LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
 2
J22
 72
hr
 1311 4613 4961 0.9297 0.9255
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
 3
J22
 72
hr
 1311 4521 4973 0.9090 0.9032
MDA-MB-231 WZ-4-145
1.11
uM
LJP6
 1
J21
 72
hr
 1311 4262 4870 0.8751 0.8639
MDA-MB-231 WZ-4-145
1.11
uM
LJP6
 2
J21
 72
hr
 1311 4264 4961 0.8594 0.8482
MDA-MB-231 WZ-4-145
1.11
uM
LJP6
 3
J21
 72
hr
 1311 4277 4973 0.8599 0.8490
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 1
J20
 72
hr
 1311 3886 4870 0.7979 0.7751
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 2
J20
 72
hr
 1311 4108 4961 0.8280 0.8126
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 3
J20
 72
hr
 1311 4093 4973 0.8229 0.8072
MDA-MB-231 WZ-4-145
10
uM
LJP6
 1
J19
 72
hr
 1311 1582 4870 0.3248 0.1041
MDA-MB-231 WZ-4-145
10
uM
LJP6
 2
J19
 72
hr
 1311 1682 4961 0.3390 0.1383
MDA-MB-231 WZ-4-145
10
uM
LJP6
 3
J19
 72
hr
 1311 1375 4973 0.2765 0.0248
MDA-MB-231 WZ3105
0.04
uM
LJP5
 1
D24
 72
hr
 1311 871 5128 0.1698 -0.1879
MDA-MB-231 WZ3105
0.04
uM
LJP5
 2
D24
 72
hr
 1311 782 5100 0.1533 -0.2321
MDA-MB-231 WZ3105
0.04
uM
LJP5
 3
D24
 72
hr
 1311 934 5010 0.1864 -0.1611
MDA-MB-231 WZ3105
0.12
uM
LJP5
 1
D23
 72
hr
 1311 828 5128 0.1615 -0.2086
MDA-MB-231 WZ3105
0.12
uM
LJP5
 2
D23
 72
hr
 1311 826 5100 0.1620 -0.2103
MDA-MB-231 WZ3105
0.12
uM
LJP5
 3
D23
 72
hr
 1311 840 5010 0.1676 -0.2059
MDA-MB-231 WZ3105
0.37
uM
LJP5
 1
D22
 72
hr
 1311 792 5128 0.1544 -0.2262
MDA-MB-231 WZ3105
0.37
uM
LJP5
 2
D22
 72
hr
 1311 771 5100 0.1512 -0.2376
MDA-MB-231 WZ3105
0.37
uM
LJP5
 3
D22
 72
hr
 1311 860 5010 0.1716 -0.1961
MDA-MB-231 WZ3105
1.11
uM
LJP5
 1
D21
 72
hr
 1311 862 5128 0.1681 -0.1922
MDA-MB-231 WZ3105
1.11
uM
LJP5
 2
D21
 72
hr
 1311 781 5100 0.1531 -0.2326
MDA-MB-231 WZ3105
1.11
uM
LJP5
 3
D21
 72
hr
 1311 853 5010 0.1702 -0.1995
MDA-MB-231 WZ3105
3.33
uM
LJP5
 1
D20
 72
hr
 1311 862 5128 0.1681 -0.1922
MDA-MB-231 WZ3105
3.33
uM
LJP5
 2
D20
 72
hr
 1311 792 5100 0.1553 -0.2271