High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 568 | 142 | | 3390 | 3676 | 488.2 | 76.89 | 55.99 | 95.47 | 384 | 420 | 448 | 473 | 493 | 513 | 533 | 556 | 587 | 0.1317 | 484 | 0.859 | 109.18 | 23.32 | 5 | 0.0752 | 255 | 0.0012 | 41.51 | 6.959 | 0.2091 | 244289.0 | 125000000 | 65200000000 | 34600000000000 | 0.4456 | 0.2022 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0133 | 0.0009 | 0.0451 | 0.0139 | 0.0863 | 0.0237 | 0.0833 | 0.0160 | 0.1064 | 0.0261 | 0.6638 | 0.9194 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0050 | 0.0009 | 0.0220 | 0.0139 | 0.0441 | 0.0237 | 0.0414 | 0.0154 | 0.0588 | 0.0231 | 0.8284 | 0.9230 | 0.0028 | 0.0000 | 0.0113 | 1.0000 | 0.0395 | 0.0000 | 0.1073 | 0.0000 | 0.1638 | 0.0000 | 0.2147 | 0.0000 | 0.1243 | 0.0000 | 0.1356 | 0.0000 | 0.2006 | 0.0000 | 0.0006 | 0.0017 | 0.0045 | 0.0195 | 0.0658 | 0.1155 | 0.1016 | 0.1267 | 0.5642 | 9 | 11 | 12 | 14 | 17 | 20 | 25 | 75 | 169 | 0.1554 | 6.68 | 3.147 | 0.7267 | 12247.2 | 4240000 | 1770000000 | 834000000000 | 0.4752 | 0.1492 | 0.0192 | 0.0284 | 0.0769 | 0.0355 | 0.1731 | 0.1277 | 0.3462 | 0.1489 | 0.1346 | 0.1915 | 0.1346 | 0.1773 | 0.1154 | 0.1206 | 0.0000 | 0.0709 | 0.0000 | 0.0993 | 0.0000 | 0.0046 | 0.0025 | 0.0058 | 0.0012 | 0.0116 | 0.0037 | 0.0127 | 0.0160 | 0.0197 | 0.0197 | 0.0313 | 0.0271 | 0.0174 | 0.0406 | 0.0440 | 0.8892 | 0.8530 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0028 | 0.0039 | 0.0083 | 0.0211 | 0.0221 | 0.0316 | 0.0456 | 0.0395 | 0.0415 | 0.0684 | 0.0692 | 0.8329 | 0.8105 | 0.0000 | 0.0000 | 0.0013 | 0.0038 | 0.0189 | 0.0215 | 0.0278 | 0.0556 | 0.8712 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1108 | 239 | | 5108 | 12529 | 286.7 | 70.87 | 214.74 | 352.40 | 171 | 236 | 266 | 284 | 299 | 315 | 328 | 344 | 365 | 0.0797 | 998 | 0.558 | 111.13 | 15.52 | 4 | 0.0484 | 247 | 0.0020 | 16.33 | 6.555 | 0.2615 | 87243.0 | 27600000 | 9000000000 | 3000000000000 | 0.3894 | 0.2353 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0025 | 0.0004 | 0.0143 | 0.0011 | 0.0584 | 0.0180 | 0.0901 | 0.0332 | 0.0841 | 0.0276 | 0.1336 | 0.0427 | 0.6155 | 0.8769 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0007 | 0.0180 | 0.0141 | 0.0245 | 0.0255 | 0.0159 | 0.0137 | 0.0327 | 0.0196 | 0.9084 | 0.9264 | 0.0060 | 0.0200 | 0.0109 | 0.1000 | 0.0268 | 0.1400 | 0.0625 | 0.1500 | 0.1240 | 0.1900 | 0.1488 | 0.1800 | 0.1399 | 0.1200 | 0.1290 | 0.0700 | 0.3522 | 0.0300 | 0.0013 | 0.0007 | 0.0040 | 0.0131 | 0.0368 | 0.0646 | 0.0703 | 0.1078 | 0.7014 | 8 | 10 | 13 | 17 | 22 | 32 | 138 | 460 | 810 | 0.1100 | 11.85 | 3.914 | 0.5579 | 170291.0 | 167000000 | 181000000000 | 211000000000000 | 0.5996 | 0.0926 | 0.0347 | 0.0084 | 0.1262 | 0.0139 | 0.2429 | 0.0446 | 0.1767 | 0.0990 | 0.2019 | 0.1660 | 0.1703 | 0.2106 | 0.0315 | 0.1381 | 0.0126 | 0.1367 | 0.0032 | 0.1827 | 0.0006 | 0.0000 | 0.0006 | 0.0000 | 0.0014 | 0.0003 | 0.0037 | 0.0024 | 0.0292 | 0.0286 | 0.0404 | 0.0329 | 0.0388 | 0.0347 | 0.0584 | 0.0583 | 0.8270 | 0.8428 | 0.0000 | 0.0006 | 0.0000 | 0.0010 | 0.0012 | 0.0003 | 0.0040 | 0.0055 | 0.0339 | 0.0372 | 0.0456 | 0.0486 | 0.0395 | 0.0466 | 0.0688 | 0.0696 | 0.8070 | 0.7905 | 0.0000 | 0.0000 | 0.0006 | 0.0038 | 0.0337 | 0.0391 | 0.0399 | 0.0609 | 0.8219 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1052 | 727 | | 435 | 10158 | 216.6 | 37.95 | 134.54 | 228.49 | 169 | 184 | 193 | 205 | 215 | 223 | 235 | 249 | 268 | 0.0475 | 483 | 1.039 | 156.49 | 50.48 | 1 | 0.9218 | 401 | 0.0052 | 14.90 | 5.415 | 0.3014 | 48369.5 | 11100000 | 2630000000 | 636000000000 | 0.4349 | 0.2080 | 0.0000 | 0.0000 | 0.0096 | 0.0000 | 0.0096 | 0.0000 | 0.0382 | 0.0047 | 0.1019 | 0.0606 | 0.1656 | 0.0629 | 0.1624 | 0.0606 | 0.1943 | 0.0956 | 0.3185 | 0.7156 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0186 | 0.0023 | 0.0849 | 0.0621 | 0.1088 | 0.0552 | 0.0928 | 0.0437 | 0.1432 | 0.0759 | 0.5517 | 0.7609 | 0.0000 | 0.1667 | 0.0000 | 0.0000 | 0.0635 | 0.1667 | 0.1905 | 0.3333 | 0.1429 | 0.3333 | 0.2540 | 0.0000 | 0.1270 | 0.0000 | 0.0635 | 0.0000 | 0.1587 | 0.0000 | 0.0000 | 0.0095 | 0.0237 | 0.0616 | 0.1754 | 0.1469 | 0.1280 | 0.1801 | 0.2749 | 5 | 7 | 8 | 9 | 11 | 16 | 98 | 264 | 495 | 0.1308 | 20.25 | 3.815 | 0.5357 | 70302.5 | 49000000 | 40900000000 | 40000000000000 | 0.5326 | 0.1283 | 0.0600 | 0.0028 | 0.2086 | 0.0308 | 0.2229 | 0.1413 | 0.2086 | 0.1636 | 0.1400 | 0.2070 | 0.0686 | 0.1930 | 0.0514 | 0.1035 | 0.0371 | 0.0867 | 0.0029 | 0.0713 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0037 | 0.0047 | 0.0269 | 0.0233 | 0.0561 | 0.0472 | 0.0326 | 0.0315 | 0.0668 | 0.0585 | 0.8136 | 0.8348 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0011 | 0.0020 | 0.0049 | 0.0053 | 0.0377 | 0.0422 | 0.0681 | 0.0763 | 0.0518 | 0.0666 | 0.0883 | 0.0849 | 0.7477 | 0.7223 | 0.0000 | 0.0000 | 0.0011 | 0.0029 | 0.0350 | 0.0622 | 0.0404 | 0.0733 | 0.7851 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 710 | 226 | | 10638 | 31624 | 385.7 | 96.25 | 128.74 | 201.92 | 261 | 301 | 330 | 358 | 383 | 410 | 437 | 468 | 511 | 0.0395 | 1248 | 1.125 | 80.96 | 32.70 | 1 | 0.0205 | 218 | 0.0007 | 46.96 | 7.474 | 0.1736 | 158052.0 | 68300000 | 30900000000 | 14600000000000 | 0.4592 | 0.1972 | 0.0007 | 0.0000 | 0.0012 | 0.0000 | 0.0092 | 0.0002 | 0.0215 | 0.0023 | 0.0807 | 0.0217 | 0.1548 | 0.0477 | 0.1521 | 0.0530 | 0.1775 | 0.0756 | 0.4023 | 0.7994 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0000 | 0.0071 | 0.0011 | 0.0308 | 0.0141 | 0.0563 | 0.0286 | 0.0517 | 0.0248 | 0.0718 | 0.0362 | 0.7784 | 0.8951 | 0.0031 | 0.0050 | 0.0093 | 0.0268 | 0.0194 | 0.0385 | 0.0552 | 0.1122 | 0.1254 | 0.2111 | 0.1762 | 0.1960 | 0.1219 | 0.1122 | 0.1524 | 0.1374 | 0.3370 | 0.1608 | 0.0006 | 0.0025 | 0.0046 | 0.0208 | 0.0594 | 0.1029 | 0.0892 | 0.1124 | 0.6077 | 6 | 7 | 8 | 10 | 13 | 26 | 121 | 273 | 445 | 0.1884 | 22.33 | 4.262 | 0.6114 | 57343.9 | 33100000 | 22000000000 | 16300000000000 | 0.4979 | 0.1312 | 0.0634 | 0.0031 | 0.2215 | 0.0274 | 0.3281 | 0.1449 | 0.1801 | 0.1860 | 0.1167 | 0.2111 | 0.0542 | 0.1939 | 0.0193 | 0.0950 | 0.0119 | 0.0923 | 0.0046 | 0.0464 | 0.0001 | 0.0002 | 0.0001 | 0.0007 | 0.0014 | 0.0009 | 0.0035 | 0.0033 | 0.0325 | 0.0296 | 0.0490 | 0.0435 | 0.0394 | 0.0311 | 0.0566 | 0.0537 | 0.8173 | 0.8370 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0006 | 0.0049 | 0.0057 | 0.0367 | 0.0435 | 0.0707 | 0.0771 | 0.0468 | 0.0543 | 0.0747 | 0.0844 | 0.7660 | 0.7341 | 0.0000 | 0.0002 | 0.0005 | 0.0052 | 0.0314 | 0.0597 | 0.0456 | 0.0609 | 0.7964 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 703 | 330 | | 1517 | 7267 | 260.9 | 69.91 | 59.78 | 117.99 | 178 | 191 | 206 | 227 | 248 | 274 | 304 | 331 | 369 | 0.0860 | 625 | 1.115 | 107.79 | 38.05 | 1 | 0.1793 | 272 | 0.0105 | 1.72 | 4.763 | 0.5649 | 72953.0 | 21700000 | 6830000000 | 2240000000000 | 0.3508 | 0.2996 | 0.0016 | 0.0000 | 0.0031 | 0.0000 | 0.0062 | 0.0015 | 0.0171 | 0.0067 | 0.0715 | 0.0340 | 0.0964 | 0.0503 | 0.1026 | 0.0392 | 0.1291 | 0.0673 | 0.5723 | 0.8010 | 0.0010 | 0.0000 | 0.0019 | 0.0000 | 0.0019 | 0.0000 | 0.0057 | 0.0040 | 0.0306 | 0.0224 | 0.0373 | 0.0369 | 0.0335 | 0.0257 | 0.0450 | 0.0383 | 0.8431 | 0.8727 | 0.0025 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0061 | 0.0124 | 0.0549 | 0.0423 | 0.0610 | 0.0547 | 0.0549 | 0.0448 | 0.1220 | 0.0821 | 0.0854 | 0.7512 | 0.6159 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0337 | 0.0527 | 0.0366 | 0.0439 | 0.8228 | 7 | 8 | 9 | 10 | 11 | 15 | 28 | 57 | 188 | 0.1752 | 2.71 | 2.781 | 0.6871 | 17493.2 | 7830000 | 4090000000 | 2340000000000 | 0.4255 | 0.2007 | 0.0273 | 0.0043 | 0.0648 | 0.0086 | 0.1297 | 0.0114 | 0.2150 | 0.0643 | 0.2116 | 0.1186 | 0.1502 | 0.1686 | 0.1229 | 0.1429 | 0.0614 | 0.1629 | 0.0171 | 0.3186 | 0.0031 | 0.0010 | 0.0037 | 0.0021 | 0.0074 | 0.0026 | 0.0155 | 0.0129 | 0.0372 | 0.0290 | 0.0440 | 0.0403 | 0.0415 | 0.0445 | 0.0551 | 0.0672 | 0.7926 | 0.8004 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0023 | 0.0024 | 0.0053 | 0.0097 | 0.0371 | 0.0308 | 0.0393 | 0.0559 | 0.0446 | 0.0454 | 0.0598 | 0.0608 | 0.8086 | 0.7950 | 0.0000 | 0.0021 | 0.0049 | 0.0119 | 0.0295 | 0.0372 | 0.0400 | 0.0534 | 0.8209 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 623 | 128 | | 5953 | 11599 | 530.3 | 117.08 | 264.39 | 415.53 | 392 | 428 | 458 | 485 | 513 | 546 | 584 | 630 | 696 | 0.0813 | 943 | 0.967 | 130.08 | 35.78 | 1 | 0.0519 | 309 | 0.0004 | 120.83 | 7.914 | 0.1104 | 294936.0 | 172000000 | 105000000000 | 66500000000000 | 0.4302 | 0.2128 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0059 | 0.0004 | 0.0185 | 0.0013 | 0.0765 | 0.0215 | 0.1506 | 0.0396 | 0.1458 | 0.0420 | 0.1956 | 0.0637 | 0.4064 | 0.8314 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0035 | 0.0000 | 0.0076 | 0.0003 | 0.0384 | 0.0137 | 0.0657 | 0.0215 | 0.0657 | 0.0178 | 0.0966 | 0.0280 | 0.7218 | 0.9187 | 0.0044 | 0.0061 | 0.0000 | 0.0214 | 0.0142 | 0.0428 | 0.0567 | 0.1284 | 0.1258 | 0.1743 | 0.1709 | 0.2110 | 0.1116 | 0.1376 | 0.1515 | 0.1407 | 0.3649 | 0.1376 | 0.0015 | 0.0015 | 0.0083 | 0.0326 | 0.0701 | 0.1227 | 0.0848 | 0.1148 | 0.5638 | 9 | 12 | 15 | 20 | 32 | 87 | 235 | 532 | 918 | 0.0999 | 84.61 | 5.018 | 0.5316 | 242548.0 | 294000000 | 414000000000 | 650000000000000 | 0.4380 | 0.2212 | 0.0713 | 0.0000 | 0.2240 | 0.0143 | 0.2261 | 0.1554 | 0.1344 | 0.1964 | 0.1303 | 0.1954 | 0.0876 | 0.1573 | 0.0448 | 0.0925 | 0.0407 | 0.0944 | 0.0407 | 0.0944 | 0.0006 | 0.0000 | 0.0003 | 0.0013 | 0.0014 | 0.0020 | 0.0089 | 0.0075 | 0.0371 | 0.0362 | 0.0674 | 0.0619 | 0.0438 | 0.0415 | 0.0726 | 0.0714 | 0.7680 | 0.7782 | 0.0006 | 0.0000 | 0.0000 | 0.0007 | 0.0013 | 0.0014 | 0.0055 | 0.0051 | 0.0375 | 0.0471 | 0.0789 | 0.0792 | 0.0465 | 0.0567 | 0.0818 | 0.0857 | 0.7478 | 0.7240 | 0.0003 | 0.0030 | 0.0021 | 0.0087 | 0.0382 | 0.0659 | 0.0454 | 0.0728 | 0.7636 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1191 | 273 | | 5225 | 11025 | 340.7 | 62.23 | 307.66 | 490.68 | 248 | 283 | 309 | 330 | 349 | 367 | 381 | 396 | 416 | 0.0786 | 867 | 0.925 | 79.06 | 24.04 | 4 | 0.0404 | 211 | 0.0014 | 23.53 | 6.846 | 0.2524 | 119949.0 | 43400000 | 16100000000 | 6080000000000 | 0.4363 | 0.2015 | 0.0005 | 0.0000 | 0.0024 | 0.0000 | 0.0052 | 0.0004 | 0.0144 | 0.0012 | 0.0415 | 0.0155 | 