LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | AZD8055 | 0.04 | uM | LJP6 | 3 | A12 | 72 | hr | 1235 | 1129 | 4126 | 0.2736 | -0.0504 |
| MCF7 | AZD8055 | 3.33 | uM | LJP6 | 3 | A08 | 72 | hr | 1235 | 1184 | 4126 | 0.2869 | -0.0241 |
| MCF7 | AZD7762 | 0.12 | uM | LJP6 | 3 | L05 | 72 | hr | 1235 | 1665 | 4126 | 0.4035 | 0.1871 |
| MCF7 | AZD7762 | 10 | uM | LJP6 | 3 | L01 | 72 | hr | 1235 | 773 | 4126 | 0.1873 | -0.2362 |
| MCF7 | AZD8055 | 0.37 | uM | LJP6 | 3 | A10 | 72 | hr | 1235 | 1235 | 4126 | 0.2993 | -0.0002 |
| MCF7 | AZD8055 | 1.11 | uM | LJP6 | 3 | A09 | 72 | hr | 1235 | 1251 | 4126 | 0.3032 | 0.0072 |
| MCF7 | AZD7762 | 0.04 | uM | LJP6 | 3 | L06 | 72 | hr | 1235 | 1833 | 4126 | 0.4442 | 0.2546 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 3 | J05 | 72 | hr | 1235 | 5017 | 4326 | 1.1596 | 1.1707 |
| MCF7 | AZD7762 | 0.37 | uM | LJP6 | 3 | L04 | 72 | hr | 1235 | 1467 | 4126 | 0.3555 | 0.1038 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 3 | J03 | 72 | hr | 1235 | 3740 | 4326 | 0.8645 | 0.8452 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 3 | K02 | 72 | hr | 1235 | 891 | 4126 | 0.2159 | -0.1712 |
| MCF7 | AZD8055 | 0.12 | uM | LJP6 | 3 | A11 | 72 | hr | 1235 | 1350 | 4126 | 0.3272 | 0.0523 |
| MCF7 | Seliciclib | 0.04 | uM | LJP5 | 3 | J06 | 72 | hr | 1235 | 4855 | 4326 | 1.1222 | 1.1316 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 3 | J02 | 72 | hr | 1235 | 3295 | 4326 | 0.7616 | 0.7204 |
| MCF7 | AT-7519 | 0.37 | uM | LJP6 | 3 | K04 | 72 | hr | 1235 | 804 | 4126 | 0.1948 | -0.2188 |
| MCF7 | AT-7519 | 10 | uM | LJP6 | 3 | K01 | 72 | hr | 1235 | 785 | 4126 | 0.1902 | -0.2294 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 3 | J01 | 72 | hr | 1235 | 697 | 4326 | 0.1611 | -0.2713 |
| MCF7 | Seliciclib | 0.37 | uM | LJP5 | 3 | J04 | 72 | hr | 1235 | 3984 | 4326 | 0.9209 | 0.9109 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 3 | K03 | 72 | hr | 1235 | 826 | 4126 | 0.2002 | -0.2066 |
| MCF7 | AT-7519 | 0.04 | uM | LJP6 | 3 | K06 | 72 | hr | 1235 | 3793 | 4126 | 0.9192 | 0.9055 |
| MCF7 | AZD7762 | 1.11 | uM | LJP6 | 3 | L03 | 72 | hr | 1235 | 1365 | 4126 | 0.3308 | 0.0590 |
| MCF7 | AZD7762 | 3.33 | uM | LJP6 | 3 | L02 | 72 | hr | 1235 | 1060 | 4126 | 0.2569 | -0.0842 |
| MCF7 | AT-7519 | 0.12 | uM | LJP6 | 3 | K05 | 72 | hr | 1235 | 1370 | 4126 | 0.3320 | 0.0612 |
| MCF7 | Sorafenib | 0.04 | uM | LJP6 | 3 | B12 | 72 | hr | 1235 | 3858 | 4126 | 0.9350 | 0.9242 |
| MCF7 | AZD8055 | 10 | uM | LJP6 | 3 | A07 | 72 | hr | 1235 | 1032 | 4126 | 0.2501 | -0.0982 |