High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 337 | 336 | | 436 | 1226 | 74.6 | 15.23 | 8.13 | 2.56 | 60 | 63 | 66 | 68 | 70 | 73 | 77 | 87 | 99 | 0.2047 | 251 | 1.186 | 32.02 | 11.05 | 1 | 0.1904 | 83 | 0.0637 | 1.09 | 3.210 | 0.6546 | 5802.3 | 471400 | 40100000 | 3560000000 | 0.4209 | 0.2111 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0159 | 0.0074 | 0.0349 | 0.0123 | 0.1111 | 0.0539 | 0.1714 | 0.1176 | 0.1270 | 0.1176 | 0.1302 | 0.1544 | 0.4095 | 0.5368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0069 | 0.0280 | 0.0115 | 0.0509 | 0.0413 | 0.0865 | 0.0894 | 0.0789 | 0.0642 | 0.0941 | 0.0917 | 0.6539 | 0.6950 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0128 | 0.1429 | 0.0641 | 0.2500 | 0.0897 | 0.2143 | 0.2821 | 0.1786 | 0.1282 | 0.1071 | 0.1154 | 0.0714 | 0.3077 | 0.0357 | 0.0134 | 0.0067 | 0.0000 | 0.0537 | 0.0872 | 0.1409 | 0.0940 | 0.1208 | 0.4832 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0165 | 10.44 | 4.481 | 0.3254 | 72.6 | 704.432 | 7374.94 | 83019.4 | 0.4958 | 0.1499 | 0.0199 | 0.0010 | 0.0634 | 0.0049 | 0.1793 | 0.0119 | 0.2500 | 0.0415 | 0.2591 | 0.0889 | 0.1612 | 0.1235 | 0.0562 | 0.2075 | 0.0091 | 0.3063 | 0.0018 | 0.2144 | 0.0011 | 0.0000 | 0.0103 | 0.0018 | 0.0411 | 0.0044 | 0.0959 | 0.0176 | 0.1610 | 0.0668 | 0.1826 | 0.0809 | 0.1724 | 0.1161 | 0.2226 | 0.2577 | 0.1130 | 0.4547 | 0.1204 | 0.2880 | 0.1821 | 0.2640 | 0.2006 | 0.1600 | 0.1728 | 0.1280 | 0.1512 | 0.0880 | 0.0895 | 0.0560 | 0.0525 | 0.0160 | 0.0278 | 0.0000 | 0.0031 | 0.0000 | 0.0118 | 0.0485 | 0.1132 | 0.1559 | 0.1529 | 0.1500 | 0.1853 | 0.1250 | 0.0574 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 305 | | 577 | 1224 | 107.4 | 19.71 | 5.63 | 1.94 | 82 | 89 | 96 | 101 | 108 | 113 | 118 | 125 | 133 | 0.2230 | 273 | 1.197 | 35.36 | 14.21 | 1 | 0.1664 | 96 | 0.0277 | 1.58 | 3.824 | 0.5880 | 11913.2 | 1360000 | 161000000 | 19400000000 | 0.3940 | 0.2372 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0051 | 0.0000 | 0.0304 | 0.0018 | 0.0658 | 0.0406 | 0.1392 | 0.0689 | 0.1342 | 0.0548 | 0.1519 | 0.0707 | 0.4709 | 0.7633 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0000 | 0.0000 | 0.0143 | 0.0017 | 0.0369 | 0.0399 | 0.0656 | 0.0624 | 0.0615 | 0.0295 | 0.0820 | 0.0503 | 0.7377 | 0.8163 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0968 | 0.6364 | 0.1290 | 0.1818 | 0.2796 | 0.0909 | 0.1075 | 0.0909 | 0.1398 | 0.0000 | 0.2473 | 0.0000 | 0.0034 | 0.0068 | 0.0169 | 0.0203 | 0.0811 | 0.0980 | 0.0743 | 0.0845 | 0.6149 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0263 | 7.62 | 3.939 | 0.3680 | 35.5 | 244.168 | 1810.28 | 14316.1 | 0.5714 | 0.1153 | 0.0047 | 0.0000 | 0.0712 | 0.0040 | 0.1377 | 0.0160 | 0.2389 | 0.0419 | 0.2358 | 0.1028 | 0.2294 | 0.1766 | 0.0585 | 0.2535 | 0.0190 | 0.2685 | 0.0047 | 0.1367 | 0.0000 | 0.0000 | 0.0154 | 0.0019 | 0.0475 | 0.0065 | 0.1342 | 0.0260 | 0.1853 | 0.0854 | 0.2601 | 0.1365 | 0.1936 | 0.2201 | 0.1211 | 0.2934 | 0.0428 | 0.2303 | 0.3190 | 0.5467 | 0.3667 | 0.3333 | 0.1571 | 0.1067 | 0.1238 | 0.0133 | 0.0286 | 0.0000 | 0.0048 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0280 | 0.1226 | 0.1559 | 0.1961 | 0.2259 | 0.1471 | 0.0753 | 0.0350 | 0.0140 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1049 | 621 | | 590 | 4448 | 85.8 | 21.32 | 144.11 | 133.60 | 56 | 64 | 73 | 81 | 87 | 93 | 99 | 106 | 114 | 0.1034 | 460 | 0.497 | 89.47 | 17.12 | 2 | 0.4254 | 251 | 0.0059 | 8.91 | 5.340 | 0.3127 | 7819.9 | 748619 | 74600000 | 7680000000 | 0.5406 | 0.1228 | 0.0066 | 0.0000 | 0.0197 | 0.0037 | 0.0656 | 0.0019 | 0.1016 | 0.0335 | 0.1311 | 0.0764 | 0.2557 | 0.1676 | 0.1213 | 0.0950 | 0.1279 | 0.1639 | 0.1705 | 0.4581 | 0.0000 | 0.0000 | 0.0023 | 0.0018 | 0.0023 | 0.0018 | 0.0227 | 0.0161 | 0.0975 | 0.0698 | 0.2245 | 0.1592 | 0.0998 | 0.0823 | 0.1678 | 0.1485 | 0.3832 | 0.5206 | 0.0000 | 0.0000 | 0.0074 | 0.0909 | 0.0662 | 0.1818 | 0.1103 | 0.2273 | 0.1838 | 0.3636 | 0.2721 | 0.0455 | 0.1176 | 0.0909 | 0.0809 | 0.0000 | 0.1618 | 0.0000 | 0.0032 | 0.0130 | 0.0260 | 0.0747 | 0.1494 | 0.1851 | 0.1071 | 0.1558 | 0.2857 | 25 | 39 | 55 | 74 | 98 | 130 | 170 | 228 | 340 | 0.0100 | 16.93 | 5.669 | 0.4305 | 38612.5 | 14500000 | 6620000000 | 3390000000000 | 0.5378 | 0.1265 | 0.0156 | 0.0023 | 0.0845 | 0.0068 | 0.1831 | 0.0288 | 0.1815 | 0.0788 | 0.1800 | 0.1455 | 0.1315 | 0.1856 | 0.0767 | 0.1667 | 0.0610 | 0.1439 | 0.0861 | 0.2417 | 0.0010 | 0.0013 | 0.0036 | 0.0025 | 0.0051 | 0.0033 | 0.0159 | 0.0134 | 0.0568 | 0.0473 | 0.0967 | 0.0854 | 0.0747 | 0.0703 | 0.0988 | 0.1000 | 0.6474 | 0.6766 | 0.0000 | 0.0037 | 0.0038 | 0.0019 | 0.0198 | 0.0131 | 0.0243 | 0.0411 | 0.0654 | 0.0626 | 0.1209 | 0.1280 | 0.0928 | 0.0888 | 0.1042 | 0.1271 | 0.5688 | 0.5336 | 0.0006 | 0.0000 | 0.0112 | 0.0262 | 0.0611 | 0.1185 | 0.0855 | 0.1017 | 0.5951 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 79 | 365 | | 355 | 368 | 98.5 | 34.30 | 743.33 | 441.89 | 53 | 66 | 81 | 90 | 95 | 105 | 117 | 132 | 143 | 0.3995 | 147 | 1.183 | 36.12 | 15.52 | 1 | 0.2817 | 100 | 0.0040 | 43.26 | 5.614 | 0.2000 | 10879.1 | 1310000 | 169000000 | 22900000000 | 0.3710 | 0.2410 | 0.0000 | 0.0000 | 0.0265 | 0.0000 | 0.1060 | 0.0041 | 0.0927 | 0.0122 | 0.1258 | 0.1306 | 0.2053 | 0.1796 | 0.1589 | 0.1469 | 0.1126 | 0.1429 | 0.1722 | 0.3837 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0159 | 0.0067 | 0.0556 | 0.0669 | 0.1032 | 0.0635 | 0.0635 | 0.0535 | 0.1111 | 0.0702 | 0.6468 | 0.7391 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0297 | 0.1111 | 0.0792 | 0.2037 | 0.1386 | 0.2037 | 0.2673 | 0.2037 | 0.1287 | 0.1296 | 0.1287 | 0.1111 | 0.2277 | 0.0370 | 0.0000 | 0.0060 | 0.0060 | 0.0539 | 0.1257 | 0.1796 | 0.0958 | 0.1796 | 0.3533 | 167 | 338 | 432 | 575 | 717 | 837 | 975 | 1120 | 1332 | 0.0029 | 177.01 | 5.867 | 0.1008 | 747281.0 | 884000000 | 1170000000000 | 1.66E+15 | 0.3788 | 0.2356 | 0.0116 | 0.0127 | 0.1744 | 0.0570 | 0.2209 | 0.0633 | 0.2326 | 0.1266 | 0.1512 | 0.2089 | 0.1279 | 0.1835 | 0.0814 | 0.1835 | 0.0000 | 0.0886 | 0.0000 | 0.0759 | 0.0000 | 0.0040 | 0.0230 | 0.0199 | 0.0230 | 0.0199 | 0.0829 | 0.0598 | 0.1429 | 0.1474 | 0.1060 | 0.1235 | 0.1567 | 0.1474 | 0.1751 | 0.1633 | 0.2903 | 0.3147 | 0.0000 | 0.0000 | 0.0076 | 0.0108 | 0.0458 | 0.0323 | 0.0458 | 0.0860 | 0.2061 | 0.2688 | 0.1756 | 0.2151 | 0.1374 | 0.1720 | 0.2443 | 0.1828 | 0.1374 | 0.0323 | 0.0058 | 0.0173 | 0.0405 | 0.0578 | 0.1214 | 0.1445 | 0.1792 | 0.1850 | 0.2486 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1017 | 554 | | 378 | 9755 | 70.8 | 9.18 | 6.27 | 2.35 | 58 | 62 | 65 | 69 | 72 | 74 | 76 | 79 | 82 | 0.0685 | 668 | 1.025 | 80.23 | 26.63 | 2 | 0.5556 | 210 | 0.0307 | 2.20 | 3.799 | 0.5317 | 5100.6 | 373029 | 27700000 | 2080000000 | 0.3766 | 0.2528 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0000 | 0.0121 | 0.0053 | 0.0725 | 0.0556 | 0.0816 | 0.0635 | 0.0816 | 0.0503 | 0.1178 | 0.0688 | 0.6284 | 0.7566 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0000 | 0.0116 | 0.0053 | 0.0607 | 0.0556 | 0.0665 | 0.0635 | 0.0520 | 0.0503 | 0.0838 | 0.0688 | 0.7197 | 0.7566 | 0.0667 | 0.0000 | 0.0000 | 0.0000 | 0.0667 | 0.0000 | 0.2667 | 0.0000 | 0.0000 | 0.0000 | 0.2667 | 0.0000 | 0.2000 | 0.0000 | 0.0000 | 0.0000 | 0.1333 | 0.0000 | 0.0000 | 0.0093 | 0.0139 | 0.0324 | 0.0694 | 0.0787 | 0.0972 | 0.1481 | 0.5509 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.2315 | 0.45 | 1.048 | 0.5873 | 44.8 | 356.698 | 3133.82 | 30121.9 | 0.5230 | 0.1563 | 0.0095 | 0.0016 | 0.0423 | 0.0054 | 0.1159 | 0.0156 | 0.1913 | 0.0399 | 0.2491 | 0.0756 | 0.2068 | 0.1496 | 0.1260 | 0.2580 | 0.0507 | 0.3008 | 0.0085 | 0.1535 | 0.0009 | 0.0000 | 0.0033 | 0.0003 | 0.0157 | 0.0022 | 0.0417 | 0.0102 | 0.0896 | 0.0267 | 0.1561 | 0.0434 | 0.2071 | 0.1072 | 0.2316 | 0.2692 | 0.2540 | 0.5409 | 0.0990 | 0.1881 | 0.1831 | 0.2085 | 0.1795 | 0.1599 | 0.1502 | 0.1178 | 0.1272 | 0.0944 | 0.0980 | 0.0655 | 0.0618 | 0.0505 | 0.0512 | 0.0589 | 0.0501 | 0.0565 | 0.0080 | 0.0313 | 0.0735 | 0.1349 | 0.1725 | 0.1695 | 0.1459 | 0.1396 | 0.1248 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1052 | 727 | | 435 | 10158 | 216.6 | 37.95 | 134.54 | 228.49 | 169 | 184 | 193 | 205 | 215 | 223 | 235 | 249 | 268 | 0.0475 | 483 | 1.039 | 156.49 | 50.48 | 1 | 0.9218 | 401 | 0.0052 | 14.90 | 5.415 | 0.3014 | 48369.5 | 11100000 | 2630000000 | 636000000000 | 0.4349 | 0.2080 | 0.0000 | 0.0000 | 0.0096 | 0.0000 | 0.0096 | 0.0000 | 0.0382 | 0.0047 | 0.1019 | 0.0606 | 0.1656 | 0.0629 | 0.1624 | 0.0606 | 0.1943 | 0.0956 | 0.3185 | 0.7156 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0186 | 0.0023 | 0.0849 | 0.0621 | 0.1088 | 0.0552 | 0.0928 | 0.0437 | 0.1432 | 0.0759 | 0.5517 | 0.7609 | 0.0000 | 0.1667 | 0.0000 | 0.0000 | 0.0635 | 0.1667 | 0.1905 | 0.3333 | 0.1429 | 0.3333 | 0.2540 | 0.0000 | 0.1270 | 0.0000 | 0.0635 | 0.0000 | 0.1587 | 0.0000 | 0.0000 | 0.0095 | 0.0237 | 0.0616 | 0.1754 | 0.1469 | 0.1280 | 0.1801 | 0.2749 | 5 | 7 | 8 | 9 | 11 | 16 | 98 | 264 | 495 | 0.1308 | 20.25 | 3.815 | 0.5357 | 70302.5 | 49000000 | 40900000000 | 40000000000000 | 0.5326 | 0.1283 | 0.0600 | 0.0028 | 0.2086 | 0.0308 | 0.2229 | 0.1413 | 0.2086 | 0.1636 | 0.1400 | 0.2070 | 0.0686 | 0.1930 | 0.0514 | 0.1035 | 0.0371 | 0.0867 | 0.0029 | 0.0713 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0037 | 0.0047 | 0.0269 | 0.0233 | 0.0561 | 0.0472 | 0.0326 | 0.0315 | 0.0668 | 0.0585 | 0.8136 | 0.8348 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0011 | 0.0020 | 0.0049 | 0.0053 | 0.0377 | 0.0422 | 0.0681 | 0.0763 | 0.0518 | 0.0666 | 0.0883 | 0.0849 | 0.7477 | 0.7223 | 0.0000 | 0.0000 | 0.0011 | 0.0029 | 0.0350 | 0.0622 | 0.0404 | 0.0733 | 0.7851 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 726 | 600 | | 3242 | 14311 | 499.5 | 83.43 | 217.74 | 192.04 | 394 | 426 | 450 | 470 | 493 | 518 | 547 | 576 | 612 | 0.0641 | 917 | 0.675 | 101.83 | 25.18 | 1 | 0.0999 | 324 | 0.0014 | 30.06 | 6.786 | 0.2232 | 256441.0 | 135000000 | 73000000000 | 40400000000000 | 0.4615 | 0.1909 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0029 | 0.0003 | 0.0094 | 0.0019 | 0.0476 | 0.0128 | 0.1034 | 0.0350 | 0.0932 | 0.0172 | 