LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MDA-MB-231 GW843682X
3.33
uM
LJP6
 72
hr
 1235 927 4513 0.2055 -0.0941
MDA-MB-231 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1235 1287 4513 0.2853 0.0158
MDA-MB-231 HG-5-88-01
3.33
uM
LJP6
 72
hr
 1235 4042 4513 0.8955 0.8561
MDA-MB-231 Imatinib
3.33
uM
LJP6
 72
hr
 1235 4334 4513 0.9604 0.9454
MDA-MB-231 JNK-9L
3.33
uM
LJP6
 72
hr
 1235 687 4513 0.1524 -0.1673
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 72
hr
 1235 2617 4513 0.5800 0.4216
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 72
hr
 1235 4234 4513 0.9382 0.9149
MDA-MB-231 LDN-193189
3.33
uM
LJP5
 72
hr
 1235 357 4513 0.0791 -0.2682
MDA-MB-231 Linifanib
3.33
uM
LJP6
 72
hr
 1235 4713 4513 1.0442 1.0608
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 72
hr
 1235 3795 4513 0.8409 0.7810
MDA-MB-231 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1235 185 4513 0.0411 -0.3204
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1235 205 4513 0.0455 -0.3144
MDA-MB-231 MK2206
3.33
uM
LJP6
 72
hr
 1235 3454 4513 0.7654 0.6769
MDA-MB-231 Neratinib
3.33
uM
LJP5
 72
hr
 1235 1539 4513 0.3411 0.0927
MDA-MB-231 Nilotinib
3.33
uM
LJP5
 72
hr
 1235 4171 4513 0.9242 0.8956
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 72
hr
 1235 4079 4513 0.9037 0.8674
MDA-MB-231 NU7441
3.33
uM
LJP5
 72
hr
 1235 2712 4513 0.6010 0.4505
MDA-MB-231 Dactolisib
3.33
uM
LJP5
 72
hr
 1235 1477 4513 0.3272 0.0735
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 72
hr
 1235 1283 4513 0.2843 0.0145
MDA-MB-231 Palbociclib
3.33
uM
LJP6
 72
hr
 1235 2077 4513 0.4602 0.2566
MDA-MB-231 PD0325901
3.33
uM
LJP5
 72
hr
 1235 1034 4513 0.2292 -0.0615
MDA-MB-231 PD0325901
3.33
uM
LJP6
 72
hr
 1235 735 4513 0.1630 -0.1526
MDA-MB-231 PD173074
3.33
uM
LJP6
 72
hr
 1235 4648 4513 1.0298 1.0410
MDA-MB-231 PD184352
3.33
uM
LJP5
 72
hr
 1235 2937 4513 0.6508 0.5191
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 72
hr
 1235 1581 4513 0.3503 0.1053