LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | AZD8055 | 10 | uM | LJP6 | 1 | A07 | 72 | hr | 513 | 887 | 10537 | 0.0842 | 0.1337 |
| MCF 10A | Sorafenib | 3.33 | uM | LJP6 | 1 | B08 | 72 | hr | 513 | 9781 | 10537 | 0.9282 | 0.9661 |
| MCF 10A | AZD8055 | 0.04 | uM | LJP6 | 1 | A12 | 72 | hr | 513 | 2495 | 10537 | 0.2368 | 0.4372 |
| MCF 10A | AZD8055 | 3.33 | uM | LJP6 | 1 | A08 | 72 | hr | 513 | 1133 | 10537 | 0.1075 | 0.1991 |
| MCF 10A | Sorafenib | 0.12 | uM | LJP6 | 1 | B11 | 72 | hr | 513 | 10248 | 10537 | 0.9725 | 0.9872 |
| MCF 10A | Sorafenib | 1.11 | uM | LJP6 | 1 | B09 | 72 | hr | 513 | 9758 | 10537 | 0.9260 | 0.9650 |
| MCF 10A | AZD7762 | 1.11 | uM | LJP6 | 1 | L03 | 72 | hr | 513 | 1939 | 10537 | 0.1840 | 0.3564 |
| MCF 10A | AZD7762 | 10 | uM | LJP6 | 1 | L01 | 72 | hr | 513 | 352 | 10537 | 0.0334 | -0.0829 |
| MCF 10A | AZD8055 | 0.12 | uM | LJP6 | 1 | A11 | 72 | hr | 513 | 1395 | 10537 | 0.1324 | 0.2577 |
| MCF 10A | AZD8055 | 1.11 | uM | LJP6 | 1 | A09 | 72 | hr | 513 | 1065 | 10537 | 0.1011 | 0.1822 |
| MCF 10A | Sorafenib | 0.04 | uM | LJP6 | 1 | B12 | 72 | hr | 513 | 11484 | 10537 | 1.0898 | 1.0398 |
| MCF 10A | AZD7762 | 0.12 | uM | LJP6 | 1 | L05 | 72 | hr | 513 | 5240 | 10537 | 0.4973 | 0.7038 |
| MCF 10A | AT-7519 | 0.12 | uM | LJP6 | 1 | K05 | 72 | hr | 513 | 8639 | 10537 | 0.8198 | 0.9109 |
| MCF 10A | Sorafenib | 0.37 | uM | LJP6 | 1 | B10 | 72 | hr | 513 | 10331 | 10537 | 0.9804 | 0.9909 |
| MCF 10A | AT-7519 | 0.37 | uM | LJP6 | 1 | K04 | 72 | hr | 513 | 943 | 10537 | 0.0895 | 0.1497 |
| MCF 10A | AZD7762 | 0.04 | uM | LJP6 | 1 | L06 | 72 | hr | 513 | 7567 | 10537 | 0.7181 | 0.8537 |
| MCF 10A | AT-7519 | 1.11 | uM | LJP6 | 1 | K03 | 72 | hr | 513 | 841 | 10537 | 0.0798 | 0.1199 |
| MCF 10A | AZD7762 | 0.37 | uM | LJP6 | 1 | L04 | 72 | hr | 513 | 3877 | 10537 | 0.3679 | 0.5901 |
| MCF 10A | AZD7762 | 3.33 | uM | LJP6 | 1 | L02 | 72 | hr | 513 | 978 | 10537 | 0.0928 | 0.1593 |
| MCF 10A | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 513 | 615 | 10537 | 0.0584 | 0.0423 |
| MCF 10A | AZD8055 | 0.37 | uM | LJP6 | 1 | A10 | 72 | hr | 513 | 1309 | 10537 | 0.1242 | 0.2395 |
| MCF 10A | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 513 | 437 | 10537 | 0.0415 | -0.0363 |
| MCF 10A | AT-7519 | 0.04 | uM | LJP6 | 1 | K06 | 72 | hr | 513 | 9715 | 10537 | 0.9219 | 0.9630 |
| MCF 10A | Alvocidib | 0.04 | uM | LJP6 | 1 | A18 | 72 | hr | 513 | 1244 | 10537 | 0.1181 | 0.2251 |
| MCF 10A | Sorafenib | 10 | uM | LJP6 | 1 | B07 | 72 | hr | 513 | 5938 | 10537 | 0.5635 | 0.7534 |