1311 853 5010 0.1702 -0.1995
MDA-MB-231 Celastrol
0.04
uM
LJP6
 1
G12
 72
hr
 1311 5150 4870 1.0574 1.0599
MDA-MB-231 Celastrol
0.04
uM
LJP6
 2
G12
 72
hr
 1311 5197 4961 1.0474 1.0489
MDA-MB-231 Celastrol
0.04
uM
LJP6
 3
G12
 72
hr
 1311 5076 4973 1.0206 1.0213
MDA-MB-231 Celastrol
0.12
uM
LJP6
 1
G11
 72
hr
 1311 4894 4870 1.0049 1.0052
MDA-MB-231 Celastrol
0.12
uM
LJP6
 2
G11
 72
hr
 1311 4924 4961 0.9924 0.9921
MDA-MB-231 Celastrol
0.12
uM
LJP6
 3
G11
 72
hr
 1311 5123 4973 1.0300 1.0310
MDA-MB-231 Celastrol
0.37
uM
LJP6
 1
G10
 72
hr
 1311 4122 4870 0.8464 0.8313
MDA-MB-231 Celastrol
0.37
uM
LJP6
 2
G10
 72
hr
 1311 4466 4961 0.9001 0.8933