0.0735 | 0.0306 | 0.0749 | 0.0196 | 0.1045 | 0.0333 | 0.6830 | 0.8994 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0014 | 0.0004 | 0.0046 | 0.0012 | 0.0191 | 0.0153 | 0.0353 | 0.0304 | 0.0290 | 0.0163 | 0.0376 | 0.0273 | 0.8719 | 0.9093 | 0.0076 | 0.0000 | 0.0291 | 1.0000 | 0.0443 | 0.0000 | 0.0581 | 0.0000 | 0.1407 | 0.0000 | 0.1361 | 0.0000 | 0.1300 | 0.0000 | 0.1529 | 0.0000 | 0.3012 | 0.0000 | 0.0007 | 0.0021 | 0.0070 | 0.0115 | 0.0369 | 0.0518 | 0.0539 | 0.0869 | 0.7493 | 8 | 10 | 12 | 16 | 25 | 61 | 277 | 673 | 1103 | 0.0635 | 24.60 | 4.331 | 0.4441 | 335399.0 | 461000000 | 722000000000 | 1.24E+15 | 0.5061 | 0.1164 | 0.0746 | 0.0000 | 0.2293 | 0.0218 | 0.2541 | 0.1592 | 0.1602 | 0.1687 | 0.1409 | 0.2082 | 0.0829 | 0.1891 | 0.0304 | 0.0898 | 0.0193 | 0.0939 | 0.0083 | 0.0694 | 0.0000 | 0.0000 | 0.0006 | 0.0006 | 0.0038 | 0.0011 | 0.0065 | 0.0047 | 0.0332 | 0.0356 | 0.0632 | 0.0601 | 0.0397 | 0.0361 | 0.0585 | 0.0593 | 0.7947 | 0.8025 | 0.0003 | 0.0003 | 0.0007 | 0.0003 | 0.0023 | 0.0017 | 0.0056 | 0.0055 | 0.0391 | 0.0464 | 0.0687 | 0.0695 | 0.0444 | 0.0488 | 0.0736 | 0.0768 | 0.7653 | 0.7506 | 0.0003 | 0.0012 | 0.0016 | 0.0068 | 0.0346 | 0.0626 | 0.0392 | 0.0688 | 0.7849 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 740 | 703 | | 8862 | 18824 | 530.1 | 80.43 | 114.15 | 251.56 | 421 | 467 | 496 | 517 | 535 | 553 | 573 | 598 | 631 | 0.0548 | 1032 | 0.545 | 114.22 | 22.67 | 5 | 0.0372 | 330 | 0.0009 | 38.41 | 7.314 | 0.2073 | 287452.0 | 159000000 | 89500000000 | 51200000000000 | 0.4491 | 0.2025 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0007 | 0.0001 | 0.0056 | 0.0007 | 0.0282 | 0.0139 | 0.0564 | 0.0200 | 0.0512 | 0.0144 | 0.0715 | 0.0211 | 0.7858 | 0.9298 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0016 | 0.0007 | 0.0179 | 0.0139 | 0.0306 | 0.0200 | 0.0252 | 0.0144 | 0.0335 | 0.0202 | 0.8913 | 0.9307 | 0.0075 | 1.0000 | 0.0188 | 0.0000 | 0.0225 | 0.0000 | 0.0476 | 0.0000 | 0.1164 | 0.0000 | 0.1640 | 0.0000 | 0.1014 | 0.0000 | 0.1502 | 0.0000 | 0.3717 | 0.0000 | 0.0006 | 0.0036 | 0.0074 | 0.0181 | 0.0434 | 0.0613 | 0.0734 | 0.0863 | 0.7059 | 9 | 10 | 12 | 13 | 15 | 20 | 38 | 121 | 352 | 0.1429 | 9.00 | 3.049 | 0.5952 | 76308.2 | 79500000 | 99600000000 | 139000000000000 | 0.5235 | 0.1294 | 0.0259 | 0.0023 | 0.0761 | 0.0164 | 0.2120 | 0.0561 | 0.1942 | 0.0865 | 0.2006 | 0.1645 | 0.1003 | 0.2050 | 0.1036 | 0.1458 | 0.0631 | 0.1341 | 0.0243 | 0.1894 | 0.0000 | 0.0004 | 0.0002 | 0.0004 | 0.0012 | 0.0011 | 0.0067 | 0.0072 | 0.0396 | 0.0383 | 0.0538 | 0.0475 | 0.0401 | 0.0385 | 0.0569 | 0.0591 | 0.8015 | 0.8073 | 0.0003 | 0.0000 | 0.0006 | 0.0006 | 0.0017 | 0.0021 | 0.0056 | 0.0079 | 0.0476 | 0.0539 | 0.0673 | 0.0667 | 0.0437 | 0.0521 | 0.0707 | 0.0758 | 0.7625 | 0.7409 | 0.0000 | 0.0005 | 0.0016 | 0.0065 | 0.0428 | 0.0586 | 0.0418 | 0.0664 | 0.7819 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 779 | 704 | | 5803 | 19960 | 372.2 | 94.00 | 225.74 | 412.23 | 264 | 293 | 318 | 338 | 360 | 380 | 408 | 444 | 501 | 0.0479 | 957 | 1.184 | 131.46 | 56.92 | 1 | 0.0622 | 361 | 0.0010 | 43.53 | 7.206 | 0.1938 | 147377.0 | 62100000 | 27800000000 | 13200000000000 | 0.4343 | 0.2158 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0085 | 0.0004 | 0.0188 | 0.0023 | 0.0689 | 0.0252 | 0.1544 | 0.0502 | 0.1354 | 0.0473 | 0.1582 | 0.0622 | 0.4544 | 0.8124 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0015 | 0.0000 | 0.0071 | 0.0011 | 0.0331 | 0.0145 | 0.0767 | 0.0294 | 0.0663 | 0.0230 | 0.0802 | 0.0308 | 0.7347 | 0.9013 | 0.0000 | 0.0044 | 0.0062 | 0.0066 | 0.0213 | 0.0022 | 0.0364 | 0.0744 | 0.1058 | 0.1510 | 0.1538 | 0.1707 | 0.0809 | 0.1204 | 0.1200 | 0.1554 | 0.4756 | 0.3151 | 0.0020 | 0.0016 | 0.0110 | 0.0292 | 0.0817 | 0.1310 | 0.0781 | 0.1097 | 0.5558 | 8 | 10 | 11 | 13 | 15 | 26 | 121 | 400 | 845 | 0.2506 | 60.02 | 4.037 | 0.6340 | 220884.0 | 291000000 | 452000000000 | 796000000000000 | 0.4139 | 0.2037 | 0.0722 | 0.0028 | 0.2071 | 0.0270 | 0.2425 | 0.1555 | 0.1403 | 0.1634 | 0.1104 | 0.1811 | 0.0872 | 0.1783 | 0.0490 | 0.0909 | 0.0504 | 0.0831 | 0.0409 | 0.1179 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0007 | 0.0062 | 0.0044 | 0.0375 | 0.0329 | 0.0543 | 0.0543 | 0.0439 | 0.0317 | 0.0639 | 0.0529 | 0.7941 | 0.8231 | 0.0002 | 0.0000 | 0.0008 | 0.0011 | 0.0008 | 0.0013 | 0.0057 | 0.0067 | 0.0481 | 0.0528 | 0.0740 | 0.0799 | 0.0481 | 0.0528 | 0.0838 | 0.0860 | 0.7384 | 0.7192 | 0.0000 | 0.0004 | 0.0002 | 0.0082 | 0.0430 | 0.0638 | 0.0522 | 0.0724 | 0.7598 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 708 | 397 | | 15447 | 27394 | 562.4 | 113.78 | 118.30 | 212.73 | 394 | 458 | 507 | 542 | 576 | 606 | 636 | 667 | 703 | 0.0495 | 1356 | 0.896 | 108.19 | 30.00 | 3 | 0.0188 | 291 | 0.0006 | 29.72 | 7.605 | 0.2191 | 329218.0 | 199000000 | 124000000000 | 78600000000000 | 0.3988 | 0.2308 | 0.0014 | 0.0000 | 0.0019 | 0.0001 | 0.0040 | 0.0004 | 0.0105 | 0.0011 | 0.0269 | 0.0087 | 0.0473 | 0.0169 | 0.0485 | 0.0102 | 0.0672 | 0.0157 | 0.7922 | 0.9469 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0001 | 0.0023 | 0.0010 | 0.0107 | 0.0080 | 0.0188 | 