LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 PF477736
3.33
uM
LJP5
 1
J20
 72
hr
 1311 3050 5128 0.5947 0.5357
MDA-MB-231 PF477736
3.33
uM
LJP5
 2
J20
 72
hr
 1311 3035 5100 0.5951 0.5345
MDA-MB-231 PF477736
3.33
uM
LJP5
 3
J20
 72
hr
 1311 2975 5010 0.5937 0.5273
MDA-MB-231 PF477736
10
uM
LJP5
 1
J19
 72
hr
 1311 1313 5128 0.2560 0.0005
MDA-MB-231 PF477736
10
uM
LJP5
 2
J19
 72
hr
 1311 1300 5100 0.2549 -0.0046
MDA-MB-231 PF477736
10
uM
LJP5
 3
J19
 72
hr
 1311 1344 5010 0.2682 0.0127
MDA-MB-231 LDN-193189
0.04
uM
LJP5
 1
G06
 72
hr
 1311 4894 5128 0.9543 0.9530
MDA-MB-231 LDN-193189
0.04
uM
LJP5
 2
G06
 72
hr
 1311 4750 5100 0.9314 0.9287
MDA-MB-231 LDN-193189
0.04
uM
LJP5
 3
G06
 72
hr
 1311 4963 5010 0.9905 0.9901
MDA-MB-231 LDN-193189
0.12
uM
LJP5
 1
G05
 72
hr
 1311 4755 5128 0.9272 0.9246
MDA-MB-231 LDN-193189
0.12
uM
LJP5
 2
G05
 72
hr
 1311 4289 5100 0.8410 0.8308
MDA-MB-231 LDN-193189
0.12
uM
LJP5
 3
G05
 72
hr
 1311 4684 5010 0.9348 0.9314
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 1
G04
 72
hr
 1311 4783 5128 0.9327 0.9304
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 2
G04
 72
hr
 1311 4559 5100 0.8939 0.8887
MDA-MB-231 LDN-193189
0.37
uM
LJP5
 3
G04
 72
hr
 1311 4528 5010 0.9036 0.8979
MDA-MB-231 LDN-193189
1.11
uM
LJP5
 1
G03
 72
hr
 1311 4299 5128 0.8383 0.8285
MDA-MB-231 LDN-193189
1.11
uM
LJP5
 2
G03
 72
hr
 1311 3903 5100 0.7653 0.7447
MDA-MB-231 LDN-193189
1.11
uM
LJP5
 3
G03
 72
hr
 1311 4003 5010 0.7989 0.7807
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 1
G02
 72
hr
 1311 2719 5128 0.5302 0.4486
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 2
G02
 72
hr
 1311 2285 5100 0.4480 0.3275
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 3
G02
 72
hr
 1311 2585 5010 0.5159 0.4203
MDA-MB-231 LDN-193189
10
uM
LJP5
 1
G01
 72
hr
 1311 859 5128 0.1675 -0.1936
MDA-MB-231 LDN-193189
10
uM
LJP5
 2
G01
 72
hr
 1311 597 5100 0.1171 -0.3309
MDA-MB-231 LDN-193189
10
uM
LJP5
 3
G01
 72
hr
 1311 468 5010 0.0934 -0.4132
MDA-MB-231 PF431396
0.04
uM
LJP5
 1
E12
 72
hr
 1311 4509 5128 0.8792 0.8733