LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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BT-20 | PI103 | 0.12 | uM | LJP6 | 72 | hr | 1097 | 2064 | 3769 | 0.5476 | 0.3619 |
BT-20 | PLX-4720 | 0.12 | uM | LJP5 | 72 | hr | 1097 | 3852 | 3769 | 1.0219 | 1.0309 |
BT-20 | QL-X-138 | 0.12 | uM | LJP6 | 72 | hr | 1097 | 2941 | 3769 | 0.7803 | 0.6901 |
BT-20 | QL-XII-47 | 0.12 | uM | LJP6 | 72 | hr | 1097 | 1649 | 3769 | 0.4375 | 0.2066 |
BT-20 | Radicicol | 0.12 | uM | LJP5 | 72 | hr | 1097 | 2153 | 3769 | 0.5713 | 0.3953 |
BT-20 | Radicicol | 0.12 | uM | LJP6 | 72 | hr | 1097 | 1746 | 3769 | 0.4632 | 0.2428 |
BT-20 | Seliciclib | 0.12 | uM | LJP5 | 72 | hr | 1097 | 3839 | 3769 | 1.0186 | 1.0262 |
BT-20 | Ruxolitinib | 0.12 | uM | LJP5 | 72 | hr | 1097 | 3629 | 3769 | 0.9628 | 0.9475 |
BT-20 | XL147 | 0.12 | uM | LJP5 | 72 | hr | 1097 | 4280 | 3769 | 1.1356 | 1.1913 |
BT-20 | Saracatinib | 0.12 | uM | LJP6 | 72 | hr | 1097 | 3436 | 3769 | 0.9117 | 0.8754 |
BT-20 | Selumetinib | 0.12 | uM | LJP6 | 72 | hr | 1097 | 3420 | 3769 | 0.9075 | 0.8695 |
BT-20 | Sirolimus | 0.12 | uM | LJP6 | 72 | hr | 1097 | 2217 | 3769 | 0.5883 | 0.4193 |
BT-20 | Sorafenib | 0.12 | uM | LJP6 | 72 | hr | 1097 | 3487 | 3769 | 0.9251 | 0.8943 |
BT-20 | SU11274 | 0.12 | uM | LJP5 | 72 | hr | 1097 | 3970 | 3769 | 1.0532 | 1.0750 |
BT-20 | Fedratinib | 0.12 | uM | LJP5 | 72 | hr | 1097 | 3770 | 3769 | 1.0002 | 1.0003 |
BT-20 | TGX221 | 0.12 | uM | LJP5 | 72 | hr | 1097 | 3695 | 3769 | 0.9802 | 0.9721 |
BT-20 | Torin1 | 0.12 | uM | LJP6 | 72 | hr | 1097 | 1134 | 3769 | 0.3008 | 0.0138 |
BT-20 | Torin2 | 0.12 | uM | LJP5 | 72 | hr | 1097 | 926 | 3769 | 0.2458 | -0.0638 |
BT-20 | Tozasertib | 0.12 | uM | LJP5 | 72 | hr | 1097 | 1389 | 3769 | 0.3687 | 0.1094 |
BT-20 | Trametinib | 0.12 | uM | LJP5 | 72 | hr | 1097 | 3041 | 3769 | 0.8067 | 0.7274 |
BT-20 | TWS119 | 0.12 | uM | LJP5 | 72 | hr | 1097 | 3757 | 3769 | 0.9967 | 0.9953 |
BT-20 | Vemurafenib | 0.12 | uM | LJP5 | 72 | hr | 1097 | 3676 | 3769 | 0.9753 | 0.9651 |
BT-20 | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 1097 | 4236 | 3769 | 1.1238 | 1.1747 |
BT-20 | Withaferin A | 0.12 | uM | LJP6 | 72 | hr | 1097 | 3547 | 3769 | 0.9410 | 0.9167 |
BT-20 | WYE-125132 | 0.12 | uM | LJP6 | 72 | hr | 1097 | 1399 | 3769 | 0.3711 | 0.1129 |