LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Radicicol
0.37
uM
LJP6
 72
hr
 962 2892 10605 0.2727 0.2002
MCF 10A Seliciclib
0.37
uM
LJP5
 72
hr
 962 9671 10605 0.9120 0.9032
MCF 10A Ruxolitinib
0.37
uM
LJP5
 72
hr
 962 10167 10605 0.9588 0.9546
MCF 10A XL147
0.37
uM
LJP5
 72
hr
 962 9449 10605 0.8911 0.8802
MCF 10A Saracatinib
0.37
uM
LJP6
 72
hr
 962 9678 10605 0.9126 0.9039
MCF 10A Selumetinib
0.37
uM
LJP6
 72
hr
 962 3234 10605 0.3050 0.2356
MCF 10A Sirolimus
0.37
uM
LJP6
 72
hr
 962 9293 10605 0.8763 0.8639
MCF 10A Sorafenib
0.37
uM
LJP6
 72
hr
 962 9369 10605 0.8835 0.8719
MCF 10A SU11274
0.37
uM
LJP5
 72
hr
 962 9108 10605 0.8589 0.8448
MCF 10A Fedratinib
0.37
uM
LJP5
 72
hr
 962 8912 10605 0.8404 0.8245
MCF 10A TGX221
0.37
uM
LJP5
 72
hr
 962 10319 10605 0.9731 0.9704
MCF 10A Torin1
0.37
uM
LJP6
 72
hr
 962 1730 10605 0.1631 0.0796
MCF 10A Torin2
0.37
uM
LJP5
 72
hr
 962 1347 10605 0.1270 0.0399
MCF 10A Tozasertib
0.37
uM
LJP5
 72
hr
 962 1384 10605 0.1305 0.0437
MCF 10A Trametinib
0.37
uM
LJP5
 72
hr
 962 1899 10605 0.1791 0.0972
MCF 10A TWS119
0.37
uM
LJP5
 72
hr
 962 10718 10605 1.0107 1.0117
MCF 10A Vemurafenib
0.37
uM
LJP5
 72
hr
 962 10309 10605 0.9721 0.9694
MCF 10A Withaferin A
0.37
uM
LJP5
 72
hr
 962 8349 10605 0.7873 0.7661
MCF 10A Withaferin A
0.37
uM
LJP6
 72
hr
 962 8178 10605 0.7711 0.7483
MCF 10A WYE-125132
0.37
uM
LJP6
 72
hr
 962 1620 10605 0.1528 0.0683
MCF 10A WZ3105
0.37
uM
LJP5
 72
hr
 962 522 10605 0.0493 -0.0456
MCF 10A XMD11-50
0.37
uM
LJP6
 72
hr
 962 7667 10605 0.7230 0.6953
MCF 10A Y39983
0.37
uM
LJP6
 72
hr
 962 9470 10605 0.8930 0.8823
MCF 10A YM 201636
0.37
uM
LJP5
 72
hr
 962 10078 10605 0.9503 0.9453
MCF 10A ZSTK474
0.37
uM
LJP6
 72
hr
 962 7328 10605 0.6910 0.6602