0.1211 | 0.0428 | 0.6215 | 0.8900 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0031 | 0.0015 | 0.0241 | 0.0115 | 0.0544 | 0.0319 | 0.0457 | 0.0124 | 0.0582 | 0.0254 | 0.8139 | 0.9170 | 0.0069 | 0.2000 | 0.0185 | 0.2000 | 0.0254 | 0.1333 | 0.0762 | 0.2667 | 0.1224 | 0.0667 | 0.2517 | 0.1333 | 0.1201 | 0.0000 | 0.1386 | 0.0000 | 0.2402 | 0.0000 | 0.0026 | 0.0013 | 0.0110 | 0.0272 | 0.0725 | 0.1146 | 0.0881 | 0.1075 | 0.5751 | 27 | 59 | 91 | 117 | 149 | 197 | 277 | 373 | 502 | 0.0056 | 39.72 | 6.385 | 0.3525 | 84287.2 | 43400000 | 26300000000 | 17700000000000 | 0.5008 | 0.1648 | 0.0367 | 0.0032 | 0.1371 | 0.0092 | 0.2234 | 0.0566 | 0.1856 | 0.1095 | 0.1607 | 0.1802 | 0.1201 | 0.1909 | 0.0615 | 0.1404 | 0.0434 | 0.1268 | 0.0316 | 0.1831 | 0.0010 | 0.0008 | 0.0021 | 0.0015 | 0.0046 | 0.0040 | 0.0193 | 0.0143 | 0.0618 | 0.0534 | 0.0900 | 0.0837 | 0.0683 | 0.0638 | 0.1015 | 0.0908 | 0.6515 | 0.6878 | 0.0004 | 0.0008 | 0.0007 | 0.0042 | 0.0048 | 0.0124 | 0.0253 | 0.0287 | 0.0830 | 0.0944 | 0.1247 | 0.1404 | 0.1000 | 0.1138 | 0.1419 | 0.1548 | 0.5192 | 0.4506 | 0.0006 | 0.0023 | 0.0015 | 0.0250 | 0.0581 | 0.1139 | 0.0806 | 0.1154 | 0.6027 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 584 | 956 | | 603 | 2463 | 406.2 | 49.35 | 106.45 | 171.74 | 341 | 360 | 374 | 391 | 405 | 421 | 434 | 449 | 475 | 0.1397 | 344 | 0.741 | 102.83 | 29.41 | 1 | 0.4809 | 290 | 0.0035 | 18.91 | 5.793 | 0.2498 | 167409.0 | 70000000 | 29700000000 | 12800000000000 | 0.3625 | 0.2807 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0037 | 0.0017 | 0.0608 | 0.0415 | 0.0958 | 0.0630 | 0.0608 | 0.0315 | 0.1105 | 0.0481 | 0.6648 | 0.8143 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0034 | 0.0017 | 0.0444 | 0.0415 | 0.0650 | 0.0630 | 0.0342 | 0.0315 | 0.0581 | 0.0481 | 0.7932 | 0.8143 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0952 | 0.0000 | 0.1190 | 0.0000 | 0.1905 | 0.0000 | 0.2381 | 0.0000 | 0.1429 | 0.0000 | 0.1190 | 0.0000 | 0.0952 | 0.0000 | 0.0000 | 0.0000 | 0.0101 | 0.0269 | 0.0842 | 0.1010 | 0.1010 | 0.1279 | 0.5488 | 8 | 10 | 11 | 13 | 15 | 30 | 107 | 188 | 310 | 0.1805 | 23.87 | 3.814 | 0.6487 | 40814.5 | 22400000 | 14400000000 | 10100000000000 | 0.5211 | 0.1245 | 0.0866 | 0.0122 | 0.0551 | 0.0528 | 0.1417 | 0.1098 | 0.2205 | 0.1138 | 0.1575 | 0.1301 | 0.1890 | 0.1707 | 0.0787 | 0.1220 | 0.0236 | 0.1260 | 0.0472 | 0.1626 | 0.0012 | 0.0000 | 0.0000 | 0.0047 | 0.0025 | 0.0070 | 0.0149 | 0.0117 | 0.0532 | 0.0493 | 0.0916 | 0.0880 | 0.0668 | 0.0563 | 0.0693 | 0.0599 | 0.7005 | 0.7230 | 0.0015 | 0.0017 | 0.0000 | 0.0033 | 0.0132 | 0.0132 | 0.0264 | 0.0281 | 0.0543 | 0.0677 | 0.1189 | 0.1254 | 0.0764 | 0.0858 | 0.0837 | 0.1073 | 0.6256 | 0.5677 | 0.0000 | 0.0013 | 0.0040 | 0.0148 | 0.0617 | 0.1074 | 0.0671 | 0.0832 | 0.6604 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 658 | 168 | | 403 | 1766 | 68.5 | 19.76 | 7.99 | 2.37 | 49 | 53 | 56 | 59 | 63 | 70 | 74 | 85 | 98 | 0.1750 | 309 | 1.167 | 34.83 | 13.34 | 1 | 0.2258 | 91 | 0.0533 | 1.76 | 3.525 | 0.6505 | 5083.4 | 408505 | 35400000 | 3290000000 | 0.4186 | 0.2106 | 0.0050 | 0.0000 | 0.0347 | 0.0029 | 0.1139 | 0.0233 | 0.1139 | 0.0437 | 0.1386 | 0.0962 | 0.1238 | 0.1895 | 0.1386 | 0.1137 | 0.1238 | 0.1429 | 0.2079 | 0.3878 | 0.0034 | 0.0000 | 0.0103 | 0.0000 | 0.0206 | 0.0052 | 0.0412 | 0.0129 | 0.1237 | 0.0722 | 0.1340 | 0.1727 | 0.0790 | 0.0851 | 0.0962 | 0.1134 | 0.4914 | 0.5387 | 0.0112 | 0.0000 | 0.0112 | 0.0000 | 0.0000 | 0.0667 | 0.1236 | 0.2444 | 0.1685 | 0.2222 | 0.2360 | 0.2667 | 0.0787 | 0.0222 | 0.1461 | 0.0667 | 0.2247 | 0.1111 | 0.0000 | 0.0000 | 0.0117 | 0.0526 | 0.1287 | 0.1988 | 0.0877 | 0.1345 | 0.3860 | 5 | 6 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 0.0170 | 10.27 | 4.413 | 0.3266 | 69.5 | 648.007 | 6410.02 | 66817.3 | 0.4806 | 0.1782 | 0.0225 | 0.0013 | 0.0688 | 0.0040 | 0.1865 | 0.0092 | 0.2678 | 0.0257 | 0.2240 | 0.0870 | 0.1502 | 0.1087 | 0.0601 | 0.1963 | 0.0138 | 0.3057 | 0.0063 | 0.2622 | 0.0049 | 0.0000 | 0.0154 | 0.0018 | 0.0561 | 0.0054 | 0.0829 | 0.0127 | 0.1488 | 0.0647 | 0.1715 | 0.0810 | 0.1837 | 0.0906 | 0.2179 | 0.2502 | 0.1187 | 0.4937 | 0.1230 | 0.3869 | 0.2181 | 0.2993 | 0.2645 | 0.1314 | 0.1763 | 0.1314 | 0.1137 | 0.0292 | 0.0650 | 0.0219 | 0.0232 | 0.0000 | 0.0139 | 0.0000 | 0.0023 | 0.0000 | 0.0089 | 0.0445 | 0.0870 | 0.1235 | 0.1966 | 0.2184 | 0.1601 | 0.1235 | 0.0375 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 656 | 535 | | 6091 | 20546 | 242.4 | 44.53 | 137.26 | 192.39 | 187 | 203 | 216 | 228 | 239 | 251 | 264 | 280 | 303 | 0.0476 | 979 | 1.098 | 86.73 | 30.00 | 1 | 0.0368 | 224 | 0.0009 | 51.40 | 7.200 | 0.1626 | 60738.6 | 15700000 | 4190000000 | 1150000000000 | 0.4279 | 0.2267 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0124 | 0.0005 | 0.0636 | 0.0142 | 0.1292 | 0.0326 | 0.1368 | 0.0323 | 0.1768 | 0.0541 | 0.4789 | 0.8663 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0008 | 0.0000 | 0.0040 | 0.0002 | 0.0280 | 0.0117 | 0.0548 | 0.0216 | 0.0579 | 0.0143 | 0.0777 | 0.0241 | 0.7764 | 0.9281 | 0.0078 | 0.0464 | 