LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 2 | A23 | 72 | hr | 1235 | 2970 | 4356 | 0.6818 | 0.6201 |
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 3 | A23 | 72 | hr | 1235 | 3145 | 4326 | 0.7269 | 0.6766 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 1 | A22 | 72 | hr | 1235 | 2423 | 4119 | 0.5882 | 0.4736 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 2 | A22 | 72 | hr | 1235 | 2579 | 4356 | 0.5920 | 0.4990 |
| MCF7 | Crizotinib | 0.37 | uM | LJP5 | 3 | A22 | 72 | hr | 1235 | 2453 | 4326 | 0.5670 | 0.4613 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 1 | A21 | 72 | hr | 1235 | 1550 | 4119 | 0.3763 | 0.1395 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 2 | A21 | 72 | hr | 1235 | 1685 | 4356 | 0.3868 | 0.1862 |
| MCF7 | Crizotinib | 1.11 | uM | LJP5 | 3 | A21 | 72 | hr | 1235 | 1689 | 4326 | 0.3904 | 0.1888 |
| MCF7 | Crizotinib | 3.33 | uM | LJP5 | 1 | A20 | 72 | hr | 1235 | 1195 | 4119 | 0.2901 | -0.0189 |
| MCF7 | Crizotinib | 3.33 | uM | LJP5 | 2 | A20 | 72 | hr | 1235 | 1272 | 4356 | 0.2920 | 0.0162 |
| MCF7 | Crizotinib | 3.33 | uM | LJP5 | 3 | A20 | 72 | hr | 1235 | 1262 | 4326 | 0.2917 | 0.0119 |
| MCF7 | Crizotinib | 10 | uM | LJP5 | 1 | A19 | 72 | hr | 1235 | 666 | 4119 | 0.1617 | -0.2993 |
| MCF7 | Crizotinib | 10 | uM | LJP5 | 2 | A19 | 72 | hr | 1235 | 792 | 4356 | 0.1818 | -0.2169 |
| MCF7 | Crizotinib | 10 | uM | LJP5 | 3 | A19 | 72 | hr | 1235 | 792 | 4326 | 0.1831 | -0.2180 |
| MCF7 | BMS345541 | 0.04 | uM | LJP6 | 1 | D06 | 72 | hr | 1235 | 4308 | 3974 | 1.0840 | 1.0980 |
| MCF7 | BMS345541 | 0.04 | uM | LJP6 | 2 | D06 | 72 | hr | 1235 | 4392 | 4070 | 1.0790 | 1.0904 |
| MCF7 | BMS345541 | 0.04 | uM | LJP6 | 3 | D06 | 72 | hr | 1235 | 4748 | 4126 | 1.1507 | 1.1680 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 1 | D05 | 72 | hr | 1235 | 4176 | 3974 | 1.0508 | 1.0597 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 2 | D05 | 72 | hr | 1235 | 4265 | 4070 | 1.0478 | 1.0551 |
| MCF7 | BMS345541 | 0.12 | uM | LJP6 | 3 | D05 | 72 | hr | 1235 | 4480 | 4126 | 1.0857 | 1.0968 |
| MCF7 | BMS345541 | 0.37 | uM | LJP6 | 1 | D04 | 72 | hr | 1235 | 4172 | 3974 | 1.0498 | 1.0585 |
| MCF7 | BMS345541 | 0.37 | uM | LJP6 | 2 | D04 | 72 | hr | 1235 | 3071 | 4070 | 0.7545 | 0.6979 |
| MCF7 | BMS345541 | 0.37 | uM | LJP6 | 3 | D04 | 72 | hr | 1235 | 4056 | 4126 | 0.9830 | 0.9803 |
| MCF7 | BMS345541 | 1.11 | uM | LJP6 | 1 | D03 | 72 | hr | 1235 | 2353 | 3974 | 0.5921 | 0.4655 |
| MCF7 | BMS345541 | 1.11 | uM | LJP6 | 2 | D03 | 72 | hr | 1235 | 1840 | 4070 | 0.4521 | 0.2606 |