0.0166 | 0.0160 | 0.0091 | 0.0204 | 0.0143 | 0.9310 | 0.9510 | 0.0029 | 0.0000 | 0.0095 | 0.0179 | 0.0147 | 0.0536 | 0.0297 | 0.1607 | 0.0612 | 0.1250 | 0.0718 | 0.1071 | 0.0872 | 0.2500 | 0.1213 | 0.1071 | 0.6015 | 0.1786 | 0.0008 | 0.0010 | 0.0032 | 0.0069 | 0.0226 | 0.0401 | 0.0411 | 0.0534 | 0.8309 | 7 | 9 | 10 | 11 | 12 | 15 | 40 | 206 | 467 | 0.3132 | 20.18 | 3.462 | 0.7115 | 59247.2 | 38200000 | 27600000000 | 21600000000000 | 0.5023 | 0.1444 | 0.0436 | 0.0036 | 0.1336 | 0.0128 | 0.2377 | 0.1026 | 0.1744 | 0.1354 | 0.1547 | 0.1810 | 0.1069 | 0.1882 | 0.0675 | 0.1055 | 0.0520 | 0.1119 | 0.0295 | 0.1589 | 0.0000 | 0.0003 | 0.0003 | 0.0004 | 0.0010 | 0.0004 | 0.0058 | 0.0038 | 0.0203 | 0.0189 | 0.0418 | 0.0353 | 0.0301 | 0.0220 | 0.0517 | 0.0418 | 0.8491 | 0.8771 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0058 | 0.0079 | 0.0263 | 0.0302 | 0.0558 | 0.0631 | 0.0452 | 0.0492 | 0.0622 | 0.0705 | 0.8037 | 0.7782 | 0.0000 | 0.0000 | 0.0006 | 0.0049 | 0.0263 | 0.0486 | 0.0405 | 0.0571 | 0.8221 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 307 | 284 | | 4454 | 15705 | 541.8 | 126.10 | 114.66 | 191.51 | 395 | 434 | 463 | 491 | 521 | 551 | 591 | 651 | 728 | 0.0554 | 870 | 1.060 | 102.88 | 27.59 | 2 | 0.0534 | 238 | 0.0008 | 82.33 | 7.369 | 0.1665 | 309466.0 | 186000000 | 118000000000 | 78000000000000 | 0.4066 | 0.2345 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0097 | 0.0005 | 0.0157 | 0.0027 | 0.0737 | 0.0261 | 0.1377 | 0.0438 | 0.1448 | 0.0443 | 0.1534 | 0.0597 | 0.4611 | 0.8229 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0056 | 0.0002 | 0.0407 | 0.0161 | 0.0709 | 0.0258 | 0.0709 | 0.0192 | 0.0895 | 0.0269 | 0.7210 | 0.9117 | 0.0022 | 0.0032 | 0.0000 | 0.0160 | 0.0078 | 0.0415 | 0.0526 | 0.0927 | 0.0973 | 0.1629 | 0.1353 | 0.1502 | 0.0839 | 0.1086 | 0.1074 | 0.1438 | 0.5134 | 0.2812 | 0.0000 | 0.0031 | 0.0062 | 0.0333 | 0.0868 | 0.1149 | 0.1004 | 0.1108 | 0.5445 | 5 | 7 | 8 | 10 | 11 | 17 | 98 | 220 | 400 | 0.1818 | 28.75 | 4.115 | 0.6043 | 49820.4 | 29100000 | 19900000000 | 15300000000000 | 0.3528 | 0.2965 | 0.0222 | 0.0027 | 0.0974 | 0.0054 | 0.2530 | 0.0467 | 0.2085 | 0.0916 | 0.1880 | 0.2163 | 0.1333 | 0.2720 | 0.0496 | 0.1517 | 0.0222 | 0.1086 | 0.0256 | 0.1050 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0010 | 0.0002 | 0.0025 | 0.0028 | 0.0223 | 0.0206 | 0.0377 | 0.0307 | 0.0289 | 0.0256 | 0.0466 | 0.0365 | 0.8607 | 0.8834 | 0.0005 | 0.0003 | 0.0002 | 0.0005 | 0.0002 | 0.0005 | 0.0059 | 0.0071 | 0.0334 | 0.0374 | 0.0541 | 0.0695 | 0.0498 | 0.0450 | 0.0636 | 0.0730 | 0.7923 | 0.7666 | 0.0002 | 0.0000 | 0.0004 | 0.0042 | 0.0271 | 0.0491 | 0.0391 | 0.0560 | 0.8237 | ||
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 841 | 100 | | 7377 | 24941 | 386.3 | 96.75 | 88.88 | 190.82 | 262 | 298 | 330 | 360 | 385 | 408 | 433 | 466 | 515 | 0.0500 | 1246 | 0.563 | 94.76 | 26.17 | 2 | 0.0409 | 302 | 0.0008 | 47.55 | 7.415 | 0.1751 | 158588.0 | 68800000 | 31400000000 | 15000000000000 | 0.4311 | 0.2177 | 0.0002 | 0.0000 | 0.0031 | 0.0005 | 0.0070 | 0.0012 | 0.0283 | 0.0041 | 0.0813 | 0.0252 | 0.1505 | 0.0529 | 0.1401 | 0.0558 | 0.1607 | 0.0799 | 0.4286 | 0.7805 | 0.0000 | 0.0000 | 0.0011 | 0.0001 | 0.0023 | 0.0003 | 0.0099 | 0.0018 | 0.0340 | 0.0163 | 0.0593 | 0.0332 | 0.0508 | 0.0272 | 0.0661 | 0.0402 | 0.7764 | 0.8808 | 0.0040 | 0.0130 | 0.0066 | 0.0238 | 0.0139 | 0.0563 | 0.0615 | 0.0909 | 0.1315 | 0.1970 | 0.1606 | 0.1710 | 0.1269 | 0.1255 | 0.1401 | 0.1299 | 0.3549 | 0.1926 | 0.0005 | 0.0014 | 0.0043 | 0.0220 | 0.0674 | 0.1016 | 0.1003 | 0.1272 | 0.5753 | 4 | 5 | 7 | 8 | 10 | 12 | 18 | 103 | 322 | 0.1971 | 13.23 | 3.393 | 0.6457 | 44309.3 | 31100000 | 25500000000 | 23000000000000 | 0.4510 | 0.1554 | 0.0309 | 0.0028 | 0.1373 | 0.0130 | 0.2921 | 0.0763 | 0.2205 | 0.1516 | 0.1431 | 0.2140 | 0.0986 | 0.1898 | 0.0271 | 0.1395 | 0.0213 | 0.1116 | 0.0290 | 0.1014 | 0.0000 | 0.0003 | 0.0009 | 0.0005 | 0.0007 | 0.0016 | 0.0037 | 0.0063 | 0.0213 | 0.0191 | 0.0374 | 0.0318 | 0.0250 | 0.0278 | 0.0407 | 0.0377 | 0.8703 | 0.8748 | 0.0000 | 0.0002 | 0.0008 | 0.0004 | 0.0004 | 0.0019 | 0.0063 | 0.0064 | 0.0259 | 0.0282 | 0.0468 | 0.0526 | 0.0377 | 0.0404 | 0.0539 | 0.0614 | 0.8281 | 0.8084 | 0.0000 | 0.0004 | 0.0008 | 0.0042 | 0.0213 | 0.0423 | 0.0293 | 0.0477 | 0.8540 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 837 | 568 | | 3810 | 7691 | 452.3 | 131.47 | 221.21 | 376.57 | 230 | 356 | 426 | 457 | 480 | 503 | 528 | 553 | 586 | 0.0787 | 605 | 1.031 | 95.27 | 22.00 | 2 | 0.0559 | 213 | 0.0026 | 14.07 | 6.352 | 0.2995 | 221894.0 | 114000000 | 60800000000 | 33200000000000 | 0.3620 | 0.2645 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0029 | 0.0000 | 0.0119 | 0.0016 | 0.0530 | 0.0188 | 0.0759 | 0.0350 | 0.0740 | 0.0220 | 0.1050 | 0.0373 | 0.6765 | 0.8854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0145 | 0.0142 | 0.0290 | 0.0275 | 0.0145 | 0.0133 | 0.0244 | 0.0245 | 0.9162 | 0.9198 | 0.0021 | 0.0000 | 0.0054 | 0.0122 | 0.0171 | 0.0000 | 0.0289 | 0.0427 | 0.0567 | 0.1037 | 0.0739 | 0.0732 | 0.1017 | 0.1220 | 0.1210 | 0.0793 | 0.5931 | 0.5671 | 0.0004 | 