LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Normalized Growth Rate Inhibition Value
MCF7 Sirolimus
0.04
uM
LJP6
 3
L18
 72
hr
 1235 2835 4126 0.6871 0.6119
MCF7 Sirolimus
0.12
uM
LJP6
 1
L17
 72
hr
 1235 2588 3974 0.6512 0.5507
MCF7 Sirolimus
0.12
uM
LJP6
 2
L17
 72
hr
 1235 2558 4070 0.6285 0.5267
MCF7 Sirolimus
0.12
uM
LJP6
 3
L17
 72
hr
 1235 2806 4126 0.6800 0.6024
MCF7 Sirolimus
0.37
uM
LJP6
 1
L16
 72
hr
 1235 2543 3974 0.6399 0.5346
MCF7 Sirolimus
0.37
uM
LJP6
 2
L16
 72
hr
 1235 2222 4070 0.5459 0.4067
MCF7 Sirolimus
0.37
uM
LJP6
 3
L16
 72
hr
 1235 2732 4126 0.6621 0.5780
MCF7 Sirolimus
1.11
uM
LJP6
 1
L15
 72
hr
 1235 2576 3974 0.6482 0.5464
MCF7 Sirolimus
1.11
uM
LJP6
 2
L15
 72
hr
 1235 2587 4070 0.6356 0.5368
MCF7 Sirolimus
1.11
uM
LJP6
 3
L15
 72
hr
 1235 2788 4126 0.6757 0.5965
MCF7 Sirolimus
3.33
uM
LJP6
 1
L14
 72
hr
 1235 2444 3974 0.6150 0.4989
MCF7 Sirolimus
3.33
uM
LJP6
 2
L14
 72
hr
 1235 2550 4070 0.6265 0.5239
MCF7 Sirolimus
3.33
uM
LJP6
 3
L14
 72
hr
 1235 2604 4126 0.6311 0.5351
MCF7 Sirolimus
10
uM
LJP6
 1
L13
 72
hr
 1235 2613 3974 0.6575 0.5596
MCF7 Sirolimus
10
uM
LJP6
 2
L13
 72
hr
 1235 2339 4070 0.5746 0.4493
MCF7 Sirolimus
10
uM
LJP6
 3
L13
 72
hr
 1235 2864 4126 0.6941 0.6214
MCF7 ZSTK474
0.04
uM
LJP6
 1
M18
 72
hr
 1235 3632 3974 0.9139 0.8960
MCF7 ZSTK474
0.04
uM
LJP6
 2
M18
 72
hr
 1235 3175 4070 0.7800 0.7311
MCF7 ZSTK474
0.04
uM
LJP6
 3
M18
 72
hr
 1235 3183 4126 0.7714 0.7228
MCF7 ZSTK474
0.12
uM
LJP6
 1
M17
 72
hr
 1235 2563 3974 0.6449 0.5418
MCF7 ZSTK474
0.12
uM
LJP6
 2
M17
 72
hr
 1235 1919 4070 0.4715 0.2918
MCF7 ZSTK474
0.12
uM
LJP6
 3
M17
 72
hr
 1235 2395 4126 0.5804 0.4630
MCF7 ZSTK474
0.37
uM
LJP6
 1
M16
 72
hr
 1235 1644 3974 0.4137 0.1847
MCF7 ZSTK474
0.37
uM
LJP6
 2
M16
 72
hr
 1235 1491 4070 0.3663 0.1155
MCF7 ZSTK474
0.37
uM
LJP6
 3
M16
 72
hr
 1235 1563 4126 0.3788 0.1448