LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Selumetinib
0.04
uM
LJP6
 72
hr
 962 4977 10605 0.4694 0.4164
MCF 10A Sirolimus
0.04
uM
LJP6
 72
hr
 962 9348 10605 0.8815 0.8697
MCF 10A Sorafenib
0.04
uM
LJP6
 72
hr
 962 10167 10605 0.9587 0.9546
MCF 10A SU11274
0.04
uM
LJP5
 72
hr
 962 10194 10605 0.9613 0.9574
MCF 10A Fedratinib
0.04
uM
LJP5
 72
hr
 962 9927 10605 0.9361 0.9297
MCF 10A TGX221
0.04
uM
LJP5
 72
hr
 962 10397 10605 0.9804 0.9785
MCF 10A Torin1
0.04
uM
LJP6
 72
hr
 962 5064 10605 0.4775 0.4254
MCF 10A Torin2
0.04
uM
LJP5
 72
hr
 962 1127 10605 0.1063 0.0172
MCF 10A Tozasertib
0.04
uM
LJP5
 72
hr
 962 2070 10605 0.1952 0.1149
MCF 10A Trametinib
0.04
uM
LJP5
 72
hr
 962 1790 10605 0.1688 0.0859
MCF 10A TWS119
0.04
uM
LJP5
 72
hr
 962 10550 10605 0.9948 0.9943
MCF 10A Vemurafenib
0.04
uM
LJP5
 72
hr
 962 10399 10605 0.9806 0.9786
MCF 10A Withaferin A
0.04
uM
LJP5
 72
hr
 962 10603 10605 0.9998 0.9998
MCF 10A Withaferin A
0.04
uM
LJP6
 72
hr
 962 10553 10605 0.9951 0.9946
MCF 10A WYE-125132
0.04
uM
LJP6
 72
hr
 962 3086 10605 0.2910 0.2203
MCF 10A WZ3105
0.04
uM
LJP5
 72
hr
 962 4977 10605 0.4694 0.4164
MCF 10A XMD11-50
0.04
uM
LJP6
 72
hr
 962 10001 10605 0.9431 0.9374
MCF 10A Y39983
0.04
uM
LJP6
 72
hr
 962 10258 10605 0.9673 0.9640
MCF 10A YM 201636
0.04
uM
LJP5
 72
hr
 962 10661 10605 1.0053 1.0059
MCF 10A ZSTK474
0.04
uM
LJP6
 72
hr
 962 10688 10605 1.0079 1.0087
MCF 10A Afatinib
0.12
uM
LJP6
 72
hr
 962 1521 10605 0.1435 0.0580
MCF 10A Sigma A6730
0.12
uM
LJP5
 72
hr
 962 10317 10605 0.9728 0.9701
MCF 10A Alvocidib
0.12
uM
LJP6
 72
hr
 962 320 10605 0.0302 -0.0666
MCF 10A AT-7519
0.12
uM
LJP6
 72
hr
 962 7625 10605 0.7191 0.6910
MCF 10A AZD 5438
0.12
uM
LJP6
 72
hr
 962 7001 10605 0.6602 0.6263