0.0017 | 0.0021 | 0.0084 | 0.0261 | 0.0433 | 0.0517 | 0.0685 | 0.7977 | 9 | 14 | 18 | 23 | 32 | 56 | 165 | 387 | 734 | 0.0801 | 36.23 | 4.662 | 0.5714 | 190720.0 | 231000000 | 326000000000 | 505000000000000 | 0.5310 | 0.1283 | 0.0284 | 0.0000 | 0.2074 | 0.0058 | 0.3466 | 0.0902 | 0.1307 | 0.1645 | 0.1392 | 0.2082 | 0.0881 | 0.2475 | 0.0256 | 0.1092 | 0.0227 | 0.0975 | 0.0114 | 0.0771 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0008 | 0.0089 | 0.0041 | 0.0491 | 0.0454 | 0.0930 | 0.0827 | 0.0637 | 0.0458 | 0.0885 | 0.0827 | 0.6963 | 0.7387 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0052 | 0.0017 | 0.0063 | 0.0112 | 0.0645 | 0.0730 | 0.1096 | 0.1162 | 0.0739 | 0.0691 | 0.1070 | 0.1072 | 0.6329 | 0.6199 | 0.0000 | 0.0005 | 0.0029 | 0.0082 | 0.0629 | 0.0936 | 0.0739 | 0.0975 | 0.6606 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 149 | 240 | | 6671 | 12334 | 390.0 | 50.74 | 109.56 | 270.04 | 317 | 352 | 374 | 389 | 399 | 409 | 419 | 431 | 446 | 0.0712 | 878 | 0.700 | 125.40 | 29.61 | 3 | 0.0475 | 317 | 0.0019 | 22.81 | 6.624 | 0.2349 | 154695.0 | 62200000 | 25300000000 | 10400000000000 | 0.4580 | 0.1948 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0037 | 0.0003 | 0.0169 | 0.0112 | 0.0407 | 0.0210 | 0.0412 | 0.0134 | 0.0715 | 0.0187 | 0.8249 | 0.9354 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0023 | 0.0003 | 0.0133 | 0.0112 | 0.0316 | 0.0210 | 0.0235 | 0.0134 | 0.0319 | 0.0187 | 0.8969 | 0.9354 | 0.1176 | 0.0000 | 0.1438 | 0.0000 | 0.1373 | 0.0000 | 0.1830 | 0.0000 | 0.1111 | 0.0000 | 0.1569 | 0.0000 | 0.0261 | 0.0000 | 0.0523 | 0.0000 | 0.0719 | 0.0000 | 0.0020 | 0.0033 | 0.0091 | 0.0202 | 0.0463 | 0.0663 | 0.0825 | 0.1189 | 0.6514 | 9 | 11 | 12 | 14 | 15 | 18 | 24 | 59 | 344 | 0.2142 | 6.81 | 2.736 | 0.6641 | 84919.1 | 101000000 | 144000000000 | 229000000000000 | 0.5929 | 0.1077 | 0.0204 | 0.0068 | 0.0980 | 0.0068 | 0.1592 | 0.0492 | 0.1878 | 0.0881 | 0.2082 | 0.1593 | 0.1755 | 0.1864 | 0.1020 | 0.1203 | 0.0367 | 0.1661 | 0.0122 | 0.2169 | 0.0005 | 0.0017 | 0.0019 | 0.0004 | 0.0014 | 0.0034 | 0.0052 | 0.0085 | 0.0331 | 0.0296 | 0.0553 | 0.0525 | 0.0355 | 0.0407 | 0.0766 | 0.0805 | 0.7905 | 0.7827 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0021 | 0.0017 | 0.0064 | 0.0079 | 0.0380 | 0.0350 | 0.0545 | 0.0599 | 0.0401 | 0.0418 | 0.0866 | 0.0870 | 0.7722 | 0.7662 | 0.0000 | 0.0000 | 0.0020 | 0.0076 | 0.0289 | 0.0613 | 0.0370 | 0.0770 | 0.7863 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 621 | 832 | | 10045 | 16653 | 624.4 | 136.14 | 146.38 | 247.89 | 478 | 513 | 544 | 571 | 595 | 625 | 662 | 712 | 830 | 0.0671 | 1118 | 1.208 | 132.46 | 56.89 | 1 | 0.0353 | 355 | 0.0011 | 29.04 | 7.171 | 0.2381 | 408412.0 | 281000000 | 204000000000 | 157000000000000 | 0.4086 | 0.2413 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0023 | 0.0007 | 0.0125 | 0.0016 | 0.0328 | 0.0154 | 0.0584 | 0.0291 | 0.0670 | 0.0221 | 0.0956 | 0.0345 | 0.7297 | 0.8966 | 0.0005 | 0.0000 | 0.0006 | 0.0000 | 0.0014 | 0.0000 | 0.0072 | 0.0002 | 0.0161 | 0.0088 | 0.0293 | 0.0152 | 0.0349 | 0.0084 | 0.0505 | 0.0148 | 0.8595 | 0.9526 | 0.0006 | 0.0029 | 0.0069 | 0.0073 | 0.0075 | 0.0190 | 0.0162 | 0.0321 | 0.0643 | 0.1226 | 0.0899 | 0.1431 | 0.0762 | 0.1080 | 0.1043 | 0.1328 | 0.6340 | 0.4321 | 0.0025 | 0.0025 | 0.0069 | 0.0195 | 0.0468 | 0.0683 | 0.0678 | 0.0849 | 0.7009 | 4 | 5 | 6 | 8 | 10 | 19 | 116 | 297 | 537 | 0.1488 | 72.06 | 4.406 | 0.5290 | 82870.7 | 61800000 | 54900000000 | 56100000000000 | 0.4135 | 0.2138 | 0.0751 | 0.0057 | 0.2521 | 0.0378 | 0.2654 | 0.1946 | 0.1669 | 0.1626 | 0.1135 | 0.1847 | 0.0785 | 0.1782 | 0.0234 | 0.1043 | 0.0200 | 0.0796 | 0.0050 | 0.0525 | 0.0000 | 0.0004 | 0.0008 | 0.0011 | 0.0014 | 0.0009 | 0.0050 | 0.0058 | 0.0321 | 0.0227 | 0.0675 | 0.0676 | 0.0431 | 0.0353 | 0.0673 | 0.0584 | 0.7827 | 0.8076 | 0.0009 | 0.0002 | 0.0005 | 0.0005 | 0.0023 | 0.0017 | 0.0068 | 0.0076 | 0.0390 | 0.0463 | 0.0847 | 0.0926 | 0.0513 | 0.0638 | 0.0884 | 0.0938 | 0.7262 | 0.6935 | 0.0000 | 0.0006 | 0.0023 | 0.0088 | 0.0301 | 0.0818 | 0.0496 | 0.0716 | 0.7552 | ||
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 503 | 432 | | 11808 | 33332 | 318.9 | 77.36 | 142.89 | 210.03 | 224 | 252 | 274 | 294 | 313 | 332 | 354 | 382 | 421 | 0.0347 | 1158 | 1.075 | 96.88 | 32.00 | 1 | 0.0204 | 241 | 0.0011 | 35.28 | 7.136 | 0.2018 | 107664.0 | 38400000 | 14400000000 | 5670000000000 | 0.4385 | 0.2096 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0068 | 0.0004 | 0.0240 | 0.0021 | 0.0823 | 0.0190 | 0.1435 | 0.0483 | 0.1432 | 0.0507 | 0.1608 | 0.0696 | 0.4388 | 0.8100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0071 | 0.0012 | 0.0317 | 0.0115 | 0.0656 | 0.0250 | 0.0600 | 0.0226 | 0.0788 | 0.0331 | 0.7553 | 0.9064 | 0.0047 | 0.0040 | 0.0064 | 0.0162 | 0.0180 | 0.0324 | 0.0588 | 0.1309 | 0.1171 | 0.1646 | 0.1656 | 0.2146 | 0.1257 | 0.1242 | 0.1416 | 0.1026 | 0.3621 | 0.2105 | 0.0020 | 0.0023 | 0.0069 | 0.0236 | 0.0705 | 0.1235 | 0.0941 | 0.1163 | 0.5608 | 6 | 7 | 9 | 11 | 20 | 67 | 166 | 292 | 458 | 0.1413 | 28.98 | 4.701 | 0.5652 | 64528.1 | 40100000 | 31100000000 | 