LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 7 of 15: Mean cell count and mean growth rate across all replicates. - Dataset (ID:20243)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Mean Relative Cell Count Standard Error of the Mean for Relative Cell Count Mean Relative Growth Rate Standard Error of the Mean for Relative Growth Rate
MCF 10A Nintedanib
0.12
uM
LJP6
 0.9968 0.0075 0.9961 0.0087
MDA-MB-231 PD0325901
0.37
uM
LJP5
 0.4224 0.0075 0.2176 0.0156
MCF 10A PF431396
10.0
uM
LJP5
 0.0533 0.0075 -0.0509 0.0324
MCF7 Alpelisib
10.0
uM
LJP5
 0.2617 0.0075 -0.0255 0.0238
Hs 578T Erlotinib
0.37
uM
LJP5
 0.9662 0.0076 0.9548 0.0119
MCF 10A CGP60474
3.33
uM
LJP6
 0.0313 0.0076 -0.0759 0.0423
Hs 578T Afatinib
0.04
uM
LJP6
 0.9381 0.0076 0.9197 0.0063
SK-BR-3 Geldanamycin
0.37
uM
LJP6
 0.3562 0.0076 -0.0716 0.0508
Hs 578T Gefitinib
0.12
uM
LJP6
 0.9728 0.0077 0.9652 0.0085
MDA-MB-231 AZD8330
10.0
uM
LJP5
 0.3111 0.0077 0.0672 0.0037
Hs 578T GSK1904529A
10.0
uM
LJP6
 0.9451 0.0077 0.9278 0.0111
MCF 10A Alvocidib
1.11
uM
LJP6
 0.0309 0.0077 -0.0763 0.0415
MCF7 Torin1
3.33
uM
LJP6
 0.2682 0.0077 -0.0162 0.0184
BT-20 Dasatinib
10.0
uM
LJP6
 0.1966 0.0077 -0.1645 0.0275
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 0.1700 0.0077 -0.1240 0.0101
MCF 10A Buparlisib
10.0
uM
LJP5
 0.0474 0.0078 -0.0572 0.0291
BT-20 Sigma A6730
0.12
uM
LJP5
 0.8920 0.0078 0.8431 0.0144
Hs 578T Neratinib
0.04
uM
LJP5
 0.8927 0.0078 0.8602 0.0039
MCF7 Torin1
0.37
uM
LJP6
 0.3223 0.0078 0.0590 0.0144
MCF 10A GW843682X
3.33
uM
LJP6
 0.0718 0.0078 -0.0301 0.0276
BT-20 Brivanib
0.12
uM
LJP5
 0.9608 0.0078 0.9436 0.0103
SK-BR-3 CGP60474
0.37
uM
LJP6
 0.2567 0.0078 -0.2398 0.0808
Hs 578T Erlotinib
0.04
uM
LJP5
 0.9815 0.0079 0.9759 0.0103
Hs 578T Erlotinib
3.33
uM
LJP5
 0.9263 0.0079 0.9028 0.0129
SK-BR-3 Crizotinib
10.0
uM
LJP5
 0.3028 0.0079 -0.1607 0.0566