LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 JW-7-24-1
0.12
uM
LJP6
 72
hr
 1334 3536 3970 0.8906 0.8352
BT-20 Lapatinib
0.12
uM
LJP6
 72
hr
 1334 3995 3970 1.0061 1.0091
BT-20 LDN-193189
0.12
uM
LJP5
 72
hr
 1334 3838 3970 0.9665 0.9496
BT-20 Linifanib
0.12
uM
LJP6
 72
hr
 1334 4249 3970 1.0701 1.1056
BT-20 Linsitinib
0.12
uM
LJP5
 72
hr
 1334 3722 3970 0.9373 0.9056
BT-20 Mitoxantrone
0.12
uM
LJP5
 72
hr
 1334 1148 3970 0.2893 -0.0706
BT-20 Mitoxantrone
0.12
uM
LJP6
 72
hr
 1334 1526 3970 0.3845 0.0728
BT-20 MK2206
0.12
uM
LJP6
 72
hr
 1334 3952 3970 0.9954 0.9931
BT-20 Neratinib
0.12
uM
LJP5
 72
hr
 1334 2945 3970 0.7418 0.6111
BT-20 Nilotinib
0.12
uM
LJP5
 72
hr
 1334 4116 3970 1.0365 1.0550
BT-20 Nintedanib
0.12
uM
LJP6
 72
hr
 1334 4041 3970 1.0177 1.0267
BT-20 NU7441
0.12
uM
LJP5
 72
hr
 1334 4100 3970 1.0325 1.0490
BT-20 Dactolisib
0.12
uM
LJP5
 72
hr
 1334 1715 3970 0.4320 0.1444
BT-20 NVP-TAE684
0.12
uM
LJP6
 72
hr
 1334 3094 3970 0.7792 0.6674
BT-20 Palbociclib
0.12
uM
LJP6
 72
hr
 1334 2967 3970 0.7474 0.6194
BT-20 PD0325901
0.12
uM
LJP5
 72
hr
 1334 3846 3970 0.9685 0.9526
BT-20 PD0325901
0.12
uM
LJP6
 72
hr
 1334 3518 3970 0.8860 0.8283
BT-20 PD173074
0.12
uM
LJP6
 72
hr
 1334 3979 3970 1.0022 1.0033
BT-20 PD184352
0.12
uM
LJP5
 72
hr
 1334 4129 3970 1.0398 1.0600
BT-20 Pelitinib
0.12
uM
LJP5
 72
hr
 1334 3802 3970 0.9576 0.9362
BT-20 PF431396
0.12
uM
LJP5
 72
hr
 1334 3260 3970 0.8210 0.7303
BT-20 PF477736
0.12
uM
LJP5
 72
hr
 1334 4033 3970 1.0157 1.0237
BT-20 PF562271
0.12
uM
LJP6
 72
hr
 1334 3540 3970 0.8916 0.8367
BT-20 PHA-665752
0.12
uM
LJP5
 72
hr
 1334 4069 3970 1.0247 1.0372
BT-20 PHA-793887
0.12
uM
LJP6
 72
hr
 1334 2488 3970 0.6266 0.4376