29500000000000 | 0.4198 | 0.2297 | 0.0409 | 0.0008 | 0.1490 | 0.0130 | 0.2877 | 0.0770 | 0.1876 | 0.1317 | 0.1496 | 0.1991 | 0.0863 | 0.2098 | 0.0489 | 0.1278 | 0.0334 | 0.1018 | 0.0167 | 0.1390 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0007 | 0.0046 | 0.0041 | 0.0332 | 0.0264 | 0.0586 | 0.0502 | 0.0443 | 0.0368 | 0.0677 | 0.0562 | 0.7904 | 0.8252 | 0.0000 | 0.0002 | 0.0003 | 0.0008 | 0.0015 | 0.0014 | 0.0069 | 0.0086 | 0.0446 | 0.0485 | 0.0792 | 0.0935 | 0.0610 | 0.0660 | 0.0897 | 0.0966 | 0.7168 | 0.6842 | 0.0000 | 0.0006 | 0.0008 | 0.0069 | 0.0372 | 0.0677 | 0.0539 | 0.0771 | 0.7557 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 401 | 465 | | 5688 | 21468 | 395.0 | 83.99 | 124.18 | 239.02 | 290 | 326 | 352 | 373 | 392 | 410 | 430 | 457 | 504 | 0.0522 | 1120 | 1.175 | 146.10 | 54.92 | 1 | 0.0647 | 368 | 0.0007 | 85.77 | 7.563 | 0.1400 | 163082.0 | 70200000 | 31500000000 | 14700000000000 | 0.4503 | 0.2076 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0036 | 0.0000 | 0.0145 | 0.0009 | 0.0614 | 0.0220 | 0.1338 | 0.0403 | 0.1196 | 0.0438 | 0.1527 | 0.0645 | 0.5131 | 0.8284 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0036 | 0.0004 | 0.0302 | 0.0151 | 0.0598 | 0.0258 | 0.0550 | 0.0211 | 0.0858 | 0.0337 | 0.7648 | 0.9040 | 0.0011 | 0.0168 | 0.0078 | 0.0294 | 0.0343 | 0.0546 | 0.0676 | 0.1723 | 0.1495 | 0.1765 | 0.2137 | 0.2185 | 0.0952 | 0.0840 | 0.1384 | 0.0840 | 0.2924 | 0.1639 | 0.0018 | 0.0025 | 0.0094 | 0.0305 | 0.0864 | 0.1409 | 0.1097 | 0.1543 | 0.4644 | 7 | 8 | 9 | 11 | 13 | 19 | 59 | 166 | 460 | 0.2326 | 28.31 | 3.763 | 0.6555 | 72548.9 | 59000000 | 55500000000 | 57500000000000 | 0.4057 | 0.2332 | 0.0627 | 0.0034 | 0.2304 | 0.0282 | 0.2413 | 0.1477 | 0.1242 | 0.1167 | 0.1363 | 0.1635 | 0.0893 | 0.1860 | 0.0555 | 0.1037 | 0.0483 | 0.1020 | 0.0121 | 0.1488 | 0.0000 | 0.0002 | 0.0002 | 0.0000 | 0.0007 | 0.0015 | 0.0069 | 0.0057 | 0.0502 | 0.0393 | 0.0700 | 0.0667 | 0.0470 | 0.0434 | 0.0722 | 0.0667 | 0.7528 | 0.7766 | 0.0000 | 0.0002 | 0.0007 | 0.0007 | 0.0015 | 0.0021 | 0.0071 | 0.0088 | 0.0563 | 0.0601 | 0.0801 | 0.0852 | 0.0541 | 0.0560 | 0.0781 | 0.0805 | 0.7221 | 0.7063 | 0.0000 | 0.0000 | 0.0024 | 0.0088 | 0.0529 | 0.0768 | 0.0489 | 0.0729 | 0.7373 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 461 | 123 | | 3257 | 6809 | 514.7 | 105.53 | 61.25 | 124.20 | 368 | 433 | 474 | 500 | 525 | 551 | 579 | 608 | 638 | 0.0824 | 561 | 0.766 | 87.00 | 16.03 | 3 | 0.0620 | 202 | 0.0010 | 52.75 | 7.148 | 0.1825 | 276060.0 | 153000000 | 86800000000 | 50400000000000 | 0.4286 | 0.2196 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0068 | 0.0000 | 0.0140 | 0.0013 | 0.0512 | 0.0198 | 0.0978 | 0.0406 | 0.0965 | 0.0227 | 0.1277 | 0.0373 | 0.6046 | 0.8782 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0029 | 0.0013 | 0.0220 | 0.0197 | 0.0447 | 0.0384 | 0.0293 | 0.0184 | 0.0411 | 0.0288 | 0.8596 | 0.8934 | 0.0077 | 0.1333 | 0.0173 | 0.1333 | 0.0288 | 0.0667 | 0.0865 | 0.1333 | 0.1404 | 0.2667 | 0.1442 | 0.1333 | 0.1231 | 0.0000 | 0.1654 | 0.1333 | 0.2865 | 0.0000 | 0.0011 | 0.0023 | 0.0079 | 0.0186 | 0.0514 | 0.0814 | 0.0729 | 0.1040 | 0.6605 | 7 | 9 | 11 | 12 | 14 | 19 | 31 | 56 | 175 | 0.1883 | 7.43 | 3.201 | 0.7374 | 19174.6 | 10600000 | 7360000000 | 5780000000000 | 0.4921 | 0.1647 | 0.0338 | 0.0142 | 0.0549 | 0.0252 | 0.0717 | 0.0377 | 0.0928 | 0.0660 | 0.1392 | 0.0849 | 0.1814 | 0.1289 | 0.2363 | 0.1321 | 0.1097 | 0.1525 | 0.0802 | 0.3585 | 0.0034 | 0.0045 | 0.0048 | 0.0078 | 0.0034 | 0.0111 | 0.0109 | 0.0167 | 0.0212 | 0.0279 | 0.0519 | 0.0507 | 0.0355 | 0.0423 | 0.0444 | 0.0591 | 0.8245 | 0.7799 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0016 | 0.0000 | 0.0073 | 0.0078 | 0.0334 | 0.0336 | 0.0465 | 0.0509 | 0.0302 | 0.0259 | 0.0522 | 0.0578 | 0.8280 | 0.8240 | 0.0008 | 0.0008 | 0.0046 | 0.0106 | 0.0236 | 0.0540 | 0.0274 | 0.0547 | 0.8237 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1044 | 317 | | 12277 | 27737 | 337.8 | 80.82 | 126.25 | 196.68 | 245 | 268 | 287 | 306 | 326 | 349 | 374 | 406 | 447 | 0.0408 | 1133 | 1.055 | 137.89 | 53.26 | 1 | 0.0307 | 377 | 0.0011 | 31.32 | 7.089 | 0.2146 | 120627.0 | 45500000 | 18100000000 | 7610000000000 | 0.4436 | 0.2108 | 0.0003 | 0.0000 | 0.0014 | 0.0000 | 0.0075 | 0.0005 | 0.0193 | 0.0028 | 0.0768 | 0.0156 | 0.1399 | 0.0382 | 0.1395 | 0.0401 | 0.1655 | 0.0606 | 0.4499 | 0.8421 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0066 | 0.0003 | 0.0331 | 0.0088 | 0.0616 | 0.0201 | 0.0593 | 0.0159 | 0.0849 | 0.0256 | 0.7518 | 0.9293 | 0.0008 | 0.0082 | 0.0036 | 0.0192 | 0.0097 | 0.0549 | 0.0449 | 0.1152 | 0.1237 | 0.1578 | 0.1556 | 0.1852 | 0.1144 | 0.1221 | 0.1516 | 0.1221 | 0.3957 | 0.2154 | 0.0007 | 0.0024 | 0.0049 | 0.0284 | 0.0649 | 0.1105 | 0.0822 | 0.1107 | 0.5952 | 5 | 7 | 8 | 10 | 13 | 46 | 142 | 252 | 404 | 0.0900 | 13.02 | 4.139 | 0.4903 | 54618.6 | 33500000 | 26000000000 | 23800000000000 | 0.3964 | 0.2554 | 0.0519 | 0.0030 | 0.2024 | 0.0144 | 0.3281 | 0.0926 | 0.1490 | 0.1590 | 0.1211 | 0.2328 | 0.0760 | 0.2176 | 0.0384 | 0.1206 | 0.0256 | 0.0893 | 0.0075 | 0.0708 | 0.0000 | 0.0000 | 0.0002 | 0.0003 | 0.0009 | 0.0006 | 0.0045 | 0.0028 | 0.0333 | 0.0259 | 0.0610 | 0.0514 | 0.0479 | 0.0383 | 0.0731 | 0.0617 | 0.7792 | 0.8190 | 0.0002 | 0.0001 | 0.0001 | 0.0012 | 0.0011 | 0.0016 | 0.0074 | 0.0108 | 0.0452 | 0.0500 | 0.0802 | 0.0994 | 0.0683 | 0.0688 | 0.0954 | 0.1041 | 0.7019 | 0.6639 | 0.0001 | 0.0001 | 0.0005 | 0.0061 | 0.0373 | 0.0712 | 0.0564 | 0.0847 | 0.7437 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 420 | 742 | | 10935 | 36965 | 570.5 | 116.52 | 204.39 | 357.85 | 434 | 472 | 502 | 530 | 557 | 586 | 619 | 663 | 727 | 0.0445 | 1646 | 1.010 | 102.55 | 38.05 | 2 | 0.0258 | 282 | 0.0006 | 81.76 | 7.769 | 0.1488 | 339006.0 | 210000000 | 136000000000 | 92000000000000 | 0.4191 | 0.2288 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0035 | 0.0003 | 0.0113 | 0.0011 | 0.0543 | 0.0126 | 0.1116 | 0.0285 | 0.1155 | 0.0282 | 0.1447 | 0.0456 | 0.5584 | 0.8837 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0039 | 0.0003 | 0.0256 | 0.0086 | 0.0516 | 0.0165 | 0.0554 | 0.0121 | 0.0712 | 0.0199 | 0.7907 | 0.9426 | 0.0034 | 0.0123 | 0.0069 | 0.0369 | 0.0195 | 0.0541 | 0.0653 | 0.1253 | 0.1146 | 0.1695 | 0.1725 | 0.1892 | 0.1135 | 0.0983 | 0.1358 | 0.1007 | 0.3685 | 0.2138 | 0.0006 | 0.0044 | 0.0105 | 0.0277 | 0.0720 | 0.1148 | 0.0938 | 0.1191 | 0.5571 | 6 | 8 | 9 | 11 | 14 | 35 | 134 | 381 | 754 | 0.1781 | 65.60 | 4.468 | 0.5873 | 169829.0 | 188000000 | 243000000000 | 352000000000000 | 0.4094 | 0.2312 | 0.1194 | 0.0037 | 0.3132 | 0.0514 | 0.3248 | 0.2365 | 0.1171 | 0.2139 | 0.0620 | 0.1913 | 0.0302 | 0.1403 | 0.0225 | 0.0740 | 0.0078 | 0.0503 | 0.0031 | 0.0385 | 0.0000 | 0.0000 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0066 | 0.0033 | 0.0399 | 0.0364 | 0.0767 | 0.0693 | 0.0521 | 0.0427 | 0.0787 | 0.0708 | 0.7456 | 0.7764 | 0.0000 | 0.0000 | 0.0001 | 0.0003 | 0.0010 | 0.0015 | 0.0075 | 0.0101 | 0.0502 | 0.0538 | 0.0946 | 0.1037 | 0.0644 | 0.0702 | 0.0978 | 0.1071 | 0.6844 | 0.6533 | 0.0000 | 0.0002 | 0.0006 | 0.0068 | 0.0462 | 0.0827 | 0.0597 | 0.0911 | 0.7127 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 792 | 805 | | 4919 | 8206 | 382.1 | 68.91 | 141.31 | 188.12 | 300 | 324 | 344 | 360 | 375 | 392 | 412 | 438 | 476 | 0.0898 | 737 | 1.029 | 141.51 | 47.89 | 1 | 0.0732 | 360 | 0.0011 | 37.46 | 7.089 | 0.1984 | 150764.0 | 61400000 | 25800000000 | 11200000000000 | 0.4301 | 0.2151 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0030 | 0.0000 | 0.0107 | 0.0015 | 0.0411 | 0.0153 | 0.0748 | 0.0283 | 0.0789 | 0.0233 | 0.1114 | 0.0344 | 0.6794 | 0.8971 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0016 | 0.0000 | 0.0041 | 0.0008 | 0.0202 | 0.0133 | 0.0357 | 0.0198 | 0.0359 | 0.0131 | 0.0538 | 0.0182 | 0.8484 | 0.9348 | 0.0014 | 0.0000 | 0.0043 | 0.0000 | 0.0216 | 0.0000 | 0.0620 | 0.0000 | 0.1037 | 0.0000 | 0.1527 | 0.0000 | 0.1081 | 0.0000 | 0.1326 | 0.0000 | 0.4135 | 0.0000 | 0.0022 | 0.0022 | 0.0118 | 0.0263 | 0.0679 | 0.1121 | 0.0937 | 0.1222 | 0.5617 | 17 | 22 | 29 | 36 | 53 | 94 | 149 | 244 | 370 | 0.0319 | 21.94 | 5.086 | 0.5347 | 55351.4 | 34100000 | 26500000000 | 23500000000000 | 0.4596 | 0.1622 | 0.0237 | 0.0014 | 0.1379 | 0.0121 | 0.2020 | 0.0752 | 0.1323 | 0.1079 | 0.1295 | 0.1526 | 0.1337 | 0.1923 | 0.0975 | 0.1214 | 0.0641 | 0.1008 | 0.0794 | 0.2363 | 0.0000 | 0.0000 | 0.0010 | 0.0003 | 0.0007 | 0.0012 | 0.0104 | 0.0064 | 0.0542 | 0.0436 | 0.0808 | 0.0753 | 0.0636 | 0.0516 | 0.0855 | 0.0680 | 0.7037 | 0.7537 | 0.0013 | 0.0000 | 0.0000 | 0.0010 | 0.0018 | 0.0015 | 0.0075 | 0.0185 | 0.0755 | 0.0713 | 0.1132 | 0.1307 | 0.0644 | 0.0723 | 0.1012 | 0.1142 | 0.6350 | 0.5905 | 0.0004 | 0.0008 | 0.0016 | 0.0117 | 0.0600 | 0.1028 | 0.0631 | 0.0919 | 0.6678 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1107 | 725 | | 3073 | 3969 | 338.0 | 79.28 | 111.41 | 132.27 | 234 | 267 | 290 | 314 | 335 | 356 | 378 | 405 | 441 | 0.1217 | 483 | 1.226 | 141.20 | 63.63 | 1 | 0.1276 | 392 | 0.0012 | 36.06 | 6.918 | 0.1908 | 120541.0 | 45200000 | 17700000000 | 7230000000000 | 0.4322 | 0.2106 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0044 | 0.0000 | 0.0183 | 0.0046 | 0.0759 | 0.0201 | 0.1506 | 0.0466 | 0.1440 | 0.0508 | 0.1849 | 0.0756 | 0.4219 | 0.8019 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0017 | 0.0000 | 0.0079 | 0.0033 | 0.0277 | 0.0147 | 0.0513 | 0.0287 | 0.0484 | 0.0184 | 0.0778 | 0.0277 | 0.7854 | 0.9068 | 0.0033 | 0.0248 | 0.0082 | 0.0124 | 0.0131 | 0.0559 | 0.0784 | 0.1801 | 0.1373 | 0.2236 | 0.2124 | 0.1677 | 0.1193 | 0.1242 | 0.1373 | 0.1118 | 0.2909 | 0.0994 | 0.0007 | 0.0013 | 0.0060 | 0.0219 | 0.0672 | 0.1203 | 0.1110 | 0.1356 | 0.5359 | 12 | 23 | 35 | 48 | 64 | 85 | 116 | 178 | 274 | 0.0254 | 11.05 | 4.985 | 0.5393 | 29902.0 | 13200000 | 7610000000 | 5130000000000 | 0.5025 | 0.1307 | 0.0142 | 0.0010 | 0.0548 | 0.0120 | 0.1258 | 0.0239 | 0.1400 | 0.0658 | 0.1826 | 0.1396 | 0.1562 | 0.1854 | 0.1014 | 0.1206 | 0.1055 | 0.1356 | 0.1197 | 0.3161 | 0.0006 | 0.0000 | 0.0000 | 0.0026 | 0.0019 | 0.0036 | 0.0130 | 0.0104 | 0.0467 | 0.0410 | 0.0746 | 0.0607 | 0.0655 | 0.0524 | 0.0966 | 0.0841 | 0.7010 | 0.7451 