LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | PHA-793887 | 0.04 | uM | LJP6 | 1 | E24 | 72 | hr | 1235 | 1248 | 3974 | 0.3140 | 0.0060 |
| MCF7 | PHA-793887 | 0.04 | uM | LJP6 | 2 | E24 | 72 | hr | 1235 | 1290 | 4070 | 0.3169 | 0.0255 |
| MCF7 | PHA-793887 | 0.04 | uM | LJP6 | 3 | E24 | 72 | hr | 1235 | 1396 | 4126 | 0.3383 | 0.0728 |
| MCF7 | PHA-793887 | 0.12 | uM | LJP6 | 1 | E23 | 72 | hr | 1235 | 1262 | 3974 | 0.3176 | 0.0127 |
| MCF7 | PHA-793887 | 0.12 | uM | LJP6 | 2 | E23 | 72 | hr | 1235 | 1401 | 4070 | 0.3442 | 0.0759 |
| MCF7 | PHA-793887 | 0.12 | uM | LJP6 | 3 | E23 | 72 | hr | 1235 | 1482 | 4126 | 0.3592 | 0.1103 |
| MCF7 | PHA-793887 | 0.37 | uM | LJP6 | 1 | E22 | 72 | hr | 1235 | 1065 | 3974 | 0.2680 | -0.0843 |
| MCF7 | PHA-793887 | 0.37 | uM | LJP6 | 2 | E22 | 72 | hr | 1235 | 1295 | 4070 | 0.3182 | 0.0278 |
| MCF7 | PHA-793887 | 0.37 | uM | LJP6 | 3 | E22 | 72 | hr | 1235 | 1290 | 4126 | 0.3126 | 0.0252 |
| MCF7 | PHA-793887 | 1.11 | uM | LJP6 | 1 | E21 | 72 | hr | 1235 | 1144 | 3974 | 0.2879 | -0.0446 |
| MCF7 | PHA-793887 | 1.11 | uM | LJP6 | 2 | E21 | 72 | hr | 1235 | 1198 | 4070 | 0.2943 | -0.0177 |
| MCF7 | PHA-793887 | 1.11 | uM | LJP6 | 3 | E21 | 72 | hr | 1235 | 1280 | 4126 | 0.3102 | 0.0206 |
| MCF7 | PHA-793887 | 3.33 | uM | LJP6 | 1 | E20 | 72 | hr | 1235 | 985 | 3974 | 0.2479 | -0.1257 |
| MCF7 | PHA-793887 | 3.33 | uM | LJP6 | 2 | E20 | 72 | hr | 1235 | 1183 | 4070 | 0.2906 | -0.0249 |
| MCF7 | PHA-793887 | 3.33 | uM | LJP6 | 3 | E20 | 72 | hr | 1235 | 1262 | 4126 | 0.3058 | 0.0123 |
| MCF7 | PHA-793887 | 10 | uM | LJP6 | 1 | E19 | 72 | hr | 1235 | 560 | 3974 | 0.1409 | -0.3746 |
| MCF7 | PHA-793887 | 10 | uM | LJP6 | 2 | E19 | 72 | hr | 1235 | 745 | 4070 | 0.1830 | -0.2547 |
| MCF7 | PHA-793887 | 10 | uM | LJP6 | 3 | E19 | 72 | hr | 1235 | 613 | 4126 | 0.1486 | -0.3315 |
| MCF7 | QL-X-138 | 0.04 | uM | LJP6 | 1 | F24 | 72 | hr | 1235 | 1398 | 3974 | 0.3518 | 0.0761 |
| MCF7 | QL-X-138 | 0.04 | uM | LJP6 | 2 | F24 | 72 | hr | 1235 | 1982 | 4070 | 0.4869 | 0.3163 |
| MCF7 | QL-X-138 | 0.04 | uM | LJP6 | 3 | F24 | 72 | hr | 1235 | 2064 | 4126 | 0.5002 | 0.3431 |
| MCF7 | QL-X-138 | 0.12 | uM | LJP6 | 1 | F23 | 72 | hr | 1235 | 1508 | 3974 | 0.3795 | 0.1256 |
| MCF7 | QL-X-138 | 0.12 | uM | LJP6 | 2 | F23 | 72 | hr | 1235 | 1667 | 4070 | 0.4096 | 0.1903 |
| MCF7 | QL-X-138 | 0.12 | uM | LJP6 | 3 | F23 | 72 | hr | 1235 | 1767 | 4126 | 0.4282 | 0.2284 |
| MCF7 | QL-X-138 | 0.37 | uM | LJP6 | 1 | F22 | 72 | hr | 1235 | 1792 | 3974 | 0.4509 | 0.2469 |