LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 WZ3105
3.33
uM
LJP5
 3
D20
 72
hr
 1311 800 5010 0.1597 -0.2257
MDA-MB-231 WZ3105
10
uM
LJP5
 1
D19
 72
hr
 1311 983 5128 0.1917 -0.1364
MDA-MB-231 WZ3105
10
uM
LJP5
 2
D19
 72
hr
 1311 1079 5100 0.2116 -0.0949
MDA-MB-231 WZ3105
10
uM
LJP5
 3
D19
 72
hr
 1311 1019 5010 0.2034 -0.1224
MDA-MB-231 XMD11-50
0.04
uM
LJP6
 1
P12
 72
hr
 1311 4668 4870 0.9585 0.9557
MDA-MB-231 XMD11-50
0.04
uM
LJP6
 2
P12
 72
hr
 1311 4497 4961 0.9064 0.9001
MDA-MB-231 XMD11-50
0.04
uM
LJP6
 3
P12
 72
hr
 1311 4991 4973 1.0035 1.0036
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 1
P11
 72
hr
 1311 4576 4870 0.9396 0.9352
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 2
P11
 72
hr
 1311 4251 4961 0.8568 0.8452
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 3
P11
 72
hr
 1311 4751 4973 0.9552 0.9529
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 1
P10
 72
hr
 1311 3686 4870 0.7569 0.7262
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 2
P10
 72
hr
 1311 3409 4961 0.6871 0.6448
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 3
P10
 72
hr
 1311 3755 4973 0.7550 0.7280
MDA-MB-231 XMD11-50
1.11
uM
LJP6
 1
P09
 72
hr
 1311 2641 4870 0.5423 0.4474
MDA-MB-231 XMD11-50
1.11
uM
LJP6
 2
P09
 72
hr
 1311 2474 4961 0.4986 0.3918
MDA-MB-231 XMD11-50
1.11
uM
LJP6
 3
P09
 72
hr
 1311 2726 4973 0.5481 0.4629
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 1
P08
 72
hr
 1311 1846 4870 0.3790 0.1979
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 2
P08
 72
hr
 1311 1850 4961 0.3729 0.1962
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 3
P08
 72
hr
 1311 2019 4973 0.4059 0.2514
MDA-MB-231 XMD11-50
10
uM
LJP6
 1
P07
 72
hr
 1311 1355 4870 0.2782 0.0173
MDA-MB-231 XMD11-50
10
uM
LJP6
 2
P07
 72
hr
 1311 1249 4961 0.2517 -0.0252
MDA-MB-231 XMD11-50
10
uM
LJP6
 3
P07
 72
hr
 1311 1499 4973 0.3014 0.0719
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 1
P24
 72
hr
 1311 3724 4870 0.7647 0.7356
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 2
P24
 72
hr
 1311 3936 4961 0.7933 0.7727
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 3
P24
 72
hr
 1311 3785 4973 0.7610 0.7352