LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Geldanamycin | 10 | uM | LJP6 | 1 | O01 | 72 | hr | 1235 | 479 | 3974 | 0.1205 | -0.4300 |
| MCF 10A | Alvocidib | 3.33 | uM | LJP6 | 3 | A14 | 72 | hr | 513 | 480 | 10494 | 0.0457 | -0.0153 |
| MCF 10A | AZD8330 | 0.04 | uM | LJP5 | 3 | G24 | 72 | hr | 513 | 481 | 10483 | 0.0459 | -0.0149 |
| MDA-MB-231 | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 868 | 481 | 3429 | 0.1402 | -0.2576 |
| MCF 10A | Luminespib | 3.33 | uM | LJP5 | 3 | H14 | 72 | hr | 513 | 482 | 10483 | 0.0460 | -0.0144 |
| MCF 10A | Luminespib | 3.33 | uM | LJP5 | 1 | H14 | 72 | hr | 513 | 482 | 10254 | 0.0470 | -0.0145 |
| MCF 10A | Buparlisib | 3.33 | uM | LJP5 | 3 | H02 | 72 | hr | 513 | 483 | 10483 | 0.0461 | -0.0139 |
| MCF7 | Geldanamycin | 10 | uM | LJP5 | 2 | O01 | 72 | hr | 1235 | 483 | 4356 | 0.1109 | -0.4034 |
| MDA-MB-231 | Dasatinib | 0.37 | uM | LJP6 | 3 | I04 | 72 | hr | 868 | 484 | 3587 | 0.1349 | -0.2483 |
| MCF 10A | SNS-032 | 10 | uM | LJP6 | 3 | H13 | 72 | hr | 513 | 484 | 10494 | 0.0461 | -0.0134 |
| MCF 10A | SNS-032 | 1.11 | uM | LJP6 | 3 | H15 | 72 | hr | 513 | 485 | 10494 | 0.0462 | -0.0130 |
| MDA-MB-231 | CGP60474 | 3.33 | uM | LJP6 | 1 | G02 | 72 | hr | 868 | 486 | 3429 | 0.1417 | -0.2537 |
| MCF7 | SNS-032 | 0.37 | uM | LJP6 | 1 | H16 | 72 | hr | 1235 | 486 | 3974 | 0.1223 | -0.4250 |
| MCF 10A | AZD8330 | 0.12 | uM | LJP5 | 2 | G23 | 72 | hr | 513 | 487 | 10349 | 0.0471 | -0.0121 |
| MDA-MB-231 | Dasatinib | 1.11 | uM | LJP5 | 2 | D03 | 72 | hr | 868 | 488 | 3505 | 0.1392 | -0.2488 |
| MDA-MB-231 | Dasatinib | 3.33 | uM | LJP5 | 1 | D02 | 72 | hr | 868 | 488 | 3286 | 0.1485 | -0.2591 |
| MCF 10A | Afatinib | 3.33 | uM | LJP6 | 1 | G20 | 72 | hr | 513 | 489 | 10537 | 0.0464 | -0.0111 |
| MDA-MB-231 | Dasatinib | 1.11 | uM | LJP5 | 3 | D03 | 72 | hr | 868 | 491 | 3440 | 0.1427 | -0.2494 |
| MCF 10A | CGP60474 | 10 | uM | LJP5 | 1 | F01 | 72 | hr | 513 | 491 | 10254 | 0.0479 | -0.0103 |
| MCF 10A | PD0325901 | 10 | uM | LJP5 | 3 | C01 | 72 | hr | 513 | 492 | 10483 | 0.0469 | -0.0097 |
| MCF 10A | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 513 | 492 | 10494 | 0.0469 | -0.0097 |
| MCF 10A | Foretinib | 10 | uM | LJP5 | 3 | H07 | 72 | hr | 513 | 493 | 10483 | 0.0470 | -0.0093 |
| MCF 10A | AZD8330 | 0.04 | uM | LJP5 | 2 | G24 | 72 | hr | 513 | 493 | 10349 | 0.0476 | -0.0093 |
| MCF 10A | Torin2 | 0.37 | uM | LJP5 | 2 | I22 | 72 | hr | 513 | 494 | 10349 | 0.0477 | -0.0088 |
| MCF 10A | Luminespib | 1.11 | uM | LJP5 | 3 | H15 | 72 | hr | 513 | 494 | 10483 | 0.0471 | -0.0088 |