0.0056 | 0.0265 | 0.0468 | 0.1126 | 0.1158 | 0.2649 | 0.1815 | 0.2119 | 0.2305 | 0.1854 | 0.1236 | 0.0795 | 0.1336 | 0.0530 | 0.1548 | 0.0199 | 0.0003 | 0.0010 | 0.0075 | 0.0369 | 0.0799 | 0.1438 | 0.1237 | 0.1565 | 0.4503 | 10 | 11 | 13 | 16 | 25 | 62 | 149 | 281 | 445 | 0.1040 | 21.77 | 4.771 | 0.5558 | 55854.0 | 29600000 | 17800000000 | 11700000000000 | 0.5221 | 0.1170 | 0.0474 | 0.0028 | 0.1966 | 0.0109 | 0.3034 | 0.1095 | 0.1798 | 0.1664 | 0.1433 | 0.2227 | 0.0870 | 0.1986 | 0.0267 | 0.1227 | 0.0128 | 0.0858 | 0.0030 | 0.0806 | 0.0003 | 0.0003 | 0.0009 | 0.0003 | 0.0017 | 0.0020 | 0.0094 | 0.0084 | 0.0422 | 0.0385 | 0.0682 | 0.0630 | 0.0444 | 0.0432 | 0.0669 | 0.0635 | 0.7660 | 0.7808 | 0.0002 | 0.0002 | 0.0002 | 0.0009 | 0.0014 | 0.0024 | 0.0088 | 0.0122 | 0.0505 | 0.0500 | 0.0741 | 0.0794 | 0.0549 | 0.0568 | 0.0763 | 0.0835 | 0.7338 | 0.7146 | 0.0005 | 0.0006 | 0.0024 | 0.0080 | 0.0436 | 0.0706 | 0.0510 | 0.0733 | 0.7499 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 779 | 772 | | 630 | 2293 | 62.2 | 11.79 | 6.82 | 2.35 | 48 | 51 | 54 | 57 | 61 | 65 | 69 | 73 | 77 | 0.1522 | 349 | 0.662 | 34.06 | 7.21 | 2 | 0.1444 | 91 | 0.0668 | 0.76 | 2.979 | 0.7113 | 4008.3 | 267309 | 18400000 | 1310000000 | 0.4337 | 0.1967 | 0.0000 | 0.0000 | 0.0115 | 0.0000 | 0.0253 | 0.0016 | 0.0484 | 0.0081 | 0.1106 | 0.0520 | 0.1521 | 0.0846 | 0.1728 | 0.0618 | 0.2166 | 0.1317 | 0.2627 | 0.6602 | 0.0000 | 0.0000 | 0.0038 | 0.0000 | 0.0075 | 0.0016 | 0.0226 | 0.0048 | 0.0658 | 0.0476 | 0.0921 | 0.0778 | 0.0714 | 0.0429 | 0.1372 | 0.0984 | 0.5996 | 0.7270 | 0.0102 | 0.1333 | 0.0408 | 0.0000 | 0.0612 | 0.1333 | 0.1633 | 0.4000 | 0.1837 | 0.0000 | 0.2245 | 0.2667 | 0.1224 | 0.0000 | 0.1020 | 0.0000 | 0.0918 | 0.0667 | 0.0000 | 0.0000 | 0.0065 | 0.0647 | 0.0971 | 0.1100 | 0.1197 | 0.1553 | 0.4466 | 4 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 10 | 0.0239 | 6.69 | 4.216 | 0.3943 | 52.0 | 441.077 | 4128.92 | 42300.9 | 0.5603 | 0.1272 | 0.0098 | 0.0035 | 0.0446 | 0.0081 | 0.1223 | 0.0190 | 0.1982 | 0.0432 | 0.2580 | 0.0876 | 0.1839 | 0.1643 | 0.1205 | 0.2190 | 0.0509 | 0.2824 | 0.0116 | 0.1729 | 0.0044 | 0.0000 | 0.0196 | 0.0010 | 0.0418 | 0.0068 | 0.0982 | 0.0209 | 0.1483 | 0.0507 | 0.1781 | 0.0989 | 0.1749 | 0.1495 | 0.1477 | 0.2567 | 0.1869 | 0.4155 | 0.1638 | 0.1855 | 0.1048 | 0.0943 | 0.1114 | 0.1006 | 0.1048 | 0.1132 | 0.1201 | 0.1226 | 0.1004 | 0.1164 | 0.1048 | 0.1069 | 0.0873 | 0.0943 | 0.1026 | 0.0660 | 0.0254 | 0.0806 | 0.1569 | 0.1490 | 0.1350 | 0.1060 | 0.1060 | 0.0947 | 0.1464 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 457 | 212 | | 6322 | 18147 | 382.8 | 44.78 | 238.77 | 294.82 | 326 | 348 | 362 | 373 | 384 | 395 | 406 | 419 | 439 | 0.0600 | 1088 | 1.215 | 99.36 | 36.50 | 1 | 0.0386 | 244 | 0.0018 | 29.68 | 6.658 | 0.2214 | 148564.0 | 58400000 | 23200000000 | 9350000000000 | 0.4200 | 0.2268 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0005 | 0.0000 | 0.0033 | 0.0005 | 0.0198 | 0.0108 | 0.0385 | 0.0209 | 0.0480 | 0.0104 | 0.0811 | 0.0223 | 0.8084 | 0.9351 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0015 | 0.0005 | 0.0136 | 0.0108 | 0.0260 | 0.0209 | 0.0246 | 0.0104 | 0.0395 | 0.0223 | 0.8947 | 0.9351 | 0.0536 | 0.0000 | 0.0421 | 0.0000 | 0.0651 | 0.0000 | 0.1303 | 0.0000 | 0.1418 | 0.0000 | 0.2222 | 0.0000 | 0.1188 | 0.0000 | 0.1341 | 0.0000 | 0.0920 | 0.0000 | 0.0012 | 0.0049 | 0.0132 | 0.0292 | 0.0679 | 0.1075 | 0.1161 | 0.1588 | 0.5012 | 17 | 22 | 29 | 46 | 89 | 180 | 301 | 457 | 675 | 0.0295 | 57.83 | 5.943 | 0.4328 | 143927.0 | 117000000 | 112000000000 | 121000000000000 | 0.4463 | 0.1845 | 0.0546 | 0.0038 | 0.1914 | 0.0093 | 0.2906 | 0.1053 | 0.1701 | 0.1693 | 0.1184 | 0.2109 | 0.1042 | 0.1922 | 0.0475 | 0.1153 | 0.0156 | 0.0952 | 0.0078 | 0.0987 | 0.0001 | 0.0005 | 0.0011 | 0.0005 | 0.0034 | 0.0014 | 0.0108 | 0.0082 | 0.0532 | 0.0501 | 0.0872 | 0.0742 | 0.0606 | 0.0519 | 0.0872 | 0.0802 | 0.6963 | 0.7330 | 0.0005 | 0.0004 | 0.0021 | 0.0008 | 0.0042 | 0.0052 | 0.0150 | 0.0185 | 0.0656 | 0.0707 | 0.1028 | 0.1137 | 0.0807 | 0.0882 | 0.1081 | 0.1140 | 0.6208 | 0.5885 | 0.0002 | 0.0016 | 0.0046 | 0.0142 | 0.0602 | 0.0943 | 0.0678 | 0.0986 | 0.6586 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 309 | 735 | | 1819 | 14901 | 73.2 | 15.19 | 136.21 | 157.45 | 56 | 62 | 65 | 67 | 70 | 74 | 79 | 85 | 94 | 0.0571 | 851 | 0.961 | 66.85 | 20.22 | 3 | 0.0995 | 181 | 0.0042 | 13.83 | 5.799 | 0.2858 | 5584.7 | 444991 | 37000000 | 3220000000 | 0.5015 | 0.1554 | 0.0008 | 0.0000 | 0.0047 | 0.0006 | 0.0228 | 0.0012 | 0.0417 | 0.0140 | 0.1133 | 0.0450 | 0.1707 | 0.1040 | 0.1526 | 0.0900 | 0.1794 | 0.1244 | 0.3139 | 0.6209 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0069 | 0.0011 | 0.0202 | 0.0117 | 0.0656 | 0.0362 | 0.1040 | 0.0841 | 0.0807 | 0.0523 | 0.1230 | 0.0885 | 0.5984 | 0.7255 | 0.0095 | 0.0238 | 0.0063 | 0.0357 | 0.0381 | 0.1190 | 0.1175 | 0.2381 | 0.1460 | 0.1905 | 0.2190 | 0.1429 | 0.1238 | 0.0833 | 0.1143 | 0.0833 | 0.2254 | 0.0833 | 0.0025 | 0.0135 | 0.0197 | 0.0492 | 0.1095 | 0.1365 | 0.1267 | 0.1501 | 0.3924 | 14 | 17 | 23 | 40 | 73 | 110 | 160 | 243 | 367 | 0.0319 | 18.03 | 5.311 | 0.4923 | 43340.4 | 19300000 | 10300000000 | 6180000000000 | 0.4512 | 0.1992 | 0.0348 | 0.0006 | 0.1211 | 0.0135 | 0.2124 | 0.0737 | 0.1696 | 0.0995 | 0.1621 | 0.1575 | 0.1286 | 0.1894 | 0.0776 | 0.1317 | 0.0547 | 0.1357 | 0.0391 | 0.1983 | 0.0008 | 0.0000 | 0.0012 | 0.0006 | 0.0050 | 0.0021 | 0.0163 | 0.0107 | 0.0553 | 0.0478 | 0.0947 | 0.0811 | 0.0696 | 0.0552 | 0.0962 | 0.0929 | 0.6610 | 0.7096 | 0.0009 | 0.0008 | 0.0018 | 0.0024 | 0.0075 | 0.0050 | 0.0218 | 0.0214 | 0.0693 | 0.0833 | 0.1160 | 0.1303 | 0.0869 | 0.0844 | 0.1141 | 0.1295 | 0.5816 | 0.5430 | 0.0008 | 0.0010 | 0.0031 | 0.0189 | 0.0617 | 0.1060 | 0.0742 | 0.1094 | 0.6249 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 458 | 196 | | 2487 | 4852 | 502.4 | 108.13 | 28.97 | 67.04 | 323 | 396 | 462 | 498 | 525 | 549 | 572 | 595 | 625 | 0.1008 | 489 | 1.136 | 122.50 | 41.00 | 3 | 0.1186 | 295 | 0.0011 | 45.67 | 6.999 | 0.1815 | 264107.0 | 144000000 | 80400000000 | 45900000000000 | 0.4074 | 0.2236 | 0.0000 | 0.0000 | 0.0007 | 0.0017 | 0.0013 | 0.0017 | 0.0137 | 0.0038 | 0.0586 | 0.0196 | 0.1036 | 0.0325 | 0.0971 | 0.0282 | 0.1153 | 0.0440 | 0.6098 | 0.8684 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0017 | 0.0036 | 0.0038 | 0.0214 | 0.0196 | 0.0300 | 0.0311 | 0.0254 | 0.0230 | 0.0376 | 0.0358 | 0.8821 | 0.8834 | 0.0000 | 0.0000 | 0.0093 | 0.5000 | 0.0231 | 0.5000 | 0.0579 | 0.0000 | 0.1435 | 0.0000 | 0.2176 | 0.0000 | 0.0995 | 0.0000 | 0.1435 | 0.0000 | 0.3056 | 0.0000 | 0.0000 | 0.0021 | 0.0027 | 0.0103 | 0.0397 | 0.0637 | 0.0582 | 0.0794 | 0.7440 | 7 | 9 | 10 | 12 | 13 | 16 | 20 | 25 | 39 | 0.2290 | 1.64 | 2.351 | 0.8187 | 5332.5 | 2350000 | 1240000000 | 703000000000 | 0.6224 | 0.1004 | 0.0481 | 0.0325 | 0.0611 | 0.0293 | 0.0722 | 0.0357 | 0.0907 | 0.0325 | 0.1389 | 0.0523 | 0.1889 | 0.0722 | 0.1611 | 0.1094 | 0.1333 | 0.1665 | 0.1056 | 0.4695 | 0.0208 | 0.0226 | 0.0271 | 0.0203 | 0.0253 | 0.0231 | 0.0316 | 0.0220 | 0.0479 | 0.0365 | 0.0949 | 0.0602 | 0.0723 | 0.0747 | 0.1102 | 0.1169 | 0.5700 | 0.6238 | 0.0212 | 0.0086 | 0.0194 | 0.0107 | 0.0212 | 0.0086 | 0.0300 | 0.0193 | 0.0423 | 0.0428 | 0.0758 | 0.0600 | 0.0406 | 0.0450 | 0.0882 | 0.0878 | 0.6614 | 0.7173 | 0.0202 | 0.0265 | 0.0277 | 0.0429 | 0.0542 | 0.0845 | 0.0605 | 0.0782 | 0.6053 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 409 | 890 | | 816 | 11183 | 89.7 | 9.29 | 105.45 | 153.75 | 78 | 81 | 84 | 87 | 90 | 92 | 95 | 98 | 101 | 0.0640 | 716 | 0.688 | 118.34 | 30.02 | 4 | 0.4142 | 338 | 0.0250 | 2.26 | 3.936 | 0.5414 | 8132.4 | 745123 | 69000000 | 6450000000 | 0.4240 | 0.2141 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0038 | 0.0012 | 0.0166 | 0.0086 | 0.0422 | 0.0319 | 0.0575 | 0.0564 | 0.0665 | 0.0380 | 0.1151 | 0.0576 | 0.6982 | 0.8064 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0012 | 0.0137 | 0.0086 | 0.0373 | 0.0319 | 0.0460 | 0.0564 | 0.0522 | 0.0380 | 0.0646 | 0.0576 | 0.7826 | 0.8064 | 0.1304 | 0.0000 | 0.0870 | 0.0000 | 0.0870 | 0.0000 | 0.2174 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.0870 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0048 | 0.0096 | 0.0265 | 0.0265 | 0.0964 | 0.1084 | 0.1084 | 0.1880 | 0.4313 | 12 | 15 | 19 | 25 | 36 | 56 | 93 | 175 | 308 | 0.0583 | 19.57 | 4.627 | 0.5749 | 34757.8 | 18600000 | 13100000000 | 11000000000000 | 0.5602 | 0.1268 | 0.0620 | 0.0049 | 0.1860 | 0.0220 | 0.2709 | 0.1170 | 0.1685 | 0.1506 | 0.1119 | 0.1935 | 0.0876 | 0.1911 | 0.0539 | 0.1066 | 0.0270 | 0.0980 | 0.0323 | 0.1164 | 0.0006 | 0.0010 | 0.0025 | 0.0017 | 0.0048 | 0.0048 | 0.0202 | 0.0167 | 0.0663 | 0.0628 | 0.1003 | 0.0944 | 0.0621 | 0.0604 | 0.1056 | 0.0980 | 0.6376 | 0.6603 | 0.0011 | 0.0004 | 0.0011 | 0.0008 | 0.0032 | 0.0054 | 0.0231 | 0.0233 | 0.0774 | 0.0848 | 0.1214 | 0.1431 | 0.0781 | 0.0809 | 0.1256 | 0.1268 | 0.5692 | 0.5344 | 0.0010 | 0.0016 | 0.0058 | 0.0214 | 0.0672 | 0.1140 | 0.0643 | 0.1191 | 0.6056 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 820 | 689 | | 340 | 1923 | 397.1 | 79.43 | 199.34 | 201.26 | 294 | 333 | 352 | 372 | 390 | 408 | 435 | 465 | 504 | 0.1394 | 268 | 1.182 | 145.07 | 47.10 | 3 | 1.0029 | 341 | 0.0036 | 115.51 | 5.687 | 0.1125 | 163958.0 | 70300000 | 31200000000 | 14300000000000 | 0.3965 | 0.2306 | 0.0000 | 0.0000 | 0.0174 | 0.0000 | 0.0217 | 0.0000 | 0.0957 | 0.0245 | 0.1478 | 0.0890 | 0.1913 | 0.1196 | 0.1783 | 0.0706 | 0.1043 | 0.1135 | 0.2435 | 0.5828 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0241 | 0.0118 | 0.1069 | 0.0737 | 0.1621 | 0.1121 | 0.1241 | 0.0619 | 0.1241 | 0.1003 | 0.4517 | 0.6401 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0500 | 0.2308 | 0.1333 | 0.0000 | 0.2000 | 0.3077 | 0.2167 | 0.1538 | 0.0833 | 0.1538 | 0.1500 | 0.1538 | 0.1667 | 0.0000 | 0.0000 | 0.0000 | 0.0189 | 0.0818 | 0.1635 | 0.2075 | 0.1258 | 0.1635 | 0.2390 | 20 | 36 | 64 | 93 | 120 | 173 | 254 | 366 | 476 | 0.0098 | 59.99 | 5.843 | 0.3632 | 80219.5 | 45700000 | 32800000000 | 28000000000000 | 0.5269 | 0.1237 | 0.0813 | 0.0000 | 0.2536 | 0.0321 | 0.3971 | 0.1514 | 0.1579 | 0.2041 | 0.0478 | 0.2110 | 0.0287 | 0.2064 | 0.0144 | 0.0940 | 0.0191 | 0.0550 | 0.0000 | 0.0459 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0012 | 0.0042 | 0.0135 | 0.0156 | 0.0800 | 0.0582 | 0.1441 | 0.1163 | 0.0985 | 0.0789 | 0.1195 | 0.1184 | 0.5431 | 0.6075 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0057 | 0.0332 | 0.0361 | 0.1144 | 0.1347 | 0.1841 | 0.1822 | 0.1061 | 0.1101 | 0.1426 | 0.1480 | 0.4179 | 0.3833 | 0.0000 | 0.0000 | 0.0000 | 0.0142 | 0.1095 | 0.1551 | 0.1053 | 0.1351 | 0.4808 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 193 | 840 | | 364 | 9991 | 79.4 | 12.33 | 120.69 | 125.11 | 64 | 69 | 71 | 74 | 78 | 82 | 86 | 91 | 97 | 0.0656 | 655 | 0.892 | 100.23 | 30.02 | 0 | 0.7033 | 256 | 0.0097 | 8.20 | 4.818 | 0.3329 | 6458.0 | 537560 | 45800000 | 3980000000 | 0.4026 | 0.2222 | 0.0000 | 0.0000 | 0.0248 | 0.0028 | 0.0106 | 0.0055 | 0.0496 | 0.0138 | 0.1028 | 0.0608 | 0.1950 | 0.1326 | 0.1915 | 0.0856 | 0.2340 | 0.1105 | 0.1915 | 0.5884 | 0.0000 | 0.0000 | 0.0210 | 0.0027 | 0.0060 | 0.0055 | 0.0330 | 0.0137 | 0.0571 | 0.0604 | 0.1171 | 0.1319 | 0.0781 | 0.0742 | 0.1171 | 0.0934 | 0.5706 | 0.6181 | 0.0196 | 0.0000 | 0.0980 | 1.0000 | 0.0392 | 0.0000 | 0.2549 | 0.0000 | 0.1765 | 0.0000 | 0.2157 | 0.0000 | 0.0980 | 0.0000 | 0.0980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0229 | 0.0571 | 0.0400 | 0.0971 | 0.1371 | 0.1371 | 0.1771 | 0.3314 | 24 | 37 | 47 | 57 | 70 | 90 | 126 | 190 | 293 | 0.0082 | 25.67 | 5.863 | 0.4219 | 30214.6 | 11500000 | 5470000000 | 2990000000000 | 0.6670 | 0.0790 | 0.0168 | 0.0063 | 0.0841 | 0.0145 | 0.1639 | 0.0396 | 0.1869 | 0.0903 | 0.1913 | 0.1538 | 0.1665 | 0.1778 | 0.0939 | 0.1436 | 0.0709 | 0.1429 | 0.0257 | 0.2312 | 0.0013 | 0.0029 | 0.0042 | 0.0050 | 0.0088 | 0.0091 | 0.0255 | 0.0213 | 0.0682 | 0.0615 | 0.1043 | 0.0886 | 0.0823 | 0.0797 | 0.1139 | 0.1042 | 0.5915 | 0.6276 | 0.0008 | 0.0009 | 0.0049 | 0.0070 | 0.0167 | 0.0127 | 0.0318 | 0.0417 | 0.0864 | 0.0961 | 0.1262 | 0.1298 | 0.0936 | 0.1039 | 0.1259 | 0.1373 | 0.5136 | 0.4706 | 0.0016 | 0.0055 | 0.0109 | 0.0257 | 0.0792 | 0.1136 | 0.0911 | 0.1171 | 0.5553 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1028 | 672 | | 465 | 2154 | 115.4 | 21.95 | 94.06 | 88.63 | 88 | 97 | 102 | 107 | 113 | 119 | 127 | 135 | 145 | 0.1467 | 316 | 0.423 | 90.70 | 21.40 | 1 | 0.5978 | 278 | 0.0052 | 16.34 | 5.463 | 0.2803 | 13796.9 | 1710000 | 218000000 | 28800000000 | 0.4162 | 0.2196 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0247 | 0.0022 | 0.0556 | 0.0111 | 0.1049 | 0.0509 | 0.1852 | 0.0907 | 0.1420 | 0.0575 | 0.1821 | 0.1062 | 0.3025 | 0.6814 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0022 | 0.0273 | 0.0086 | 0.0695 | 0.0452 | 0.1042 | 0.0839 | 0.0720 | 0.0344 | 0.1117 | 0.0796 | 0.6104 | 0.7462 | 0.0000 | 0.0000 | 0.0380 | 0.1538 | 0.0380 | 0.0000 | 0.1139 | 0.1538 | 0.1519 | 0.3846 | 0.2152 | 0.0000 | 0.1392 | 0.1538 | 0.1139 | 0.1538 | 0.1899 | 0.0000 | 0.0000 | 0.0045 | 0.0179 | 0.0538 | 0.1345 | 0.1211 | 0.1211 | 0.1704 | 0.3767 | 17 | 26 | 35 | 44 | 58 | 78 | 107 | 164 | 229 | 0.0192 | 12.21 | 4.935 | 0.4816 | 16699.0 | 4090000 | 1190000000 | 384000000000 | 0.5433 | 0.1288 | 0.0185 | 0.0036 | 0.1218 | 0.0145 | 0.1808 | 0.0416 | 0.1734 | 0.1139 | 0.2251 | 0.1953 | 0.0959 | 0.1664 | 0.0812 | 0.1356 | 0.0554 | 0.1447 | 0.0480 | 0.1844 | 0.0000 | 0.0000 | 0.0056 | 0.0009 | 0.0090 | 0.0027 | 0.0124 | 0.0192 | 0.0710 | 0.0602 | 0.1150 | 0.0794 | 0.0744 | 0.0776 | 0.1488 | 0.1487 | 0.5637 | 0.6113 | 0.0016 | 0.0000 | 0.0032 | 0.0018 | 0.0065 | 0.0147 | 0.0260 | 0.0313 | 0.0666 | 0.0792 | 0.1380 | 0.1455 | 0.0893 | 0.0958 | 0.1347 | 0.1602 | 0.5341 | 0.4715 | 0.0014 | 0.0082 | 0.0109 | 0.0301 | 0.0657 | 0.1012 | 0.0821 | 0.1477 | 0.5527 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 568 | 142 | | 3390 | 3676 | 488.2 | 76.89 | 55.99 | 95.47 | 384 | 420 | 448 | 473 | 493 | 513 | 533 | 556 | 587 | 0.1317 | 484 | 0.859 | 109.18 | 23.32 | 5 | 0.0752 | 255 | 0.0012 | 41.51 | 6.959 | 0.2091 | 244289.0 | 125000000 | 65200000000 | 34600000000000 | 0.4456 | 0.2022 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0133 | 0.0009 | 0.0451 | 0.0139 | 0.0863 | 0.0237 | 0.0833 | 0.0160 | 0.1064 | 0.0261 | 0.6638 | 0.9194 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0050 | 0.0009 | 0.0220 | 0.0139 | 0.0441 | 0.0237 | 0.0414 | 0.0154 | 0.0588 | 0.0231 | 0.8284 | 0.9230 | 0.0028 | 0.0000 | 0.0113 | 1.0000 | 0.0395 | 0.0000 | 0.1073 | 0.0000 | 0.1638 | 0.0000 | 0.2147 | 0.0000 | 0.1243 | 0.0000 | 0.1356 | 0.0000 | 0.2006 | 0.0000 | 0.0006 | 0.0017 | 0.0045 | 0.0195 | 0.0658 | 0.1155 | 0.1016 | 0.1267 | 0.5642 | 9 | 11 | 12 | 14 | 17 | 20 | 25 | 75 | 169 | 0.1554 | 6.68 | 3.147 | 0.7267 | 12247.2 | 4240000 | 1770000000 | 834000000000 | 0.4752 | 0.1492 | 0.0192 | 0.0284 | 0.0769 | 0.0355 | 0.1731 | 0.1277 | 0.3462 | 0.1489 | 0.1346 | 0.1915 | 0.1346 | 0.1773 | 0.1154 | 0.1206 | 0.0000 | 0.0709 | 0.0000 | 0.0993 | 0.0000 | 0.0046 | 0.0025 | 0.0058 | 0.0012 | 0.0116 | 