High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 350 | 768 | 2148 | 7377 | 649.8 | 190.42 | 59.61 | 108.11 | 361 | 467 | 544 | 624 | 689 | 729 | 767 | 811 | 863 | 0.0729 | 538 | 0.439 | 61.06 | 9.22 | 3 | 0.0791 | 170 | 0.0009 | 72.75 | 7.161 | 0.1651 | 458473.0 | 344000000 | 270000000000 | 221000000000000 | 0.4160 | 0.2058 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0006 | 0.0291 | 0.0023 | 0.0824 | 0.0283 | 0.1568 | 0.0702 | 0.1075 | 0.0385 | 0.1397 | 0.0645 | 0.4794 | 0.7957 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0045 | 0.0016 | 0.0293 | 0.0240 | 0.0560 | 0.0464 | 0.0350 | 0.0235 | 0.0592 | 0.0427 | 0.8160 | 0.8617 | 0.0000 | 0.0094 | 0.0000 | 0.0283 | 0.0035 | 0.0189 | 0.0260 | 0.0566 | 0.0781 | 0.1415 | 0.1163 | 0.2264 | 0.0885 | 0.0472 | 0.1250 | 0.1038 | 0.5625 | 0.3679 | 0.0000 | 0.0000 | 0.0000 | 0.0091 | 0.0432 | 0.0639 | 0.0490 | 0.0763 | 0.7585 | 7 | 9 | 11 | 13 | 16 | 21 | 32 | 64 | 203 | 0.0746 | 10.49 | 3.983 | 0.6307 | 15239.4 | 6560000 | 3660000000 | 2420000000000 | 0.2920 | 0.3302 | 0.0000 | 0.0050 | 0.0655 | 0.0113 | 0.2143 | 0.0239 | 0.2292 | 0.0642 | 0.2054 | 0.1597 | 0.1429 | 0.2013 | 0.0774 | 0.1660 | 0.0506 | 0.1698 | 0.0149 | 0.1987 | 0.0000 | 0.0019 | 0.0017 | 0.0043 | 0.0040 | 0.0038 | 0.0115 | 0.0125 | 0.0340 | 0.0355 | 0.0530 | 0.0485 | 0.0363 | 0.0384 | 0.0594 | 0.0677 | 0.8000 | 0.7872 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0043 | 0.0031 | 0.0129 | 0.0109 | 0.0372 | 0.0427 | 0.0558 | 0.0637 | 0.0393 | 0.0365 | 0.0629 | 0.0637 | 0.7877 | 0.7793 | 0.0000 | 0.0000 | 0.0007 | 0.0170 | 0.0352 | 0.0483 | 0.0463 | 0.0614 | 0.7911 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 431 | 339 | 3943 | 10483 | 650.4 | 93.20 | 77.12 | 134.86 | 524 | 578 | 611 | 637 | 655 | 676 | 697 | 725 | 765 | 0.0630 | 660 | 1.066 | 99.30 | 32.65 | 1 | 0.0621 | 245 | 0.0013 | 29.21 | 6.926 | 0.2389 | 431670.0 | 292000000 | 201000000000 | 140000000000000 | 0.4337 | 0.2092 | 0.0006 | 0.0000 | 0.0003 | 0.0000 | 0.0012 | 0.0000 | 0.0043 | 0.0003 | 0.0239 | 0.0147 | 0.0347 | 0.0234 | 0.0340 | 0.0127 | 0.0534 | 0.0226 | 0.8476 | 0.9264 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0003 | 0.0148 | 0.0147 | 0.0235 | 0.0234 | 0.0179 | 0.0127 | 0.0277 | 0.0226 | 0.9140 | 0.9264 | 0.0065 | 0.0000 | 0.0065 | 0.0000 | 0.0226 | 0.0000 | 0.0355 | 0.0000 | 0.1000 | 0.0000 | 0.0871 | 0.0000 | 0.1065 | 0.0000 | 0.1290 | 0.0000 | 0.5065 | 0.0000 | 0.0000 | 0.0038 | 0.0072 | 0.0191 | 0.0401 | 0.0558 | 0.0615 | 0.0873 | 0.7252 | 6 | 8 | 9 | 11 | 14 | 22 | 53 | 125 | 238 | 0.1380 | 10.00 | 3.574 | 0.6077 | 24132.5 | 11700000 | 7110000000 | 4930000000000 | 0.4308 | 0.2239 | 0.0546 | 0.0060 | 0.1513 | 0.0313 | 0.2122 | 0.0625 | 0.1912 | 0.1159 | 0.1639 | 0.1915 | 0.1261 | 0.1935 | 0.0630 | 0.1381 | 0.0315 | 0.1190 | 0.0063 | 0.1421 | 0.0010 | 0.0000 | 0.0017 | 0.0015 | 0.0024 | 0.0033 | 0.0102 | 0.0118 | 0.0453 | 0.0386 | 0.0572 | 0.0477 | 0.0437 | 0.0443 | 0.0670 | 0.0641 | 0.7716 | 0.7887 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0020 | 0.0017 | 0.0113 | 0.0139 | 0.0577 | 0.0582 | 0.0658 | 0.0747 | 0.0516 | 0.0595 | 0.0791 | 0.0860 | 0.7313 | 0.7059 | 0.0004 | 0.0000 | 0.0015 | 0.0127 | 0.0470 | 0.0601 | 0.0548 | 0.0660 | 0.7576 | |||
MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 637 | 251 | 4831 | 6157 | 434.9 | 144.34 | 87.99 | 128.76 | 226 | 293 | 353 | 413 | 455 | 489 | 520 | 554 | 622 | 0.1176 | 724 | 0.741 | 143.63 | 44.91 | 2 | 0.0909 | 439 | 0.0009 | 28.38 | 7.266 | 0.2359 | 209951.0 | 109000000 | 59200000000 | 33500000000000 | 0.3927 | 0.2352 | 0.0015 | 0.0000 | 0.0035 | 0.0000 | 0.0050 | 0.0003 | 0.0179 | 0.0042 | 0.0601 | 0.0282 | 0.1118 | 0.0434 | 0.0860 | 0.0299 | 0.1143 | 0.0511 | 0.5999 | 0.8429 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0002 | 0.0023 | 0.0022 | 0.0216 | 0.0210 | 0.0347 | 0.0259 | 0.0213 | 0.0213 | 0.0361 | 0.0291 | 0.8835 | 0.9002 | 0.0007 | 0.0000 | 0.0035 | 0.0000 | 0.0084 | 0.0000 | 0.0169 | 0.0000 | 0.0443 | 0.0000 | 0.0718 | 0.0000 | 0.0577 | 0.0000 | 0.0809 | 0.0000 | 0.7157 | 1.0000 | 0.0000 | 0.0007 | 0.0011 | 0.0048 | 0.0257 | 0.0432 | 0.0313 | 0.0555 | 0.8375 | 9 | 11 | 13 | 18 | 26 | 42 | 87 | 147 | 262 | 0.1247 | 11.17 | 3.769 | 0.6386 | 24317.8 | 10200000 | 5220000000 | 3080000000000 | 0.5729 | 0.1008 | 0.0398 | 0.0089 | 0.1273 | 0.0316 | 0.1777 | 0.0671 | 0.1751 | 0.0886 | 0.1565 | 0.1696 | 0.1008 | 0.1810 | 0.0955 | 0.1405 | 0.0822 | 0.1329 | 0.0451 | 0.1797 | 0.0005 | 0.0004 | 0.0020 | 0.0027 | 0.0025 | 0.0027 | 0.0094 | 0.0093 | 0.0480 | 0.0409 | 0.0762 | 0.0721 | 0.0574 | 0.0503 | 0.0826 | 0.0730 | 0.7216 | 0.7486 | 0.0000 | 0.0007 | 0.0018 | 0.0000 | 0.0030 | 0.0048 | 0.0152 | 0.0213 | 0.0626 | 0.0810 | 0.1027 | 0.1071 | 0.0699 | 0.1009 | 0.1240 | 0.1263 | 0.6207 | 0.5580 | 0.0000 | 0.0005 | 0.0016 | 0.0114 | 0.0565 | 0.0864 | 0.0549 | 0.1010 | 0.6877 | |
