LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 8 of 15: Cell count and normalized growth rate inhibition values within biological replicate 1. - Dataset (ID:20245)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | CGP60474 | 10 | uM | LJP5 | 1 | F01 | 72 | hr | 1235 | 681 | 4119 | 0.1653 | -0.2902 |
| MCF7 | CGP60474 | 10 | uM | LJP5 | 2 | F01 | 72 | hr | 1235 | 619 | 4356 | 0.1421 | -0.3162 |
| MCF7 | CGP60474 | 10 | uM | LJP5 | 3 | F01 | 72 | hr | 1235 | 711 | 4326 | 0.1643 | -0.2633 |
| MCF7 | PD173074 | 0.04 | uM | LJP6 | 1 | I12 | 72 | hr | 1235 | 4556 | 3974 | 1.1464 | 1.1689 |
| MCF7 | PD173074 | 0.04 | uM | LJP6 | 2 | I12 | 72 | hr | 1235 | 4605 | 4070 | 1.1314 | 1.1488 |
| MCF7 | PD173074 | 0.04 | uM | LJP6 | 3 | I12 | 72 | hr | 1235 | 4376 | 4126 | 1.0605 | 1.0687 |
| MCF7 | PD173074 | 0.12 | uM | LJP6 | 1 | I11 | 72 | hr | 1235 | 4678 | 3974 | 1.1771 | 1.2031 |
| MCF7 | PD173074 | 0.12 | uM | LJP6 | 2 | I11 | 72 | hr | 1235 | 4185 | 4070 | 1.0282 | 1.0326 |
| MCF7 | PD173074 | 0.12 | uM | LJP6 | 3 | I11 | 72 | hr | 1235 | 4418 | 4126 | 1.0707 | 1.0801 |
| MCF7 | PD173074 | 0.37 | uM | LJP6 | 1 | I10 | 72 | hr | 1235 | 4888 | 3974 | 1.2300 | 1.2613 |
| MCF7 | PD173074 | 0.37 | uM | LJP6 | 2 | I10 | 72 | hr | 1235 | 4275 | 4070 | 1.0503 | 1.0579 |
| MCF7 | PD173074 | 0.37 | uM | LJP6 | 3 | I10 | 72 | hr | 1235 | 4355 | 4126 | 1.0554 | 1.0630 |
| MCF7 | PD173074 | 1.11 | uM | LJP6 | 1 | I09 | 72 | hr | 1235 | 4642 | 3974 | 1.1681 | 1.1931 |
| MCF7 | PD173074 | 1.11 | uM | LJP6 | 2 | I09 | 72 | hr | 1235 | 4466 | 4070 | 1.0972 | 1.1108 |
| MCF7 | PD173074 | 1.11 | uM | LJP6 | 3 | I09 | 72 | hr | 1235 | 4970 | 4126 | 1.2045 | 1.2257 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 1 | I08 | 72 | hr | 1235 | 4800 | 3974 | 1.2078 | 1.2370 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 2 | I08 | 72 | hr | 1235 | 4722 | 4070 | 1.1601 | 1.1803 |
| MCF7 | PD173074 | 3.33 | uM | LJP6 | 3 | I08 | 72 | hr | 1235 | 5000 | 4126 | 1.2117 | 1.2334 |
| MCF7 | PD173074 | 10 | uM | LJP6 | 1 | I07 | 72 | hr | 1235 | 3203 | 3974 | 0.8060 | 0.7598 |
| MCF7 | PD173074 | 10 | uM | LJP6 | 2 | I07 | 72 | hr | 1235 | 2874 | 4070 | 0.7061 | 0.6337 |
| MCF7 | PD173074 | 10 | uM | LJP6 | 3 | I07 | 72 | hr | 1235 | 3312 | 4126 | 0.8027 | 0.7626 |
| MCF7 | Crizotinib | 0.04 | uM | LJP5 | 1 | A24 | 72 | hr | 1235 | 3193 | 4119 | 0.7752 | 0.7273 |
| MCF7 | Crizotinib | 0.04 | uM | LJP5 | 2 | A24 | 72 | hr | 1235 | 3111 | 4356 | 0.7141 | 0.6619 |
| MCF7 | Crizotinib | 0.04 | uM | LJP5 | 3 | A24 | 72 | hr | 1235 | 3673 | 4326 | 0.8490 | 0.8269 |
| MCF7 | Crizotinib | 0.12 | uM | LJP5 | 1 | A23 | 72 | hr | 1235 | 3070 | 4119 | 0.7453 | 0.6887 |