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0038 | 0.0043 | 0.0076 | 0.0152 | 0.0725 | 0.0769 | 0.0925 | 0.1073 | 0.0620 | 0.0921 | 0.1115 | 0.1138 | 0.6501 | 0.5894 | 0.0024 | 0.0016 | 0.0041 | 0.0114 | 0.0571 | 0.0702 | 0.0637 | 0.0980 | 0.6914 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 758 | 118 | | 3722 | 7678 | 368.8 | 182.51 | 164.24 | 272.94 | 145 | 178 | 217 | 266 | 351 | 446 | 510 | 563 | 614 | 0.0847 | 650 | 1.108 | 87.24 | 31.58 | 2 | 0.0623 | 232 | 0.0018 | 10.54 | 6.623 | 0.3115 | 169332.0 | 88000000 | 48900000000 | 28300000000000 | 0.2899 | 0.3386 | 0.0000 | 0.0007 | 0.0000 | 0.0027 | 0.0086 | 0.0047 | 0.0310 | 0.0167 | 0.1480 | 0.0670 | 0.2220 | 0.0965 | 0.1463 | 0.0810 | 0.1911 | 0.1186 | 0.2530 | 0.6122 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0010 | 0.0020 | 0.0029 | 0.0035 | 0.0201 | 0.0203 | 0.0315 | 0.0250 | 0.0220 | 0.0238 | 0.0382 | 0.0355 | 0.8844 | 0.8892 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0066 | 0.0149 | 0.0238 | 0.0411 | 0.0416 | 0.0747 | 0.0350 | 0.0691 | 0.0430 | 0.0756 | 0.8500 | 0.7208 | 0.0000 | 0.0000 | 0.0006 | 0.0017 | 0.0251 | 0.0345 | 0.0239 | 0.0395 | 0.8747 | 12 | 17 | 22 | 28 | 43 | 72 | 114 | 240 | 499 | 0.0621 | 27.12 | 4.594 | 0.6002 | 101458.0 | 93500000 | 101000000000 | 118000000000000 | 0.3873 | 0.2579 | 0.0278 | 0.0021 | 0.0732 | 0.0103 | 0.1995 | 0.0372 | 0.1692 | 0.0702 | 0.1843 | 0.1569 | 0.1162 | 0.1610 | 0.0909 | 0.1352 | 0.0707 | 0.1197 | 0.0682 | 0.3075 | 0.0019 | 0.0000 | 0.0014 | 0.0028 | 0.0053 | 0.0035 | 0.0101 | 0.0102 | 0.0483 | 0.0501 | 0.0718 | 0.0654 | 0.0565 | 0.0556 | 0.0775 | 0.0832 | 0.7271 | 0.7292 | 0.0000 | 0.0006 | 0.0041 | 0.0006 | 0.0053 | 0.0026 | 0.0077 | 0.0057 | 0.0543 | 0.0529 | 0.0721 | 0.0861 | 0.0543 | 0.0529 | 0.0874 | 0.0848 | 0.7147 | 0.7136 | 0.0005 | 0.0027 | 0.0086 | 0.0065 | 0.0507 | 0.0706 | 0.0507 | 0.0841 | 0.7256 | ||
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1217 | 492 | | 4158 | 8748 | 478.3 | 77.87 | 112.81 | 236.09 | 376 | 414 | 441 | 464 | 483 | 499 | 516 | 535 | 574 | 0.0725 | 634 | 0.983 | 79.31 | 27.31 | 1 | 0.0536 | 223 | 0.0016 | 22.49 | 6.757 | 0.2408 | 234837.0 | 118000000 | 60800000000 | 31900000000000 | 0.3975 | 0.2479 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0070 | 0.0005 | 0.0263 | 0.0161 | 0.0444 | 0.0266 | 0.0456 | 0.0159 | 0.0702 | 0.0242 | 0.8058 | 0.9168 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0002 | 0.0174 | 0.0145 | 0.0277 | 0.0252 | 0.0261 | 0.0128 | 0.0397 | 0.0206 | 0.8859 | 0.9267 | 0.0048 | 0.0000 | 0.0048 | 0.0000 | 0.0096 | 0.0556 | 0.0264 | 0.0833 | 0.0769 | 0.1667 | 0.0817 | 0.1389 | 0.1082 | 0.1667 | 0.1034 | 0.1111 | 0.5841 | 0.2778 | 0.0014 | 0.0018 | 0.0063 | 0.0136 | 0.0407 | 0.0678 | 0.0691 | 0.0985 | 0.7010 | 5 | 7 | 8 | 9 | 10 | 12 | 22 | 146 | 413 | 0.1638 | 17.76 | 3.315 | 0.5824 | 68457.9 | 58700000 | 59900000000 | 68200000000000 | 0.3262 | 0.2943 | 0.0588 | 0.0025 | 0.2888 | 0.0296 | 0.2513 | 0.1605 | 0.1016 | 0.1951 | 0.1123 | 0.1975 | 0.0695 | 0.1383 | 0.1016 | 0.0864 | 0.0107 | 0.0963 | 0.0053 | 0.0938 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0005 | 0.0081 | 0.0076 | 0.0389 | 0.0360 | 0.0567 | 0.0536 | 0.0354 | 0.0337 | 0.0445 | 0.0469 | 0.8164 | 0.8208 | 0.0006 | 0.0006 | 0.0000 | 0.0012 | 0.0045 | 0.0041 | 0.0078 | 0.0088 | 0.0380 | 0.0364 | 0.0553 | 0.0634 | 0.0330 | 0.0346 | 0.0508 | 0.0511 | 0.8101 | 0.7999 | 0.0000 | 0.0000 | 0.0005 | 0.0123 | 0.0410 | 0.0511 | 0.0373 | 0.0453 | 0.8125 | ||
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1246 | 203 | | 5974 | 10831 | 309.6 | 60.88 | 229.94 | 346.15 | 229 | 256 | 278 | 295 | 310 | 324 | 340 | 361 | 389 | 0.0792 | 858 | 0.570 | 89.36 | 14.42 | 1 | 0.0336 | 201 | 0.0010 | 42.49 | 7.110 | 0.1903 | 99557.1 | 33100000 | 11400000000 | 4030000000000 | 0.4350 | 0.2143 | 0.0005 | 0.0000 | 0.0005 | 0.0003 | 0.0049 | 0.0003 | 0.0155 | 0.0019 | 0.0608 | 0.0167 | 0.1043 | 0.0263 | 0.1316 | 0.0288 | 0.1592 | 0.0436 | 0.5228 | 0.8820 | 0.0004 | 0.0000 | 0.0002 | 0.0003 | 0.0010 | 0.0003 | 0.0058 | 0.0014 | 0.0243 | 0.0127 | 0.0467 | 0.0199 | 0.0505 | 0.0136 | 0.0664 | 0.0216 | 0.8047 | 0.9302 | 0.0043 | 0.0274 | 0.0228 | 0.0479 | 0.0390 | 0.0548 | 0.1029 | 0.1644 | 0.1484 | 0.1986 | 0.1582 | 0.1712 | 0.1387 | 0.1164 | 0.1278 | 0.1370 | 0.2579 | 0.0822 | 0.0007 | 0.0027 | 0.0050 | 0.0219 | 0.0757 | 0.1286 | 0.1173 | 0.1591 | 0.4890 | 4 | 7 | 9 | 12 | 19 | 103 | 267 | 475 | 758 | 0.0830 | 58.23 | 4.859 | 0.4659 | 172683.0 | 171000000 | 200000000000 | 267000000000000 | 0.3514 | 0.2613 | 0.0254 | 0.0000 | 0.1404 | 0.0131 | 0.2860 | 0.0672 | 0.2014 | 0.1345 | 0.1726 | 0.1921 | 0.0660 | 0.2192 | 0.0609 | 0.1432 | 0.0220 | 0.1188 | 0.0254 | 0.1118 | 0.0000 | 0.0000 | 0.0003 | 0.0010 | 0.0008 | 0.0010 | 0.0074 | 0.0049 | 0.0296 | 0.0227 | 0.0565 | 0.0462 | 0.0486 | 0.0366 | 0.0600 | 0.0545 | 0.7969 | 0.8332 | 0.0003 | 0.0000 | 0.0003 | 0.0017 | 0.0022 | 0.0034 | 0.0078 | 0.0112 | 0.0441 | 0.0454 | 0.0789 | 0.0919 | 0.0582 | 0.0671 | 0.0851 | 0.0824 | 0.7230 | 0.6969 | 0.0006 | 0.0009 | 0.0017 | 0.0086 | 0.0356 | 0.0710 | 0.0529 | 0.0690 | 0.7597 |