LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A BI-2536
3.33
uM
LJP6
 72
hr
 962 905 10605 0.0854 -0.0059
MCF 10A BMS345541
3.33
uM
LJP6
 72
hr
 962 10231 10605 0.9648 0.9612
MCF 10A SNS-032
3.33
uM
LJP6
 72
hr
 962 273 10605 0.0258 -0.0714
MCF 10A GDC-0980
3.33
uM
LJP5
 72
hr
 962 1254 10605 0.1183 0.0303
MCF 10A NVP-AEW541
3.33
uM
LJP5
 72
hr
 962 8808 10605 0.8306 0.8137
MCF 10A SB590885
3.33
uM
LJP5
 72
hr
 962 9798 10605 0.9240 0.9164
MCF 10A PIK-93
3.33
uM
LJP5
 72
hr
 962 8566 10605 0.8078 0.7886
MCF 10A KIN001-043
3.33
uM
LJP6
 72
hr
 962 8700 10605 0.8204 0.8024
MCF 10A Alpelisib
3.33
uM
LJP5
 72
hr
 962 8262 10605 0.7791 0.7571
MCF 10A Luminespib
3.33
uM
LJP5
 72
hr
 962 816 10605 0.0770 -0.0151
MCF 10A A443654
3.33
uM
LJP6
 72
hr
 962 316 10605 0.0298 -0.0670
MCF 10A OSI-027
3.33
uM
LJP6
 72
hr
 962 1575 10605 0.1485 0.0636
MCF 10A XMD11-85h
3.33
uM
LJP6
 72
hr
 962 10124 10605 0.9547 0.9502
MCF 10A HG-6-64-01
3.33
uM
LJP6
 72
hr
 962 6155 10605 0.5804 0.5386
MCF 10A WH-4-025
3.33
uM
LJP5
 72
hr
 962 2523 10605 0.2379 0.1619
MCF 10A WZ-4-145
3.33
uM
LJP6
 72
hr
 962 5531 10605 0.5216 0.4739
MCF 10A XMD16-144
3.33
uM
LJP5
 72
hr
 962 1265 10605 0.1193 0.0314
MCF 10A Brivanib
3.33
uM
LJP5
 72
hr
 962 7242 10605 0.6829 0.6512
MCF 10A Buparlisib
3.33
uM
LJP5
 72
hr
 962 1383 10605 0.1304 0.0436
MCF 10A BX-912
3.33
uM
LJP5
 72
hr
 962 1609 10605 0.1518 0.0671
MCF 10A Canertinib
3.33
uM
LJP6
 72
hr
 962 1509 10605 0.1423 0.0567
MCF 10A Celastrol
3.33
uM
LJP6
 72
hr
 962 374 10605 0.0353 -0.0609
MCF 10A CGP60474
3.33
uM
LJP5
 72
hr
 962 292 10605 0.0275 -0.0695
MCF 10A CGP60474
3.33
uM
LJP6
 72
hr
 962 238 10605 0.0224 -0.0751
MCF 10A CHIR-99021
3.33
uM
LJP6
 72
hr
 962 10194 10605 0.9612 0.9574