High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1243 | 854 | | 722 | 7966 | 63.7 | 17.26 | 99.18 | 192.37 | 47 | 51 | 53 | 56 | 60 | 63 | 68 | 74 | 85 | 0.0734 | 585 | 0.421 | 183.11 | 37.80 | 0 | 0.8726 | 630 | 0.0093 | 10.56 | 5.018 | 0.3434 | 4360.7 | 324711 | 26600000 | 2420000000 | 0.4665 | 0.1732 | 0.0048 | 0.0000 | 0.0238 | 0.0000 | 0.0499 | 0.0060 | 0.0950 | 0.0255 | 0.1354 | 0.0510 | 0.1853 | 0.0990 | 0.1663 | 0.1049 | 0.1663 | 0.1094 | 0.1734 | 0.6042 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0128 | 0.0028 | 0.0475 | 0.0097 | 0.0786 | 0.0444 | 0.1408 | 0.0819 | 0.1261 | 0.0611 | 0.1481 | 0.0833 | 0.4388 | 0.7167 | 0.0000 | 0.0000 | 0.0317 | 0.0377 | 0.0159 | 0.0755 | 0.0952 | 0.0755 | 0.1825 | 0.3019 | 0.1825 | 0.1321 | 0.1508 | 0.0566 | 0.1508 | 0.2075 | 0.1905 | 0.1132 | 0.0036 | 0.0180 | 0.0288 | 0.0791 | 0.1259 | 0.1691 | 0.1295 | 0.1511 | 0.2950 | 10 | 12 | 14 | 15 | 17 | 19 | 31 | 113 | 371 | 0.1151 | 73.14 | 4.084 | 0.5429 | 46837.2 | 32700000 | 27500000000 | 26300000000000 | 0.6007 | 0.1115 | 0.2664 | 0.0211 | 0.4953 | 0.1607 | 0.2103 | 0.5011 | 0.0280 | 0.1882 | 0.0000 | 0.0782 | 0.0000 | 0.0338 | 0.0000 | 0.0127 | 0.0000 | 0.0042 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0022 | 0.0015 | 0.0056 | 0.0036 | 0.0185 | 0.0247 | 0.0888 | 0.0781 | 0.1355 | 0.1183 | 0.0748 | 0.0848 | 0.1231 | 0.1177 | 0.5509 | 0.5707 | 0.0006 | 0.0007 | 0.0013 | 0.0041 | 0.0083 | 0.0082 | 0.0230 | 0.0211 | 0.0856 | 0.0958 | 0.1540 | 0.1501 | 0.0818 | 0.0795 | 0.1176 | 0.1291 | 0.5278 | 0.5115 | 0.0012 | 0.0024 | 0.0054 | 0.0198 | 0.0929 | 0.1360 | 0.0827 | 0.1210 | 0.5386 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1200 | 960 | | 312 | 3292 | 82.5 | 11.29 | 23.21 | 72.43 | 68 | 73 | 76 | 79 | 82 | 86 | 89 | 93 | 97 | 0.1206 | 397 | 1.136 | 33.29 | 11.66 | 2 | 0.2724 | 85 | 0.0754 | 0.90 | 2.811 | 0.6827 | 6932.2 | 592793 | 51500000 | 4550000000 | 0.3990 | 0.2389 | 0.0037 | 0.0000 | 0.0000 | 0.0032 | 0.0112 | 0.0000 | 0.0485 | 0.0096 | 0.0672 | 0.0737 | 0.1194 | 0.0833 | 0.0933 | 0.0481 | 0.1604 | 0.0705 | 0.4963 | 0.7115 | 0.0034 | 0.0000 | 0.0000 | 0.0032 | 0.0069 | 0.0000 | 0.0206 | 0.0096 | 0.0481 | 0.0737 | 0.0997 | 0.0833 | 0.0378 | 0.0481 | 0.0722 | 0.0705 | 0.7113 | 0.7115 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.2609 | 0.0000 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0120 | 0.0180 | 0.0299 | 0.0539 | 0.0898 | 0.2275 | 0.0958 | 0.1078 | 0.3653 | 5 | 6 | 8 | 8 | 9 | 10 | 11 | 12 | 16 | 0.2788 | 2.99 | 1.539 | 0.6666 | 5783.0 | 2740000 | 1470000000 | 851000000000 | 0.3576 | 0.2571 | 0.1333 | 0.2774 | 0.2167 | 0.1473 | 0.3500 | 0.1130 | 0.1833 | 0.1541 | 0.0833 | 0.1336 | 0.0333 | 0.1199 | 0.0000 | 0.0411 | 0.0000 | 0.0103 | 0.0000 | 0.0034 | 0.0217 | 0.1656 | 0.0072 | 0.0879 | 0.0109 | 0.0573 | 0.0217 | 0.0613 | 0.0435 | 0.0327 | 0.0942 | 0.0675 | 0.0471 | 0.0409 | 0.0870 | 0.0695 | 0.6667 | 0.4172 | 0.0000 | 0.0000 | 0.0093 | 0.0000 | 0.0046 | 0.0000 | 0.0139 | 0.0203 | 0.0509 | 0.0711 | 0.1111 | 0.0863 | 0.0556 | 0.0761 | 0.0787 | 0.0863 | 0.6759 | 0.6599 | 0.0042 | 0.0042 | 0.0211 | 0.0253 | 0.0506 | 0.0717 | 0.0717 | 0.0928 | 0.6582 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1120 | 374 | | 1013 | 7639 | 932.9 | 280.82 | 18.77 | 68.99 | 520 | 632 | 745 | 866 | 972 | 1068 | 1154 | 1217 | 1274 | 0.0730 | 558 | 0.951 | 63.01 | 16.64 | 2 | 0.1382 | 140 | 0.0016 | 66.58 | 6.568 | 0.1620 | 949022.0 | 1030000000 | 1160000000000 | 1.34E+15 | 0.2997 | 0.3332 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0013 | 0.0141 | 0.0025 | 0.1155 | 0.0401 | 0.2197 | 0.0877 | 0.1380 | 0.0401 | 0.1662 | 0.0677 | 0.3437 | 0.7607 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0000 | 0.0368 | 0.0311 | 0.0637 | 0.0681 | 0.0326 | 0.0219 | 0.0425 | 0.0381 | 0.8201 | 0.8408 | 0.0000 | 0.0000 | 0.0000 | 0.0145 | 0.0000 | 0.0000 | 0.0171 | 0.0580 | 0.0484 | 0.1449 | 0.0883 | 0.1014 | 0.0570 | 0.1014 | 0.0712 | 0.2029 | 0.7179 | 0.3768 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0427 | 0.0816 | 0.0278 | 0.0594 | 0.7885 | 4 | 5 | 6 | 6 | 8 | 8 | 9 | 11 | 13 | 0.1323 | 2.99 | 1.460 | 0.4553 | 5111.7 | 3110000 | 2280000000 | 1870000000000 | 0.4103 | 0.1711 | 0.2687 | 0.1623 | 0.2463 | 0.1455 | 0.2015 | 0.1545 | 0.2612 | 0.1636 | 0.0224 | 0.1325 | 0.0000 | 0.1273 | 0.0000 | 0.0688 | 0.0000 | 0.0416 | 0.0000 | 0.0039 | 0.0357 | 0.1050 | 0.0187 | 0.0915 | 0.0221 | 0.0882 | 0.0306 | 0.0747 | 0.0629 | 0.0571 | 0.0510 | 0.0756 | 0.0952 | 0.0655 | 0.0799 | 0.0756 | 0.6037 | 0.3669 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0066 | 0.0000 | 0.0176 | 0.0143 | 0.0683 | 0.0903 | 0.1101 | 0.1021 | 0.0551 | 0.0570 | 0.0991 | 0.1069 | 0.6410 | 0.6295 | 0.0100 | 0.0060 | 0.0040 | 0.0260 | 0.0680 | 0.0820 | 0.0740 | 0.0900 | 0.6400 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 164 | 879 | | 4050 | 8872 | 419.4 | 110.73 | 86.10 | 234.18 | 295 | 334 | 362 | 385 | 409 | 439 | 474 | 515 | 570 | 0.0979 | 869 | 0.960 | 155.00 | 54.01 | 3 | 0.1049 | 425 | 0.0007 | 76.29 | 7.489 | 0.1602 | 188142.0 | 89200000 | 44400000000 | 23100000000000 | 0.4137 | 0.2255 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0052 | 0.0000 | 0.0231 | 0.0043 | 0.0718 | 0.0210 | 0.1144 | 0.0459 | 0.1271 | 0.0397 | 0.1462 | 0.0559 | 0.5100 | 0.8333 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0000 | 0.0071 | 0.0013 | 0.0298 | 0.0149 | 0.0481 | 0.0238 | 0.0528 | 0.0149 | 0.0708 | 0.0245 | 0.7886 | 0.9206 | 0.0011 | 0.0000 | 0.0043 | 0.0099 | 0.0130 | 0.0099 | 0.0444 | 0.0759 | 0.0704 | 0.1452 | 0.1083 | 0.1716 | 0.0986 | 0.1089 | 0.1073 | 0.1584 | 0.5525 | 0.3201 | 0.0016 | 0.0032 | 0.0111 | 0.0185 | 0.0506 | 0.0749 | 0.0611 | 0.0870 | 0.6921 | 11 | 12 | 14 | 15 | 16 | 17 | 20 | 35 | 226 | 0.4982 | 14.49 | 2.220 | 0.8059 | 62249.3 | 81200000 | 135000000000 | 258000000000000 | 0.6303 | 0.0763 | 0.2131 | 0.0132 | 0.4262 | 0.1376 | 0.2295 | 0.3995 | 0.0546 | 0.1508 | 0.0546 | 0.1164 | 0.0219 | 0.1085 | 0.0000 | 0.0423 | 0.0000 | 0.0265 | 0.0000 | 0.0053 | 0.0007 | 0.0006 | 0.0055 | 0.0019 | 0.0097 | 0.0070 | 0.0194 | 0.0171 | 0.0947 | 0.0912 | 0.1418 | 0.1476 | 0.0705 | 0.0646 | 0.0961 | 0.0956 | 0.5615 | 0.5744 | 0.0008 | 0.0008 | 0.0032 | 0.0042 | 0.0071 | 0.0100 | 0.0301 | 0.0308 | 0.1013 | 0.1032 | 0.1362 | 0.1424 | 0.0831 | 0.0849 | 0.1077 | 0.1091 | 0.5305 | 0.5146 | 0.0022 | 0.0037 | 0.0066 | 0.0176 | 0.1051 | 0.1412 | 0.0713 | 0.1037 | 0.5485 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1215 | 861 | | 3007 | 9908 | 716.7 | 136.15 | 119.32 | 267.01 | 537 | 590 | 633 | 674 | 713 | 750 | 795 | 845 | 901 | 0.0779 | 772 | 1.131 | 79.76 | 31.58 | 2 | 0.0725 | 218 | 0.0010 | 52.74 | 7.117 | 0.1610 | 532255.0 | 408000000 | 323000000000 | 262000000000000 | 0.4330 | 0.2090 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0007 | 0.0651 | 0.0200 | 0.1481 | 0.0312 | 0.1456 | 0.0346 | 0.1792 | 0.0481 | 0.4484 | 0.8654 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0007 | 0.0316 | 0.0198 | 0.0643 | 0.0271 | 0.0583 | 0.0218 | 0.0671 | 0.0305 | 0.7723 | 0.9001 | 0.0040 | 0.0588 | 0.0059 | 0.0588 | 0.0198 | 0.0882 | 0.0931 | 0.3529 | 0.1802 | 0.2941 | 0.1842 | 0.0588 | 0.0911 | 0.0294 | 0.1564 | 0.0588 | 0.2653 | 0.0000 | 0.0000 | 0.0007 | 0.0041 | 0.0244 | 0.0807 | 0.1404 | 0.1065 | 0.1303 | 0.5129 | 7 | 9 | 10 | 11 | 13 | 16 | 31 | 132 | 393 | 0.2663 | 40.82 | 3.458 | 0.6732 | 85524.5 | 93100000 | 121000000000 | 174000000000000 | 0.6043 | 0.0864 | 0.1806 | 0.0164 | 0.2843 | 0.1228 | 0.2274 | 0.2439 | 0.1237 | 0.1735 | 0.1304 | 0.1571 | 0.0201 | 0.1489 | 0.0201 | 0.0687 | 0.0134 | 0.0491 | 0.0000 | 0.0196 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0063 | 0.0059 | 0.0680 | 0.0675 | 0.1151 | 0.0990 | 0.0657 | 0.0671 | 0.1024 | 0.0998 | 0.6425 | 0.6607 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0115 | 0.0085 | 0.0781 | 0.0846 | 0.1289 | 0.1455 | 0.0849 | 0.0795 | 0.1226 | 0.1286 | 0.5734 | 0.5516 | 0.0000 | 0.0000 | 0.0010 | 0.0097 | 0.0711 | 0.1178 | 0.0808 | 0.1168 | 0.6027 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 434 | 702 | | 366 | 1008 | 101.8 | 15.33 | 117.32 | 181.93 | 80 | 86 | 92 | 98 | 103 | 108 | 111 | 115 | 124 | 0.2123 | 214 | 1.232 | 111.40 | 47.13 | 1 | 0.7978 | 292 | 0.0164 | 2.19 | 4.307 | 0.5322 | 10587.6 | 1130000 | 122000000 | 13400000000 | 0.3074 | 0.3364 | 0.0000 | 0.0000 | 0.0035 | 0.0000 | 0.0000 | 0.0000 | 0.0211 | 0.0055 | 0.0526 | 0.0437 | 0.1719 | 0.1202 | 0.0842 | 0.0328 | 0.0982 | 0.0437 | 0.5684 | 0.7541 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0123 | 0.0055 | 0.0401 | 0.0437 | 0.1204 | 0.1202 | 0.0432 | 0.0328 | 0.0401 | 0.0437 | 0.7438 | 0.7541 | 0.0000 | 0.0000 | 0.0256 | 0.0000 | 0.0256 | 0.0000 | 0.1026 | 0.0000 | 0.1026 | 0.0000 | 0.2051 | 0.0000 | 0.1026 | 0.0000 | 0.2308 | 0.0000 | 0.2051 | 0.0000 | 0.0000 | 0.0000 | 0.0158 | 0.0263 | 0.0526 | 0.1316 | 0.0842 | 0.0947 | 0.5947 | 11 | 13 | 15 | 21 | 33 | 58 | 109 | 190 | 334 | 0.1012 | 55.96 | 4.139 | 0.5623 | 46830.7 | 29000000 | 21700000000 | 18100000000000 | 0.4240 | 0.1879 | 0.1642 | 0.0070 | 0.2537 | 0.0986 | 0.1642 | 0.1690 | 0.1493 | 0.1408 | 0.1194 | 0.1408 | 0.0896 | 0.1620 | 0.0448 | 0.1056 | 0.0149 | 0.0986 | 0.0000 | 0.0775 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0061 | 0.0027 | 0.0457 | 0.0348 | 0.0793 | 0.0668 | 0.1250 | 0.1364 | 0.0854 | 0.0668 | 0.1494 | 0.1337 | 0.5091 | 0.5588 | 0.0000 | 0.0043 | 0.0038 | 0.0086 | 0.0268 | 0.0172 | 0.0345 | 0.0302 | 0.1188 | 0.1207 | 0.1341 | 0.1466 | 0.0996 | 0.1034 | 0.1533 | 0.1767 | 0.4291 | 0.3922 | 0.0000 | 0.0035 | 0.0177 | 0.0389 | 0.0989 | 0.1272 | 0.1095 | 0.1484 | 0.4558 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 739 | 828 | | 3336 | 10996 | 733.4 | 131.67 | 162.29 | 302.51 | 560 | 619 | 661 | 696 | 729 | 766 | 805 | 848 | 907 | 0.0851 | 936 | 1.020 | 70.01 | 22.36 | 1 | 0.0525 | 175 | 0.0011 | 45.93 | 7.024 | 0.1864 | 555153.0 | 433000000 | 346000000000 | 284000000000000 | 0.4491 | 0.1924 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0070 | 0.0003 | 0.0488 | 