LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | BI-2536 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1253 | 4223 | 0.2969 | -0.0524 |
| SK-BR-3 | BMS345541 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 4153 | 4223 | 0.9835 | 0.9753 |
| SK-BR-3 | SNS-032 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1281 | 4223 | 0.3033 | -0.0427 |
| SK-BR-3 | GDC-0980 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1500 | 4223 | 0.3554 | 0.0351 |
| SK-BR-3 | NVP-AEW541 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4053 | 4223 | 0.9598 | 0.9398 |
| SK-BR-3 | SB590885 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4604 | 4223 | 1.0904 | 1.1352 |
| SK-BR-3 | PIK-93 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4374 | 4223 | 1.0357 | 1.0535 |
| SK-BR-3 | KIN001-043 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3926 | 4223 | 0.9297 | 0.8948 |
| SK-BR-3 | Alpelisib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3833 | 4223 | 0.9076 | 0.8618 |
| SK-BR-3 | Luminespib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1580 | 4223 | 0.3743 | 0.0635 |
| SK-BR-3 | A443654 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1287 | 4223 | 0.3049 | -0.0404 |
| SK-BR-3 | OSI-027 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1996 | 4223 | 0.4728 | 0.2109 |
| SK-BR-3 | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3561 | 4223 | 0.8432 | 0.7654 |
| SK-BR-3 | HG-6-64-01 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3544 | 4223 | 0.8392 | 0.7593 |
| SK-BR-3 | WH-4-025 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4448 | 4223 | 1.0533 | 1.0798 |
| SK-BR-3 | WZ-4-145 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 2521 | 4223 | 0.5970 | 0.3968 |
| SK-BR-3 | XMD16-144 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 1590 | 4223 | 0.3767 | 0.0670 |
| SK-BR-3 | Brivanib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4164 | 4223 | 0.9860 | 0.9791 |
| SK-BR-3 | Buparlisib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 2767 | 4223 | 0.6553 | 0.4841 |
| SK-BR-3 | BX-912 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3127 | 4223 | 0.7405 | 0.6115 |
| SK-BR-3 | Canertinib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1687 | 4223 | 0.3996 | 0.1014 |
| SK-BR-3 | Celastrol | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3535 | 4223 | 0.8371 | 0.7561 |
| SK-BR-3 | CGP60474 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 3015 | 4223 | 0.7139 | 0.5718 |
| SK-BR-3 | CGP60474 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1013 | 4223 | 0.2400 | -0.1375 |
| SK-BR-3 | CHIR-99021 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3900 | 4223 | 0.9236 | 0.8856 |