LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PD0325901 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4003 | 4223 | 0.9480 | 0.9221 |
| SK-BR-3 | PD0325901 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4163 | 4223 | 0.9859 | 0.9789 |
| SK-BR-3 | PD173074 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4426 | 4223 | 1.0481 | 1.0720 |
| SK-BR-3 | PD184352 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4357 | 4223 | 1.0319 | 1.0477 |
| SK-BR-3 | Pelitinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 2346 | 4223 | 0.5556 | 0.3349 |
| SK-BR-3 | PF431396 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4406 | 4223 | 1.0433 | 1.0648 |
| SK-BR-3 | PF477736 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1592 | 4223 | 0.3771 | 0.0676 |
| SK-BR-3 | PF562271 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4145 | 4223 | 0.9816 | 0.9724 |
| SK-BR-3 | PHA-665752 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4135 | 4223 | 0.9791 | 0.9688 |
| SK-BR-3 | PHA-793887 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 2158 | 4223 | 0.5112 | 0.2683 |
| SK-BR-3 | PI103 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3693 | 4223 | 0.8745 | 0.8121 |
| SK-BR-3 | PLX-4720 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4213 | 4223 | 0.9976 | 0.9964 |
| SK-BR-3 | QL-X-138 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3057 | 4223 | 0.7240 | 0.5870 |
| SK-BR-3 | QL-XII-47 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 2706 | 4223 | 0.6408 | 0.4623 |
| SK-BR-3 | Radicicol | 0.04 | uM | LJP5 | 72 | hr | 1401 | 2339 | 4223 | 0.5540 | 0.3325 |
| SK-BR-3 | Radicicol | 0.04 | uM | LJP6 | 72 | hr | 1401 | 2168 | 4223 | 0.5135 | 0.2719 |
| SK-BR-3 | Seliciclib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4169 | 4223 | 0.9873 | 0.9810 |
| SK-BR-3 | Ruxolitinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4243 | 4223 | 1.0047 | 1.0071 |
| SK-BR-3 | XL147 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4661 | 4223 | 1.1039 | 1.1554 |
| SK-BR-3 | Saracatinib | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4391 | 4223 | 1.0399 | 1.0597 |
| SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4622 | 4223 | 1.0945 | 1.1415 |
| SK-BR-3 | Sirolimus | 0.04 | uM | LJP6 | 72 | hr | 1401 | 2753 | 4223 | 0.6521 | 0.4792 |
| SK-BR-3 | Sorafenib | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3852 | 4223 | 0.9121 | 0.8685 |
| SK-BR-3 | SU11274 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4495 | 4223 | 1.0645 | 1.0966 |
| SK-BR-3 | Fedratinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4485 | 4223 | 1.0620 | 1.0928 |