LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MDA-MB-231 Ruxolitinib
10
uM
LJP5
 3
O13
 72
hr
 1311 4523 5010 0.9026 0.8968
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 1
P12
 72
hr
 1311 5022 5128 0.9793 0.9788
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 2
P12
 72
hr
 1311 4166 5100 0.8169 0.8038
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 3
P12
 72
hr
 1311 4810 5010 0.9599 0.9581
MDA-MB-231 Momelotinib
0.12
uM
LJP5
 1
P11
 72
hr
 1311 4454 5128 0.8685 0.8617
MDA-MB-231 Momelotinib
0.12
uM
LJP5
 2
P11
 72
hr
 1311 3949 5100 0.7743 0.7552
MDA-MB-231 Momelotinib
0.12
uM
LJP5
 3
P11
 72
hr
 1311 4493 5010 0.8967 0.8903
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 1
P10
 72
hr
 1311 3947 5128 0.7696 0.7507
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 2
P10
 72
hr
 1311 3519 5100 0.6900 0.6549
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 3
P10
 72
hr
 1311 3835 5010 0.7653 0.7417
MDA-MB-231 Momelotinib
1.11
uM
LJP5
 1
P09
 72
hr
 1311 3543 5128 0.6909 0.6572
MDA-MB-231 Momelotinib
1.11
uM
LJP5
 2
P09
 72
hr
 1311 3194 5100 0.6263 0.5750
MDA-MB-231 Momelotinib
1.11
uM
LJP5
 3
P09
 72
hr
 1311 3569 5010 0.7123 0.6781
MDA-MB-231 Momelotinib
3.33
uM
LJP5
 1
P08
 72
hr
 1311 2993 5128 0.5836 0.5210
MDA-MB-231 Momelotinib
3.33
uM
LJP5
 2
P08
 72
hr
 1311 2724 5100 0.5341 0.4521
MDA-MB-231 Momelotinib
3.33
uM
LJP5
 3
P08
 72
hr
 1311 2911 5010 0.5809 0.5102
MDA-MB-231 Momelotinib
10
uM
LJP5
 1
P07
 72
hr
 1311 1210 5128 0.2359 -0.0402
MDA-MB-231 Momelotinib
10
uM
LJP5
 2
P07
 72
hr
 1311 1209 5100 0.2371 -0.0408
MDA-MB-231 Momelotinib
10
uM
LJP5
 3
P07
 72
hr
 1311 1212 5010 0.2419 -0.0401
MDA-MB-231 Fedratinib
0.04
uM
LJP5
 1
L06
 72
hr
 1311 5183 5128 1.0107 1.0108
MDA-MB-231 Fedratinib
0.04
uM
LJP5
 2
L06
 72
hr
 1311 4950 5100 0.9706 0.9698
MDA-MB-231 Fedratinib
0.04
uM
LJP5
 3
L06
 72
hr
 1311 5250 5010 1.0477 1.0488
MDA-MB-231 Fedratinib
0.12
uM
LJP5
 1
L05
 72
hr
 1311 5312 5128 1.0358 1.0361
MDA-MB-231 Fedratinib
0.12
uM
LJP5
 2
L05
 72
hr
 1311 4575 5100 0.8971 0.8921
MDA-MB-231 Fedratinib
0.12
uM
LJP5
 3
L05
 72
hr
 1311 4687 5010 0.9354 0.9321