0.0168 | 0.1141 | 0.0324 | 0.0930 | 0.0251 | 0.1439 | 0.0321 | 0.5920 | 0.8934 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0003 | 0.0255 | 0.0157 | 0.0541 | 0.0275 | 0.0375 | 0.0151 | 0.0620 | 0.0236 | 0.8185 | 0.9178 | 0.0041 | 0.0000 | 0.0000 | 0.0541 | 0.0269 | 0.1081 | 0.0579 | 0.2432 | 0.1467 | 0.1892 | 0.2004 | 0.2973 | 0.1240 | 0.0270 | 0.1508 | 0.0541 | 0.2893 | 0.0270 | 0.0000 | 0.0025 | 0.0105 | 0.0215 | 0.0732 | 0.0942 | 0.0905 | 0.1046 | 0.6031 | 8 | 10 | 11 | 12 | 14 | 20 | 71 | 262 | 593 | 0.2612 | 53.14 | 3.819 | 0.6522 | 117840.0 | 116000000 | 132000000000 | 164000000000000 | 0.5865 | 0.0859 | 0.1144 | 0.0083 | 0.2779 | 0.0904 | 0.2861 | 0.2629 | 0.1417 | 0.1599 | 0.1063 | 0.1460 | 0.0436 | 0.1252 | 0.0272 | 0.0918 | 0.0027 | 0.0668 | 0.0000 | 0.0487 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0007 | 0.0007 | 0.0093 | 0.0101 | 0.0593 | 0.0520 | 0.1052 | 0.1002 | 0.0576 | 0.0598 | 0.1014 | 0.0881 | 0.6657 | 0.6888 | 0.0000 | 0.0008 | 0.0008 | 0.0013 | 0.0024 | 0.0051 | 0.0154 | 0.0166 | 0.0675 | 0.0696 | 0.1110 | 0.1099 | 0.0667 | 0.0743 | 0.1082 | 0.1002 | 0.6280 | 0.6222 | 0.0000 | 0.0007 | 0.0011 | 0.0136 | 0.0618 | 0.1045 | 0.0674 | 0.0986 | 0.6522 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 386 | 707 | | 13530 | 19255 | 474.1 | 126.99 | 20.39 | 53.21 | 304 | 394 | 439 | 470 | 494 | 519 | 545 | 573 | 609 | 0.0718 | 1383 | 0.981 | 73.41 | 26.31 | 10 | 0.0152 | 205 | 0.0008 | 44.28 | 7.548 | 0.2080 | 240855.0 | 127000000 | 69400000000 | 38700000000000 | 0.5339 | 0.1308 | 0.0006 | 0.0000 | 0.0010 | 0.0001 | 0.0043 | 0.0006 | 0.0142 | 0.0018 | 0.0585 | 0.0189 | 0.1017 | 0.0371 | 0.0863 | 0.0264 | 0.1091 | 0.0426 | 0.6244 | 0.8725 | 0.0001 | 0.0000 | 0.0002 | 0.0001 | 0.0001 | 0.0000 | 0.0015 | 0.0008 | 0.0170 | 0.0145 | 0.0361 | 0.0292 | 0.0214 | 0.0147 | 0.0347 | 0.0225 | 0.8889 | 0.9183 | 0.0031 | 0.0204 | 0.0058 | 0.0051 | 0.0170 | 0.0636 | 0.0458 | 0.1018 | 0.1021 | 0.1552 | 0.1378 | 0.1578 | 0.1116 | 0.1603 | 0.1412 | 0.1425 | 0.4357 | 0.1934 | 0.0001 | 0.0006 | 0.0021 | 0.0108 | 0.0390 | 0.0782 | 0.0620 | 0.0866 | 0.7204 | 6 | 7 | 8 | 9 | 10 | 11 | 13 | 16 | 31 | 0.4315 | 1.39 | 1.784 | 0.8626 | 3247.0 | 1790000 | 1370000000 | 1200000000000 | 0.6652 | 0.0672 | 0.0808 | 0.0848 | 0.0820 | 0.0869 | 0.1165 | 0.0731 | 0.1440 | 0.0714 | 0.1647 | 0.0831 | 0.1540 | 0.1070 | 0.1277 | 0.1051 | 0.0977 | 0.1288 | 0.0326 | 0.2598 | 0.0277 | 0.0558 | 0.0224 | 0.0571 | 0.0301 | 0.0465 | 0.0388 | 0.0399 | 0.0653 | 0.0505 | 0.0774 | 0.0737 | 0.0629 | 0.0667 | 0.0863 | 0.0911 | 0.5891 | 0.5187 | 0.0078 | 0.0032 | 0.0078 | 0.0050 | 0.0078 | 0.0140 | 0.0168 | 0.0235 | 0.0588 | 0.0587 | 0.0748 | 0.0898 | 0.0643 | 0.0700 | 0.1019 | 0.1020 | 0.6599 | 0.6339 | 0.0183 | 0.0157 | 0.0223 | 0.0265 | 0.0465 | 0.0750 | 0.0550 | 0.0917 | 0.6490 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 644 | 509 | | 752 | 2601 | 109.3 | 22.70 | 27.66 | 36.83 | 79 | 89 | 97 | 104 | 110 | 117 | 123 | 130 | 139 | 0.1303 | 339 | 0.980 | 171.76 | 54.15 | 1 | 0.6197 | 466 | 0.0023 | 47.96 | 6.181 | 0.1607 | 12466.6 | 1470000 | 179000000 | 22400000000 | 0.3827 | 0.2423 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0151 | 0.0000 | 0.0538 | 0.0042 | 0.1075 | 0.0379 | 0.1613 | 0.0618 | 0.1527 | 0.0520 | 0.2022 | 0.0758 | 0.3032 | 0.7683 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0114 | 0.0041 | 0.0507 | 0.0346 | 0.0654 | 0.0553 | 0.0670 | 0.0346 | 0.1029 | 0.0581 | 0.7010 | 0.8133 | 0.0204 | 0.0000 | 0.0272 | 0.0909 | 0.0612 | 0.3636 | 0.0952 | 0.2727 | 0.1837 | 0.0909 | 0.1361 | 0.1818 | 0.1633 | 0.0000 | 0.1769 | 0.0000 | 0.1361 | 0.0000 | 0.0000 | 0.0025 | 0.0101 | 0.0404 | 0.0783 | 0.1364 | 0.1364 | 0.1338 | 0.4621 | 13 | 14 | 15 | 16 | 17 | 18 | 21 | 29 | 50 | 0.5312 | 1.01 | 1.471 | 0.9002 | 2121.0 | 439440 | 138000000 | 49900000000 | 0.6286 | 0.0988 | 0.0545 | 0.0328 | 0.0955 | 0.0864 | 0.2136 | 0.1351 | 0.2136 | 0.1033 | 0.1727 | 0.1360 | 0.1091 | 0.1360 | 0.0909 | 0.1241 | 0.0364 | 0.1311 | 0.0136 | 0.1152 | 0.0104 | 0.0219 | 0.0104 | 0.0629 | 0.0207 | 0.0950 | 0.0370 | 0.0673 | 0.1111 | 0.0994 | 0.1156 | 0.0892 | 0.1319 | 0.1001 | 0.1452 | 0.1235 | 0.4178 | 0.3406 | 0.0000 | 0.0000 | 0.0022 | 0.0249 | 0.0198 | 0.0305 | 0.0440 | 0.0693 | 0.1604 | 0.1662 | 0.1758 | 0.1801 | 0.1297 | 0.1468 | 0.1714 | 0.1634 | 0.2967 | 0.2188 | 0.0036 | 0.0073 | 0.0146 | 0.0419 | 0.1421 | 0.1512 | 0.1275 | 0.1658 | 0.3461 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 862 | 60 | | 536 | 8372 | 94.9 | 38.62 | 150.81 | 294.15 | 38 | 55 | 70 | 85 | 97 | 109 | 121 | 135 | 146 | 0.0688 | 576 | 0.456 | 105.65 | 21.93 | 2 | 0.7705 | 413 | 0.0025 | 45.30 | 6.078 | 0.1747 | 10500.4 | 1270000 | 163000000 | 21700000000 | 0.3490 | 0.2577 | 0.0000 | 0.0032 | 0.0057 | 0.0000 | 0.0345 | 0.0000 | 0.1149 | 0.0097 | 0.1782 | 0.0968 | 0.1782 | 0.1452 | 0.1322 | 0.1161 | 0.1379 | 0.1613 | 0.2184 | 0.4677 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0137 | 0.0024 | 0.0521 | 0.0471 | 0.0493 | 0.0659 | 0.0548 | 