MDA-MB-231 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 154 | 245 | 7441 | 18098 | 595.1 | 99.87 | 158.05 | 276.24 | 459 | 515 | 549 | 576 | 598 | 618 | 640 | 669 | 725 | 0.0530 | 960 | 0.791 | 112.90 | 27.89 | 2 | 0.0372 | 277 | 0.0011 | 26.39 | 7.165 | 0.2288 | 364116.0 | 229000000 | 147000000000 | 96900000000000 | 0.4475 | 0.1984 | 0.0002 | 0.0000 | 0.0007 | 0.0001 | 0.0016 | 0.0000 | 0.0053 | 0.0005 | 0.0258 | 0.0124 | 0.0455 | 0.0206 | 0.0458 | 0.0151 | 0.0692 | 0.0230 | 0.8059 | 0.9282 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0003 | 0.0163 | 0.0116 | 0.0267 | 0.0174 | 0.0252 | 0.0115 | 0.0358 | 0.0181 | 0.8938 | 0.9412 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0292 | 0.0000 | 0.0560 | 0.0000 | 0.0840 | 0.0000 | 0.0793 | 0.0000 | 0.1039 | 0.0000 | 0.6196 | 0.0000 | 0.0018 | 0.0036 | 0.0094 | 0.0214 | 0.0420 | 0.0641 | 0.0646 | 0.0876 | 0.7055 | 11 | 14 | 17 | 20 | 25 | 35 | 85 | 239 | 575 | 0.1535 | 16.74 | 4.037 | 0.6476 | 101285.0 | 90600000 | 95000000000 | 112000000000000 | 0.3437 | 0.2785 | 0.0470 | 0.0020 | 0.1678 | 0.0214 | 0.1893 | 0.0935 | 0.1530 | 0.1136 | 0.1732 | 0.1877 | 0.0980 | 0.1717 | 0.0779 | 0.1236 | 0.0671 | 0.1142 | 0.0268 | 0.1723 | 0.0002 | 0.0000 | 0.0008 | 0.0002 | 0.0008 | 0.0013 | 0.0102 | 0.0086 | 0.0376 | 0.0335 | 0.0599 | 0.0539 | 0.0436 | 0.0392 | 0.0626 | 0.0588 | 0.7843 | 0.8046 | 0.0000 | 0.0003 | 0.0012 | 0.0000 | 0.0042 | 0.0040 | 0.0138 | 0.0138 | 0.0413 | 0.0458 | 0.0655 | 0.0684 | 0.0487 | 0.0468 | 0.0667 | 0.0620 | 0.7586 | 0.7589 | 0.0002 | 0.0007 | 0.0023 | 0.0114 | 0.0416 | 0.0654 | 0.0444 | 0.0633 | 0.7707 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 665 | 315 | 3881 | 7921 | 606.2 | 94.41 | 68.43 | 170.19 | 472 | 541 | 568 | 588 | 606 | 629 | 660 | 694 | 726 | 0.0917 | 726 | 0.976 | 112.07 | 42.38 | 2 | 0.0825 | 320 | 0.0014 | 32.18 | 6.910 | 0.2353 | 376420.0 | 239000000 | 154000000000 | 101000000000000 | 0.4392 | 0.1933 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0052 | 0.0005 | 0.0345 | 0.0169 | 0.0495 | 0.0301 | 0.0505 | 0.0161 | 0.0697 | 0.0270 | 0.7890 | 0.9095 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0005 | 0.0212 | 0.0169 | 0.0256 | 0.0301 | 0.0206 | 0.0161 | 0.0317 | 0.0270 | 0.8986 | 0.9095 | 0.0054 | 0.0000 | 0.0161 | 0.0000 | 0.0215 | 0.0000 | 0.0538 | 0.0000 | 0.1048 | 0.0000 | 0.1532 | 0.0000 | 0.1183 | 0.0000 | 0.1263 | 0.0000 | 0.4005 | 0.0000 | 0.0031 | 0.0031 | 0.0097 | 0.0219 | 0.0429 | 0.0566 | 0.0536 | 0.0929 | 0.7163 | 5 | 6 | 7 | 9 | 10 | 11 | 14 | 30 | 209 | 0.1903 | 6.63 | 2.602 | 0.6219 | 33642.3 | 23500000 | 18600000000 | 16100000000000 | 0.5469 | 0.1234 | 0.0143 | 0.0118 | 0.2071 | 0.0059 | 0.2500 | 0.0710 | 0.2357 | 0.1154 | 0.2571 | 0.2308 | 0.0286 | 0.2337 | 0.0071 | 0.1834 | 0.0000 | 0.1065 | 0.0000 | 0.0414 | 0.0000 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0050 | 0.0119 | 0.0114 | 0.0500 | 0.0456 | 0.0738 | 0.0777 | 0.0484 | 0.0428 | 0.0745 | 0.0720 | 0.7407 | 0.7418 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0009 | 0.0089 | 0.0132 | 0.0526 | 0.0545 | 0.0847 | 0.0771 | 0.0455 | 0.0526 | 0.0794 | 0.0808 | 0.7279 | 0.7209 | 0.0000 | 0.0000 | 0.0017 | 0.0093 | 0.0499 | 0.0854 | 0.0448 | 0.0761 | 0.7327 | |||
MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 844 | 729 | 5195 | 6746 | 513.2 | 118.34 | 131.41 | 201.76 | 374 | 422 | 455 | 484 | 509 | 533 | 559 | 598 | 663 | 0.1269 | 856 | 1.179 | 136.50 | 52.00 | 4 | 0.0670 | 348 | 0.0006 | 81.67 | 7.590 | 0.1403 | 277409.0 | 157000000 | 93300000000 | 57800000000000 | 0.4641 | 0.1828 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0092 | 0.0002 | 0.0187 | 0.0015 | 0.0728 | 0.0317 | 0.1260 | 0.0589 | 0.1091 | 0.0502 | 0.1534 | 0.0757 | 0.5108 | 0.7819 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0037 | 0.0008 | 0.0387 | 0.0254 | 0.0701 | 0.0404 | 0.0576 | 0.0258 | 0.0831 | 0.0416 | 0.7456 | 0.8661 | 0.0059 | 0.0100 | 0.0118 | 0.0134 | 0.0178 | 0.0334 | 0.0675 | 0.1104 | 0.1349 | 0.1371 | 0.1527 | 0.1605 | 0.0982 | 0.1171 | 0.1396 | 0.1371 | 0.3716 | 0.2809 | 0.0012 | 0.0020 | 0.0083 | 0.0313 | 0.0944 | 0.1583 | 0.1035 | 0.1432 | 0.4578 | 7 | 9 | 11 | 15 | 30 | 63 | 128 | 229 | 416 | 0.1248 | 27.25 | 4.487 | 0.5729 | 57968.2 | 37400000 | 29800000000 | 27700000000000 | 0.6421 | 0.0717 | 0.0374 | 0.0045 | 0.1828 | 0.0269 | 0.3106 | 0.1256 | 0.1806 | 0.1469 | 0.1564 | 0.2096 | 0.0639 | 0.2096 | 0.0419 | 0.1188 | 0.0176 | 0.0953 | 0.0088 | 0.0628 | 0.0000 | 0.0004 | 0.0004 | 0.0024 | 0.0009 | 0.0028 | 0.0121 | 0.0108 | 0.0689 | 0.0667 | 0.1123 | 0.0895 | 0.0671 | 0.0667 | 0.0988 | 0.0927 | 0.6395 | 0.6681 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0028 | 0.0050 | 0.0213 | 0.0292 | 0.0786 | 0.0856 | 0.1296 | 0.1290 | 0.0836 | 0.0862 | 0.1072 | 0.1141 | 0.5758 | 0.5509 | 0.0000 | 0.0010 | 0.0035 | 0.0180 | 0.0721 | 0.1181 | 0.0756 | 0.1086 | 0.6031 | |
MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1083 | 712 | 14567 | 23345 | 228.3 | 65.80 | 245.84 | 294.83 | 149 | 171 | 189 | 204 | 221 | 238 | 259 | 283 | 318 | 0.0544 | 1269 | 0.975 | 95.05 | 27.31 | 2 | 0.0162 | 236 | 0.0009 | 39.78 | 7.247 | 0.1948 | 56452.3 | 15000000 | 4270000000 | 1290000000000 | 0.4024 | 0.2555 | 0.0004 | 0.0000 | 0.0033 | 0.0002 | 0.0132 | 0.0010 | 0.0356 | 0.0063 | 0.1124 | 0.0290 | 0.1854 | 0.0626 | 0.1649 | 0.0652 | 0.1702 | 0.0924 | 0.3145 | 0.7434 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0018 | 0.0001 | 0.0102 | 0.0020 | 0.0384 | 0.0138 | 0.0759 | 0.0319 | 0.0663 | 0.0284 | 0.0851 | 0.0426 | 0.7219 | 0.8812 | 0.0023 | 0.0036 | 0.0040 | 0.0136 | 0.0144 | 0.0300 | 0.0586 | 0.0886 | 0.1114 | 0.1671 | 0.1697 | 0.2064 | 0.1117 | 0.1207 | 0.1400 | 0.1486 | 0.3879 | 0.2214 | 0.0012 | 0.0012 | 0.0051 | 0.0274 | 0.0791 | 0.1243 | 0.1042 | 0.1238 | 0.5337 | 8 | 10 | 17 | 42 | 109 | 218 | 349 | 492 | 669 | 0.0408 | 47.90 | 5.810 | 0.3933 | 147362.0 | 116000000 | 111000000000 | 123000000000000 | 0.4697 | 0.1864 | 0.1067 | 0.0030 | 0.2767 | 0.0213 | 0.3109 | 0.2024 | 0.1380 | 0.1983 | 0.0764 | 0.2125 | 0.0525 | 0.1566 | 0.0183 | 0.0876 | 0.0165 | 0.0554 | 0.0040 | 0.0630 | 0.0002 | 0.0001 | 0.0000 | 0.0000 | 0.0009 | 0.0008 | 0.0096 | 0.0068 | 0.0596 | 0.0493 | 0.0934 | 0.0808 | 0.0646 | 0.0569 | 0.0998 | 0.0835 | 0.6719 | 0.7217 | 0.0000 | 0.0001 | 0.0005 | 0.0000 | 0.0016 | 0.0021 | 0.0167 | 0.0199 | 0.0781 | 0.0907 | 0.1165 | 0.1342 | 0.0867 | 0.0938 | 0.1227 | 0.1335 | 0.5771 | 0.5256 | 0.0000 | 0.0001 | 0.0009 | 0.0116 | 0.0678 | 0.1051 | 0.0737 | 0.1126 | 0.6282 | |
MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 533 | 682 | 7313 | 29998 | 383.9 | 96.67 | 156.93 | 277.72 | 269 | 302 | 327 | 350 | 372 | 397 | 429 | 467 | 513 | 0.0399 | 1198 | 1.208 | 132.80 | 56.82 | 1 | 0.0483 | 353 | 0.0008 | 42.70 | 7.362 | 0.1796 | 156719.0 | 67700000 | 30900000000 | 14700000000000 | 0.4294 | 0.2186 | 0.0000 | 0.0002 | 0.0019 | 0.0000 | 0.0056 | 0.0006 | 0.0223 | 0.0032 | 0.0776 | 0.0240 | 0.1395 | 0.0531 | 0.1380 | 0.0451 | 0.1584 | 0.0649 | 0.4567 | 0.8089 | 0.0000 | 0.0001 | 0.0011 | 0.0000 | 0.0023 | 0.0003 | 0.0074 | 0.0016 | 0.0342 | 0.0155 | 0.0598 | 0.0314 | 0.0600 | 0.0208 | 0.0798 | 0.0327 | 0.7556 | 0.8977 | 0.0032 | 0.0056 | 0.0051 | 0.0093 | 0.0051 | 0.0075 | 0.0329 | 0.0746 | 0.0981 | 0.1362 | 0.1253 | 0.2034 | 0.1101 | 0.1063 | 0.1380 | 0.1716 | 0.4823 | 0.2854 | 0.0003 | 0.0015 | 0.0075 | 0.0301 | 0.0733 | 0.1004 | 0.0869 | 0.1025 | 0.5975 | 8 | 9 | 11 | 12 | 15 | 25 | 92 | 285 | 569 | 0.2355 | 33.94 | 3.958 | 0.6313 | 101753.0 | 91200000 | 98600000000 | 124000000000000 | 0.4779 | 0.1557 | 0.1073 | 0.0081 | 0.3320 | 0.0585 | 0.3330 | 0.2590 | 0.1394 | 0.2001 | 0.0471 | 0.2020 | 0.0301 | 0.1388 | 0.0090 | 0.0741 | 0.0020 | 0.0371 | 0.0000 | 0.0223 | 0.0002 | 0.0004 | 0.0006 | 0.0011 | 0.0008 | 0.0010 | 0.0076 | 0.0093 | 0.0425 | 0.0390 | 0.0726 | 0.0654 | 0.0486 | 0.0443 | 0.0803 | 0.0682 | 0.7467 | 0.7711 | 0.0001 | 0.0001 | 0.0004 | 0.0000 | 0.0019 | 0.0013 | 0.0107 | 0.0116 | 0.0477 | 0.0518 | 0.0894 | 0.1012 | 0.0658 | 0.0667 | 0.0972 | 0.1078 | 0.6868 | 0.6595 | 0.0000 | 0.0005 | 0.0009 | 0.0099 | 0.0457 | 0.0788 | 0.0566 | 0.0902 | 0.7173 | |
MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 610 | 740 | 10995 | 21735 | 347.4 | 98.02 | 165.63 | 275.68 | 237 | 265 | 287 | 309 | 330 | 354 | 385 | 424 | 482 | 0.0543 | 1180 | 0.823 | 156.77 | 42.94 | 1 | 0.0379 | 417 | 0.0006 | 76.46 | 7.762 | 0.1421 | 130306.0 | 52800000 | 23000000000 | 10800000000000 | 0.4099 | 0.2391 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0050 | 0.0004 | 0.0293 | 0.0030 | 0.0976 | 0.0224 | 0.1934 | 0.0609 | 0.1532 | 0.0578 | 0.1697 | 0.0815 | 0.3511 | 0.7739 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0001 | 0.0100 | 0.0014 | 0.0366 | 0.0128 | 0.0819 | 0.0266 | 0.0642 | 0.0246 | 0.0880 | 0.0371 | 0.7185 | 0.8974 | 0.0021 | 0.0038 | 0.0037 | 0.0104 | 0.0099 | 0.0133 | 0.0489 | 0.0579 | 0.1039 | 0.1670 | 0.1691 | 0.2201 | 0.1158 | 0.0911 | 0.1404 | 0.1670 | 0.4064 | 0.2695 | 0.0002 | 0.0032 | 0.0077 | 0.0270 | 0.0753 | 0.1302 | 0.0823 | 0.1115 | 0.5626 | 7 | 9 | 11 | 13 | 23 | 59 | 139 | 282 | 558 | 0.1212 | 27.49 | 4.518 | 0.5579 | 103430.0 | 90600000 | 93300000000 | 107000000000000 | 0.5655 | 0.1379 | 0.0639 | 0.0036 | 0.1916 | 0.0216 | 0.2652 | 0.1161 | 0.1568 | 0.1490 | 0.1285 | 0.1970 | 0.0930 | 0.1954 | 0.0558 | 0.1189 | 0.0323 | 0.1029 | 0.0129 | 0.0953 | 0.0002 | 0.0003 | 0.0003 | 0.0003 | 0.0008 | 0.0007 | 0.0092 | 0.0067 | 0.0505 | 0.0462 | 0.0921 | 0.0768 | 0.0586 | 0.0549 | 0.0894 | 0.0845 | 0.6990 | 0.7296 | 0.0004 | 0.0002 | 0.0007 | 0.0000 | 0.0020 | 0.0010 | 0.0127 | 0.0148 | 0.0665 | 0.0758 | 0.1061 | 0.1131 | 0.0700 | 0.0705 | 0.1023 | 0.1056 | 0.6393 | 0.6190 | 0.0003 | 0.0007 | 0.0012 | 0.0100 | 0.0608 | 0.1027 | 0.0621 | 0.0993 | 0.6629 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1107 | 725 | 3073 | 3969 | 338.0 | 79.28 | 111.41 | 132.27 | 234 | 267 | 290 | 314 | 335 | 356 | 378 | 405 | 441 | 0.1217 | 483 | 1.226 | 141.20 | 63.63 | 1 | 0.1276 | 392 | 0.0012 | 36.06 | 6.918 | 0.1908 | 120541.0 | 45200000 | 17700000000 | 7230000000000 | 0.4322 | 0.2106 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0044 | 0.0000 | 0.0183 | 0.0046 | 0.0759 | 0.0201 | 0.1506 | 0.0466 | 0.1440 | 0.0508 | 0.1849 | 0.0756 | 0.4219 | 0.8019 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0017 | 0.0000 | 0.0079 | 0.0033 | 0.0277 | 0.0147 | 