LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 5 of 15: Mean cell count and mean growth rate across biological replicate 2. - Dataset (ID:20241)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | PF431396 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2483 | 5578 | 0.4452 | -0.0197 |
| SK-BR-3 | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1519 | 5578 | 0.2723 | -0.3375 |
| SK-BR-3 | PF562271 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 3045 | 5578 | 0.5460 | 0.1655 |
| SK-BR-3 | PHA-665752 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5667 | 5578 | 1.0158 | 1.0291 |
| SK-BR-3 | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2231 | 5578 | 0.3999 | -0.1029 |
| SK-BR-3 | PI103 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2057 | 5578 | 0.3689 | -0.1601 |
| SK-BR-3 | PLX-4720 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 6085 | 5578 | 1.0909 | 1.1670 |
| SK-BR-3 | QL-X-138 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 2704 | 5578 | 0.4847 | 0.0529 |
| SK-BR-3 | QL-XII-47 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1965 | 5578 | 0.3522 | -0.1906 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2074 | 5578 | 0.3718 | -0.1546 |
| SK-BR-3 | Radicicol | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1944 | 5578 | 0.3486 | -0.1973 |
| SK-BR-3 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5394 | 5578 | 0.9669 | 0.9392 |
| SK-BR-3 | Ruxolitinib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5264 | 5578 | 0.9437 | 0.8964 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5954 | 5578 | 1.0673 | 1.1237 |
| SK-BR-3 | Saracatinib | 1.11 | uM | LJP6 | 72 | hr | 2543 | 4967 | 5578 | 0.8905 | 0.7987 |
| SK-BR-3 | Selumetinib | 1.11 | uM | LJP6 | 72 | hr | 2543 | 5511 | 5578 | 0.9880 | 0.9779 |
| SK-BR-3 | Sirolimus | 1.11 | uM | LJP6 | 72 | hr | 2543 | 3505 | 5578 | 0.6284 | 0.3170 |
| SK-BR-3 | Sorafenib | 1.11 | uM | LJP6 | 72 | hr | 2543 | 5746 | 5578 | 1.0300 | 1.0551 |
| SK-BR-3 | SU11274 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5770 | 5578 | 1.0343 | 1.0630 |
| SK-BR-3 | Fedratinib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5196 | 5578 | 0.9315 | 0.8741 |
| SK-BR-3 | TGX221 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 5742 | 5578 | 1.0293 | 1.0538 |
| SK-BR-3 | Torin1 | 1.11 | uM | LJP6 | 72 | hr | 2543 | 1702 | 5578 | 0.3052 | -0.2770 |
| SK-BR-3 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 2543 | 1616 | 5578 | 0.2898 | -0.3054 |
| SK-BR-3 | Tozasertib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 2014 | 5578 | 0.3610 | -0.1744 |
| SK-BR-3 | Trametinib | 1.11 | uM | LJP5 | 72 | hr | 2543 | 4271 | 5578 | 0.7657 | 0.5693 |