0.0329 | 0.0740 | 0.0776 | 0.7562 | 0.7741 | 0.0000 | 0.0000 | 0.0052 | 0.0000 | 0.0052 | 0.0087 | 0.0209 | 0.0435 | 0.0995 | 0.1130 | 0.0785 | 0.1130 | 0.1099 | 0.1217 | 0.1152 | 0.1739 | 0.5654 | 0.4261 | 0.0000 | 0.0000 | 0.0035 | 0.0142 | 0.0745 | 0.0816 | 0.0780 | 0.0957 | 0.6525 | 15 | 18 | 20 | 22 | 25 | 32 | 64 | 197 | 482 | 0.1543 | 30.36 | 3.816 | 0.6306 | 109258.0 | 124000000 | 171000000000 | 266000000000000 | 0.6017 | 0.0867 | 0.1678 | 0.0032 | 0.3557 | 0.0852 | 0.2550 | 0.2981 | 0.1040 | 0.2618 | 0.0570 | 0.1467 | 0.0336 | 0.1073 | 0.0201 | 0.0442 | 0.0067 | 0.0331 | 0.0000 | 0.0205 | 0.0010 | 0.0004 | 0.0025 | 0.0018 | 0.0029 | 0.0031 | 0.0152 | 0.0161 | 0.0678 | 0.0629 | 0.1130 | 0.0915 | 0.0683 | 0.0683 | 0.1170 | 0.1071 | 0.6123 | 0.6488 | 0.0006 | 0.0006 | 0.0012 | 0.0006 | 0.0069 | 0.0056 | 0.0242 | 0.0311 | 0.0806 | 0.0840 | 0.1163 | 0.1319 | 0.0996 | 0.0989 | 0.1232 | 0.1319 | 0.5475 | 0.5152 | 0.0011 | 0.0021 | 0.0037 | 0.0144 | 0.0880 | 0.1077 | 0.0859 | 0.1189 | 0.5781 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 525 | 784 | | 306 | 3162 | 64.0 | 11.66 | 117.65 | 178.73 | 49 | 52 | 58 | 61 | 64 | 67 | 70 | 74 | 79 | 0.1395 | 441 | 1.153 | 68.73 | 23.77 | 1 | 0.5556 | 170 | 0.0077 | 10.17 | 5.047 | 0.3110 | 4226.0 | 287862 | 20200000 | 1450000000 | 0.4562 | 0.1761 | 0.0000 | 0.0000 | 0.0147 | 0.0033 | 0.0196 | 0.0000 | 0.0686 | 0.0133 | 0.1520 | 0.0365 | 0.1765 | 0.1794 | 0.1520 | 0.0332 | 0.1912 | 0.1296 | 0.2255 | 0.6047 | 0.0000 | 0.0000 | 0.0118 | 0.0033 | 0.0039 | 0.0000 | 0.0433 | 0.0131 | 0.0630 | 0.0359 | 0.1299 | 0.1634 | 0.0591 | 0.0327 | 0.1378 | 0.0882 | 0.5512 | 0.6634 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0800 | 0.0000 | 0.0600 | 0.8000 | 0.2200 | 0.2000 | 0.2000 | 0.0000 | 0.1400 | 0.0000 | 0.1400 | 0.0000 | 0.1200 | 0.0000 | 0.0062 | 0.0124 | 0.0248 | 0.0559 | 0.1242 | 0.0994 | 0.1242 | 0.1180 | 0.4348 | 11 | 12 | 13 | 15 | 18 | 44 | 106 | 220 | 400 | 0.1851 | 37.34 | 4.002 | 0.6018 | 45776.0 | 25200000 | 16900000000 | 13200000000000 | 0.6720 | 0.0567 | 0.1282 | 0.0081 | 0.1949 | 0.0782 | 0.2513 | 0.1240 | 0.1179 | 0.1563 | 0.1128 | 0.1725 | 0.0667 | 0.1590 | 0.0359 | 0.0755 | 0.0359 | 0.0916 | 0.0564 | 0.1348 | 0.0010 | 0.0000 | 0.0010 | 0.0009 | 0.0040 | 0.0027 | 0.0210 | 0.0153 | 0.0791 | 0.0694 | 0.1351 | 0.1127 | 0.1011 | 0.0902 | 0.1592 | 0.1461 | 0.4985 | 0.5627 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0012 | 0.0054 | 0.0348 | 0.0312 | 0.1057 | 0.1098 | 0.1480 | 0.1707 | 0.1294 | 0.1328 | 0.1654 | 0.1667 | 0.4142 | 0.3821 | 0.0011 | 0.0000 | 0.0033 | 0.0255 | 0.0909 | 0.1408 | 0.1098 | 0.1663 | 0.4623 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1179 | 272 | | 484 | 417 | 15.1 | 6.24 | 5.44 | 2.42 | 10 | 11 | 12 | 12 | 13 | 15 | 16 | 18 | 23 | 0.4964 | 207 | 0.834 | 37.74 | 12.04 | 0 | 0.2397 | 116 | 0.0096 | 14.01 | 4.972 | 0.3037 | 265.5 | 5621.95 | 142364 | 4170000 | 0.3690 | 0.2458 | 0.0041 | 0.0000 | 0.0207 | 0.0000 | 0.0664 | 0.0000 | 0.1660 | 0.0426 | 0.1618 | 0.0727 | 0.1826 | 0.1053 | 0.1826 | 0.1328 | 0.1369 | 0.1529 | 0.0788 | 0.4937 | 0.0000 | 0.0000 | 0.0146 | 0.0000 | 0.0292 | 0.0000 | 0.0437 | 0.0325 | 0.0787 | 0.0433 | 0.1108 | 0.0584 | 0.1224 | 0.0714 | 0.1866 | 0.0952 | 0.4140 | 0.6991 | 0.0392 | 0.0000 | 0.0392 | 0.0476 | 0.0686 | 0.0635 | 0.0490 | 0.0794 | 0.0784 | 0.1429 | 0.1961 | 0.1111 | 0.0980 | 0.1111 | 0.1275 | 0.1111 | 0.3039 | 0.3333 | 0.0051 | 0.0256 | 0.0718 | 0.0821 | 0.1026 | 0.1333 | 0.1385 | 0.1179 | 0.3231 | 3 | 3 | 4 | 5 | 5 | 7 | 7 | 7 | 9 | 0.0300 | 14.00 | 3.917 | 0.2952 | 35.4 | 257.772 | 2032.6 | 17052.4 | 0.3900 | 0.1941 | 0.1136 | 0.0290 | 0.2652 | 0.0773 | 0.2803 | 0.2174 | 0.1667 | 0.2560 | 0.0909 | 0.2029 | 0.0530 | 0.1353 | 0.0303 | 0.0628 | 0.0000 | 0.0145 | 0.0000 | 0.0048 | 0.0032 | 0.0000 | 0.0194 | 0.0079 | 0.0809 | 0.0159 | 0.1748 | 0.0714 | 0.2201 | 0.1720 | 0.2071 | 0.1746 | 0.1909 | 0.2302 | 0.0906 | 0.2169 | 0.0129 | 0.1111 | 0.0734 | 0.0760 | 0.1751 | 0.2047 | 0.3277 | 0.3392 | 0.2260 | 0.2222 | 0.1186 | 0.0877 | 0.0395 | 0.0292 | 0.0395 | 0.0409 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0433 | 0.1300 | 0.2202 | 0.2238 | 0.1805 | 0.1336 | 0.0542 | 0.0072 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 779 | 488 | | 1658 | 7515 | 661.2 | 127.45 | 21.12 | 72.35 | 472 | 534 | 588 | 636 | 672 | 708 | 749 | 791 | 831 | 0.0896 | 673 | 1.056 | 79.26 | 20.40 | 1 | 0.1128 | 187 | 0.0037 | 8.63 | 5.897 | 0.3770 | 453371.0 | 321000000 | 233000000000 | 172000000000000 | 0.3992 | 0.2328 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0029 | 0.0000 | 0.0098 | 0.0018 | 0.0479 | 0.0231 | 0.0685 | 0.0358 | 0.0607 | 0.0219 | 0.0881 | 0.0328 | 0.7202 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0018 | 0.0283 | 0.0231 | 0.0358 | 0.0358 | 0.0253 | 0.0219 | 0.0365 | 0.0328 | 0.8718 | 0.8846 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0000 | 0.0344 | 0.0000 | 0.0531 | 0.0000 | 0.0531 | 0.0000 | 0.0688 | 0.0000 | 0.1000 | 0.0000 | 0.6781 | 0.0000 | 0.0011 | 0.0011 | 0.0034 | 0.0135 | 0.0270 | 0.0529 | 0.0450 | 0.0541 | 0.8018 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 12 | 17 | 0.1063 | 2.38 | 1.499 | 0.4250 | 5680.0 | 3330000 | 2380000000 | 1890000000000 | 0.4909 | 0.1207 | 0.0780 | 0.0610 | 0.2110 | 0.0749 | 0.2844 | 0.0999 | 0.2661 | 0.1207 | 0.0826 | 0.1914 | 0.0505 | 0.1692 | 0.0092 | 0.0874 | 0.0138 | 0.0707 | 0.0046 | 0.1248 | 0.0181 | 0.0352 | 0.0233 | 0.0424 | 0.0194 | 0.0488 | 0.0440 | 0.0456 | 0.0660 | 0.0697 | 0.0699 | 0.0689 | 0.0621 | 0.0817 | 0.0776 | 0.0961 | 0.6197 | 0.5116 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0054 | 0.0000 | 0.0090 | 0.0189 | 0.0667 | 0.0682 | 0.1189 | 0.0928 | 0.0360 | 0.0625 | 0.0811 | 0.0795 | 0.6829 | 0.6761 | 0.0016 | 0.0064 | 0.0096 | 0.0305 | 0.0595 | 0.0691 | 0.0740 | 0.0804 | 0.6688 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 972 | 177 | | 395 | 12546 | 117.2 | 19.48 | 22.21 | 93.56 | 93 | 98 | 104 | 109 | 113 | 121 | 128 | 137 | 146 | 0.0524 | 657 | 1.105 | 42.05 | 12.04 | 0 | 0.2380 | 94 | 0.0471 | 0.93 | 3.300 | 0.6696 | 14103.0 | 1740000 | 221000000 | 28700000000 | 0.3949 | 0.2407 | 0.0000 | 0.0000 | 0.0102 | 0.0000 | 0.0136 | 0.0000 | 0.0374 | 0.0127 | 0.0646 | 0.0433 | 0.1224 | 0.0738 | 0.1327 | 0.0585 | 0.1565 | 0.0916 | 0.4626 | 0.7201 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0085 | 0.0000 | 0.0254 | 0.0127 | 0.0366 | 0.0430 | 0.0732 | 0.0734 | 0.0704 | 0.0532 | 0.0789 | 0.0658 | 0.7042 | 0.7519 | 0.0000 | 0.0000 | 0.0164 | 1.0000 | 0.0492 | 0.0000 | 0.0820 | 0.0000 | 0.0984 | 0.0000 | 0.1639 | 0.0000 | 0.1148 | 0.0000 | 0.1967 | 0.0000 | 0.2787 | 0.0000 | 0.0055 | 0.0055 | 0.0000 | 0.0497 | 0.0552 | 0.0718 | 0.0939 | 0.0939 | 0.6243 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 14 | 0.1205 | 3.55 | 1.534 | 0.4274 | 9246.7 | 8900000 | 10500000000 | 13500000000000 | 0.4645 | 0.1926 | 0.0604 | 0.1758 | 0.1758 | 0.0687 | 0.2582 | 0.0929 | 0.3462 | 0.1414 | 0.1099 | 0.1980 | 0.0385 | 0.1737 | 0.0110 | 0.0747 | 0.0000 | 0.0485 | 0.0000 | 0.0263 | 0.0000 | 0.0672 | 0.0020 | 0.0227 | 0.0099 | 0.0180 | 0.0159 | 0.0164 | 0.0556 | 0.0469 | 0.0724 | 0.0618 | 0.0764 | 0.0641 | 0.1022 | 0.0821 | 0.6657 | 0.6208 | 0.0024 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0026 | 0.0182 | 0.0140 | 0.0654 | 0.0727 | 0.0956 | 0.0969 | 0.0690 | 0.0625 | 0.0920 | 0.0982 | 0.6550 | 0.6531 | 0.0000 | 0.0022 | 0.0065 | 0.0196 | 0.0577 | 0.0882 | 0.0719 | 0.0882 | 0.6656 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 686 | 761 | | 4278 | 10329 | 575.0 | 101.74 | 209.00 | 348.06 | 451 | 485 | 515 | 540 | 564 | 591 | 619 | 660 | 717 | 0.0947 | 978 | 1.233 | 88.57 | 39.70 | 1 | 0.0570 | 244 | 0.0015 | 26.90 | 6.732 | 0.2213 | 340946.0 | 208000000 | 131000000000 | 85100000000000 | 0.4370 | 0.2089 | 0.0003 | 0.0002 | 0.0016 | 0.0000 | 0.0010 | 0.0000 | 0.0070 | 0.0005 | 0.0491 | 0.0165 | 0.1035 | 0.0326 | 0.1032 | 0.0271 | 0.1478 | 0.0398 | 0.5865 | 0.8833 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0005 | 0.0000 | 0.0035 | 0.0002 | 0.0289 | 0.0138 | 0.0516 | 0.0248 | 0.0503 | 0.0145 | 0.0751 | 0.0227 | 0.7893 | 0.9239 | 0.0017 | 0.0000 | 0.0017 | 0.0408 | 0.0166 | 0.0510 | 0.0582 | 0.1633 | 0.1481 | 0.2041 | 0.1681 | 0.2245 | 0.0899 | 0.0714 | 0.1514 | 0.1633 | 0.3644 | 0.0816 | 0.0010 | 0.0000 | 0.0051 | 0.0314 | 0.0663 | 0.1352 | 0.1023 | 0.1180 | 0.5408 | 9 | 10 | 12 | 14 | 19 | 49 | 188 | 394 | 707 | 0.1793 | 74.24 | 4.505 | 0.5801 | 164813.0 | 178000000 | 227000000000 | 323000000000000 | 0.5252 | 0.1228 | 0.1229 | 0.0022 | 0.3301 | 0.0673 | 0.2337 | 0.2076 | 0.1108 | 0.1987 | 0.0723 | 0.2065 | 0.0723 | 0.1358 | 0.0313 | 0.0550 | 0.0193 | 0.0673 | 0.0072 | 0.0595 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0013 | 0.0020 | 0.0041 | 0.0055 | 0.0525 | 0.0486 | 0.0965 | 0.0858 | 0.0600 | 0.0532 | 0.0839 | 0.0776 | 0.7008 | 0.7272 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0014 | 0.0012 | 0.0090 | 0.0196 | 0.0690 | 0.0667 | 0.1063 | 0.1181 | 0.0788 | 0.0895 | 0.1095 | 0.1071 | 0.6259 | 0.5958 | 0.0000 | 0.0003 | 0.0000 | 0.0104 | 0.0509 | 0.1031 | 0.0686 | 0.0961 | 0.6707 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1163 | 489 | | 321 | 5383 | 116.6 | 17.58 | 10.59 | 16.86 | 93 | 99 | 105 | 110 | 115 | 122 | 128 | 133 | 140 | 0.0832 | 448 | 1.174 | 34.48 | 13.89 | 3 | 0.2897 | 93 | 0.0412 | 1.34 | 3.375 | 0.6192 | 13896.5 | 1690000 | 210000000 | 26600000000 | 0.3932 | 0.2232 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0000 | 0.0388 | 0.0156 | 0.0930 | 0.0498 | 0.1395 | 0.1090 | 0.1395 | 0.0592 | 0.1938 | 0.0935 | 0.3837 | 0.6729 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0243 | 0.0156 | 0.0590 | 0.0498 | 0.1007 | 0.1090 | 0.0833 | 0.0592 | 0.1111 | 0.0935 | 0.6146 | 0.6729 | 0.0333 | 0.0000 | 0.0667 | 0.0000 | 0.0333 | 0.0000 | 0.1667 | 0.0000 | 0.2667 | 0.0000 | 0.2000 | 0.0000 | 0.1000 | 0.0000 | 0.1000 | 0.0000 | 0.0333 | 0.0000 | 0.0000 | 0.0000 | 0.0258 | 0.0516 | 0.0839 | 0.1290 | 0.0710 | 0.1032 | 0.5355 | 3 | 5 | 6 | 6 | 7 | 8 | 9 | 10 | 13 | 0.1037 | 0.50 | 1.327 | 0.4010 | 396.2 | 39837.1 | 5690000 | 976000000 | 0.5867 | 0.1158 | 0.1081 | 0.0234 | 0.1521 | 0.0646 | 0.1822 | 0.1055 | 0.1683 | 0.1248 | 0.1992 | 0.1564 | 0.1228 | 0.1745 | 0.0533 | 0.1681 | 0.0139 | 0.1293 | 0.0000 | 0.0533 | 0.0717 | 0.0199 | 0.1019 | 0.0545 | 0.1150 | 0.0857 | 0.0980 | 0.0980 | 0.1194 | 0.1193 | 0.1073 | 0.1330 | 0.0772 | 0.1375 | 0.0728 | 0.1248 | 0.2366 | 0.2273 | 0.0433 | 0.0158 | 0.0226 | 0.0204 | 0.0377 | 0.0226 | 0.0377 | 0.0385 | 0.0734 | 0.0973 | 0.1092 | 0.1154 | 0.0923 | 0.0905 | 0.1224 | 0.1222 | 0.4614 | 0.4774 | 0.1188 | 0.1103 | 0.0827 | 0.0562 | 0.0615 | 0.0679 | 0.0679 | 0.0933 | 0.3415 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 652 | 166 | | 1359 | 6119 | 428.9 | 60.31 | 32.37 | 70.62 | 351 | 373 | 390 | 405 | 426 | 446 | 465 | 483 | 508 | 0.0709 | 434 | 0.794 | 97.08 | 19.70 | 1 | 0.1670 | 227 | 0.0023 | 22.07 | 6.272 | 0.2405 | 187585.0 | 83600000 | 38000000000 | 17500000000000 | 0.4204 | 0.2216 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0000 | 0.0061 | 0.0000 | 0.0462 | 0.0221 | 0.0688 | 0.0324 | 0.0592 | 0.0191 | 0.0897 | 0.0316 | 0.7265 | 0.8948 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0000 | 0.0016 | 0.0000 | 0.0293 | 0.0221 | 0.0443 | 0.0324 | 0.0332 | 0.0191 | 0.0546 | 0.0316 | 0.8347 | 0.8948 | 0.0259 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0776 | 0.0000 | 0.1638 | 0.0000 | 0.1983 | 0.0000 | 0.1207 | 0.0000 | 0.1379 | 0.0000 | 0.2759 | 0.0000 | 0.0000 | 0.0046 | 0.0077 | 0.0107 | 0.0475 | 0.0644 | 0.0706 | 0.0982 | 0.6963 | 6 | 8 | 9 | 10 | 11 | 13 | 15 | 23 | 79 | 0.3514 | 3.58 | 2.313 | 0.8106 | 6034.5 | 2460000 | 1350000000 | 863000000000 | 0.6003 | 0.1052 | 0.0807 | 0.0227 | 0.0807 | 0.0644 | 0.1211 | 0.0814 | 0.2870 | 0.1458 | 0.1435 | 0.1496 | 0.1480 | 0.1458 | 0.0762 | 0.1326 | 0.0583 | 0.1307 | 0.0045 | 0.1269 | 0.0088 | 0.0079 | 0.0044 | 0.0186 | 0.0071 | 0.0193 | 0.0274 | 0.0336 | 0.0398 | 0.0480 | 0.0548 | 0.0523 | 0.0610 | 0.0651 | 0.0839 | 0.0938 | 0.7129 | 0.6614 | 0.0000 | 0.0000 | 0.0044 | 0.0023 | 0.0055 | 0.0046 | 0.0143 | 0.0161 | 0.0539 | 0.0506 | 0.0462 | 0.0598 | 0.0616 | 0.0529 | 0.0935 | 0.0978 | 0.7206 | 0.7158 | 0.0020 | 0.0050 | 0.0090 | 0.0160 | 0.0548 | 0.0439 | 0.0499 | 0.1017 | 0.7178 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 553 | 850 | | 1687 | 2459 | 300.5 | 204.06 | 15.65 | 29.61 | 110 | 143 | 172 | 196 | 226 | 271 | 333 | 444 | 654 | 0.1684 | 414 | 0.726 | 89.00 | 15.23 | 2 | 0.1114 | 188 | 0.0012 | 52.86 | 6.939 | 0.2192 | 131887.0 | 75200000 | 49500000000 | 35300000000000 | 0.3308 | 0.2934 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0059 | 0.0039 | 0.0676 | 0.0130 | 0.1618 | 0.0649 | 0.2176 | 0.1104 | 0.1294 | 0.0909 | 0.1147 | 0.1078 | 0.3029 | 0.6091 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0102 | 0.0089 | 0.0422 | 0.0337 | 0.0588 | 0.0452 | 0.0409 | 0.0425 | 0.0537 | 0.0558 | 0.7941 | 0.8113 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0045 | 0.0000 | 0.0045 | 0.0056 | 0.0543 | 0.0446 | 0.0860 | 0.0864 | 0.0294 | 0.0362 | 0.0633 | 0.0585 | 0.7579 | 0.7688 | 0.0000 | 0.0000 | 0.0000 | 0.0100 | 0.0434 | 0.0701 | 0.0484 | 0.0668 | 0.7613 | 6 | 7 | 8 | 9 | 10 | 11 | 11 | 13 | 16 | 0.6120 | 0.70 | 1.147 | 0.8761 | 1121.1 | 209476 | 49200000 | 12700000000 | 0.5069 | 0.1463 | 0.1731 | 0.0340 | 0.1621 | 0.0635 | 0.1264 | 0.1020 | 0.1978 | 0.1422 | 0.1264 | 0.1592 | 0.1209 | 0.1494 | 0.0604 | 0.1476 | 0.0275 | 0.1127 | 0.0055 | 0.0894 | 0.1136 | 0.0296 | 0.0971 | 0.0553 | 0.0531 | 0.0872 | 0.1081 | 0.1153 | 0.1117 | 0.1379 | 0.1026 | 0.1254 | 0.0861 | 0.1347 | 0.1081 | 0.1160 | 0.2198 | 0.1986 | 0.0110 | 0.0000 | 0.0385 | 0.0060 | 0.0055 | 0.0060 | 0.0220 | 0.0482 | 0.1154 | 0.1024 | 0.1264 | 0.1265 | 0.1154 | 0.1205 | 0.1209 | 0.1325 | 0.4451 | 0.4578 | 0.0618 | 0.0579 | 0.0734 | 0.0463 | 0.0888 | 0.1004 | 0.0811 | 0.1197 | 0.3707 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 646 | 621 | | 554 | 3317 | 275.3 | 19.34 | 19.44 | 28.31 | 251 | 261 | 267 | 272 | 276 | 281 | 286 | 292 | 299 | 0.1007 | 334 | 0.832 | 128.55 | 29.97 | 1 | 0.5108 | 283 | 0.0078 | 11.20 | 5.111 | 0.3312 | 76161.1 | 21200000 | 5910000000 | 1660000000000 | 0.3922 | 0.2458 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0453 | 0.0451 | 0.0652 | 0.0650 | 0.0380 | 0.0307 | 0.0580 | 0.0469 | 0.7935 | 0.8123 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0453 | 0.0451 | 0.0652 | 0.0650 | 0.0380 | 0.0307 | 0.0580 | 0.0469 | 0.7935 | 0.8123 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0100 | 0.0300 | 0.0533 | 0.0900 | 0.1667 | 0.1333 | 0.1567 | 0.3533 | 7 | 8 | 9 | 9 | 11 | 12 | 15 | 22 | 33 | 0.0979 | 0.55 | 1.508 | 0.4506 | 1178.9 | 161332 | 29100000 | 5860000000 | 0.5686 | 0.1153 | 0.0480 | 0.0687 | 0.1051 | 0.0634 | 0.1471 | 0.0569 | 0.1952 | 0.0838 | 0.2462 | 0.0967 | 0.1532 | 0.1267 | 0.0811 | 0.1590 | 0.0210 | 0.2105 | 0.0030 | 0.1343 | 0.0121 | 0.0433 | 0.0141 | 0.0377 | 0.0121 | 0.0314 | 0.0313 | 0.0328 | 0.0555 | 0.0370 | 0.0757 | 0.0656 | 0.0858 | 0.0628 | 0.1171 | 0.1172 | 0.5964 | 0.5722 | 0.0091 | 0.0139 | 0.0106 | 0.0239 | 0.0152 | 0.0359 | 0.0410 | 0.0478 | 0.0699 | 0.0896 | 0.1307 | 0.1116 | 0.1185 | 0.1116 | 0.1413 | 0.1434 | 0.4635 | 0.4223 | 0.0059 | 0.0059 | 0.0118 | 0.0403 | 0.0557 | 0.0853 | 0.0936 | 0.1256 | 0.5758 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1235 | 928 | | 3908 | 866 | 131.6 | 35.52 | 83.99 | 75.24 | 92 | 104 | 113 | 120 | 128 | 134 | 143 | 154 | 171 | 0.5855 | 507 | 1.261 | 98.62 | 31.32 | 1 | 0.0581 | 227 | 0.0023 | 24.71 | 6.369 | 0.2431 | 18576.3 | 2850000 | 480000000 | 90700000000 | 0.4962 | 0.1800 | 0.0025 | 0.0000 | 0.0025 | 0.0003 | 0.0091 | 0.0020 | 0.0313 | 0.0045 | 0.0844 | 0.0247 | 0.1671 | 0.0656 | 0.1560 | 0.0617 | 0.1844 | 0.1041 | 0.3627 | 0.7372 | 0.0000 | 0.0000 | 0.0013 | 0.0003 | 0.0026 | 0.0016 | 0.0107 | 0.0024 | 0.0488 | 0.0200 | 0.0837 | 0.0431 | 0.0755 | 0.0318 | 0.1153 | 0.0568 | 0.6620 | 0.8442 | 0.0109 | 0.0207 | 0.0125 | 0.0290 | 0.0498 | 0.0290 | 0.0888 | 0.1079 | 0.1495 | 0.1992 | 0.1947 | 0.1826 | 0.1137 | 0.0747 | 0.1340 | 0.1452 | 0.2461 | 0.2116 | 0.0012 | 0.0075 | 0.0184 | 0.0519 | 0.1308 | 0.1360 | 0.1314 | 0.1527 | 0.3700 | 16 | 24 | 36 | 50 | 62 | 79 | 105 | 130 | 176 | 0.0070 | 32.32 | 5.471 | 0.3545 | 12708.8 | 3020000 | 1050000000 | 473000000000 | 0.5943 | 0.0759 | 0.0880 | 0.0099 | 0.2240 | 0.0627 | 0.2160 | 0.0924 | 0.2480 | 0.1881 | 0.1600 | 0.2277 | 0.0560 | 0.2376 | 0.0080 | 0.0792 | 0.0000 | 0.0528 | 0.0000 | 0.0495 | 0.0150 | 0.0019 | 0.0200 | 0.0174 | 0.0324 | 0.0174 | 0.0549 | 0.0581 | 0.2893 | 0.2364 | 0.3566 | 0.3682 | 0.1322 | 0.1492 | 0.0574 | 0.0717 | 0.0424 | 0.0795 | 0.0072 | 0.0047 | 0.0217 | 0.0235 | 0.0580 | 0.0798 | 0.1051 | 0.1221 | 0.2754 | 0.2864 | 0.3370 | 0.3146 | 0.1123 | 0.0986 | 0.0507 | 0.0376 | 0.0326 | 0.0329 | 0.0151 | 0.0151 | 0.0272 | 0.1057 | 0.2779 | 0.3595 | 0.1178 | 0.0453 | 0.0363 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 680 | 724 | | 2796 | 6922 | 1289.3 | 297.81 | 11.57 | 14.75 | 882 | 996 | 1126 | 1218 | 1314 | 1409 | 1473 | 1547 | 1666 | 0.1000 | 692 | 0.449 | 77.06 | 17.03 | 1 | 0.0898 | 251 | 0.0006 | 162.50 | 7.490 | 0.1405 | 1750000.0 | 2480000000 | 3640000000000 | 5.5E+15 | 0.4200 | 0.2151 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0006 | 0.0000 | 0.0150 | 0.0008 | 0.0807 | 0.0218 | 0.1502 | 0.0514 | 0.1120 | 0.0327 | 0.1352 | 0.0510 | 0.5063 | 0.8419 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0004 | 0.0334 | 0.0184 | 0.0621 | 0.0376 | 0.0375 | 0.0192 | 0.0570 | 0.0289 | 0.8086 | 0.8955 | 0.0036 | 0.0000 | 0.0125 | 0.0215 | 0.0179 | 0.0538 | 0.0339 | 0.1075 | 0.1179 | 0.1720 | 0.1732 | 0.2151 | 0.0875 | 0.1183 | 0.1304 | 0.1720 | 0.4232 | 0.1398 | 0.0000 | 0.0000 | 0.0007 | 0.0061 | 0.0509 | 0.1141 | 0.0645 | 0.0971 | 0.6667 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 16 | 0.1442 | 0.50 | 1.438 | 0.5109 | 351.5 | 25544.2 | 2750000 | 377000000 | 0.5711 | 0.1027 | 0.1170 | 0.0291 | 0.1623 | 0.0624 | 0.1857 | 0.0979 | 0.1798 | 0.1155 | 0.1535 | 0.1440 | 0.0892 | 0.1715 | 0.0738 | 0.1552 | 0.0322 | 0.1366 | 0.0066 | 0.0877 | 0.0708 | 0.0240 | 0.0893 | 0.0506 | 0.0777 | 0.0776 | 0.0796 | 0.0886 | 0.0949 | 0.1002 | 0.0888 | 0.1140 | 0.1000 | 0.1166 | 0.1124 | 0.1369 | 0.2864 | 0.2915 | 0.0290 | 0.0090 | 0.0139 | 0.0030 | 0.0189 | 0.0060 | 0.0391 | 0.0571 | 0.1009 | 0.1141 | 0.1072 | 0.1096 | 0.0971 | 0.1096 | 0.1299 | 0.1276 | 0.4641 | 0.4640 | 0.0730 | 0.0589 | 0.0518 | 0.0754 | 0.0761 | 0.0934 | 0.1013 | 0.0879 | 0.3823 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 903 | 431 | | 54613 | 82874 | 84.8 | 46.65 | 114.00 | 205.41 | 23 | 28 | 54 | 73 | 87 | 99 | 112 | 126 | 146 | 0.0303 | 2514 | 0.607 | 231.82 | 52.47 | 24 | 0.0118 | 645 | 0.0046 | 13.65 | 6.351 | 0.3627 | 9367.0 | 1190000 | 165000000 | 24700000000 | 0.5125 | 0.1476 | 0.0017 | 0.0007 | 0.0076 | 0.0010 | 0.0380 | 0.0040 | 0.0801 | 0.0150 | 0.1435 | 0.0575 | 0.1828 | 0.1084 | 0.1675 | 0.1062 | 0.1626 | 0.1362 | 0.2163 | 0.5709 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0014 | 0.0002 | 0.0055 | 0.0015 | 0.0213 | 0.0119 | 0.0388 | 0.0234 | 0.0374 | 0.0198 | 0.0551 | 0.0316 | 0.8399 | 0.9117 | 0.0006 | 0.0018 | 0.0028 | 0.0048 | 0.0065 | 0.0130 | 0.0229 | 0.0391 | 0.0576 | 0.0808 | 0.0882 | 0.1189 | 0.0857 | 0.0985 | 0.1117 | 0.1228 | 0.6241 | 0.5203 | 0.0004 | 0.0014 | 0.0040 | 0.0124 | 0.0339 | 0.0605 | 0.0589 | 0.0824 | 0.7461 | 10 | 12 | 13 | 15 | 18 | 26 | 61 | 174 | 383 | 0.2390 | 19.16 | 3.787 | 0.6638 | 55186.4 | 40400000 | 36400000000 | 37700000000000 | 0.4605 | 0.1949 | 0.1576 | 0.0035 | 0.3814 | 0.0611 | 0.3071 | 0.3277 | 0.0839 | 0.2234 | 0.0408 | 0.1726 | 0.0158 | 0.1086 | 0.0071 | 0.0487 | 0.0039 | 0.0298 | 0.0026 | 0.0245 | 0.0001 | 0.0001 | 0.0006 | 0.0003 | 0.0013 | 0.0008 | 0.0117 | 0.0106 | 0.0652 | 0.0602 | 0.1027 | 0.0939 | 0.0640 | 0.0575 | 0.0983 | 0.0881 | 0.6561 | 0.6885 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0020 | 0.0025 | 0.0164 | 