0.0513 | 0.0287 | 0.0484 | 0.0184 | 0.0778 | 0.0277 | 0.7854 | 0.9068 | 0.0033 | 0.0248 | 0.0082 | 0.0124 | 0.0131 | 0.0559 | 0.0784 | 0.1801 | 0.1373 | 0.2236 | 0.2124 | 0.1677 | 0.1193 | 0.1242 | 0.1373 | 0.1118 | 0.2909 | 0.0994 | 0.0007 | 0.0013 | 0.0060 | 0.0219 | 0.0672 | 0.1203 | 0.1110 | 0.1356 | 0.5359 | 12 | 23 | 35 | 48 | 64 | 85 | 116 | 178 | 274 | 0.0254 | 11.05 | 4.985 | 0.5393 | 29902.0 | 13200000 | 7610000000 | 5130000000000 | 0.5025 | 0.1307 | 0.0142 | 0.0010 | 0.0548 | 0.0120 | 0.1258 | 0.0239 | 0.1400 | 0.0658 | 0.1826 | 0.1396 | 0.1562 | 0.1854 | 0.1014 | 0.1206 | 0.1055 | 0.1356 | 0.1197 | 0.3161 | 0.0006 | 0.0000 | 0.0000 | 0.0026 | 0.0019 | 0.0036 | 0.0130 | 0.0104 | 0.0467 | 0.0410 | 0.0746 | 0.0607 | 0.0655 | 0.0524 | 0.0966 | 0.0841 | 0.7010 | 0.7451 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0038 | 0.0043 | 0.0076 | 0.0152 | 0.0725 | 0.0769 | 0.0925 | 0.1073 | 0.0620 | 0.0921 | 0.1115 | 0.1138 | 0.6501 | 0.5894 | 0.0024 | 0.0016 | 0.0041 | 0.0114 | 0.0571 | 0.0702 | 0.0637 | 0.0980 | 0.6914 | |
MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 209 | 861 | 543 | 4357 | 152.9 | 32.22 | 90.49 | 146.81 | 112 | 125 | 134 | 144 | 152 | 161 | 170 | 181 | 194 | 0.0925 | 403 | 1.074 | 82.81 | 25.61 | 1 | 0.3665 | 199 | 0.0040 | 21.07 | 5.680 | 0.2454 | 24410.0 | 4050000 | 697000000 | 124000000000 | 0.4295 | 0.2088 | 0.0000 | 0.0000 | 0.0029 | 0.0000 | 0.0029 | 0.0000 | 0.0632 | 0.0078 | 0.1523 | 0.0447 | 0.1638 | 0.0953 | 0.1868 | 0.0700 | 0.1782 | 0.1498 | 0.2500 | 0.6323 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0000 | 0.0000 | 0.0156 | 0.0075 | 0.0690 | 0.0413 | 0.0980 | 0.0732 | 0.0802 | 0.0450 | 0.1114 | 0.0994 | 0.6236 | 0.7336 | 0.0198 | 0.0000 | 0.0099 | 0.0000 | 0.0891 | 0.1053 | 0.1089 | 0.3684 | 0.1782 | 0.3684 | 0.1188 | 0.0526 | 0.1584 | 0.1053 | 0.1386 | 0.0000 | 0.1782 | 0.0000 | 0.0000 | 0.0075 | 0.0491 | 0.0340 | 0.1132 | 0.1208 | 0.1094 | 0.1245 | 0.4415 | 6 | 7 | 9 | 10 | 12 | 26 | 64 | 155 | 335 | 0.1505 | 5.85 | 3.608 | 0.6197 | 29737.3 | 12900000 | 6260000000 | 3270000000000 | 0.5075 | 0.1310 | 0.0714 | 0.0045 | 0.1939 | 0.0201 | 0.2041 | 0.0447 | 0.2857 | 0.1029 | 0.1276 | 0.2282 | 0.0867 | 0.2371 | 0.0255 | 0.1365 | 0.0051 | 0.1275 | 0.0000 | 0.0984 | 0.0016 | 0.0014 | 0.0008 | 0.0000 | 0.0016 | 0.0007 | 0.0195 | 0.0114 | 0.0568 | 0.0549 | 0.0860 | 0.0834 | 0.0543 | 0.0499 | 0.0933 | 0.0848 | 0.6861 | 0.7135 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0031 | 0.0145 | 0.0157 | 0.0685 | 0.0680 | 0.0858 | 0.0931 | 0.0559 | 0.0596 | 0.1022 | 0.1004 | 0.6702 | 0.6600 | 0.0009 | 0.0000 | 0.0027 | 0.0089 | 0.0608 | 0.0956 | 0.0536 | 0.0903 | 0.6872 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 937 | 413 | 5991 | 6903 | 259.1 | 63.26 | 108.57 | 152.78 | 186 | 207 | 223 | 238 | 250 | 265 | 282 | 304 | 342 | 0.1114 | 769 | 0.943 | 112.29 | 28.65 | 1 | 0.0444 | 266 | 0.0008 | 62.88 | 7.417 | 0.1517 | 71152.1 | 20700000 | 6420000000 | 2110000000000 | 0.4321 | 0.2113 | 0.0005 | 0.0000 | 0.0011 | 0.0002 | 0.0030 | 0.0004 | 0.0169 | 0.0024 | 0.0651 | 0.0200 | 0.1350 | 0.0503 | 0.1430 | 0.0444 | 0.1793 | 0.0657 | 0.4560 | 0.8167 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0017 | 0.0002 | 0.0065 | 0.0010 | 0.0301 | 0.0128 | 0.0639 | 0.0298 | 0.0612 | 0.0204 | 0.0850 | 0.0356 | 0.7507 | 0.9002 | 0.0047 | 0.0024 | 0.0084 | 0.0095 | 0.0196 | 0.0261 | 0.0673 | 0.0760 | 0.1047 | 0.1283 | 0.1551 | 0.1995 | 0.1075 | 0.1045 | 0.1299 | 0.1330 | 0.4028 | 0.3207 | 0.0008 | 0.0015 | 0.0094 | 0.0297 | 0.0884 | 0.1290 | 0.1027 | 0.1354 | 0.5032 | 11 | 13 | 15 | 17 | 26 | 49 | 103 | 211 | 341 | 0.0743 | 21.34 | 4.592 | 0.5689 | 35125.6 | 15800000 | 8350000000 | 5000000000000 | 0.6509 | 0.0801 | 0.1317 | 0.0068 | 0.3103 | 0.0476 | 0.2351 | 0.1766 | 0.1505 | 0.1929 | 0.0909 | 0.1984 | 0.0313 | 0.1508 | 0.0313 | 0.0761 | 0.0094 | 0.0788 | 0.0094 | 0.0720 | 0.0023 | 0.0020 | 0.0014 | 0.0020 | 0.0045 | 0.0024 | 0.0136 | 0.0129 | 0.0573 | 0.0488 | 0.0741 | 0.0815 | 0.0605 | 0.0521 | 0.1137 | 0.1013 | 0.6726 | 0.6969 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0023 | 0.0138 | 0.0166 | 0.0585 | 0.0603 | 0.0973 | 0.1194 | 0.0713 | 0.0758 | 0.1176 | 0.1361 | 0.6383 | 0.5896 | 0.0005 | 0.0020 | 0.0030 | 0.0114 | 0.0530 | 0.0956 | 0.0624 | 0.1115 | 0.6606 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 972 | 177 | 395 | 12546 | 117.2 | 19.48 | 22.21 | 93.56 | 93 | 98 | 104 | 109 | 113 | 121 | 128 | 137 | 146 | 0.0524 | 657 | 1.105 | 42.05 | 12.04 | 0 | 0.2380 | 94 | 0.0471 | 0.93 | 3.300 | 0.6696 | 14103.0 | 1740000 | 221000000 | 28700000000 | 0.3949 | 0.2407 | 0.0000 | 0.0000 | 0.0102 | 0.0000 | 0.0136 | 0.0000 | 0.0374 | 0.0127 | 0.0646 | 0.0433 | 0.1224 | 0.0738 | 0.1327 | 0.0585 | 0.1565 | 0.0916 | 0.4626 | 0.7201 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0085 | 0.0000 | 0.0254 | 0.0127 | 0.0366 | 0.0430 | 0.0732 | 0.0734 | 0.0704 | 0.0532 | 0.0789 | 0.0658 | 0.7042 | 0.7519 | 0.0000 | 0.0000 | 0.0164 | 1.0000 | 0.0492 | 0.0000 | 0.0820 | 0.0000 | 0.0984 | 0.0000 | 0.1639 | 0.0000 | 0.1148 | 0.0000 | 0.1967 | 0.0000 | 0.2787 | 0.0000 | 0.0055 | 0.0055 | 0.0000 | 0.0497 | 0.0552 | 0.0718 | 0.0939 | 0.0939 | 0.6243 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 14 | 0.1205 | 3.55 | 1.534 | 0.4274 | 9246.7 | 8900000 | 10500000000 | 13500000000000 | 0.4645 | 0.1926 | 0.0604 | 0.1758 | 0.1758 | 0.0687 | 0.2582 | 0.0929 | 0.3462 | 0.1414 | 0.1099 | 0.1980 | 0.0385 | 0.1737 | 0.0110 | 0.0747 | 0.0000 | 0.0485 | 0.0000 | 0.0263 | 0.0000 | 0.0672 | 0.0020 | 0.0227 | 0.0099 | 0.0180 | 0.0159 | 0.0164 | 0.0556 | 0.0469 | 0.0724 | 0.0618 | 0.0764 | 0.0641 | 0.1022 | 0.0821 | 0.6657 | 0.6208 | 0.0024 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0026 | 0.0182 | 0.0140 | 0.0654 | 0.0727 | 0.0956 | 0.0969 | 0.0690 | 0.0625 | 0.0920 | 0.0982 | 0.6550 | 0.6531 | 0.0000 | 0.0022 | 0.0065 | 0.0196 | 0.0577 | 0.0882 | 0.0719 | 0.0882 | 0.6656 | |
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 895 | 609 | 4883 | 16388 | 528.4 | 82.82 | 129.28 | 239.46 | 424 | 462 | 486 | 505 | 525 | 545 | 568 | 595 | 639 | 0.0616 | 1009 | 0.725 | 104.48 | 25.55 | 1 | 0.0555 | 271 | 0.0023 | 18.30 | 6.393 | 0.2729 | 286071.0 | 158000000 | 89700000000 | 51900000000000 | 0.4173 | 0.2298 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0054 | 0.0004 | 0.0293 | 0.0147 | 0.0673 | 0.0263 | 0.0671 | 0.0165 | 0.1041 | 0.0296 | 0.7248 | 0.9125 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0004 | 0.0181 | 0.0138 | 0.0331 | 0.0232 | 0.0342 | 0.0135 | 0.0512 | 0.0220 | 0.8611 | 0.9271 | 0.0036 | 0.0000 | 0.0018 | 0.0000 | 0.0309 | 0.0882 | 0.0436 | 0.2353 | 0.1291 | 0.2941 | 0.1673 | 0.0882 | 0.0800 | 0.1765 | 0.1436 | 0.0882 | 0.4000 | 0.0294 | 0.0013 | 0.0051 | 0.0131 | 0.0300 | 0.0656 | 0.1016 | 0.0863 | 0.1121 | 0.5849 | 7 | 9 | 10 | 11 | 13 | 18 | 55 | 222 | 459 | 0.2514 | 33.66 | 3.796 | 0.6421 | 74049.5 | 59100000 | 55800000000 | 58800000000000 | 0.5654 | 0.1070 | 0.1457 | 0.0103 | 0.2870 | 0.0432 | 0.3576 | 0.2613 | 0.1369 | 0.2469 | 0.0397 | 0.2171 | 0.0221 | 0.1235 | 0.0110 | 0.0463 | 0.0000 | 0.0267 | 0.0000 | 0.0247 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0009 | 0.0004 | 0.0085 | 0.0063 | 0.0461 | 0.0469 | 0.0811 | 0.0735 | 0.0507 | 0.0480 | 0.0726 | 0.0676 | 0.7401 | 0.7571 | 0.0000 | 0.0003 | 0.0005 | 0.0000 | 0.0013 | 0.0030 | 0.0108 | 0.0120 | 0.0569 | 0.0569 | 0.0857 | 0.0867 | 0.0607 | 0.0684 | 0.0810 | 0.0878 | 0.7031 | 0.6848 | 0.0000 | 0.0000 | 0.0005 | 0.0097 | 0.0508 | 0.0832 | 0.0557 | 0.0735 | 0.7266 | |
MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 820 | 689 | 340 | 1923 | 397.1 | 79.43 | 199.34 | 201.26 | 294 | 333 | 352 | 372 | 390 | 408 | 435 | 465 | 504 | 0.1394 | 268 | 1.182 | 145.07 | 47.10 | 3 | 1.0029 | 341 | 0.0036 | 115.51 | 5.687 | 0.1125 | 163958.0 | 70300000 | 31200000000 | 14300000000000 | 0.3965 | 0.2306 | 0.0000 | 0.0000 | 0.0174 | 0.0000 | 0.0217 | 0.0000 | 0.0957 | 0.0245 | 0.1478 | 0.0890 | 0.1913 | 0.1196 | 0.1783 | 0.0706 | 0.1043 | 0.1135 | 0.2435 | 0.5828 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0241 | 0.0118 | 0.1069 | 0.0737 | 0.1621 | 0.1121 | 0.1241 | 0.0619 | 0.1241 | 0.1003 | 0.4517 | 0.6401 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0500 | 0.2308 | 0.1333 | 0.0000 | 0.2000 | 0.3077 | 0.2167 | 0.1538 | 0.0833 | 0.1538 | 0.1500 | 0.1538 | 0.1667 | 0.0000 | 0.0000 | 0.0000 | 0.0189 | 0.0818 | 0.1635 | 0.2075 | 0.1258 | 0.1635 | 0.2390 | 20 | 36 | 64 | 93 | 120 | 173 | 254 | 366 | 476 | 0.0098 | 59.99 | 5.843 | 0.3632 | 80219.5 | 45700000 | 32800000000 | 28000000000000 | 0.5269 | 0.1237 | 0.0813 | 0.0000 | 0.2536 | 0.0321 | 0.3971 | 0.1514 | 0.1579 | 0.2041 | 0.0478 | 0.2110 | 0.0287 | 0.2064 | 0.0144 | 0.0940 | 0.0191 | 0.0550 | 0.0000 | 0.0459 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0012 | 0.0042 | 0.0135 | 0.0156 | 0.0800 | 0.0582 | 0.1441 | 0.1163 | 0.0985 | 0.0789 | 0.1195 | 0.1184 | 0.5431 | 0.6075 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0057 | 0.0332 | 0.0361 | 0.1144 | 0.1347 | 0.1841 | 0.1822 | 0.1061 | 0.1101 | 0.1426 | 0.1480 | 0.4179 | 0.3833 | 0.0000 | 0.0000 | 0.0000 | 0.0142 | 0.1095 | 0.1551 | 0.1053 | 0.1351 | 0.4808 | |
BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1055 | 275 | 6493 | 11263 | 218.6 | 48.26 | 203.76 | 248.93 | 160 | 175 | 188 | 202 | 213 | 228 | 242 | 260 | 284 | 0.0805 | 907 | 1.214 | 109.13 | 46.40 | 1 | 0.0445 | 289 | 0.0010 | 41.92 | 7.174 | 0.1818 | 50116.4 | 12000000 | 3010000000 | 787000000000 | 0.4497 | 0.2024 | 0.0008 | 0.0000 | 0.0015 | 0.0000 | 0.0071 | 0.0008 | 0.0185 | 0.0023 | 0.0843 | 0.0181 | 0.1430 | 0.0392 | 0.1440 | 0.0382 | 0.1793 | 0.0581 | 0.4215 | 0.8433 | 0.0004 | 0.0000 | 0.0010 | 0.0000 | 0.0033 | 0.0006 | 0.0078 | 0.0012 | 0.0341 | 0.0120 | 0.0614 | 0.0246 | 0.0581 | 0.0156 | 0.0872 | 0.0283 | 0.7468 | 0.9177 | 0.0041 | 0.0101 | 0.0139 | 0.0270 | 0.0204 | 0.0642 | 0.0736 | 0.1182 | 0.1177 | 0.1959 | 0.1586 | 0.1791 | 0.1267 | 0.1115 | 0.1415 | 0.1149 | 0.3434 | 0.1791 | 0.0013 | 0.0037 | 0.0043 | 0.0266 | 0.0817 | 0.1116 | 0.0986 | 0.1305 | 0.5418 | 15 | 19 | 27 | 46 | 82 | 147 | 253 | 388 | 594 | 0.0226 | 54.69 | 5.986 | 0.4245 | 103479.0 | 70800000 | 56800000000 | 51000000000000 | 0.5176 | 0.1383 | 0.0392 | 0.0017 | 0.1105 | 0.0111 | 0.2280 | 0.0589 | 0.2245 | 0.1100 | 0.1425 | 0.1800 | 0.1140 | 0.2156 | 0.0784 | 0.1367 | 0.0439 | 0.1144 | 0.0190 | 0.1717 | 0.0000 | 0.0004 | 0.0000 | 0.0006 | 0.0016 | 0.0012 | 0.0128 | 0.0072 | 0.0372 | 0.0364 | 0.0763 | 0.0706 | 0.0547 | 0.0455 | 0.0772 | 0.0701 | 0.7402 | 0.7678 | 0.0006 | 0.0007 | 0.0006 | 0.0000 | 0.0020 | 0.0030 | 0.0121 | 0.0115 | 0.0506 | 0.0603 | 0.0917 | 0.1121 | 0.0697 | 0.0752 | 0.0975 | 0.1124 | 0.6752 | 0.6248 | 0.0000 | 0.0005 | 0.0018 | 0.0083 | 0.0458 | 0.0871 | 0.0564 | 0.0843 | 0.7159 | |
