LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 PI103
0.12
uM
LJP6
72
hr
1097 2064 3769 0.5476 0.3619
BT-20 PLX-4720
0.12
uM
LJP5
72
hr
1097 3852 3769 1.0219 1.0309
BT-20 QL-X-138
0.12
uM
LJP6
72
hr
1097 2941 3769 0.7803 0.6901
BT-20 QL-XII-47
0.12
uM
LJP6
72
hr
1097 1649 3769 0.4375 0.2066
BT-20 Radicicol
0.12
uM
LJP5
72
hr
1097 2153 3769 0.5713 0.3953
BT-20 Radicicol
0.12
uM
LJP6
72
hr
1097 1746 3769 0.4632 0.2428
BT-20 Seliciclib
0.12
uM
LJP5
72
hr
1097 3839 3769 1.0186 1.0262
BT-20 Ruxolitinib
0.12
uM
LJP5
72
hr
1097 3629 3769 0.9628 0.9475
BT-20 XL147
0.12
uM
LJP5
72
hr
1097 4280 3769 1.1356 1.1913
BT-20 Saracatinib
0.12
uM
LJP6
72
hr
1097 3436 3769 0.9117 0.8754
BT-20 Selumetinib
0.12
uM
LJP6
72
hr
1097 3420 3769 0.9075 0.8695
BT-20 Sirolimus
0.12
uM
LJP6
72
hr
1097 2217 3769 0.5883 0.4193
BT-20 Sorafenib
0.12
uM
LJP6
72
hr
1097 3487 3769 0.9251 0.8943
BT-20 SU11274
0.12
uM
LJP5
72
hr
1097 3970 3769 1.0532 1.0750
BT-20 Fedratinib
0.12
uM
LJP5
72
hr
1097 3770 3769 1.0002 1.0003
BT-20 TGX221
0.12
uM
LJP5
72
hr
1097 3695 3769 0.9802 0.9721
BT-20 Torin1
0.12
uM
LJP6
72
hr
1097 1134 3769 0.3008 0.0138
BT-20 Torin2
0.12
uM
LJP5
72
hr
1097 926 3769 0.2458 -0.0638
BT-20 Tozasertib
0.12
uM
LJP5
72
hr
1097 1389 3769 0.3687 0.1094
BT-20 Trametinib
0.12
uM
LJP5
72
hr
1097 3041 3769 0.8067 0.7274
BT-20 TWS119
0.12
uM
LJP5
72
hr
1097 3757 3769 0.9967 0.9953
BT-20 Vemurafenib
0.12
uM
LJP5
72
hr
1097 3676 3769 0.9753 0.9651
BT-20 Withaferin A
0.12
uM
LJP5
72
hr
1097 4236 3769 1.1238 1.1747
BT-20 Withaferin A
0.12
uM
LJP6
72
hr
1097 3547 3769 0.9410 0.9167
BT-20 WYE-125132
0.12
uM
LJP6
72
hr
1097 1399 3769 0.3711 0.1129