0.0037 | 0.0127 | 0.0160 | 0.0197 | 0.0197 | 0.0313 | 0.0271 | 0.0174 | 0.0406 | 0.0440 | 0.8892 | 0.8530 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0028 | 0.0039 | 0.0083 | 0.0211 | 0.0221 | 0.0316 | 0.0456 | 0.0395 | 0.0415 | 0.0684 | 0.0692 | 0.8329 | 0.8105 | 0.0000 | 0.0000 | 0.0013 | 0.0038 | 0.0189 | 0.0215 | 0.0278 | 0.0556 | 0.8712 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 401 | 465 | | 5688 | 21468 | 395.0 | 83.99 | 124.18 | 239.02 | 290 | 326 | 352 | 373 | 392 | 410 | 430 | 457 | 504 | 0.0522 | 1120 | 1.175 | 146.10 | 54.92 | 1 | 0.0647 | 368 | 0.0007 | 85.77 | 7.563 | 0.1400 | 163082.0 | 70200000 | 31500000000 | 14700000000000 | 0.4503 | 0.2076 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0036 | 0.0000 | 0.0145 | 0.0009 | 0.0614 | 0.0220 | 0.1338 | 0.0403 | 0.1196 | 0.0438 | 0.1527 | 0.0645 | 0.5131 | 0.8284 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0036 | 0.0004 | 0.0302 | 0.0151 | 0.0598 | 0.0258 | 0.0550 | 0.0211 | 0.0858 | 0.0337 | 0.7648 | 0.9040 | 0.0011 | 0.0168 | 0.0078 | 0.0294 | 0.0343 | 0.0546 | 0.0676 | 0.1723 | 0.1495 | 0.1765 | 0.2137 | 0.2185 | 0.0952 | 0.0840 | 0.1384 | 0.0840 | 0.2924 | 0.1639 | 0.0018 | 0.0025 | 0.0094 | 0.0305 | 0.0864 | 0.1409 | 0.1097 | 0.1543 | 0.4644 | 7 | 8 | 9 | 11 | 13 | 19 | 59 | 166 | 460 | 0.2326 | 28.31 | 3.763 | 0.6555 | 72548.9 | 59000000 | 55500000000 | 57500000000000 | 0.4057 | 0.2332 | 0.0627 | 0.0034 | 0.2304 | 0.0282 | 0.2413 | 0.1477 | 0.1242 | 0.1167 | 0.1363 | 0.1635 | 0.0893 | 0.1860 | 0.0555 | 0.1037 | 0.0483 | 0.1020 | 0.0121 | 0.1488 | 0.0000 | 0.0002 | 0.0002 | 0.0000 | 0.0007 | 0.0015 | 0.0069 | 0.0057 | 0.0502 | 0.0393 | 0.0700 | 0.0667 | 0.0470 | 0.0434 | 0.0722 | 0.0667 | 0.7528 | 0.7766 | 0.0000 | 0.0002 | 0.0007 | 0.0007 | 0.0015 | 0.0021 | 0.0071 | 0.0088 | 0.0563 | 0.0601 | 0.0801 | 0.0852 | 0.0541 | 0.0560 | 0.0781 | 0.0805 | 0.7221 | 0.7063 | 0.0000 | 0.0000 | 0.0024 | 0.0088 | 0.0529 | 0.0768 | 0.0489 | 0.0729 | 0.7373 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1068 | 588 | | 752 | 8804 | 837.7 | 183.87 | 21.91 | 27.10 | 548 | 654 | 750 | 824 | 893 | 932 | 956 | 997 | 1042 | 0.0601 | 529 | 0.815 | 73.00 | 17.00 | 2 | 0.2420 | 182 | 0.0018 | 141.74 | 6.411 | 0.1068 | 735551.0 | 669000000 | 625000000000 | 596000000000000 | 0.3650 | 0.2575 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0029 | 0.0667 | 0.0345 | 0.1644 | 0.0576 | 0.1111 | 0.0273 | 0.1333 | 0.0604 | 0.5156 | 0.8173 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0051 | 0.0029 | 0.0341 | 0.0345 | 0.0631 | 0.0575 | 0.0341 | 0.0273 | 0.0546 | 0.0489 | 0.8089 | 0.8290 | 0.0000 | 1.0000 | 0.0000 | 0.0000 | 0.0147 | 0.0000 | 0.0662 | 0.0000 | 0.1103 | 0.0000 | 0.2132 | 0.0000 | 0.0882 | 0.0000 | 0.1324 | 0.0000 | 0.3750 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0068 | 0.0430 | 0.0724 | 0.0385 | 0.0747 | 0.7647 | 6 | 7 | 9 | 10 | 12 | 15 | 20 | 29 | 49 | 0.1218 | 2.34 | 3.113 | 0.7219 | 1214.4 | 130232 | 20200000 | 4000000000 | 0.4480 | 0.1854 | 0.0474 | 0.0344 | 0.0720 | 0.0374 | 0.1147 | 0.0502 | 0.1735 | 0.0709 | 0.1782 | 0.1115 | 0.1640 | 0.1388 | 0.1393 | 0.1286 | 0.0891 | 0.1916 | 0.0218 | 0.2366 | 0.0077 | 0.0179 | 0.0123 | 0.0163 | 0.0143 | 0.0191 | 0.0299 | 0.0253 | 0.0486 | 0.0447 | 0.0615 | 0.0613 | 0.0745 | 0.0513 | 0.0968 | 0.0970 | 0.6544 | 0.6671 | 0.0067 | 0.0030 | 0.0062 | 0.0085 | 0.0154 | 0.0164 | 0.0308 | 0.0413 | 0.0677 | 0.0735 | 0.0800 | 0.0874 | 0.0830 | 0.0923 | 0.1148 | 0.1148 | 0.5956 | 0.5628 | 0.0045 | 0.0081 | 0.0134 | 0.0292 | 0.0564 | 0.0714 | 0.0673 | 0.1039 | 0.6458 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1055 | 344 | | 487 | 5051 | 49.0 | 12.36 | 116.43 | 167.87 | 32 | 38 | 43 | 46 | 49 | 52 | 55 | 59 | 65 | 0.0810 | 409 | 1.242 | 45.35 | 19.21 | 2 | 0.2485 | 121 | 0.0057 | 11.72 | 5.356 | 0.3095 | 2555.8 | 140162 | 8020000 | 475000000 | 0.4385 | 0.1798 | 0.0000 | 0.0000 | 0.0075 | 0.0000 | 0.0522 | 0.0000 | 0.1045 | 0.0189 | 0.1604 | 0.0731 | 0.1604 | 0.0967 | 0.1642 | 0.1250 | 0.1604 | 0.1627 | 0.1903 | 0.5236 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0000 | 0.0293 | 0.0177 | 0.0745 | 0.0576 | 0.0931 | 0.0665 | 0.1356 | 0.0687 | 0.1330 | 0.1020 | 0.5319 | 0.6874 | 0.0093 | 0.0370 | 0.0278 | 0.1111 | 0.0185 | 0.1481 | 0.1574 | 0.1852 | 0.1296 | 0.2222 | 0.2130 | 0.1481 | 0.1481 | 0.1111 | 0.1389 | 0.0000 | 0.1574 | 0.0370 | 0.0000 | 0.0000 | 0.0038 | 0.0651 | 0.1149 | 0.1609 | 0.1686 | 0.1801 | 0.3065 | 21 | 24 | 27 | 33 | 48 | 74 | 108 | 161 | 274 | 0.0561 | 13.35 | 4.308 | 0.5688 | 41728.7 | 26200000 | 21000000000 | 19200000000000 | 0.6628 | 0.0772 | 0.0483 | 0.0009 | 0.1324 | 0.0250 | 0.1843 | 0.1026 | 0.1395 | 0.1100 | 0.1467 | 0.1590 | 0.1521 | 0.1654 | 0.0912 | 0.1451 | 0.0644 | 0.1146 | 0.0411 | 0.1774 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0035 | 0.0029 | 0.0260 | 0.0211 | 0.0860 | 0.0694 | 0.1166 | 0.0991 | 0.0912 | 0.0804 | 0.1396 | 0.1197 | 0.5361 | 0.6060 | 0.0009 | 0.0000 | 0.0043 | 0.0050 | 0.0068 | 0.0099 | 0.0324 | 0.0417 | 0.1107 | 0.1202 | 0.1388 | 0.1400 | 0.0894 | 0.1043 | 0.1516 | 0.1589 | 0.4651 | 0.4201 | 0.0014 | 0.0007 | 0.0085 | 0.0318 | 0.1108 | 0.1200 | 0.0924 | 0.1623 | 0.4721 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 937 | 869 | | 4358 | 4787 | 150.5 | 35.67 | 215.35 | 167.50 | 110 | 121 | 130 | 138 | 145 | 153 | 163 | 177 | 197 | 0.1249 | 598 | 1.001 | 107.62 | 26.02 | 1 | 0.0569 | 248 | 0.0019 | 28.98 | 6.582 | 0.2338 | 23927.0 | 4030000 | 718000000 | 136000000000 | 0.4618 | 0.1848 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0307 | 0.0025 | 0.0928 | 0.0234 | 0.1506 | 0.0557 | 0.1593 | 0.0605 | 0.1827 | 0.0891 | 0.3778 | 0.7688 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0113 | 0.0009 | 0.0423 | 0.0174 | 0.0675 | 0.0300 | 0.0805 | 0.0244 | 0.1032 | 0.0449 | 0.6920 | 0.8824 | 0.0053 | 0.0070 | 0.0119 | 0.0105 | 0.0185 | 0.0281 | 0.0793 | 0.1333 | 0.1506 | 0.2702 | 0.2127 | 0.1754 | 0.1136 | 0.1053 | 0.1532 | 0.1368 | 0.2550 | 0.1333 | 0.0032 | 0.0048 | 0.0117 | 0.0472 | 0.0881 | 0.1342 | 0.1146 | 0.1363 | 0.4599 | 40 | 68 | 99 | 133 | 170 | 220 | 274 | 347 | 446 | 0.0016 | 96.66 | 7.105 | 0.2131 | 74423.1 | 33600000 | 18100000000 | 10900000000000 | 0.5058 | 0.1647 | 0.0429 | 0.0024 | 0.1767 | 0.0102 | 0.2798 | 0.0783 | 0.1951 | 0.1428 | 0.1325 | 0.2055 | 0.0994 | 0.2127 | 0.0393 | 0.1350 | 0.0172 | 0.1183 | 0.0172 | 0.0950 | 0.0008 | 0.0007 | 0.0013 | 0.0020 | 0.0029 | 0.0038 | 0.0256 | 0.0133 | 0.0797 | 0.0673 | 0.1472 | 0.1206 | 0.1065 | 0.0823 | 0.1254 | 0.1209 | 0.5107 | 0.5891 | 0.0000 | 0.0016 | 0.0051 | 0.0048 | 0.0134 | 0.0104 | 0.0535 | 0.0670 | 0.1217 | 0.1316 | 0.1637 | 0.2041 | 0.1312 | 0.1276 | 0.1548 | 0.1515 | 0.3567 | 0.3014 | 0.0010 | 0.0035 | 0.0051 | 0.0238 | 0.1190 | 0.1570 | 0.1023 | 0.1489 | 0.4392 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1107 | 725 | | 3073 | 3969 | 338.0 | 79.28 | 111.41 | 132.27 | 234 | 267 | 290 | 314 | 335 | 356 | 378 | 405 | 441 | 0.1217 | 483 | 1.226 | 141.20 | 63.63 | 1 | 0.1276 | 392 | 0.0012 | 36.06 | 6.918 | 0.1908 | 120541.0 | 45200000 | 17700000000 | 7230000000000 | 0.4322 | 0.2106 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0044 | 0.0000 | 0.0183 | 0.0046 | 0.0759 | 0.0201 | 0.1506 | 0.0466 | 0.1440 | 0.0508 | 0.1849 | 0.0756 | 0.4219 | 0.8019 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0017 | 0.0000 | 0.0079 | 0.0033 | 0.0277 | 0.0147 | 0.0513 | 0.0287 | 0.0484 | 0.0184 | 0.0778 | 0.0277 | 0.7854 | 0.9068 | 0.0033 | 0.0248 | 0.0082 | 0.0124 | 0.0131 | 0.0559 | 0.0784 | 0.1801 | 0.1373 | 0.2236 | 0.2124 | 0.1677 | 0.1193 | 0.1242 | 0.1373 | 0.1118 | 0.2909 | 0.0994 | 0.0007 | 0.0013 | 0.0060 | 0.0219 | 0.0672 | 0.1203 | 0.1110 | 0.1356 | 0.5359 | 12 | 23 | 35 | 48 | 64 | 85 | 116 | 178 | 274 | 0.0254 | 11.05 | 4.985 | 0.5393 | 29902.0 | 13200000 | 7610000000 | 5130000000000 | 0.5025 | 0.1307 | 0.0142 | 0.0010 | 0.0548 | 0.0120 | 0.1258 | 0.0239 | 0.1400 | 0.0658 | 0.1826 | 0.1396 | 0.1562 | 0.1854 | 0.1014 | 0.1206 | 0.1055 | 0.1356 | 0.1197 | 0.3161 | 0.0006 | 0.0000 | 0.0000 | 0.0026 | 0.0019 | 0.0036 | 0.0130 | 0.0104 | 0.0467 | 0.0410 | 0.0746 | 0.0607 | 0.0655 | 0.0524 | 0.0966 | 0.0841 | 0.7010 | 0.7451 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0038 | 0.0043 | 0.0076 | 0.0152 | 0.0725 | 0.0769 | 0.0925 | 0.1073 | 0.0620 | 0.0921 | 0.1115 | 0.1138 | 0.6501 | 0.5894 | 0.0024 | 0.0016 | 0.0041 | 0.0114 | 0.0571 | 0.0702 | 0.0637 | 0.0980 | 0.6914 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 963 | 51 | | 463 | 2383 | 135.5 | 54.95 | 285.62 | 357.76 | 57 | 79 | 96 | 118 | 140 | 159 | 176 | 191 | 206 | 0.1389 | 331 | 0.806 | 83.49 | 17.80 | 1 | 0.4125 | 191 | 0.0030 | 40.37 | 5.894 | 0.2035 | 21382.7 | 3690000 | 675000000 | 128000000000 | 0.3277 | 0.2693 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0794 | 0.0000 | 0.2063 | 0.0037 | 0.3016 | 0.0967 | 0.2381 | 0.2528 | 0.0952 | 0.1413 | 0.0635 | 0.1450 | 0.0159 | 0.3606 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0066 | 0.0027 | 0.0459 | 0.0495 | 0.1180 | 0.1016 | 0.0525 | 0.0330 | 0.0721 | 0.0549 | 0.7049 | 0.7582 | 0.0000 | 0.0000 | 0.0000 | 0.0105 | 0.0000 | 0.0000 | 0.0168 | 0.0947 | 0.0726 | 0.1053 | 0.2123 | 0.2947 | 0.0894 | 0.0526 | 0.1285 | 0.1053 | 0.4804 | 0.3368 | 0.0000 | 0.0000 | 0.0000 | 0.0124 | 0.0664 | 0.1286 | 0.0747 | 0.1079 | 0.6100 | 17 | 24 | 32 | 51 | 103 | 203 | 340 | 571 | 860 | 0.0209 | 106.06 | 5.674 | 0.3655 | 209519.0 | 201000000 | 220000000000 | 261000000000000 | 0.5461 | 0.1235 | 0.1000 | 0.0053 | 0.1944 | 0.0317 | 0.2833 | 0.1504 | 0.1389 | 0.1926 | 0.1444 | 0.1636 | 0.0833 | 0.1900 | 0.0444 | 0.0765 | 0.0056 | 0.1187 | 0.0056 | 0.0712 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0169 | 0.0137 | 0.0349 | 0.0235 | 0.0992 | 0.0832 | 0.1680 | 0.1566 | 0.0891 | 0.0861 | 0.1184 | 0.1252 | 0.4724 | 0.5117 | 0.0057 | 0.0016 | 0.0127 | 0.0109 | 0.0255 | 0.0264 | 0.0368 | 0.0358 | 0.0990 | 0.0995 | 0.1457 | 0.1384 | 0.0905 | 0.1151 | 0.1132 | 0.1073 | 0.4710 | 0.4650 | 0.0012 | 0.0037 | 0.0224 | 0.0387 | 0.1110 | 0.1459 | 0.1010 | 0.1035 | 0.4726 |