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 442 | 641 | 7990 | 25118 | 501.3 | 88.04 | 166.84 | 265.28 | 388 | 427 | 453 | 476 | 498 | 523 | 548 | 577 | 617 | 0.0471 | 1183 | 1.180 | 95.02 | 43.97 | 2 | 0.0333 | 266 | 0.0018 | 18.67 | 6.558 | 0.2470 | 259095.0 | 138000000 | 75200000000 | 42100000000000 | 0.4349 | 0.2174 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0022 | 0.0004 | 0.0081 | 0.0004 | 0.0446 | 0.0106 | 0.0956 | 0.0227 | 0.1034 | 0.0182 | 0.1448 | 0.0317 | 0.6006 | 0.9161 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0003 | 0.0024 | 0.0004 | 0.0209 | 0.0097 | 0.0427 | 0.0195 | 0.0421 | 0.0112 | 0.0628 | 0.0166 | 0.8279 | 0.9424 | 0.0064 | 0.0682 | 0.0091 | 0.0455 | 0.0320 | 0.0795 | 0.0970 | 0.1591 | 0.1473 | 0.2045 | 0.1802 | 0.1591 | 0.1180 | 0.0795 | 0.1455 | 0.0909 | 0.2644 | 0.1136 | 0.0005 | 0.0038 | 0.0054 | 0.0222 | 0.0749 | 0.1073 | 0.1055 | 0.1318 | 0.5485 | 10 | 11 | 14 | 16 | 23 | 59 | 162 | 310 | 534 | 0.1363 | 42.26 | 4.688 | 0.5832 | 98205.2 | 84400000 | 91600000000 | 119000000000000 | 0.4503 | 0.1832 | 0.0986 | 0.0041 | 0.2120 | 0.0293 | 0.2896 | 0.1678 | 0.1638 | 0.1659 | 0.1033 | 0.2136 | 0.0800 | 0.1794 | 0.0287 | 0.0875 | 0.0194 | 0.0736 | 0.0047 | 0.0788 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0006 | 0.0008 | 0.0081 | 0.0047 | 0.0452 | 0.0417 | 0.0840 | 0.0727 | 0.0594 | 0.0422 | 0.0840 | 0.0743 | 0.7185 | 0.7635 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0024 | 0.0121 | 0.0159 | 0.0604 | 0.0675 | 0.1040 | 0.1154 | 0.0752 | 0.0819 | 0.1097 | 0.1185 | 0.6378 | 0.5984 | 0.0000 | 0.0001 | 0.0012 | 0.0086 | 0.0549 | 0.0904 | 0.0693 | 0.0991 | 0.6764 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 703 | 330 | 1517 | 7267 | 260.9 | 69.91 | 59.78 | 117.99 | 178 | 191 | 206 | 227 | 248 | 274 | 304 | 331 | 369 | 0.0860 | 625 | 1.115 | 107.79 | 38.05 | 1 | 0.1793 | 272 | 0.0105 | 1.72 | 4.763 | 0.5649 | 72953.0 | 21700000 | 6830000000 | 2240000000000 | 0.3508 | 0.2996 | 0.0016 | 0.0000 | 0.0031 | 0.0000 | 0.0062 | 0.0015 | 0.0171 | 0.0067 | 0.0715 | 0.0340 | 0.0964 | 0.0503 | 0.1026 | 0.0392 | 0.1291 | 0.0673 | 0.5723 | 0.8010 | 0.0010 | 0.0000 | 0.0019 | 0.0000 | 0.0019 | 0.0000 | 0.0057 | 0.0040 | 0.0306 | 0.0224 | 0.0373 | 0.0369 | 0.0335 | 0.0257 | 0.0450 | 0.0383 | 0.8431 | 0.8727 | 0.0025 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0061 | 0.0124 | 0.0549 | 0.0423 | 0.0610 | 0.0547 | 0.0549 | 0.0448 | 0.1220 | 0.0821 | 0.0854 | 0.7512 | 0.6159 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0337 | 0.0527 | 0.0366 | 0.0439 | 0.8228 | 7 | 8 | 9 | 10 | 11 | 15 | 28 | 57 | 188 | 0.1752 | 2.71 | 2.781 | 0.6871 | 17493.2 | 7830000 | 4090000000 | 2340000000000 | 0.4255 | 0.2007 | 0.0273 | 0.0043 | 0.0648 | 0.0086 | 0.1297 | 0.0114 | 0.2150 | 0.0643 | 0.2116 | 0.1186 | 0.1502 | 0.1686 | 0.1229 | 0.1429 | 0.0614 | 0.1629 | 0.0171 | 0.3186 | 0.0031 | 0.0010 | 0.0037 | 0.0021 | 0.0074 | 0.0026 | 0.0155 | 0.0129 | 0.0372 | 0.0290 | 0.0440 | 0.0403 | 0.0415 | 0.0445 | 0.0551 | 0.0672 | 0.7926 | 0.8004 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0023 | 0.0024 | 0.0053 | 0.0097 | 0.0371 | 0.0308 | 0.0393 | 0.0559 | 0.0446 | 0.0454 | 0.0598 | 0.0608 | 0.8086 | 0.7950 | 0.0000 | 0.0021 | 0.0049 | 0.0119 | 0.0295 | 0.0372 | 0.0400 | 0.0534 | 0.8209 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 666 | 790 | 3561 | 6069 | 315.0 | 63.10 | 119.80 | 156.57 | 227 | 261 | 284 | 299 | 314 | 331 | 348 | 367 | 395 | 0.1005 | 610 | 0.944 | 100.02 | 29.00 | 1 | 0.0702 | 250 | 0.0018 | 20.47 | 6.604 | 0.2773 | 103228.0 | 35100000 | 12300000000 | 4460000000000 | 0.4022 | 0.2404 | 0.0004 | 0.0003 | 0.0000 | 0.0003 | 0.0021 | 0.0003 | 0.0141 | 0.0006 | 0.0428 | 0.0204 | 0.0782 | 0.0351 | 0.0669 | 0.0260 | 0.0973 | 0.0348 | 0.6981 | 0.8823 | 0.0003 | 0.0003 | 0.0000 | 0.0003 | 0.0007 | 0.0003 | 0.0034 | 0.0003 | 0.0180 | 0.0162 | 0.0312 | 0.0272 | 0.0220 | 0.0139 | 0.0339 | 0.0210 | 0.8904 | 0.9206 | 0.0055 | 0.0000 | 0.0092 | 0.0000 | 0.0295 | 0.0000 | 0.0368 | 0.0000 | 0.0976 | 0.0000 | 0.1860 | 0.0000 | 0.0994 | 0.0000 | 0.1400 | 0.0000 | 0.3959 | 0.0000 | 0.0006 | 0.0011 | 0.0034 | 0.0169 | 0.0410 | 0.0713 | 0.0691 | 0.0871 | 0.7096 | 20 | 26 | 33 | 40 | 50 | 72 | 111 | 174 | 336 | 0.0366 | 13.58 | 4.709 | 0.5959 | 38861.2 | 20100000 | 13000000000 | 9720000000000 | 0.4035 | 0.2191 | 0.0130 | 0.0025 | 0.0681 | 0.0076 | 0.1426 | 0.0245 | 0.1313 | 0.0700 | 0.1361 | 