0.0184 | 0.0742 | 0.0778 | 0.1173 | 0.1225 | 0.0764 | 0.0817 | 0.1085 | 0.1098 | 0.6044 | 0.5860 | 0.0001 | 0.0002 | 0.0017 | 0.0132 | 0.0722 | 0.1105 | 0.0693 | 0.1056 | 0.6272 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 953 | 241 | | 4452 | 16651 | 514.3 | 202.79 | 16.75 | 22.48 | 264 | 314 | 365 | 425 | 496 | 574 | 650 | 721 | 776 | 0.0610 | 1016 | 0.831 | 150.81 | 30.46 | 9 | 0.0806 | 359 | 0.0007 | 46.67 | 7.524 | 0.1977 | 305620.0 | 203000000 | 146000000000 | 112000000000000 | 0.3891 | 0.2375 | 0.0008 | 0.0022 | 0.0000 | 0.0000 | 0.0142 | 0.0022 | 0.0334 | 0.0103 | 0.0943 | 0.0357 | 0.1060 | 0.0600 | 0.1018 | 0.0527 | 0.1277 | 0.0681 | 0.5217 | 0.7688 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0015 | 0.0003 | 0.0036 | 0.0052 | 0.0259 | 0.0196 | 0.0353 | 0.0304 | 0.0230 | 0.0232 | 0.0383 | 0.0312 | 0.8724 | 0.8898 | 0.0000 | 0.0000 | 0.0000 | 0.0044 | 0.0019 | 0.0044 | 0.0045 | 0.0166 | 0.0408 | 0.0376 | 0.0388 | 0.0564 | 0.0323 | 0.0431 | 0.0511 | 0.0818 | 0.8305 | 0.7558 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0262 | 0.0419 | 0.0295 | 0.0409 | 0.8548 | 6 | 7 | 8 | 9 | 11 | 14 | 17 | 22 | 30 | 0.1712 | 0.40 | 1.575 | 0.6158 | 785.9 | 143855 | 50100000 | 21000000000 | 0.6171 | 0.0868 | 0.0605 | 0.0488 | 0.0678 | 0.0590 | 0.0946 | 0.0585 | 0.1398 | 0.0738 | 0.1565 | 0.0814 | 0.1773 | 0.0904 | 0.1603 | 0.1323 | 0.1067 | 0.1903 | 0.0365 | 0.2655 | 0.0178 | 0.0287 | 0.0157 | 0.0319 | 0.0185 | 0.0277 | 0.0267 | 0.0319 | 0.0491 | 0.0406 | 0.0697 | 0.0463 | 0.0717 | 0.0582 | 0.1168 | 0.0921 | 0.6140 | 0.6425 | 0.0160 | 0.0168 | 0.0214 | 0.0291 | 0.0295 | 0.0412 | 0.0447 | 0.0496 | 0.0736 | 0.0814 | 0.0894 | 0.0941 | 0.1054 | 0.1129 | 0.1416 | 0.1313 | 0.4783 | 0.4436 | 0.0152 | 0.0164 | 0.0269 | 0.0290 | 0.0574 | 0.0696 | 0.0884 | 0.1384 | 0.5589 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1041 | 916 | | 403 | 1181 | 80.5 | 10.16 | 173.50 | 253.63 | 67 | 70 | 74 | 77 | 80 | 84 | 86 | 90 | 94 | 0.2320 | 274 | 1.030 | 30.08 | 8.00 | 0 | 0.1762 | 71 | 0.1226 | 0.50 | 2.391 | 0.7876 | 6578.3 | 546175 | 46000000 | 3940000000 | 0.3807 | 0.2394 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0188 | 0.0124 | 0.0591 | 0.0422 | 0.1237 | 0.1166 | 0.1022 | 0.0422 | 0.1532 | 0.0794 | 0.5376 | 0.7072 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0176 | 0.0124 | 0.0403 | 0.0422 | 0.1159 | 0.1166 | 0.0554 | 0.0422 | 0.0781 | 0.0794 | 0.6902 | 0.7072 | 0.0800 | 0.0000 | 0.0800 | 0.0000 | 0.0000 | 0.0000 | 0.2000 | 0.0000 | 0.1200 | 0.0000 | 0.0800 | 0.0000 | 0.2000 | 0.0000 | 0.2000 | 0.0000 | 0.0400 | 0.0000 | 0.0048 | 0.0000 | 0.0144 | 0.0383 | 0.1005 | 0.1340 | 0.0861 | 0.1627 | 0.4593 | 19 | 27 | 36 | 48 | 66 | 100 | 161 | 254 | 474 | 0.0380 | 54.53 | 4.632 | 0.4971 | 94375.3 | 84600000 | 95200000000 | 121000000000000 | 0.4414 | 0.1907 | 0.1038 | 0.0045 | 0.2264 | 0.0588 | 0.2170 | 0.1810 | 0.0472 | 0.1267 | 0.1415 | 0.2262 | 0.1321 | 0.1765 | 0.0943 | 0.0679 | 0.0189 | 0.0498 | 0.0189 | 0.1086 | 0.0000 | 0.0000 | 0.0026 | 0.0021 | 0.0026 | 0.0043 | 0.0490 | 0.0322 | 0.1108 | 0.1052 | 0.2010 | 0.1824 | 0.1031 | 0.0966 | 0.1237 | 0.1223 | 0.4072 | 0.4549 | 0.0035 | 0.0041 | 0.0142 | 0.0122 | 0.0284 | 0.0245 | 0.0674 | 0.0531 | 0.1418 | 0.1633 | 0.1596 | 0.1633 | 0.0887 | 0.0939 | 0.1348 | 0.1347 | 0.3617 | 0.3510 | 0.0030 | 0.0030 | 0.0119 | 0.0625 | 0.1310 | 0.1964 | 0.0923 | 0.1190 | 0.3810 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 533 | 682 | | 7313 | 29998 | 383.9 | 96.67 | 156.93 | 277.72 | 269 | 302 | 327 | 350 | 372 | 397 | 429 | 467 | 513 | 0.0399 | 1198 | 1.208 | 132.80 | 56.82 | 1 | 0.0483 | 353 | 0.0008 | 42.70 | 7.362 | 0.1796 | 156719.0 | 67700000 | 30900000000 | 14700000000000 | 0.4294 | 0.2186 | 0.0000 | 0.0002 | 0.0019 | 0.0000 | 0.0056 | 0.0006 | 0.0223 | 0.0032 | 0.0776 | 0.0240 | 0.1395 | 0.0531 | 0.1380 | 0.0451 | 0.1584 | 0.0649 | 0.4567 | 0.8089 | 0.0000 | 0.0001 | 0.0011 | 0.0000 | 0.0023 | 0.0003 | 0.0074 | 0.0016 | 0.0342 | 0.0155 | 0.0598 | 0.0314 | 0.0600 | 0.0208 | 0.0798 | 0.0327 | 0.7556 | 0.8977 | 0.0032 | 0.0056 | 0.0051 | 0.0093 | 0.0051 | 0.0075 | 0.0329 | 0.0746 | 0.0981 | 0.1362 | 0.1253 | 0.2034 | 0.1101 | 0.1063 | 0.1380 | 0.1716 | 0.4823 | 0.2854 | 0.0003 | 0.0015 | 0.0075 | 0.0301 | 0.0733 | 0.1004 | 0.0869 | 0.1025 | 0.5975 | 8 | 9 | 11 | 12 | 15 | 25 | 92 | 285 | 569 | 0.2355 | 33.94 | 3.958 | 0.6313 | 101753.0 | 91200000 | 98600000000 | 124000000000000 | 0.4779 | 0.1557 | 0.1073 | 0.0081 | 0.3320 | 0.0585 | 0.3330 | 0.2590 | 0.1394 | 0.2001 | 0.0471 | 0.2020 | 0.0301 | 0.1388 | 0.0090 | 0.0741 | 0.0020 | 0.0371 | 0.0000 | 0.0223 | 0.0002 | 0.0004 | 0.0006 | 0.0011 | 0.0008 | 0.0010 | 0.0076 | 0.0093 | 0.0425 | 0.0390 | 0.0726 | 0.0654 | 0.0486 | 0.0443 | 0.0803 | 0.0682 | 0.7467 | 0.7711 | 0.0001 | 0.0001 | 0.0004 | 0.0000 | 0.0019 | 0.0013 | 0.0107 | 0.0116 | 0.0477 | 0.0518 | 0.0894 | 0.1012 | 0.0658 | 0.0667 | 0.0972 | 0.1078 | 0.6868 | 0.6595 | 0.0000 | 0.0005 | 0.0009 | 0.0099 | 0.0457 | 0.0788 | 0.0566 | 0.0902 | 0.7173 |