LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Nintedanib
0.04
uM
LJP6
 72
hr
 962 10963 10605 1.0338 1.0371
MCF 10A NU7441
0.04
uM
LJP5
 72
hr
 962 10789 10605 1.0173 1.0191
MCF 10A Dactolisib
0.04
uM
LJP5
 72
hr
 962 1625 10605 0.1532 0.0687
MCF 10A NVP-TAE684
0.04
uM
LJP6
 72
hr
 962 9483 10605 0.8942 0.8836
MCF 10A Palbociclib
0.04
uM
LJP6
 72
hr
 962 7377 10605 0.6956 0.6653
MCF 10A PD0325901
0.04
uM
LJP5
 72
hr
 962 2600 10605 0.2452 0.1699
MCF 10A PD0325901
0.04
uM
LJP6
 72
hr
 962 2212 10605 0.2086 0.1297
MCF 10A PD173074
0.04
uM
LJP6
 72
hr
 962 11072 10605 1.0441 1.0485
MCF 10A PD184352
0.04
uM
LJP5
 72
hr
 962 5377 10605 0.5071 0.4579
MCF 10A Pelitinib
0.04
uM
LJP5
 72
hr
 962 3164 10605 0.2984 0.2284
MCF 10A PF431396
0.04
uM
LJP5
 72
hr
 962 6508 10605 0.6137 0.5751
MCF 10A PF477736
0.04
uM
LJP5
 72
hr
 962 9697 10605 0.9144 0.9058
MCF 10A PF562271
0.04
uM
LJP6
 72
hr
 962 8699 10605 0.8203 0.8024
MCF 10A PHA-665752
0.04
uM
LJP5
 72
hr
 962 10474 10605 0.9877 0.9864
MCF 10A PHA-793887
0.04
uM
LJP6
 72
hr
 962 3090 10605 0.2914 0.2207
MCF 10A PI103
0.04
uM
LJP6
 72
hr
 962 9989 10605 0.9419 0.9361
MCF 10A PLX-4720
0.04
uM
LJP5
 72
hr
 962 10086 10605 0.9511 0.9462
MCF 10A QL-X-138
0.04
uM
LJP6
 72
hr
 962 11069 10605 1.0437 1.0481
MCF 10A QL-XII-47
0.04
uM
LJP6
 72
hr
 962 10065 10605 0.9491 0.9440
MCF 10A Radicicol
0.04
uM
LJP5
 72
hr
 962 9600 10605 0.9052 0.8958
MCF 10A Radicicol
0.04
uM
LJP6
 72
hr
 962 10049 10605 0.9476 0.9423
MCF 10A Seliciclib
0.04
uM
LJP5
 72
hr
 962 10269 10605 0.9683 0.9652
MCF 10A Ruxolitinib
0.04
uM
LJP5
 72
hr
 962 10310 10605 0.9722 0.9694
MCF 10A XL147
0.04
uM
LJP5
 72
hr
 962 10737 10605 1.0125 1.0137
MCF 10A Saracatinib
0.04
uM
LJP6
 72
hr
 962 10774 10605 1.0159 1.0175