0.1308 | 0.1669 | 0.1975 | 0.1070 | 0.1156 | 0.1216 | 0.1089 | 0.1135 | 0.3426 | 0.0000 | 0.0008 | 0.0005 | 0.0004 | 0.0044 | 0.0012 | 0.0112 | 0.0082 | 0.0486 | 0.0434 | 0.0816 | 0.0643 | 0.0505 | 0.0549 | 0.0802 | 0.0680 | 0.7230 | 0.7588 | 0.0007 | 0.0008 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0160 | 0.0159 | 0.0625 | 0.0700 | 0.1006 | 0.1026 | 0.0569 | 0.0644 | 0.0944 | 0.0907 | 0.6655 | 0.6547 | 0.0000 | 0.0035 | 0.0047 | 0.0135 | 0.0541 | 0.0858 | 0.0553 | 0.0829 | 0.7002 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1078 | 76 | 3929 | 6047 | 161.4 | 44.19 | 132.87 | 179.68 | 115 | 126 | 135 | 144 | 153 | 164 | 177 | 192 | 220 | 0.1057 | 639 | 1.011 | 168.43 | 62.07 | 1 | 0.1168 | 459 | 0.0015 | 39.33 | 6.819 | 0.1959 | 28002.9 | 5250000 | 1070000000 | 240000000000 | 0.4412 | 0.2076 | 0.0013 | 0.0000 | 0.0035 | 0.0003 | 0.0083 | 0.0017 | 0.0372 | 0.0034 | 0.0959 | 0.0278 | 0.1713 | 0.0613 | 0.1827 | 0.0573 | 0.1866 | 0.0994 | 0.3132 | 0.7487 | 0.0010 | 0.0000 | 0.0007 | 0.0003 | 0.0023 | 0.0003 | 0.0128 | 0.0000 | 0.0437 | 0.0177 | 0.0801 | 0.0303 | 0.0782 | 0.0230 | 0.1120 | 0.0483 | 0.6693 | 0.8803 | 0.0066 | 0.0058 | 0.0092 | 0.0203 | 0.0328 | 0.0407 | 0.0814 | 0.0872 | 0.1273 | 0.1802 | 0.1654 | 0.2122 | 0.1247 | 0.1105 | 0.1535 | 0.1337 | 0.2992 | 0.2093 | 0.0035 | 0.0035 | 0.0106 | 0.0388 | 0.1052 | 0.1240 | 0.1217 | 0.1499 | 0.4427 | 9 | 12 | 16 | 25 | 49 | 95 | 150 | 233 | 366 | 0.0201 | 68.11 | 5.908 | 0.3842 | 49932.6 | 27200000 | 17800000000 | 13000000000000 | 0.5438 | 0.1149 | 0.0657 | 0.0029 | 0.2044 | 0.0115 | 0.2117 | 0.1319 | 0.1387 | 0.1616 | 0.1515 | 0.2122 | 0.0985 | 0.1539 | 0.0511 | 0.1023 | 0.0547 | 0.0918 | 0.0237 | 0.1319 | 0.0004 | 0.0000 | 0.0018 | 0.0004 | 0.0009 | 0.0031 | 0.0234 | 0.0147 | 0.0661 | 0.0570 | 0.0974 | 0.0892 | 0.0793 | 0.0694 | 0.1058 | 0.0927 | 0.6249 | 0.6735 | 0.0017 | 0.0007 | 0.0006 | 0.0000 | 0.0076 | 0.0046 | 0.0285 | 0.0359 | 0.0802 | 0.0894 | 0.1197 | 0.1305 | 0.0953 | 0.0868 | 0.1104 | 0.1194 | 0.5561 | 0.5329 | 0.0010 | 0.0030 | 0.0081 | 0.0186 | 0.0756 | 0.1149 | 0.0832 | 0.1144 | 0.5811 | |||
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1120 | 374 | 1013 | 7639 | 932.9 | 280.82 | 18.77 | 68.99 | 520 | 632 | 745 | 866 | 972 | 1068 | 1154 | 1217 | 1274 | 0.0730 | 558 | 0.951 | 63.01 | 16.64 | 2 | 0.1382 | 140 | 0.0016 | 66.58 | 6.568 | 0.1620 | 949022.0 | 1030000000 | 1160000000000 | 1.34E+15 | 0.2997 | 0.3332 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0013 | 0.0141 | 0.0025 | 0.1155 | 0.0401 | 0.2197 | 0.0877 | 0.1380 | 0.0401 | 0.1662 | 0.0677 | 0.3437 | 0.7607 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0000 | 0.0368 | 0.0311 | 0.0637 | 0.0681 | 0.0326 | 0.0219 | 0.0425 | 0.0381 | 0.8201 | 0.8408 | 0.0000 | 0.0000 | 0.0000 | 0.0145 | 0.0000 | 0.0000 | 0.0171 | 0.0580 | 0.0484 | 0.1449 | 0.0883 | 0.1014 | 0.0570 | 0.1014 | 0.0712 | 0.2029 | 0.7179 | 0.3768 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0427 | 0.0816 | 0.0278 | 0.0594 | 0.7885 | 4 | 5 | 6 | 6 | 8 | 8 | 9 | 11 | 13 | 0.1323 | 2.99 | 1.460 | 0.4553 | 5111.7 | 3110000 | 2280000000 | 1870000000000 | 0.4103 | 0.1711 | 0.2687 | 0.1623 | 0.2463 | 0.1455 | 0.2015 | 0.1545 | 0.2612 | 0.1636 | 0.0224 | 0.1325 | 0.0000 | 0.1273 | 0.0000 | 0.0688 | 0.0000 | 0.0416 | 0.0000 | 0.0039 | 0.0357 | 0.1050 | 0.0187 | 0.0915 | 0.0221 | 0.0882 | 0.0306 | 0.0747 | 0.0629 | 0.0571 | 0.0510 | 0.0756 | 0.0952 | 0.0655 | 0.0799 | 0.0756 | 0.6037 | 0.3669 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0066 | 0.0000 | 0.0176 | 0.0143 | 0.0683 | 0.0903 | 0.1101 | 0.1021 | 0.0551 | 0.0570 | 0.0991 | 0.1069 | 0.6410 | 0.6295 | 0.0100 | 0.0060 | 0.0040 | 0.0260 | 0.0680 | 0.0820 | 0.0740 | 0.0900 | 0.6400 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1200 | 960 | 312 | 3292 | 82.5 | 11.29 | 23.21 | 72.43 | 68 | 73 | 76 | 79 | 82 | 86 | 89 | 93 | 97 | 0.1206 | 397 | 1.136 | 33.29 | 11.66 | 2 | 0.2724 | 85 | 0.0754 | 0.90 | 2.811 | 0.6827 | 6932.2 | 592793 | 51500000 | 4550000000 | 0.3990 | 0.2389 | 0.0037 | 0.0000 | 0.0000 | 0.0032 | 0.0112 | 0.0000 | 0.0485 | 0.0096 | 0.0672 | 0.0737 | 0.1194 | 0.0833 | 0.0933 | 0.0481 | 0.1604 | 0.0705 | 0.4963 | 0.7115 | 0.0034 | 0.0000 | 0.0000 | 0.0032 | 0.0069 | 0.0000 | 0.0206 | 0.0096 | 0.0481 | 0.0737 | 0.0997 | 0.0833 | 0.0378 | 0.0481 | 0.0722 | 0.0705 | 0.7113 | 0.7115 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.2609 | 0.0000 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0120 | 0.0180 | 0.0299 | 0.0539 | 0.0898 | 0.2275 | 0.0958 | 0.1078 | 0.3653 | 5 | 6 | 8 | 8 | 9 | 10 | 11 | 12 | 16 | 0.2788 | 2.99 | 1.539 | 0.6666 | 5783.0 | 2740000 | 1470000000 | 851000000000 | 0.3576 | 0.2571 | 0.1333 | 0.2774 | 0.2167 | 0.1473 | 0.3500 | 0.1130 | 0.1833 | 0.1541 | 0.0833 | 0.1336 | 0.0333 | 0.1199 | 0.0000 | 0.0411 | 0.0000 | 0.0103 | 0.0000 | 0.0034 | 0.0217 | 0.1656 | 0.0072 | 0.0879 | 0.0109 | 0.0573 | 0.0217 | 0.0613 | 0.0435 | 0.0327 | 0.0942 | 0.0675 | 0.0471 | 0.0409 | 0.0870 | 0.0695 | 0.6667 | 0.4172 | 0.0000 | 0.0000 | 0.0093 | 0.0000 | 0.0046 | 0.0000 | 0.0139 | 