LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
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BT-20 | WZ3105 | 0.12 | uM | LJP5 | 72 | hr | 1097 | 1293 | 3769 | 0.3430 | 0.0733 |
BT-20 | XMD11-50 | 0.12 | uM | LJP6 | 72 | hr | 1097 | 2696 | 3769 | 0.7152 | 0.5983 |
BT-20 | Y39983 | 0.12 | uM | LJP6 | 72 | hr | 1097 | 3444 | 3769 | 0.9138 | 0.8784 |
BT-20 | YM 201636 | 0.12 | uM | LJP5 | 72 | hr | 1097 | 3822 | 3769 | 1.0141 | 1.0199 |
BT-20 | ZSTK474 | 0.12 | uM | LJP6 | 72 | hr | 1097 | 2700 | 3769 | 0.7163 | 0.5998 |
BT-20 | Afatinib | 0.37 | uM | LJP6 | 72 | hr | 1097 | 3081 | 3769 | 0.8173 | 0.7423 |
BT-20 | Sigma A6730 | 0.37 | uM | LJP5 | 72 | hr | 1097 | 3512 | 3769 | 0.9317 | 0.9036 |
BT-20 | Alvocidib | 0.37 | uM | LJP6 | 72 | hr | 1097 | 611 | 3769 | 0.1621 | -0.1820 |
BT-20 | AT-7519 | 0.37 | uM | LJP6 | 72 | hr | 1097 | 832 | 3769 | 0.2207 | -0.0993 |
BT-20 | AZD 5438 | 0.37 | uM | LJP6 | 72 | hr | 1097 | 1456 | 3769 | 0.3863 | 0.1343 |
BT-20 | AZD-6482 | 0.37 | uM | LJP5 | 72 | hr | 1097 | 2931 | 3769 | 0.7777 | 0.6865 |
BT-20 | AZD7762 | 0.37 | uM | LJP6 | 72 | hr | 1097 | 2115 | 3769 | 0.5611 | 0.3809 |
BT-20 | AZD8055 | 0.37 | uM | LJP6 | 72 | hr | 1097 | 1116 | 3769 | 0.2962 | 0.0071 |
BT-20 | AZD8330 | 0.37 | uM | LJP5 | 72 | hr | 1097 | 2988 | 3769 | 0.7928 | 0.7077 |
BT-20 | Barasertib | 0.37 | uM | LJP5 | 72 | hr | 1097 | 2041 | 3769 | 0.5415 | 0.3533 |
BT-20 | BI-2536 | 0.37 | uM | LJP6 | 72 | hr | 1097 | 800 | 3769 | 0.2123 | -0.1111 |
BT-20 | BMS345541 | 0.37 | uM | LJP6 | 72 | hr | 1097 | 3237 | 3769 | 0.8588 | 0.8008 |
BT-20 | SNS-032 | 0.37 | uM | LJP6 | 72 | hr | 1097 | 691 | 3769 | 0.1833 | -0.1520 |
BT-20 | GDC-0980 | 0.37 | uM | LJP5 | 72 | hr | 1097 | 868 | 3769 | 0.2304 | -0.0855 |
BT-20 | NVP-AEW541 | 0.37 | uM | LJP5 | 72 | hr | 1097 | 3860 | 3769 | 1.0240 | 1.0339 |
BT-20 | SB590885 | 0.37 | uM | LJP5 | 72 | hr | 1097 | 3951 | 3769 | 1.0482 | 1.0680 |
BT-20 | PIK-93 | 0.37 | uM | LJP5 | 72 | hr | 1097 | 3878 | 3769 | 1.0288 | 1.0406 |
BT-20 | KIN001-043 | 0.37 | uM | LJP6 | 72 | hr | 1097 | 3628 | 3769 | 0.9626 | 0.9473 |
BT-20 | Alpelisib | 0.37 | uM | LJP5 | 72 | hr | 1097 | 2957 | 3769 | 0.7845 | 0.6961 |
BT-20 | Luminespib | 0.37 | uM | LJP5 | 72 | hr | 1097 | 1128 | 3769 | 0.2994 | 0.0118 |