0.0203 | 0.0509 | 0.0711 | 0.1111 | 0.0863 | 0.0556 | 0.0761 | 0.0787 | 0.0863 | 0.6759 | 0.6599 | 0.0042 | 0.0042 | 0.0211 | 0.0253 | 0.0506 | 0.0717 | 0.0717 | 0.0928 | 0.6582 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 211 | 348 | 4562 | 14662 | 292.1 | 59.07 | 135.81 | 209.30 | 220 | 241 | 258 | 274 | 289 | 304 | 320 | 340 | 367 | 0.0645 | 945 | 0.932 | 136.85 | 50.12 | 1 | 0.0855 | 390 | 0.0007 | 74.36 | 7.435 | 0.1412 | 88808.4 | 28100000 | 9250000000 | 3170000000000 | 0.4402 | 0.2161 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0029 | 0.0000 | 0.0167 | 0.0014 | 0.0694 | 0.0171 | 0.1478 | 0.0364 | 0.1491 | 0.0316 | 0.1825 | 0.0583 | 0.4299 | 0.8552 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0018 | 0.0000 | 0.0071 | 0.0004 | 0.0325 | 0.0141 | 0.0723 | 0.0270 | 0.0621 | 0.0175 | 0.0948 | 0.0314 | 0.7283 | 0.9096 | 0.0085 | 0.0305 | 0.0142 | 0.0534 | 0.0355 | 0.0763 | 0.1050 | 0.1374 | 0.1475 | 0.1527 | 0.2014 | 0.1450 | 0.1078 | 0.1145 | 0.1362 | 0.1069 | 0.2440 | 0.1832 | 0.0009 | 0.0045 | 0.0095 | 0.0345 | 0.0971 | 0.1324 | 0.1261 | 0.1515 | 0.4435 | 11 | 12 | 14 | 17 | 22 | 47 | 116 | 250 | 458 | 0.0764 | 33.39 | 4.749 | 0.5335 | 62246.8 | 39200000 | 28700000000 | 23200000000000 | 0.5235 | 0.1167 | 0.0898 | 0.0014 | 0.2511 | 0.0304 | 0.2735 | 0.1824 | 0.1276 | 0.2041 | 0.1024 | 0.2020 | 0.0589 | 0.1399 | 0.0449 | 0.0878 | 0.0337 | 0.0662 | 0.0182 | 0.0858 | 0.0002 | 0.0002 | 0.0002 | 0.0002 | 0.0026 | 0.0024 | 0.0088 | 0.0086 | 0.0505 | 0.0448 | 0.0827 | 0.0772 | 0.0569 | 0.0558 | 0.0882 | 0.0792 | 0.7098 | 0.7318 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0021 | 0.0017 | 0.0094 | 0.0111 | 0.0555 | 0.0599 | 0.0916 | 0.1008 | 0.0699 | 0.0806 | 0.1010 | 0.1079 | 0.6706 | 0.6378 | 0.0002 | 0.0015 | 0.0015 | 0.0077 | 0.0503 | 0.0907 | 0.0609 | 0.0912 | 0.6961 | |
MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 461 | 123 | 3257 | 6809 | 514.7 | 105.53 | 61.25 | 124.20 | 368 | 433 | 474 | 500 | 525 | 551 | 579 | 608 | 638 | 0.0824 | 561 | 0.766 | 87.00 | 16.03 | 3 | 0.0620 | 202 | 0.0010 | 52.75 | 7.148 | 0.1825 | 276060.0 | 153000000 | 86800000000 | 50400000000000 | 0.4286 | 0.2196 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0068 | 0.0000 | 0.0140 | 0.0013 | 0.0512 | 0.0198 | 0.0978 | 0.0406 | 0.0965 | 0.0227 | 0.1277 | 0.0373 | 0.6046 | 0.8782 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0029 | 0.0013 | 0.0220 | 0.0197 | 0.0447 | 0.0384 | 0.0293 | 0.0184 | 0.0411 | 0.0288 | 0.8596 | 0.8934 | 0.0077 | 0.1333 | 0.0173 | 0.1333 | 0.0288 | 0.0667 | 0.0865 | 0.1333 | 0.1404 | 0.2667 | 0.1442 | 0.1333 | 0.1231 | 0.0000 | 0.1654 | 0.1333 | 0.2865 | 0.0000 | 0.0011 | 0.0023 | 0.0079 | 0.0186 | 0.0514 | 0.0814 | 0.0729 | 0.1040 | 0.6605 | 7 | 9 | 11 | 12 | 14 | 19 | 31 | 56 | 175 | 0.1883 | 7.43 | 3.201 | 0.7374 | 19174.6 | 10600000 | 7360000000 | 5780000000000 | 0.4921 | 0.1647 | 0.0338 | 0.0142 | 0.0549 | 0.0252 | 0.0717 | 0.0377 | 0.0928 | 0.0660 | 0.1392 | 0.0849 | 0.1814 | 0.1289 | 0.2363 | 0.1321 | 0.1097 | 0.1525 | 0.0802 | 0.3585 | 0.0034 | 0.0045 | 0.0048 | 0.0078 | 0.0034 | 0.0111 | 0.0109 | 0.0167 | 0.0212 | 0.0279 | 0.0519 | 0.0507 | 0.0355 | 0.0423 | 0.0444 | 0.0591 | 0.8245 | 0.7799 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0016 | 0.0000 | 0.0073 | 0.0078 | 0.0334 | 0.0336 | 0.0465 | 0.0509 | 0.0302 | 0.0259 | 0.0522 | 0.0578 | 0.8280 | 0.8240 | 0.0008 | 0.0008 | 0.0046 | 0.0106 | 0.0236 | 0.0540 | 0.0274 | 0.0547 | 0.8237 | |
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 758 | 289 | 9172 | 25842 | 480.5 | 106.34 | 78.95 | 164.92 | 348 | 401 | 442 | 475 | 501 | 523 | 545 | 566 | 596 | 0.0441 | 1140 | 0.391 | 100.72 | 18.03 | 8 | 0.0345 | 316 | 0.0008 | 40.91 | 7.452 | 0.2087 | 242144.0 | 126000000 | 66900000000 | 36300000000000 | 0.4467 | 0.2018 | 0.0013 | 0.0000 | 0.0021 | 0.0000 | 0.0040 | 0.0000 | 0.0106 | 0.0006 | 0.0423 | 0.0150 | 0.0713 | 0.0262 | 0.0664 | 0.0166 | 0.1037 | 0.0291 | 0.6983 | 0.9124 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0017 | 0.0006 | 0.0200 | 0.0146 | 0.0359 | 0.0255 | 0.0241 | 0.0145 | 0.0416 | 0.0249 | 0.8754 | 0.9198 | 0.0060 | 0.0000 | 0.0172 | 0.0000 | 0.0139 | 0.0000 | 0.0404 | 0.0000 | 0.0841 | 0.0000 | 0.0986 | 0.0000 | 0.1138 | 0.0000 | 0.1456 | 0.0000 | 0.4805 | 0.0000 | 0.0004 | 0.0006 | 0.0024 | 0.0101 | 0.0324 | 0.0533 | 0.0494 | 0.0684 | 0.7831 | 9 | 11 | 12 | 14 | 17 | 24 | 40 | 89 | 218 | 0.1598 | 4.29 | 2.873 | 0.6588 | 33429.4 | 26600000 | 27600000000 | 33200000000000 | 0.5581 | 0.1027 | 0.0519 | 0.0043 | 0.1247 | 0.0179 | 0.1628 | 0.0737 | 0.1498 | 0.1096 | 0.1498 | 0.1412 | 0.1264 | 0.1537 | 0.0840 | 0.1174 | 0.0693 | 0.1232 | 0.0814 | 0.2590 | 0.0005 | 0.0006 | 0.0015 | 0.0017 | 0.0029 | 0.0034 | 0.0099 | 0.0097 | 0.0423 | 0.0371 | 0.0707 | 0.0584 | 0.0431 | 0.0425 | 0.0693 | 0.0689 | 0.7598 | 0.7777 | 0.0004 | 0.0002 | 0.0008 | 0.0000 | 0.0014 | 0.0044 | 0.0124 | 0.0143 | 0.0545 | 0.0581 | 0.0798 | 0.0856 | 0.0569 | 0.0579 | 0.0862 | 0.0954 | 0.7076 | 0.6841 | 0.0005 | 0.0016 | 0.0031 | 0.0104 | 0.0474 | 0.0722 | 0.0478 | 0.0770 | 0.7400 |